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6VNZ
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BU of 6vnz by Molmil
NMR solution structure of tamapin, mutant K20A
Descriptor: Potassium channel toxin alpha-KTx 5.4
Authors:del Rio Portilla, F, Melchor Meneses, C.M, Mayorga Flores, M.
Deposit date:2020-01-29
Release date:2020-07-29
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Novel Blocker of Onco SK3 Channels Derived from Scorpion Toxin Tamapin and Active against Migration of Cancer Cells.
Acs Med.Chem.Lett., 11, 2020
1AGT
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BU of 1agt by Molmil
SOLUTION STRUCTURE OF THE POTASSIUM CHANNEL INHIBITOR AGITOXIN 2: CALIPER FOR PROBING CHANNEL GEOMETRY
Descriptor: AGITOXIN 2
Authors:Krezel, A.M, Kasibhatla, C, Hidalgo, P, Mackinnon, R, Wagner, G.
Deposit date:1995-04-14
Release date:1995-07-10
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of the potassium channel inhibitor agitoxin 2: caliper for probing channel geometry.
Protein Sci., 4, 1995
6GGZ
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BU of 6ggz by Molmil
NMR structure of the scorpion toxin AmmTx3
Descriptor: Potassium channel toxin alpha-KTx 15.3
Authors:Landon, C, Meudal, H.
Deposit date:2018-05-04
Release date:2019-01-30
Last modified:2020-03-11
Method:SOLUTION NMR
Cite:Synthesis by native chemical ligation and characterization of the scorpion toxin AmmTx3.
Bioorg. Med. Chem., 27, 2019
3ODV
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BU of 3odv by Molmil
X-ray structure of kaliotoxin by racemic protein crystallography
Descriptor: CITRIC ACID, Potassium channel toxin alpha-KTx 3.1, trifluoroacetic acid
Authors:Pentelute, B.L, Mandal, K, Gates, Z.P, Sawaya, M.R, Yeates, T.O, Kent, S.B.H.
Deposit date:2010-08-11
Release date:2010-10-20
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:Total chemical synthesis and X-ray structure of kaliotoxin by racemic protein crystallography.
Chem.Commun.(Camb.), 46, 2010
6MZT
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BU of 6mzt by Molmil
Solution structure of alpha-KTx-6.21 (UroTx) from Urodacus yaschenkoi
Descriptor: Potassium channel toxin alpha-KTx 6.21
Authors:Chin, Y.K.-Y, Luna-Ramirez, K, Anangi, R, King, G.F.
Deposit date:2018-11-05
Release date:2020-03-11
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural basis of the potency and selectivity of Urotoxin, a potent Kv1 blocker from scorpion venom.
Biochem. Pharmacol., 174, 2020
3E8Y
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BU of 3e8y by Molmil
Xray structure of scorpion toxin BmBKTx1
Descriptor: CHLORIDE ION, Potassium channel toxin alpha-KTx 19.1, SULFATE ION
Authors:Mandal, K, Pentelute, B.L, Tereshko, V, Kossiakoff, A.A, Kent, S.B.H.
Deposit date:2008-08-20
Release date:2009-02-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:X-ray structure of native scorpion toxin BmBKTx1 by racemic protein crystallography using direct methods.
J.Am.Chem.Soc., 131, 2009
1BKT
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BU of 1bkt by Molmil
BMKTX TOXIN FROM SCORPION BUTHUS MARTENSII KARSCH, NMR, 25 STRUCTURES
Descriptor: BMKTX
Authors:Renisio, J.G, Romi-Lebrun, R, Blanc, E, Bornet, O, Nakajima, T, Darbon, H.
Deposit date:1998-07-03
Release date:1999-01-13
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structure of BmKTX, a K+ blocker toxin from the Chinese scorpion Buthus Martensi
Proteins, 38, 2000
1CMR
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BU of 1cmr by Molmil
NMR SOLUTION STRUCTURE OF A CHIMERIC PROTEIN, DESIGNED BY TRANSFERRING A FUNCTIONAL SNAKE BETA-HAIRPIN INTO A SCORPION ALPHA/BETA SCAFFOLD (PH 3.5, 20C), NMR, 18 STRUCTURES
Descriptor: CHARYBDOTOXIN, ALPHA CHIMERA
Authors:Zinn-Justin, S, Guenneugues, M, Drakopoulou, E, Gilquin, B, Vita, C, Menez, A.
Deposit date:1996-03-15
Release date:1996-08-01
Last modified:2021-11-03
Method:SOLUTION NMR
Cite:Transfer of a beta-hairpin from the functional site of snake curaremimetic toxins to the alpha/beta scaffold of scorpion toxins: three-dimensional solution structure of the chimeric protein.
Biochemistry, 35, 1996
2K4U
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BU of 2k4u by Molmil
Solution structure of the SCORPION TOXIN ADWX-1
Descriptor: Potassium channel toxin alpha-KTx 3.6
Authors:Yin, S.J, Jiang, L, Yi, H, Han, S, Yang, D.W, Liu, M.L, Liu, H, Cao, Z.J, Wu, Y.L, Li, W.X.
Deposit date:2008-06-18
Release date:2008-12-09
Last modified:2021-11-10
Method:SOLUTION NMR
Cite:Different Residues in Channel Turret Determining the Selectivity of ADWX-1 Inhibitor Peptide between Kv1.1 and Kv1.3 Channels
J.Proteome Res., 7, 2008
2K9O
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BU of 2k9o by Molmil
Solution structure of Vm24 synthetic scorpion toxin
Descriptor: Vm24 SCORPION toxin
Authors:del Rio-Portilla, F, Hernandez-Lopez, R, Possani-Postay, L, Gurrola, G.
Deposit date:2008-10-20
Release date:2009-11-03
Last modified:2014-05-28
Method:SOLUTION NMR
Cite:Structure, function, and chemical synthesis of Vaejovis mexicanus peptide 24: a novel potent blocker of Kv1.3 potassium channels of human T lymphocytes.
Biochemistry, 51, 2012
2KTX
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BU of 2ktx by Molmil
COMPLETE KALIOTOXIN FROM ANDROCTONUS MAURETANICUS MAURETANICUS, NMR, 18 STRUCTURES
Descriptor: KALIOTOXIN
Authors:Gairi, M, Romi, R, Fernandez, I, Rochat, H, Martin-Eauclaire, M.-F, Van Rietschtoten, J, Pons, M, Giralt, E.
Deposit date:1997-02-27
Release date:1997-06-16
Last modified:2017-12-20
Method:SOLUTION NMR
Cite:3D structure of kaliotoxin: is residue 34 a key for channel selectivity?
J.Pept.Sci., 3, 1997
2KY3
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BU of 2ky3 by Molmil
Solution structure of GS-alfa-Ktx5.4 synthetic scorpion like
Descriptor: Potassium channel toxin alpha-KTx 5.4
Authors:Del Rio-Portilla, F, Ramirez-Cordero, B.E, Brieba-De Castro, L.
Deposit date:2010-05-14
Release date:2011-06-01
Last modified:2020-02-05
Method:SOLUTION NMR
Cite:Cytotoxicity of recombinant tamapin and related toxin-like peptides on model cell lines.
Chem.Res.Toxicol., 27, 2014
1BAH
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BU of 1bah by Molmil
A TWO DISULFIDE DERIVATIVE OF CHARYBDOTOXIN WITH DISULFIDE 13-33 REPLACED BY TWO ALPHA-AMINOBUTYRIC ACIDS, NMR, 30 STRUCTURES
Descriptor: CHARYBDOTOXIN
Authors:Song, J, Gilquin, B, Jamin, N, Guenneugues, M, Dauplais, M, Vita, C, Menez, A.
Deposit date:1996-06-06
Release date:1997-01-11
Last modified:2020-01-15
Method:SOLUTION NMR
Cite:NMR solution structure of a two-disulfide derivative of charybdotoxin: structural evidence for conservation of scorpion toxin alpha/beta motif and its hydrophobic side chain packing.
Biochemistry, 36, 1997
1BIG
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BU of 1big by Molmil
SCORPION TOXIN BMTX1 FROM BUTHUS MARTENSII KARSCH, NMR, 25 STRUCTURES
Descriptor: TOXIN BMTX1
Authors:Blanc, E, Romi-Lebrun, R, Bornet, O, Nakajima, T, Darbon, H.
Deposit date:1998-06-16
Release date:1999-01-13
Last modified:2019-12-25
Method:SOLUTION NMR
Cite:Solution structure of two new toxins from the venom of the Chinese scorpion Buthus martensi Karsch blockers of potassium channels.
Biochemistry, 37, 1998
1C49
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BU of 1c49 by Molmil
STRUCTURAL AND FUNCTIONAL DIFFERENCES OF TWO TOXINS FROM THE SCORPION PANDINUS IMPERATOR
Descriptor: TOXIN K-BETA
Authors:Klenk, K.C, Tenenholz, T.C, Matteson, D.R, Rogowski, R.S, Blaustein, M.P, Weber, D.J.
Deposit date:1999-08-17
Release date:2000-03-22
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Structural and functional differences of two toxins from the scorpion Pandinus imperator.
Proteins, 38, 2000
1C55
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BU of 1c55 by Molmil
NMR SOLUTION STRUCTURE OF BUTANTOXIN
Descriptor: BUTANTOXIN
Authors:Holaday Jr, S.K, Martin, B.M, Fletcher Jr, P.L, Krishna, N.R.
Deposit date:1999-10-19
Release date:2000-07-19
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:NMR solution structure of butantoxin.
Arch.Biochem.Biophys., 379, 2000
1C56
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BU of 1c56 by Molmil
NMR SOLUTION STRUCTURE OF BUTANTOXIN
Descriptor: BUTANTOXIN
Authors:Holaday Jr, S.K, Martin, B.M, Fletcher Jr, P.L, Krishna, N.R.
Deposit date:1999-10-25
Release date:2000-07-19
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:NMR solution structure of butantoxin.
Arch.Biochem.Biophys., 379, 2000
2AXK
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BU of 2axk by Molmil
Solution structure of discrepin, a scorpion venom toxin blocking K+ channels.
Descriptor: discrepin
Authors:Prochnicka-Chalufour, A, Corzo, G, Satake, H, Martin-Eauclaire, M.-F, Murgia, A.R, Prestipino, G, D'Suze, G, Possani, L.D, Delepierre, M.
Deposit date:2005-09-05
Release date:2006-06-20
Last modified:2019-12-25
Method:SOLUTION NMR
Cite:Solution structure of discrepin, a new K+-channel blocking peptide from the alpha-KTx15 subfamily.
Biochemistry, 45, 2006
2BMT
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BU of 2bmt by Molmil
SCORPION TOXIN BMTX2 FROM BUTHUS MARTENSII KARSCH, NMR, 25 STRUCTURES
Descriptor: TOXIN BMTX2
Authors:Blanc, E, Romi-Lebrun, R, Bornet, O, Nakajima, T, Darbon, H.
Deposit date:1998-06-16
Release date:1999-01-13
Last modified:2019-12-25
Method:SOLUTION NMR
Cite:Solution structure of two new toxins from the venom of the Chinese scorpion Buthus martensi Karsch blockers of potassium channels.
Biochemistry, 37, 1998
2CK5
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BU of 2ck5 by Molmil
Solution structure of Delta 1-7 aOSK1
Descriptor: POTASSIUM CHANNEL TOXIN ALPHA-KTX 3.7
Authors:Alphonse, S, Mouhat, S, Sabatier, J.M, Darbon, H, Bernard, C.
Deposit date:2006-04-10
Release date:2007-05-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of Two Analogues of the Osk1 Toxin
To be Published
2CRD
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BU of 2crd by Molmil
ANALYSIS OF SIDE-CHAIN ORGANIZATION ON A REFINED MODEL OF CHARYBDOTOXIN: STRUCTURAL AND FUNCTIONAL IMPLICATIONS
Descriptor: CHARYBDOTOXIN
Authors:Bontems, F, Roumestand, C, Gilquin, B, Menez, A, Toma, F.
Deposit date:1993-02-17
Release date:1993-07-15
Last modified:2019-12-25
Method:SOLUTION NMR
Cite:Analysis of side-chain organization on a refined model of charybdotoxin: structural and functional implications.
Biochemistry, 31, 1992
2CK4
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BU of 2ck4 by Molmil
Solution Structure of aOSK1
Descriptor: POTASSIUM CHANNEL TOXIN ALPHA-KTX 3.7
Authors:Alphonse, S, Mouhat, S, Sabatier, J.M, Darbon, H, Bernard, C.
Deposit date:2006-04-10
Release date:2007-05-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of Two Analogues of the Osk1 Toxin
To be Published
1HP2
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BU of 1hp2 by Molmil
SOLUTION STRUCTURE OF A TOXIN FROM THE SCORPION TITYUS SERRULATUS (TSTX-K ALPHA) DETERMINED BY NMR.
Descriptor: TITYUSTOXIN K ALPHA
Authors:Ellis, K.C, Tenenholz, T.C, Gilly, W.F, Blaustein, M.P, Weber, D.J.
Deposit date:2000-12-12
Release date:2001-06-13
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Interaction of a toxin from the scorpion Tityus serrulatus with a cloned K+ channel from squid (sqKv1A).
Biochemistry, 40, 2001
1HLY
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BU of 1hly by Molmil
SOLUTION STRUCTURE OF HONGOTOXIN 1
Descriptor: HONGOTOXIN 1
Authors:Pragl, B, Koschak, A, Trieb, M, Obermair, G, Kaufmann, W.A, Gerster, U, Blanc, E, Hahn, C, Prinz, H, Schutz, G, Darbon, H, Gruber, H.J, Knaus, H.G.
Deposit date:2000-12-04
Release date:2003-09-30
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Synthesis, characterization, and application of cy-dye- and alexa-dye-labeled hongotoxin(1) analogues. The first high affinity fluorescence probes for voltage-gated K+ channels.
BIOCONJUG.CHEM., 13, 2002
1J5J
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BU of 1j5j by Molmil
Solution structure of HERG-specific scorpion toxin BeKm-1
Descriptor: BeKm-1 toxin
Authors:Korolokova, Y.V, Bocharov, E.V, Angelo, K, Maslennikov, I.V, Grinenko, O.V, Lipkin, A.V, Nosireva, E.D, Pluzhnikov, K.A, Olesen, S.-P, Arseniev, A.S, Grishin, E.V.
Deposit date:2002-04-16
Release date:2002-11-20
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:New binding site on common molecular scaffold provides HERG channel specificity of scorpion toxin BeKm-1.
J.Biol.Chem., 277, 2002

 

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數據於2024-03-27公開中

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