Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6KVG
DownloadVisualize
BU of 6kvg by Molmil
The solution structure of human Orc6
Descriptor: Origin recognition complex subunit 6
Authors:Liu, C, Xu, N, You, Y, Zhu, G.
Deposit date:2019-09-04
Release date:2020-09-09
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural basis of DNA replication origin recognition by human Orc6 protein binding with DNA.
Nucleic Acids Res., 48, 2020
3M03
DownloadVisualize
BU of 3m03 by Molmil
Crystal structure of human Orc6 fragment
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Origin recognition complex subunit 6, SULFATE ION
Authors:Liu, S.X, Wu, L.J, Sun, J, Wang, H.F, Liu, Y.F.
Deposit date:2010-03-02
Release date:2011-03-09
Last modified:2014-03-05
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural analysis of human Orc6 protein reveals a homology with transcription factor TFIIB
Proc.Natl.Acad.Sci.USA, 108, 2011
7TJK
DownloadVisualize
BU of 7tjk by Molmil
S. cerevisiae ORC bound to 84 bp ARS1 DNA and Cdc6 (state 2) with docked Orc6 N-terminal domain
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 6, DNA, ...
Authors:Schmidt, J.M, Yang, R, Kumar, A, Hunker, O, Bleichert, F.
Deposit date:2022-01-16
Release date:2022-10-05
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6.
Nat Commun, 13, 2022
7TJJ
DownloadVisualize
BU of 7tjj by Molmil
S. cerevisiae ORC bound to 84 bp ARS1 DNA and Cdc6 (state 1) with docked Orc6 N-terminal domain
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 6, DNA, ...
Authors:Schmidt, J.M, Yang, R, Kumar, A, Hunker, O, Bleichert, F.
Deposit date:2022-01-16
Release date:2022-10-05
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6.
Nat Commun, 13, 2022
7TJH
DownloadVisualize
BU of 7tjh by Molmil
S. cerevisiae ORC bound to 84 bp ARS1 DNA and Cdc6 (state 1) with flexible Orc6 N-terminal domain
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 6, DNA, ...
Authors:Schmidt, J.M, Yang, R, Kumar, A, Hunker, O, Bleichert, F.
Deposit date:2022-01-16
Release date:2022-10-05
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6.
Nat Commun, 13, 2022
7TJI
DownloadVisualize
BU of 7tji by Molmil
S. cerevisiae ORC bound to 84 bp ARS1 DNA and Cdc6 (state 2) with flexible Orc6 N-terminal domain
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 6, DNA, ...
Authors:Schmidt, J.M, Yang, R, Kumar, A, Hunker, O, Bleichert, F.
Deposit date:2022-01-16
Release date:2022-10-05
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6.
Nat Commun, 13, 2022
7TJF
DownloadVisualize
BU of 7tjf by Molmil
S. cerevisiae ORC bound to 84 bp ARS1 DNA
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA, 84 bp ARS1, ...
Authors:Schmidt, J.M, Yang, R, Kumar, A, Hunker, O, Bleichert, F.
Deposit date:2022-01-16
Release date:2023-01-18
Last modified:2023-02-22
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:A mechanism of origin licensing control through autoinhibition of S. cerevisiae ORC·DNA·Cdc6.
Nat Commun, 13, 2022
4XGC
DownloadVisualize
BU of 4xgc by Molmil
Crystal structure of the eukaryotic origin recognition complex
Descriptor: CHLORIDE ION, Origin recognition complex subunit 1, Origin recognition complex subunit 2, ...
Authors:Bleichert, F, Botchan, M.R, Berger, J.M.
Deposit date:2014-12-30
Release date:2015-04-01
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structure of the eukaryotic origin recognition complex.
Nature, 519, 2015
7MCA
DownloadVisualize
BU of 7mca by Molmil
Structure of the S. cerevisiae origin recognition complex bound to the replication initiator Cdc6 and the ARS1 origin DNA.
Descriptor: Cell division control protein 6, DNA (85-MER), MAGNESIUM ION, ...
Authors:Feng, X, Li, H.
Deposit date:2021-04-01
Release date:2021-06-02
Last modified:2021-08-04
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:The structure of ORC-Cdc6 on an origin DNA reveals the mechanism of ORC activation by the replication initiator Cdc6.
Nat Commun, 12, 2021
5V8F
DownloadVisualize
BU of 5v8f by Molmil
Structural basis of MCM2-7 replicative helicase loading by ORC-Cdc6 and Cdt1
Descriptor: Cell division control protein 6, Cell division cycle protein CDT1, DNA (39-MER), ...
Authors:Yuan, Z, Riera, A, Bai, L, Sun, J, Spanos, C, Chen, Z.A, Barbon, M, Rappsilber, J, Stillman, B, Speck, C, Li, H.
Deposit date:2017-03-21
Release date:2017-05-10
Last modified:2020-04-22
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis of Mcm2-7 replicative helicase loading by ORC-Cdc6 and Cdt1.
Nat. Struct. Mol. Biol., 24, 2017
6RQC
DownloadVisualize
BU of 6rqc by Molmil
Cryo-EM structure of an MCM loading intermediate
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (88-MER), ...
Authors:Miller, T.C.R, Locke, J, Costa, A.
Deposit date:2019-05-15
Release date:2019-11-20
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Mechanism of head-to-head MCM double-hexamer formation revealed by cryo-EM.
Nature, 575, 2019
5ZR1
DownloadVisualize
BU of 5zr1 by Molmil
Saccharomyces Cerevisiae Origin Recognition Complex Bound to a 72-bp Origin DNA containing ACS and B1 element
Descriptor: 72bp-oring DNA, ACS305, A-rich, ...
Authors:Li, N, Lam, W.H, Zhai, Y, Cheng, J, Cheng, E, Zhao, Y, Gao, N, Tye, B.K.
Deposit date:2018-04-21
Release date:2018-07-11
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure of the origin recognition complex bound to DNA replication origin.
Nature, 559, 2018
6WGI
DownloadVisualize
BU of 6wgi by Molmil
Atomic model of the mutant OCCM (ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation) loaded on DNA at 10.5 A resolution
Descriptor: Cell division control protein 6, Cell division cycle protein CDT1, DNA (34-MER), ...
Authors:Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C.
Deposit date:2020-04-05
Release date:2020-07-15
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6.
Proc.Natl.Acad.Sci.USA, 117, 2020
6WGG
DownloadVisualize
BU of 6wgg by Molmil
Atomic model of pre-insertion mutant OCCM-DNA complex(ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation)
Descriptor: Cell division control protein 6, Cell division cycle protein CDT1, DNA (41-MER), ...
Authors:Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C.
Deposit date:2020-04-05
Release date:2020-07-15
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (8.1 Å)
Cite:Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6.
Proc.Natl.Acad.Sci.USA, 117, 2020
6WGC
DownloadVisualize
BU of 6wgc by Molmil
Atomic model of semi-attached mutant OCCM-DNA complex (ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation)
Descriptor: Cell division control protein 6, DNA (41-MER), DNA replication licensing factor MCM3, ...
Authors:Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C.
Deposit date:2020-04-05
Release date:2020-07-15
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6.
Proc.Natl.Acad.Sci.USA, 117, 2020
7JK4
DownloadVisualize
BU of 7jk4 by Molmil
Structure of Drosophila ORC bound to AT-rich DNA and Cdc6
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein, DNA (34-MER), ...
Authors:Schmidt, J.M, Bleichert, F.
Deposit date:2020-07-27
Release date:2020-09-09
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6.
Nat Commun, 11, 2020
7JK6
DownloadVisualize
BU of 7jk6 by Molmil
Structure of Drosophila ORC in the active conformation
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Origin recognition complex subunit 1, ...
Authors:Schmidt, J.M, Bleichert, F.
Deposit date:2020-07-27
Release date:2020-09-09
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6.
Nat Commun, 11, 2020
7JK2
DownloadVisualize
BU of 7jk2 by Molmil
Structure of Drosophila ORC bound to poly(dA/dT) DNA and Cdc6 (conformation 1)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein, DNA (33-MER), ...
Authors:Schmidt, J.M, Bleichert, F.
Deposit date:2020-07-27
Release date:2020-09-09
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6.
Nat Commun, 11, 2020
7JK3
DownloadVisualize
BU of 7jk3 by Molmil
Structure of Drosophila ORC bound to GC-rich DNA and Cdc6
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein, DNA (33-MER), ...
Authors:Schmidt, J.M, Bleichert, F.
Deposit date:2020-07-27
Release date:2020-09-09
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6.
Nat Commun, 11, 2020
7JK5
DownloadVisualize
BU of 7jk5 by Molmil
Structure of Drosophila ORC bound to DNA
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA (32-MER), MAGNESIUM ION, ...
Authors:Schmidt, J.M, Bleichert, F.
Deposit date:2020-07-27
Release date:2020-09-09
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6.
Nat Commun, 11, 2020
7JGS
DownloadVisualize
BU of 7jgs by Molmil
Structure of Drosophila ORC bound to poly(dA/dT) DNA and Cdc6 (conformation 2)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, AT22044p1, Cell division control protein, ...
Authors:Schmidt, J.M, Bleichert, F.
Deposit date:2020-07-19
Release date:2020-09-09
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6.
Nat Commun, 11, 2020
7JGR
DownloadVisualize
BU of 7jgr by Molmil
Structure of Drosophila ORC bound to DNA (84 bp) and Cdc6
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, AT22044p1, Cell division control protein, ...
Authors:Schmidt, J.M, Bleichert, F.
Deposit date:2020-07-19
Release date:2020-09-09
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6.
Nat Commun, 11, 2020
2LE8
DownloadVisualize
BU of 2le8 by Molmil
The protein complex for DNA replication
Descriptor: DNA replication factor Cdt1, DNA replication licensing factor MCM6
Authors:Liu, C, Wei, Z, Zhu, G.
Deposit date:2011-06-14
Release date:2012-12-19
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural insights into the Cdt1-mediated MCM2-7 chromatin loading
Nucleic Acids Res., 40, 2012

217705

數據於2024-03-27公開中

PDB statisticsPDBj update infoContact PDBjnumon