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1CYL
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BU of 1cyl by Molmil
ASPECTS OF RECEPTOR BINDING AND SIGNALLING OF INTERLEUKIN-4 INVESTIGATED BY SITE-DIRECTED MUTAGENESIS AND NMR SPECTROSCOPY
Descriptor: INTERLEUKIN-4
Authors:Mueller, T, Sebald, W, Oschkinat, H.
Deposit date:1994-02-21
Release date:1994-09-30
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Aspects of receptor binding and signalling of interleukin-4 investigated by site-directed mutagenesis and NMR spectroscopy.
J.Mol.Biol., 237, 1994
4YDY
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BU of 4ydy by Molmil
CRYSTAL STRUCTURE OF DARPIN 44C12V5 IN COMPLEX WITH HUMAN IL-4
Descriptor: ACETATE ION, DARPIN 44C12V5, GLYCEROL, ...
Authors:Teplyakov, A, Obmolova, G, Gilliland, G.
Deposit date:2015-02-23
Release date:2015-03-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:CRYSTAL STRUCTURE OF DARPIN 44C12V5 IN COMPLEX WITH HUMAN IL-4
To Be Published
2INT
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BU of 2int by Molmil
CRYSTAL STRUCTURE OF RECOMBINANT HUMAN INTERLEUKIN-4
Descriptor: INTERLEUKIN-4
Authors:Walter, M.R, Cook, W.J, Zhao, B.G, Cameron Junior, R, Ealick, S.E, Walter Junior, R.L, Reichert, P, Nagabhushan, T.L, Trotta, P.P, Bugg, C.E.
Deposit date:1993-07-22
Release date:1994-01-31
Last modified:2019-08-14
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of recombinant human interleukin-4.
J.Biol.Chem., 267, 1992
1RCB
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BU of 1rcb by Molmil
CRYSTAL STRUCTURE OF HUMAN RECOMBINANT INTERLEUKIN-4 AT 2.25 ANGSTROMS RESOLUTION
Descriptor: INTERLEUKIN-4
Authors:Wlodawer, A, Pavlovsky, A, Gustchina, A.
Deposit date:1992-08-26
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of human recombinant interleukin-4 at 2.25 A resolution.
FEBS Lett., 309, 1992
5FHX
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BU of 5fhx by Molmil
CRYSTAL STRUCTURE OF CODV IN COMPLEX WITH IL4 AT 2.55 Ang. RESOLUTION.
Descriptor: Antibody fragment light chain, Interleukin-4, PHOSPHATE ION, ...
Authors:Vallee, F, Dupuy, A, Rak, A.
Deposit date:2015-12-22
Release date:2016-03-30
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:CODV-Ig, a universal bispecific tetravalent and multifunctional immunoglobulin format for medical applications.
Mabs, 8, 2016
1BBN
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BU of 1bbn by Molmil
THREE-DIMENSIONAL SOLUTION STRUCTURE OF HUMAN INTERLEUKIN-4 BY MULTI-DIMENSIONAL HETERONUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
Descriptor: INTERLEUKIN-4
Authors:Clore, G.M, Powers, B, Garrett, D.S, Gronenborn, A.M.
Deposit date:1992-05-01
Release date:1993-10-31
Last modified:2012-09-05
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of human interleukin-4 by multidimensional heteronuclear magnetic resonance spectroscopy.
Science, 256, 1992
1BCN
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BU of 1bcn by Molmil
THREE-DIMENSIONAL SOLUTION STRUCTURE OF HUMAN INTERLEUKIN-4 BY MULTI-DIMENSIONAL HETERONUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
Descriptor: INTERLEUKIN-4
Authors:Clore, G.M, Powers, B, Garrett, D.S, Gronenborn, A.M.
Deposit date:1992-05-01
Release date:1993-10-31
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of human interleukin-4 by multidimensional heteronuclear magnetic resonance spectroscopy.
Science, 256, 1992
8A4F
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BU of 8a4f by Molmil
Human Interleukin-4 mutant - C3T-IL4
Descriptor: Interleukin-4
Authors:Vaz, D.C, Rodrigues, J.R, Mueller, T.D, Sebald, W, Redfield, C, Brito, R.M.M.
Deposit date:2022-06-11
Release date:2023-10-18
Last modified:2024-01-17
Method:SOLUTION NMR
Cite:Lessons on protein structure from interleukin-4: All disulfides are not created equal.
Proteins, 92, 2024
8CH7
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BU of 8ch7 by Molmil
RDC-refined Interleukin-4 (wild type) pH 5.6
Descriptor: Interleukin-4
Authors:Vaz, D.C, Rodrigues, J.R, Loureiro-Ferreira, N, Mueller, T, Sebald, W, Redfield, C, Brito, R.M.M.
Deposit date:2023-02-07
Release date:2023-10-18
Last modified:2024-01-17
Method:SOLUTION NMR
Cite:Lessons on protein structure from interleukin-4: All disulfides are not created equal.
Proteins, 92, 2024
8CGF
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BU of 8cgf by Molmil
Interleukin-4 (wild type) pH 2.4
Descriptor: Interleukin-4
Authors:Vaz, D.C, Rodrigues, J.R, Loureiro-Ferreira, N, Mueller, T, Sebald, W, Redfield, C, Brito, R.M.M.
Deposit date:2023-02-04
Release date:2023-10-18
Last modified:2024-01-17
Method:SOLUTION NMR
Cite:Lessons on protein structure from interleukin-4: All disulfides are not created equal.
Proteins, 92, 2024
1HIK
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BU of 1hik by Molmil
INTERLEUKIN-4 (WILD-TYPE)
Descriptor: INTERLEUKIN-4
Authors:Mueller, T, Buehner, M.
Deposit date:1995-06-01
Release date:1996-01-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Human interleukin-4 and variant R88Q: phasing X-ray diffraction data by molecular replacement using X-ray and nuclear magnetic resonance models.
J.Mol.Biol., 247, 1995
1HIJ
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BU of 1hij by Molmil
INTERLEUKIN-4 MUTANT WITH ARG 88 REPLACED WITH GLN (R88Q)
Descriptor: INTERLEUKIN-4
Authors:Mueller, T, Buehner, M.
Deposit date:1995-06-01
Release date:1996-01-29
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:Human interleukin-4 and variant R88Q: phasing X-ray diffraction data by molecular replacement using X-ray and nuclear magnetic resonance models.
J.Mol.Biol., 247, 1995
1HZI
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BU of 1hzi by Molmil
INTERLEUKIN-4 MUTANT E9A
Descriptor: INTERLEUKIN-4, SULFATE ION
Authors:Hulsmeyer, M, Scheufler, C, Dreyer, M.K.
Deposit date:2001-01-25
Release date:2001-08-29
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure of interleukin 4 mutant E9A suggests polar steering in receptor-complex formation.
Acta Crystallogr.,Sect.D, 57, 2001
1ITL
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BU of 1itl by Molmil
HUMAN INTERLEUKIN 4: THE SOLUTION STRUCTURE OF A FOUR-HELIX-BUNDLE PROTEIN
Descriptor: INTERLEUKIN-4
Authors:Smith, L.J, Redfield, C, Boyd, J, Lawrence, G.M.P, Edwards, R.G, Smith, R.A.G, Dobson, C.M.
Deposit date:1992-02-08
Release date:1993-04-15
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Human interleukin 4. The solution structure of a four-helix bundle protein.
J.Mol.Biol., 224, 1992
1ITM
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BU of 1itm by Molmil
ANALYSIS OF THE SOLUTION STRUCTURE OF HUMAN INTERLEUKIN 4 DETERMINED BY HETERONUCLEAR THREE-DIMENSIONAL NUCLEAR MAGNETIC RESONANCE TECHNIQUES
Descriptor: INTERLEUKIN-4
Authors:Redfield, C, Smith, L.J, Boyd, J, Lawrence, G.M.P, Edwards, R.G, Gershater, C.J, Smith, R.A.G, Dobson, C.M.
Deposit date:1994-02-28
Release date:1994-05-31
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Analysis of the solution structure of human interleukin-4 determined by heteronuclear three-dimensional nuclear magnetic resonance techniques.
J.Mol.Biol., 238, 1994
1ITI
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BU of 1iti by Molmil
THE HIGH RESOLUTION THREE-DIMENSIONAL SOLUTION STRUCTURE OF HUMAN INTERLEUKIN-4 DETERMINED BY MULTI-DIMENSIONAL HETERONUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
Descriptor: INTERLEUKIN-4
Authors:Clore, G.M, Powers, B, Garrett, D.S, Gronenborn, A.M.
Deposit date:1993-04-12
Release date:1993-07-15
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:The high-resolution, three-dimensional solution structure of human interleukin-4 determined by multidimensional heteronuclear magnetic resonance spectroscopy.
Biochemistry, 32, 1993
2B90
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BU of 2b90 by Molmil
Crystal structure of the interleukin-4 variant T13DR85A
Descriptor: Interleukin-4, SULFATE ION
Authors:Kraich, M, Klein, M, Patino, E, Harrer, H, Sebald, W, Mueller, T.D.
Deposit date:2005-10-10
Release date:2006-05-30
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor
Bmc Biol., 4, 2006
2B8U
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BU of 2b8u by Molmil
Crystal structure of wildtype human Interleukin-4
Descriptor: Interleukin-4, SULFATE ION
Authors:Kraich, M, Klein, M, Patino, E, Harrer, H, Sebald, W, Mueller, T.D.
Deposit date:2005-10-10
Release date:2006-05-30
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor
Bmc Biol., 4, 2006
2B8Y
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BU of 2b8y by Molmil
Crystal structure of the interleukin-4 variant T13DF82D
Descriptor: Interleukin-4, SULFATE ION
Authors:Kraich, M, Klein, M, Patino, E, Harrer, H, Sebald, W, Mueller, T.D.
Deposit date:2005-10-10
Release date:2006-05-30
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor
Bmc Biol., 4, 2006
2B91
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BU of 2b91 by Molmil
Crystal structure of the interleukin-4 variant F82DR85A
Descriptor: Interleukin-4, SULFATE ION
Authors:Kraich, M, Klein, M, Patino, E, Harrer, H, Sebald, W, Mueller, T.D.
Deposit date:2005-10-10
Release date:2006-05-30
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor
Bmc Biol., 4, 2006
2B8Z
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BU of 2b8z by Molmil
Crystal structure of the interleukin-4 variant R85A
Descriptor: Interleukin-4, SULFATE ION
Authors:Kraich, M, Klein, M, Patino, E, Harrer, H, Sebald, W, Mueller, T.D.
Deposit date:2005-10-10
Release date:2006-05-30
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor
Bmc Biol., 4, 2006
2B8X
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BU of 2b8x by Molmil
Crystal structure of the interleukin-4 variant F82D
Descriptor: Interleukin-4, SULFATE ION
Authors:Kraich, M, Klein, M, Patino, E, Harrer, H, Sebald, W, Mueller, T.D.
Deposit date:2005-10-10
Release date:2006-05-30
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor
Bmc Biol., 4, 2006
2CYK
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BU of 2cyk by Molmil
ASPECTS OF RECEPTOR BINDING AND SIGNALLING OF INTERLEUKIN-4 INVESTIGATED BY SITE-DIRECTED MUTAGENESIS AND NMR SPECTROSCOPY
Descriptor: INTERLEUKIN-4
Authors:Mueller, T, Sebald, W, Oschkinat, H.
Deposit date:1994-08-16
Release date:1994-12-20
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Aspects of receptor binding and signalling of interleukin-4 investigated by site-directed mutagenesis and NMR spectroscopy.
J.Mol.Biol., 237, 1994
2D48
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BU of 2d48 by Molmil
Crystal structure of the Interleukin-4 variant T13D
Descriptor: Interleukin-4, SULFATE ION
Authors:Kraich, M, Klein, M, Patino, E, Harrer, H, Sebald, W, Mueller, T.D.
Deposit date:2005-10-11
Release date:2006-05-30
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor
Bmc Biol., 4, 2006
6OEL
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BU of 6oel by Molmil
Engineered Fab bound to IL-4 receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common subunit gamma, Interleukin-4 receptor subunit alpha, ...
Authors:Jude, K.M, Moraga, I, Spangler, J.B, Garcia, K.C.
Deposit date:2019-03-27
Release date:2019-08-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A strategy for the selection of monovalent antibodies that span protein dimer interfaces.
J.Biol.Chem., 294, 2019

 

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數據於2024-03-27公開中

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