4V4N
 
 | | Structure of the Methanococcus jannaschii ribosome-SecYEBeta channel complex | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein L7AE, ... | | Authors: | Menetret, J.F, Park, E, Gumbart, J.C, Ludtke, S.J, Li, W, Whynot, A, Rapoport, T.A, Akey, C.W. | | Deposit date: | 2013-06-17 | | Release date: | 2014-07-09 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (9 Å) | | Cite: | Structure of the SecY channel during initiation of protein translocation.
Nature, 506, 2013
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6Z3T
 | | Structure of canine Sec61 inhibited by mycolactone | | Descriptor: | Protein transport protein Sec61 subunit alpha isoform 1, Protein transport protein Sec61 subunit beta, Protein transport protein Sec61 subunit gamma, ... | | Authors: | Gerard, S.F, Higgins, M.K. | | Deposit date: | 2020-05-21 | | Release date: | 2020-07-22 | | Last modified: | 2020-08-19 | | Method: | ELECTRON MICROSCOPY (2.69 Å) | | Cite: | Structure of the Inhibited State of the Sec Translocon.
Mol.Cell, 79, 2020
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2AKI
 | | Normal mode-based flexible fitted coordinates of a translocating SecYEG protein-conducting channel into the cryo-EM map of a SecYEG-nascent chain-70S ribosome complex from E. coli | | Descriptor: | Preprotein translocase secE subunit, Preprotein translocase secY subunit, Protein-export membrane protein secG | | Authors: | Mitra, K, Schaffitzel, C, Shaikh, T, Tama, F, Jenni, S, Brooks III, C.L, Ban, N, Frank, J. | | Deposit date: | 2005-08-03 | | Release date: | 2005-11-15 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (14.9 Å) | | Cite: | Structure of the E. coli protein-conducting channel bound to a translating ribosome.
Nature, 438, 2005
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2AKH
 | | Normal mode-based flexible fitted coordinates of a non-translocating SecYEG protein-conducting channel into the cryo-EM map of a SecYEG-nascent chain-70S ribosome complex from E. coli | | Descriptor: | Preprotein translocase secE subunit, Preprotein translocase secY subunit, Protein-export membrane protein secG | | Authors: | Mitra, K.M, Schaffitzel, C, Shaikh, T, Tama, F, Jenni, S, Brooks III, C.L, Ban, N, Frank, J. | | Deposit date: | 2005-08-03 | | Release date: | 2005-11-15 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (14.9 Å) | | Cite: | Structure of the E. coli protein-conducting channel bound to a translating ribosome.
Nature, 438, 2005
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6R7L
 | | Ribosome-bound SecYEG translocon in a nanodisc | | Descriptor: | Protein translocase subunit SecY, SecE,Protein translocase subunit SecE,Protein translocase subunit SecE,Protein translocase subunit SecE, SecG | | Authors: | Kater, L, Beckmann, R, Kedrov, A. | | Deposit date: | 2019-03-29 | | Release date: | 2019-08-07 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (6 Å) | | Cite: | Partially inserted nascent chain unzips the lateral gate of the Sec translocon.
Embo Rep., 20, 2019
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5MG3
 | | EM fitted model of bacterial holo-translocon | | Descriptor: | Membrane protein insertase YidC, Protein translocase subunit SecD, Protein translocase subunit SecE, ... | | Authors: | Schaffitzel, C, Botte, M. | | Deposit date: | 2016-11-20 | | Release date: | 2016-12-28 | | Last modified: | 2017-08-02 | | Method: | ELECTRON MICROSCOPY (14 Å) | | Cite: | A central cavity within the holo-translocon suggests a mechanism for membrane protein insertion.
Sci Rep, 6, 2016
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6ITC
 | | Structure of a substrate engaged SecA-SecY protein translocation machine | | Descriptor: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ... | | Authors: | Ma, C.Y, Wu, X.F, Sun, D.J, Park, E.Y, Rapoport, T.A, Gao, N, Long, L. | | Deposit date: | 2018-11-21 | | Release date: | 2019-06-12 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (3.45 Å) | | Cite: | Structure of the substrate-engaged SecA-SecY protein translocation machine.
Nat Commun, 10, 2019
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5EUL
 | | Structure of the SecA-SecY complex with a translocating polypeptide substrate | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, AYC08, BERYLLIUM TRIFLUORIDE ION, ... | | Authors: | Li, L, Park, E, Ling, J, Ingram, J, Ploegh, H, Rapoport, T.A. | | Deposit date: | 2015-11-18 | | Release date: | 2016-03-09 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (3.7 Å) | | Cite: | Crystal structure of a substrate-engaged SecY protein-translocation channel.
Nature, 531, 2016
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1RH5
 | | The structure of a protein conducting channel | | Descriptor: | Preprotein translocase secE subunit, Preprotein translocase secY subunit, SecBeta | | Authors: | van den Berg, B, Clemons Jr, W.M, Collinson, I, Modis, Y, Hartmann, E, Harrison, S.C, Rapoport, T.A. | | Deposit date: | 2003-11-13 | | Release date: | 2004-01-06 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | X-ray structure of a protein-conducting channel
Nature, 427, 2004
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1RHZ
 | | The structure of a protein conducting channel | | Descriptor: | Preprotein translocase secE subunit, Preprotein translocase secY subunit, SecBeta | | Authors: | van den Berg, B, Clemons Jr, W.M, Collinson, I, Modis, Y, Hartmann, E, Harrison, S.C, Rapoport, T.A. | | Deposit date: | 2003-11-15 | | Release date: | 2004-01-06 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | X-ray structure of a protein-conducting channel.
Nature, 427, 2004
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8B6L
 | | Subtomogram average of the human Sec61-TRAP-OSTA-translocon | | Descriptor: | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2, ... | | Authors: | Gemmer, M, Fedry, J.M.M, Forster, F.G. | | Deposit date: | 2022-09-27 | | Release date: | 2022-12-07 | | Last modified: | 2023-02-08 | | Method: | ELECTRON MICROSCOPY (7.6 Å) | | Cite: | Visualization of translation and protein biogenesis at the ER membrane.
Nature, 614, 2023
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4CG6
 | | Cryo-em of the Sec61-complex bound to the 80s ribosome translating a membrane-inserting substrate | | Descriptor: | PEPTIDE, PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT ALPHA ISOFORM 1, PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT BETA, ... | | Authors: | Gogala, M, Becker, T, Beatrix, B, Barrio-Garcia, C, Berninghausen, O, Beckmann, R. | | Deposit date: | 2013-11-21 | | Release date: | 2014-02-05 | | Last modified: | 2017-08-30 | | Method: | ELECTRON MICROSCOPY (7.8 Å) | | Cite: | Structures of the Sec61 Complex Engaged in Nascent Peptide Translocation or Membrane Insertion.
Nature, 506, 2014
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4CG7
 | | Cryo-EM of the Sec61-complex bound to the idle 80S ribosome | | Descriptor: | PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT ALPHA ISOFORM 1, PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT GAMMA, TRANSPORT PROTEIN SEC61 SUBUNIT BETA | | Authors: | Gogala, M, Becker, T, Beatrix, B, Barrio-Garcia, C, Berninghausen, O, Beckmann, R. | | Deposit date: | 2013-11-21 | | Release date: | 2014-02-05 | | Last modified: | 2017-08-30 | | Method: | ELECTRON MICROSCOPY (6.9 Å) | | Cite: | Structures of the Sec61 Complex Engaged in Nascent Peptide Translocation or Membrane Insertion.
Nature, 506, 2014
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4CG5
 | | Cryo-EM of the Sec61-complex bound to the 80S ribosome translating a secretory substrate | | Descriptor: | PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT ALPHA ISOFORM 1, PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT BETA, PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT GAMMA | | Authors: | Gogala, M, Becker, T, Beatrix, B, Barrio-Garcia, C, Berninghausen, O, Beckmann, R. | | Deposit date: | 2013-11-21 | | Release date: | 2014-02-05 | | Last modified: | 2017-08-30 | | Method: | ELECTRON MICROSCOPY (7.4 Å) | | Cite: | Structures of the Sec61 Complex Engaged in Nascent Peptide Translocation or Membrane Insertion.
Nature, 506, 2014
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7XHA
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7XHB
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5ABB
 | | Visualization of a polytopic membrane protein during SecY-mediated membrane insertion | | Descriptor: | GREEN-LIGHT ABSORBING PROTEORHODOPSIN, PROTEIN TRANSLOCASE SUBUNIT SECE, PROTEIN TRANSLOCASE SUBUNIT SECY | | Authors: | Bischoff, L, Wickles, S, Berninghausen, O, vanderSluis, E, Beckmann, R. | | Deposit date: | 2015-08-05 | | Release date: | 2015-08-19 | | Last modified: | 2017-08-30 | | Method: | ELECTRON MICROSCOPY (8 Å) | | Cite: | Visualization of a Polytopic Membrane Protein During Secy-Mediated Membrane Insertion.
Nat.Commun., 5, 2014
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5A6U
 | | Native mammalian ribosome-bound Sec61 protein-conducting channel in the 'non-inserting' state | | Descriptor: | SEC61A, SEC61B, SEC61G | | Authors: | Pfeffer, S, Burbaum, L, Unverdorben, P, Pech, M, Chen, Y, Zimmermann, R, Beckmann, R, Foerster, F. | | Deposit date: | 2015-07-01 | | Release date: | 2015-10-07 | | Last modified: | 2019-08-21 | | Method: | ELECTRON MICROSCOPY (9 Å) | | Cite: | Structure of the Native Sec61 Protein-Conducting Channel.
Nat.Commun., 6, 2015
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5AWW
 | | Precise Resting State of Thermus thermophilus SecYEG | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Protein translocase subunit SecE, Protein translocase subunit SecY, ... | | Authors: | Tanaka, Y, Sugano, Y, Takemoto, M, Kusakizako, T, Kumazaki, K, Ishitani, R, Nureki, O, Tsukazaki, T. | | Deposit date: | 2015-07-10 | | Release date: | 2015-11-25 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.724 Å) | | Cite: | Crystal Structures of SecYEG in Lipidic Cubic Phase Elucidate a Precise Resting and a Peptide-Bound State.
Cell Rep, 13, 2015
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5CH4
 | | Peptide-Bound State of Thermus thermophilus SecYEG | | Descriptor: | Protein translocase subunit SecE, Protein translocase subunit SecY, Putative preprotein translocase, ... | | Authors: | Tanaka, Y, Sugano, Y, Takemoto, M, Kusakizako, T, Kumazaki, K, Ishitani, R, Nureki, O, Tsukazaki, T. | | Deposit date: | 2015-07-10 | | Release date: | 2015-11-25 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.64 Å) | | Cite: | Crystal Structures of SecYEG in Lipidic Cubic Phase Elucidate a Precise Resting and a Peptide-Bound State.
Cell Rep, 13, 2015
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7ZL3
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3BO0
 | | Ribosome-SecY complex | | Descriptor: | 23S RIBOSOMAL RNA, PREPROTEIN TRANSLOCASE SecE SUBUNIT, PREPROTEIN TRANSLOCASE SecY SUBUNIT, ... | | Authors: | Akey, C.W, Menetret, J.F. | | Deposit date: | 2007-12-15 | | Release date: | 2008-12-09 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (9.6 Å) | | Cite: | Ribosome binding of a single copy of the SecY complex: implications for protein translocation
Mol.Cell, 28, 2007
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3BO1
 | | Ribosome-SecY complex | | Descriptor: | 23S RIBOSOMAL RNA, PREPROTEIN TRANSLOCASE SecE SUBUNIT, PREPROTEIN TRANSLOCASE SecY SUBUNIT, ... | | Authors: | Akey, C.W, Menetret, J.F. | | Deposit date: | 2007-12-15 | | Release date: | 2008-12-09 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (9.6 Å) | | Cite: | Ribosome binding of a single copy of the SecY complex: implications for protein translocation
Mol.Cell, 28, 2007
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3DL8
 | | Structure of the complex of aquifex aeolicus SecYEG and bacillus subtilis SecA | | Descriptor: | Preprotein translocase subunit secY, Protein translocase subunit secA, Protein-export membrane protein secG, ... | | Authors: | Nam, Y, Zimmer, J, Rapoport, T.A. | | Deposit date: | 2008-06-26 | | Release date: | 2008-12-02 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (7.5 Å) | | Cite: | Structure of a complex of the ATPase SecA and the protein-translocation channel.
Nature, 455, 2008
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3DIN
 | | Crystal structure of the protein-translocation complex formed by the SecY channel and the SecA ATPase | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | | Authors: | Zimmer, J, Nam, Y, Rapoport, T.A. | | Deposit date: | 2008-06-20 | | Release date: | 2008-10-07 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (4.5 Å) | | Cite: | Structure of a complex of the ATPase SecA and the protein-translocation channel.
Nature, 455, 2008
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