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7FC9
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BU of 7fc9 by Molmil
Crystal structure of CmABCB1 in lipidic mesophase revealed by LCP-SFX
Descriptor: ACETATE ION, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Pan, D, Oyama, R, Sato, T, Nakane, T, Mizunuma, R, Matsuoka, K, Joti, Y, Tono, K, Nango, E, Iwata, S, Nakatsu, T, Kato, H.
Deposit date:2021-07-14
Release date:2022-02-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of CmABCB1 multi-drug exporter in lipidic mesophase revealed by LCP-SFX.
Iucrj, 9, 2022
5EG1
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BU of 5eg1 by Molmil
Antibacterial peptide ABC transporter McjD with a resolved lipid
Descriptor: (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, MAGNESIUM ION, Microcin-J25 export ATP-binding/permease protein McjD, ...
Authors:Choudhury, H.G, Beis, K.
Deposit date:2015-10-26
Release date:2016-08-31
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.42 Å)
Cite:Structural and Functional Basis for Lipid Synergy on the Activity of the Antibacterial Peptide ABC Transporter McjD.
J.Biol.Chem., 291, 2016
2ONJ
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BU of 2onj by Molmil
Structure of the multidrug ABC transporter Sav1866 from S. aureus in complex with AMP-PNP
Descriptor: Multidrug export ATP-binding/permease protein SAV1866, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SODIUM ION
Authors:Dawson, R.J.P, Locher, K.P.
Deposit date:2007-01-24
Release date:2007-03-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structure of the multidrug ABC transporter Sav1866 from Staphylococcus aureus in complex with AMP-PNP.
Febs Lett., 581, 2007
2HYD
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BU of 2hyd by Molmil
Multidrug ABC transporter SAV1866
Descriptor: ABC transporter homolog, ADENOSINE-5'-DIPHOSPHATE, SODIUM ION
Authors:Dawson, R.J.P, Locher, K.P.
Deposit date:2006-08-05
Release date:2006-09-05
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of a bacterial multidrug ABC transporter.
Nature, 443, 2006
3QF4
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BU of 3qf4 by Molmil
Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation
Descriptor: ABC transporter, ATP-binding protein, MAGNESIUM ION, ...
Authors:Hohl, M, Briand, C, Gruetter, M.G, Seeger, M.A.
Deposit date:2011-01-21
Release date:2012-03-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation
Nat.Struct.Mol.Biol., 19, 2012
3B5X
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BU of 3b5x by Molmil
Crystal Structure of MsbA from Vibrio cholerae
Descriptor: Lipid A export ATP-binding/permease protein msbA
Authors:Ward, A, Reyes, C.L, Yu, J, Roth, C.B, Chang, G.
Deposit date:2007-10-26
Release date:2007-12-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (5.5 Å)
Cite:Flexibility in the ABC transporter MsbA: Alternating access with a twist.
Proc.Natl.Acad.Sci.Usa, 104, 2007
4RY2
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BU of 4ry2 by Molmil
Crystal structure of the peptidase-containing ABC transporter PCAT1
Descriptor: ABC-type bacteriocin transporter
Authors:Lin, D.L, Huang, S, Chen, J.
Deposit date:2014-12-13
Release date:2015-07-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.611 Å)
Cite:Crystal structures of a polypeptide processing and secretion transporter.
Nature, 523, 2015
4S0F
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BU of 4s0f by Molmil
Crystal structure of the peptidase-containing ABC transporter PCAT1 E648Q mutant complexed with ATPgS in an occluded conformation
Descriptor: ABC-type bacteriocin transporter, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
Authors:Lin, D.L, Huang, S, Chen, J.
Deposit date:2014-12-30
Release date:2015-07-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (5.515 Å)
Cite:Crystal structures of a polypeptide processing and secretion transporter.
Nature, 523, 2015
6FN4
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BU of 6fn4 by Molmil
Apo form of UIC2 Fab complex of human-mouse chimeric ABCB1 (ABCB1HM)
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Apo form of Human-mouse chimeric ABCB1 (ABCB1HM) in complex with Antigen binding fragment of UIC2., ...
Authors:Alam, A, Locher, K.P.
Deposit date:2018-02-02
Release date:2018-02-21
Last modified:2021-06-02
Method:ELECTRON MICROSCOPY (4.14 Å)
Cite:Structure of a zosuquidar and UIC2-bound human-mouse chimeric ABCB1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6GDI
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BU of 6gdi by Molmil
Structure of P-glycoprotein(ABCB1) in the post-hydrolytic state
Descriptor: Multidrug resistance protein 1A
Authors:Ford, R.C, Thonghin, N, Collins, R.F, Barbieri, A, Shafi, T, Siebert, A.
Deposit date:2018-04-23
Release date:2018-05-23
Last modified:2019-04-03
Method:ELECTRON MICROSCOPY (7.9 Å)
Cite:Novel features in the structure of P-glycoprotein (ABCB1) in the post-hydrolytic state as determined at 7.9 angstrom resolution.
Bmc Struct.Biol., 18, 2018
6FN1
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BU of 6fn1 by Molmil
Zosuquidar and UIC2 Fab complex of human-mouse chimeric ABCB1 (ABCB1HM)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Human-mouse chimeric ABCB1 (ABCBHM), UIC2 Antigen Binding Fragment Heavy Chain, ...
Authors:Alam, A, Locher, K.P.
Deposit date:2018-02-02
Release date:2018-02-21
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Structure of a zosuquidar and UIC2-bound human-mouse chimeric ABCB1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4KSD
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BU of 4ksd by Molmil
Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain
Descriptor: Multidrug resistance protein 1A, R2 protein
Authors:Ward, A, Szewczyk, P, Grimard, V, Lee, C.-W, Martinez, L, Doshi, R, Caya, A, Villaluz, M, Pardon, E, Cregger, C, Swartz, D.J, Falson, P, Urbatsch, I, Govaerts, C, Steyaert, J, Chang, G.
Deposit date:2013-05-17
Release date:2013-07-31
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (4.1001 Å)
Cite:Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KSC
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BU of 4ksc by Molmil
Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain
Descriptor: Multidrug resistance protein 1A
Authors:Ward, A, Szewczyk, P, Grimard, V, Lee, C.-W, Martinez, L, Doshi, R, Caya, A, Villaluz, M, Pardon, E, Cregger, C, Swartz, D.J, Falson, P, Urbatsch, I, Govaerts, C, Steyaert, J, Chang, G.
Deposit date:2013-05-17
Release date:2013-07-31
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KSB
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BU of 4ksb by Molmil
Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain
Descriptor: Multidrug resistance protein 1A
Authors:Ward, A, Szewczyk, P, Grimard, V, Lee, C.-W, Martinez, L, Doshi, R, Caya, A, Villaluz, M, Pardon, E, Cregger, C, Swartz, D.J, Falson, P, Urbatsch, I, Govaerts, C, Steyaert, J, Chang, G.
Deposit date:2013-05-17
Release date:2013-07-31
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.8001 Å)
Cite:Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain.
Proc.Natl.Acad.Sci.USA, 110, 2013
4XWK
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BU of 4xwk by Molmil
P-glycoprotein co-crystallized with BDE-100
Descriptor: 2,4-dibromophenyl 2,4,6-tribromophenyl ether, Multidrug resistance protein 1A
Authors:McGrath, A.P, Rees, S.D, Chang, G.
Deposit date:2015-01-28
Release date:2016-04-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Global marine pollutants inhibit P-glycoprotein: Environmental levels, inhibitory effects, and cocrystal structure.
Sci Adv, 2, 2016
4AYX
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BU of 4ayx by Molmil
STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10 (ROD FORM B)
Descriptor: ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, CARDIOLIPIN, DODECYL-BETA-D-MALTOSIDE, ...
Authors:Pike, A.C.W, Shintre, C.A, Li, Q, Kim, J, von Delft, F, Barr, A.J, Das, S, Chaikuad, A, Xia, X, Quigley, A, Dong, Y, Dong, L, Krojer, T, Vollmar, M, Muniz, J.R.C, Bray, J.E, Berridge, G, Chalk, R, Gileadi, O, Burgess-Brown, N, Shrestha, L, Goubin, S, Yang, J, Mahajan, P, Mukhopadhyay, S, Bullock, A.N, Arrowsmith, C.H, Weigelt, J, Bountra, C, Edwards, A.M, Carpenter, E.P.
Deposit date:2012-06-22
Release date:2012-07-11
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of Abcb10, a Human ATP-Binding Cassette Transporter in Apo- and Nucleotide-Bound States
Proc.Natl.Acad.Sci.USA, 110, 2013
4AYW
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BU of 4ayw by Molmil
STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10 (PLATE FORM)
Descriptor: ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, CHOLESTEROL HEMISUCCINATE, DODECYL-BETA-D-MALTOSIDE, ...
Authors:Pike, A.C.W, Shintre, C.A, Li, Q, Kim, J, von Delft, F, Barr, A.J, Das, S, Chaikuad, A, Xia, X, Quigley, A, Dong, Y, Dong, L, Krojer, T, Vollmar, M, Muniz, J.R.C, Bray, J.E, Berridge, G, Chalk, R, Gileadi, O, Burgess-Brown, N, Shrestha, L, Goubin, S, Yang, J, Mahajan, P, Mukhopadhyay, S, Bullock, A.N, Arrowsmith, C.H, Weigelt, J, Bountra, C, Edwards, A.M, Carpenter, E.P.
Deposit date:2012-06-22
Release date:2012-07-11
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structures of Abcb10, a Human ATP-Binding Cassette Transporter in Apo- and Nucleotide-Bound States
Proc.Natl.Acad.Sci.USA, 110, 2013
4AYT
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BU of 4ayt by Molmil
STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10
Descriptor: ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10 MITOCHONDRIAL, CARDIOLIPIN, DODECYL-BETA-D-MALTOSIDE, ...
Authors:Pike, A.C.W, Shintre, C.A, Li, Q, Kim, J, von Delft, F, Barr, A.J, Das, S, Chaikuad, A, Xia, X, Quigley, A, Dong, Y, Dong, L, Krojer, T, Vollmar, M, Muniz, J.R.C, Bray, J.E, Berridge, G, Chalk, R, Gileadi, O, Burgess-Brown, N, Shrestha, L, Goubin, S, Yang, J, Mahajan, P, Mukhopadhyay, S, Bullock, A.N, Arrowsmith, C.H, Weigelt, J, Bountra, C, Edwards, A.M, Carpenter, E.P.
Deposit date:2012-06-22
Release date:2012-07-11
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structures of Abcb10, a Human ATP-Binding Cassette Transporter in Apo- and Nucleotide-Bound States
Proc.Natl.Acad.Sci.USA, 110, 2013
5C76
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BU of 5c76 by Molmil
ATP-driven lipid-linked oligosaccharide flippase PglK in apo-inward facing state (2)
Descriptor: WlaB protein
Authors:Perez, C, Gerber, S, Locher, K.P.
Deposit date:2015-06-24
Release date:2015-08-19
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.94 Å)
Cite:Structure and mechanism of an active lipid-linked oligosaccharide flippase.
Nature, 524, 2015
5C73
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BU of 5c73 by Molmil
ATP-driven lipid-linked oligosaccharide flippase PglK in outward-occluded conformation
Descriptor: Protein glycosylation K
Authors:Perez, C, Locher, K.P.
Deposit date:2015-06-24
Release date:2015-08-19
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (5.9 Å)
Cite:Structure and mechanism of an active lipid-linked oligosaccharide flippase.
Nature, 524, 2015
5C78
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BU of 5c78 by Molmil
ATP-driven lipid-linked oligosaccharide flippase PglK in apo-inward state (1)
Descriptor: ATP-driven flippase PglK, PENTAETHYLENE GLYCOL
Authors:Perez, C, Locher, K.P.
Deposit date:2015-06-24
Release date:2015-08-19
Last modified:2015-09-02
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure and mechanism of an active lipid-linked oligosaccharide flippase.
Nature, 524, 2015
4F4C
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BU of 4f4c by Molmil
The Crystal Structure of the Multi-Drug Transporter
Descriptor: Multidrug resistance protein pgp-1, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, undecyl 4-O-alpha-D-glucopyranosyl-1-thio-beta-D-glucopyranoside
Authors:Jin, M.S, Oldham, M.L, Zhang, Q, Chen, J.
Deposit date:2012-05-10
Release date:2012-09-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal structure of the multidrug transporter P-glycoprotein from Caenorhabditis elegans.
Nature, 490, 2012
6HRC
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BU of 6hrc by Molmil
Outward-facing PglK with ATPgammaS bound
Descriptor: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, WlaB protein
Authors:Perez, C, Locher, K.P.
Deposit date:2018-09-26
Release date:2019-03-06
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of Outward-Facing PglK and Molecular Dynamics of Lipid-Linked Oligosaccharide Recognition and Translocation.
Structure, 27, 2019
6JB1
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BU of 6jb1 by Molmil
Structure of pancreatic ATP-sensitive potassium channel bound with repaglinide and ATPgammaS at 3.3A resolution
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ...
Authors:Chen, L, Ding, D, Wang, M, Wu, J.-X, Kang, Y.
Deposit date:2019-01-25
Release date:2019-05-22
Last modified:2021-09-29
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:The Structural Basis for the Binding of Repaglinide to the Pancreatic KATPChannel.
Cell Rep, 27, 2019
5MKK
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Crystal structure of the heterodimeric ABC transporter TmrAB, a homolog of the antigen translocation complex TAP
Descriptor: Multidrug resistance ABC transporter ATP-binding and permease protein, SULFATE ION
Authors:Noell, A, Thomas, C, Tomasiak, T.M, Olieric, V, Wang, M, Diederichs, K, Stroud, R.M, Pos, K.M, Tampe, R.
Deposit date:2016-12-05
Release date:2017-01-18
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure and mechanistic basis of a functional homolog of the antigen transporter TAP.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017

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數據於2024-04-17公開中

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