Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

7WZ5
DownloadVisualize
BU of 7wz5 by Molmil
Larimichthys crocea IFNi
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interferon C
Authors:Chen, J.J.
Deposit date:2022-02-17
Release date:2023-02-08
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Molecular and Structural Basis of Receptor Binding and Signaling of a Fish Type I IFN with Three Disulfide Bonds.
J Immunol., 209, 2022
7WKH
DownloadVisualize
BU of 7wkh by Molmil
the grass carp IFNa
Descriptor: Interferon
Authors:Zou, J, WANG, J, Wang, Z.
Deposit date:2022-01-09
Release date:2022-02-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Structural and Functional Analyses of Type I IFNa Shed Light Into Its Interaction With Multiple Receptors in Fish.
Front Immunol, 13, 2022
7E0E
DownloadVisualize
BU of 7e0e by Molmil
Crystal structure of mouse interferon alpha2 at 2.1 angstrom resolution
Descriptor: GLYCEROL, Interferon alpha-2, PHOSPHATE ION
Authors:Watanabe, H, Yabe-Wada, T, Unno, M.
Deposit date:2021-01-27
Release date:2021-04-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.102 Å)
Cite:Detailed structure of mouse interferon alpha 2 and its interaction with Sortilin.
J.Biochem., 170, 2021
6JHD
DownloadVisualize
BU of 6jhd by Molmil
Solution structure of IFN alpha8
Descriptor: Interferon alpha-8
Authors:Ken-ichi, A, Shigeyuki, M.
Deposit date:2019-02-18
Release date:2020-02-19
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Determination of solution structure of interferon alpha8: Novel insights into the preferred interaction with IFNAR2 among its subtypes
To Be Published
4Z5R
DownloadVisualize
BU of 4z5r by Molmil
Rontalizumab Fab bound to Interferon-a2
Descriptor: Interferon alpha-2, SULFATE ION, anti-IFN-a antibody rontalizumab heavy chain modules VH and CH1 (Fab), ...
Authors:Eigenbrot, C, Maurer, B, Bosanac, I.
Deposit date:2015-04-02
Release date:2015-07-08
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis of the broadly neutralizing anti-interferon-alpha antibody rontalizumab.
Protein Sci., 24, 2015
4YPG
DownloadVisualize
BU of 4ypg by Molmil
Structural Insights Into the Neutralization Properties of a Human Anti-Interferon Monoclonal Antibody
Descriptor: Interferon alpha-2, NICKEL (II) ION, Sifalimumab heavy chain, ...
Authors:Oganesyan, V, Dall'Acqua, W.F.
Deposit date:2015-03-12
Release date:2015-05-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Insights into the Neutralization Properties of the Fully Human, Anti-interferon Monoclonal Antibody Sifalimumab.
J.Biol.Chem., 290, 2015
3WCY
DownloadVisualize
BU of 3wcy by Molmil
Murine Ifnar1 in complex with interferon-beta
Descriptor: Interferon alpha/beta receptor 1, Interferon beta
Authors:Vivian, J.P, de Weerd, N.A, Hertzog, P.J, Rossjohn, J.
Deposit date:2013-06-04
Release date:2013-07-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of a unique interferon beta signaling axis mediated via the IFNAR1 receptor
To be Published
2LMS
DownloadVisualize
BU of 2lms by Molmil
A single GalNAc residue on Threonine-106 modifies the dynamics and the structure of Interferon alpha-2a around the glycosylation site
Descriptor: 2-acetamido-2-deoxy-alpha-D-galactopyranose, Interferon alpha-2
Authors:Ghasriani, H, Belcourt, P.J.F, Sauve, S, Hodgson, D.J, Gingras, G, Brochu, D, Gilbert, M, Aubin, Y.
Deposit date:2011-12-12
Release date:2012-12-05
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:A single N-acetylgalactosamine residue at threonine 106 modifies the dynamics and structure of interferon alpha2a around the glycosylation site.
J.Biol.Chem., 288, 2013
3UX9
DownloadVisualize
BU of 3ux9 by Molmil
Structural insights into a human anti-IFN antibody exerting therapeutic potential for systemic lupus erythematosus
Descriptor: Interferon alpha-1/13, ScFv antibody
Authors:Ouyang, S, Zhao, L.X, Liang, W, Shaw, N, Liu, Z.-J, Liang, M.-F.
Deposit date:2011-12-04
Release date:2012-02-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural insights into a human anti-IFN antibody exerting therapeutic potential for systemic lupus erythematosus
J.Mol.Med., 2012
3SE3
DownloadVisualize
BU of 3se3 by Molmil
human IFNa2-IFNAR ternary complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interferon alpha 2b, Interferon alpha/beta receptor 1, ...
Authors:Thomas, C, Garcia, K.C.
Deposit date:2011-06-10
Release date:2011-08-31
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (4.0001 Å)
Cite:Structural linkage between ligand discrimination and receptor activation by type I interferons.
Cell(Cambridge,Mass.), 146, 2011
3SE4
DownloadVisualize
BU of 3se4 by Molmil
human IFNw-IFNAR ternary complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interferon alpha/beta receptor 1, Interferon alpha/beta receptor 2, ...
Authors:Thomas, C, Garcia, K.C.
Deposit date:2011-06-10
Release date:2011-08-31
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.5001 Å)
Cite:Structural linkage between ligand discrimination and receptor activation by type I interferons.
Cell(Cambridge,Mass.), 146, 2011
3S9D
DownloadVisualize
BU of 3s9d by Molmil
binary complex between IFNa2 and IFNAR2
Descriptor: CHLORIDE ION, Interferon alpha-2, Interferon alpha/beta receptor 2
Authors:Thomas, C, Garcia, K.C.
Deposit date:2011-06-01
Release date:2011-08-31
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9999 Å)
Cite:Structural linkage between ligand discrimination and receptor activation by type I interferons.
Cell(Cambridge,Mass.), 146, 2011
2LAG
DownloadVisualize
BU of 2lag by Molmil
Structure of the 44 kDa complex of interferon-alpha2 with the extracellular part of IFNAR2 obtained by 2D-double difference NOESY
Descriptor: Interferon alpha-2, Interferon alpha/beta receptor 2
Authors:Nudelman, I, Akabayov, S.R, Scherf, T, Anglister, J.
Deposit date:2011-03-13
Release date:2011-08-17
Last modified:2011-09-28
Method:SOLUTION NMR
Cite:Observation of Intermolecular Interactions in Large Protein Complexes by 2D-Double Difference Nuclear Overhauser Enhancement Spectroscopy: Application to the 44 kDa Interferon-Receptor Complex.
J.Am.Chem.Soc., 133, 2011
3PIW
DownloadVisualize
BU of 3piw by Molmil
Zebrafish interferon 2
Descriptor: Type I interferon 2
Authors:Hamming, O.J, Hartmann, R, Lutfalla, G, Levraud, J.-P.
Deposit date:2010-11-08
Release date:2011-07-20
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.492 Å)
Cite:Crystal Structure of Zebrafish Interferons I and II Reveals Conservation of Type I Interferon Structure in Vertebrates.
J.Virol., 85, 2011
3PIV
DownloadVisualize
BU of 3piv by Molmil
Zebrafish interferon 1
Descriptor: Interferon, NICKEL (II) ION
Authors:Hamming, O.J, Hartmann, R, Lutfalla, G, Levraud, J.-P.
Deposit date:2010-11-08
Release date:2011-07-20
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.086 Å)
Cite:Crystal Structure of Zebrafish Interferons I and II Reveals Conservation of Type I Interferon Structure in Vertebrates.
J.Virol., 85, 2011
3OQ3
DownloadVisualize
BU of 3oq3 by Molmil
Structural Basis of Type-I Interferon Sequestration by a Poxvirus Decoy Receptor
Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, ...
Authors:Fremont, D.H, Lee, C.A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2010-09-02
Release date:2011-05-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis of Type-I Interferon Sequestration by a Poxvirus Decoy Receptor
To be Published
2KZ1
DownloadVisualize
BU of 2kz1 by Molmil
Inter-molecular interactions in a 44 kDa interferon-receptor complex detected by asymmetric back-protonation and 2D NOESY
Descriptor: Interferon alpha-2, Soluble IFN alpha/beta receptor
Authors:Nudelman, I, Akabayov, S.R, Schnur, E, Biron, Z, Levy, R, Xu, Y, Yang, D, Anglister, J.
Deposit date:2010-06-10
Release date:2010-06-23
Last modified:2021-08-18
Method:SOLUTION NMR
Cite:Intermolecular interactions in a 44 kDa interferon-receptor complex detected by asymmetric reverse-protonation and two-dimensional NOESY
Biochemistry, 49, 2010
2HYM
DownloadVisualize
BU of 2hym by Molmil
NMR based Docking Model of the Complex between the Human Type I Interferon Receptor and Human Interferon alpha-2
Descriptor: Interferon alpha-2, Soluble IFN alpha/beta receptor
Authors:Quadt-Akabayov, S.R, Chill, J.H, Levy, R, Kessler, N, Anglister, J.
Deposit date:2006-08-07
Release date:2006-10-10
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Determination of the human type I interferon receptor binding site on human interferon-alpha2 by cross saturation and an NMR-based model of the complex
Protein Sci., 15, 2006
1WU3
DownloadVisualize
BU of 1wu3 by Molmil
Crystal structure of recombinant murine interferon beta
Descriptor: Interferon beta
Authors:Senda, T, Saitoh, S, Mitsui, Y.
Deposit date:2004-12-01
Release date:2004-12-14
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Refined crystal structure of recombinant murine interferon-beta at 2.15 A resolution
J.Mol.Biol., 253, 1995
1B5L
DownloadVisualize
BU of 1b5l by Molmil
OVINE INTERFERON TAU
Descriptor: INTERFERON TAU, SULFATE ION
Authors:Radhakrishnan, R, Walter, L.J, Subramaniam, P.S, Johnson, H.J, Walter, M.R.
Deposit date:1999-01-07
Release date:1999-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of ovine interferon-tau at 2.1 A resolution.
J.Mol.Biol., 286, 1999
1AU1
DownloadVisualize
BU of 1au1 by Molmil
HUMAN INTERFERON-BETA CRYSTAL STRUCTURE
Descriptor: INTERFERON-BETA, ZINC ION, alpha-D-quinovopyranose-(1-6)-beta-D-glucopyranose, ...
Authors:Karpusas, M, Nolte, M, Lipscomb, W.
Deposit date:1997-09-09
Release date:1998-06-17
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The crystal structure of human interferon beta at 2.2-A resolution.
Proc.Natl.Acad.Sci.USA, 94, 1997
1ITF
DownloadVisualize
BU of 1itf by Molmil
INTERFERON ALPHA-2A, NMR, 24 STRUCTURES
Descriptor: INTERFERON ALPHA-2A
Authors:Klaus, W, Gsell, B, Labhardt, A.M, Wipf, B, Senn, H.
Deposit date:1997-08-22
Release date:1997-12-03
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:The three-dimensional high resolution structure of human interferon alpha-2a determined by heteronuclear NMR spectroscopy in solution.
J.Mol.Biol., 274, 1997
1RH2
DownloadVisualize
BU of 1rh2 by Molmil
RECOMBINANT HUMAN INTERFERON-ALPHA 2B
Descriptor: INTERFERON-ALPHA 2B, ZINC ION
Authors:Walter, M.R.
Deposit date:1996-11-07
Release date:1997-11-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Zinc mediated dimer of human interferon-alpha 2b revealed by X-ray crystallography.
Structure, 4, 1996
1IFA
DownloadVisualize
BU of 1ifa by Molmil
THREE-DIMENSIONAL CRYSTAL STRUCTURE OF RECOMBINANT MURINE INTERFERON-BETA
Descriptor: ASPARAGINE, INTERFERON-BETA
Authors:Mitsui, Y, Senda, T, Matsuda, S, Kawano, G, Nakamura, K.T, Shimizu, H.
Deposit date:1991-10-29
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Three-dimensional crystal structure of recombinant murine interferon-beta.
EMBO J., 11, 1992

217705

數據於2024-03-27公開中

PDB statisticsPDBj update infoContact PDBjnumon