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8J5D
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Cryo-EM structure of starch degradation complex of BAM1-LSF1-MDH
Descriptor: Beta-amylase 1, chloroplastic, Malate dehydrogenase, ...
Authors:Guan, Z.Y, Liu, J, Yan, J.J.
Deposit date:2023-04-21
Release date:2024-01-10
Method:ELECTRON MICROSCOPY (3 Å)
Cite:The LIKE SEX FOUR 1-malate dehydrogenase complex functions as a scaffold to recruit beta-amylase to promote starch degradation.
Plant Cell, 36, 2023
8TO0
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BU of 8to0 by Molmil
48-nm repeating structure of doublets from mouse sperm flagella
Descriptor: Cilia- and flagella- associated protein 210, Cilia- and flagella-associated protein 107, Cilia- and flagella-associated protein 141, ...
Authors:Chen, Z, Shiozak, M, Hass, K.M, Skinner, W, Zhao, S, Guo, C, Polacco, B.J, Yu, Z, Krogan, N.J, Kaake, R.M, Vale, R.D, Agard, D.A.
Deposit date:2023-08-02
Release date:2023-11-01
Last modified:2023-11-22
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:De novo protein identification in mammalian sperm using in situ cryoelectron tomography and AlphaFold2 docking.
Cell, 186, 2023
8I7O
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BU of 8i7o by Molmil
In situ structure of axonemal doublet microtubules in mouse sperm with 16-nm repeat
Descriptor: Cilia and flagella-associated protein 77, Cilia- and flagella-associated protein 20, Cilia- and flagella-associated protein 276, ...
Authors:Zhu, Y, Yin, G.L, Tai, L.H, Sun, F.
Deposit date:2023-02-01
Release date:2023-10-11
Last modified:2023-12-06
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:In-cell structural insight into the stability of sperm microtubule doublet.
Cell Discov, 9, 2023
8I7R
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BU of 8i7r by Molmil
In situ structure of axonemal doublet microtubules in mouse sperm with 48-nm repeat
Descriptor: Cilia and flagella-associated protein 77, Cilia- and flagella-associated protein 107, Cilia- and flagella-associated protein 141, ...
Authors:Zhu, Y, Yin, G.L, Tai, L.H, Sun, F.
Deposit date:2023-02-02
Release date:2023-10-11
Last modified:2023-12-06
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:In-cell structural insight into the stability of sperm microtubule doublet.
Cell Discov, 9, 2023
8P4C
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BU of 8p4c by Molmil
Structural insights into human co-transcriptional capping - structure 3
Descriptor: DNA (32-MER), DNA (41-MER), DNA-directed RNA polymerase II subunit E, ...
Authors:Garg, G, Dienemann, C, Farnung, L, Schwarz, J, Linden, A, Urlaub, H, Cramer, P.
Deposit date:2023-05-20
Release date:2023-08-16
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural insights into human co-transcriptional capping.
Mol.Cell, 83, 2023
8P4B
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BU of 8p4b by Molmil
Structural insights into human co-transcriptional capping - structure 2
Descriptor: DNA (35-MER), DNA (5'-D(P*AP*GP*CP*GP*GP*CP*GP*GP*AP*GP*CP*CP*AP*GP*CP*AP*GP*GP*GP*AP*GP*CP*TP*G)-3'), DNA-directed RNA polymerase II subunit E, ...
Authors:Garg, G, Dienemann, C, Farnung, L, Schwarz, J, Linden, A, Urlaub, H, Cramer, P.
Deposit date:2023-05-20
Release date:2023-08-16
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural insights into human co-transcriptional capping.
Mol.Cell, 83, 2023
8P4D
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BU of 8p4d by Molmil
Structural insights into human co-transcriptional capping - structure 4
Descriptor: DNA (32-MER), DNA (41-MER), DNA-directed RNA polymerase II subunit E, ...
Authors:Garg, G, Dienemann, C, Farnung, L, Schwarz, J, Linden, A, Urlaub, H, Cramer, P.
Deposit date:2023-05-20
Release date:2023-08-16
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural insights into human co-transcriptional capping.
Mol.Cell, 83, 2023
8P4A
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BU of 8p4a by Molmil
Structural insights into human co-transcriptional capping - structure 1
Descriptor: DNA (29-MER), DNA (38-MER), DNA-directed RNA polymerase II subunit E, ...
Authors:Garg, G, Dienemann, C, Farnung, L, Schwarz, J, Linden, A, Urlaub, H, Cramer, P.
Deposit date:2023-05-20
Release date:2023-08-16
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural insights into human co-transcriptional capping.
Mol.Cell, 83, 2023
8P4E
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BU of 8p4e by Molmil
Structural insights into human co-transcriptional capping - structure 5
Descriptor: Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1, DNA (26-MER), DNA (35-MER), ...
Authors:Garg, G, Dienemann, C, Farnung, L, Schwarz, J, Linden, A, Urlaub, H, Cramer, P.
Deposit date:2023-05-20
Release date:2023-07-19
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural insights into human co-transcriptional capping.
Mol.Cell, 2023
8IYJ
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BU of 8iyj by Molmil
Cryo-EM structure of the 48-nm repeat doublet microtubule from mouse sperm
Descriptor: Cilia and flagella-associated protein 77, Cilia- and flagella-associated protein 107, Cilia- and flagella-associated protein 141, ...
Authors:Zhou, L.N, Gui, M, Wu, J.P.
Deposit date:2023-04-05
Release date:2023-07-05
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structures of sperm flagellar doublet microtubules expand the genetic spectrum of male infertility.
Cell, 186, 2023
7Y4E
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BU of 7y4e by Molmil
Crystal structure of DUSP10 mutant_N130A
Descriptor: Dual specificity protein phosphatase 10
Authors:Hu, I.C, Lyu, P.C.
Deposit date:2022-06-14
Release date:2023-06-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Crystal structure of DUSP10 mutant_N130A
To Be Published
7Y4D
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BU of 7y4d by Molmil
Crystal structure of DUSP10 mutant_S95A
Descriptor: Dual specificity protein phosphatase 10
Authors:Hu, I.C, Lyu, P.C.
Deposit date:2022-06-14
Release date:2023-06-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Crystal structure of DUSP10 mutant_S95A
To Be Published
7Y4B
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BU of 7y4b by Molmil
Crystal structure of DUSP10 mutant_D59A
Descriptor: Dual specificity protein phosphatase 10
Authors:Hu, I.C, Lyu, P.C.
Deposit date:2022-06-14
Release date:2023-06-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Crystal structure of DUSP10 mutant_D59A
To Be Published
7Y4C
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BU of 7y4c by Molmil
Crystal structure of DUSP10
Descriptor: Dual specificity protein phosphatase 10
Authors:Hu, I.C, Lyu, P.C.
Deposit date:2022-06-14
Release date:2023-06-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Crystal structure of DUSP10
To Be Published
8GZ4
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BU of 8gz4 by Molmil
Crystal structure of MPXV phosphatase
Descriptor: Dual specificity protein phosphatase H1, PHOSPHATE ION
Authors:Yang, H.T, Wang, W, Huang, H.J, Ji, X.Y.
Deposit date:2022-09-25
Release date:2023-05-17
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:Crystal structure of monkeypox H1 phosphatase, an antiviral drug target.
Protein Cell, 14, 2023
7U4O
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BU of 7u4o by Molmil
Structure of MAP kinase phosphatase 5 in complex with 3,3-dimethyl-1-((9-propyl-5,6-dihydrothieno[3,4-h]quinazolin-2-yl)thio)butan-2-one, an allosteric inhibitor
Descriptor: 3,3-dimethyl-1-{[(9aM)-9-propyl-5,6-dihydrothieno[3,4-h]quinazolin-2-yl]sulfanyl}butan-2-one, Dual specificity protein phosphatase 10
Authors:Gannam, Z.T.K, Jamali, H, Lolis, E, Anderson, K.S, Ellman, J.A, Bennett, A.M.
Deposit date:2022-02-28
Release date:2022-10-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Defining the structure-activity relationship for a novel class of allosteric MKP5 inhibitors.
Eur.J.Med.Chem., 243, 2022
7U4R
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BU of 7u4r by Molmil
Structure of MAP kinase phosphatase 5 in complex with 3,3-dimethyl-1-((9-propyl-5,6-dihydrothieno[2,3-h]quinazolin-2-yl)thio)butan-2-one, an allosteric inhibitor
Descriptor: 3,3-dimethyl-1-{[(9aM)-9-propyl-5,6-dihydrothieno[2,3-h]quinazolin-2-yl]sulfanyl}butan-2-one, Dual specificity protein phosphatase 10
Authors:Gannam, Z.T.K, Jamali, H, Gentzel, E, Lolis, E, Anderson, K.S, Ellman, J.A, Bennett, A.M.
Deposit date:2022-02-28
Release date:2022-10-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.14 Å)
Cite:Defining the structure-activity relationship for a novel class of allosteric MKP5 inhibitors.
Eur.J.Med.Chem., 243, 2022
7UMV
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BU of 7umv by Molmil
Structure of MAP kinase phosphatase 5 in complex with 3,3-dimethyl-1-((5,6-dihydropyrido[2,3-h]quinazolin-2-yl)thio)butan-2-one, an allosteric inhibitor
Descriptor: 1-{[(10aP)-5,6-dihydropyrido[2,3-h]quinazolin-2-yl]sulfanyl}-3,3-dimethylbutan-2-one, ACETATE ION, Dual specificity protein phosphatase 10
Authors:Gannam, Z.T.K, Jamali, H, Lolis, E, Anderson, K.S, Ellman, J.A, Bennett, A.M.
Deposit date:2022-04-07
Release date:2022-10-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Defining the structure-activity relationship for a novel class of allosteric MKP5 inhibitors.
Eur.J.Med.Chem., 243, 2022
7UN4
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BU of 7un4 by Molmil
Structure of MAP kinase phosphatase 5 in complex with 3,3-dimethyl-1-((9-propyl-5,6-dihydrothieno[3,4-h]quinazolin-2-yl)thio)butan-2-one, an allosteric inhibitor
Descriptor: 1-{[(9aM)-5,6-dihydrothieno[2,3-h]quinazolin-2-yl]sulfanyl}-3,3-dimethylbutan-2-one, Dual specificity protein phosphatase 10
Authors:Gannam, Z.T.K, Jamali, H, Lolis, E, Anderson, K.S, Ellman, J.A, Bennett, A.M.
Deposit date:2022-04-08
Release date:2022-10-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Defining the structure-activity relationship for a novel class of allosteric MKP5 inhibitors.
Eur.J.Med.Chem., 243, 2022
7UN0
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BU of 7un0 by Molmil
Structure of MAP kinase phosphatase 5 in complex with 3,3-dimethyl-1-((9-chloro-5,6-dihydrobenzo[h]quinazolin-2-yl)thio)butan-2-one, an allosteric inhibitor
Descriptor: 1-[(9-chlorobenzo[h]quinazolin-2-yl)sulfanyl]-3,3-dimethylbutan-2-one, Dual specificity protein phosphatase 10
Authors:Gannam, Z.T.K, Jamali, H, Lolis, E, Anderson, K.S, Ellman, J.A, Bennett, A.M.
Deposit date:2022-04-08
Release date:2022-10-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Defining the structure-activity relationship for a novel class of allosteric MKP5 inhibitors.
Eur.J.Med.Chem., 243, 2022
7UMU
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BU of 7umu by Molmil
Structure of MAP kinase phosphatase 5 in complex with 3,3-dimethyl-1-((5,6-dihydrobenzo[h]quinazolin-2-yl)thio)butan-2-one, an allosteric inhibitor
Descriptor: 1-[(benzo[h]quinazolin-2-yl)sulfanyl]-3,3-dimethylbutan-2-one, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Dual specificity protein phosphatase 10
Authors:Gannam, Z.T.K, Jamali, H, Lolis, E, Anderson, K.S, Ellman, J.A, Bennett, A.M.
Deposit date:2022-04-07
Release date:2022-10-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Defining the structure-activity relationship for a novel class of allosteric MKP5 inhibitors.
Eur.J.Med.Chem., 243, 2022
7EZN
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BU of 7ezn by Molmil
Crystal structure of CnYvh1 complex with vanadate
Descriptor: 1,2-ETHANEDIOL, Protein-tyrosine-phosphatase, VANADATE ION
Authors:Choi, M.K, Yoo, Y.
Deposit date:2021-06-01
Release date:2022-06-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of CnYvh1 complex with vanadate
To Be Published
7NCY
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BU of 7ncy by Molmil
Dual specificity phosphatase from Sulfolobales Beppu filamentous virus 3
Descriptor: Dual specificity phosphatase, GLYCEROL, NICKEL (II) ION
Authors:Welin, M, Akutsu, M, Hakansson, M, Al-Karadaghi, S, Jasilionis, A, Nordberg Karlsson, E.
Deposit date:2021-01-29
Release date:2022-03-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:Dual specificity phosphatase from Sulfolobales Beppu filamentous virus 3
To Be Published
6L1S
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BU of 6l1s by Molmil
Crystal structure of DUSP22 mutant_C88S
Descriptor: Dual specificity protein phosphatase 22, PHOSPHATE ION
Authors:Lai, C.H, Chang, C.C, Lyu, P.C.
Deposit date:2019-09-30
Release date:2020-10-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.3611 Å)
Cite:Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases.
Int J Mol Sci, 21, 2020
6LMY
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BU of 6lmy by Molmil
Crystal structure of DUSP22 mutant_C88S/S93A
Descriptor: Dual specificity protein phosphatase 22, PHOSPHATE ION
Authors:Lai, C.H, Lyu, P.C.
Deposit date:2019-12-27
Release date:2020-10-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases.
Int J Mol Sci, 21, 2020

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數據於2024-03-27公開中

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