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6MK5	Solution NMR structure of spider toxin analogue [F5A,M6F,T26L,K28R]GpTx-1 Descriptor: Toxin GTx1-15 Authors: Schroeder, C.I. Deposit date: 2018-09-25 Release date: 2018-12-19 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Peptide-Membrane Interactions Affect the Inhibitory Potency and Selectivity of Spider Toxins ProTx-II and GpTx-1. ACS Chem. Biol., 14, 2019
1D1H	SOLUTION STRUCTURE OF HANATOXIN 1 Descriptor: HANATOXIN TYPE 1 Authors: Takahashi, H, Kim, J.I, Sato, K, Swartz, K.J, Shimada, I. Deposit date: 1999-09-16 Release date: 2000-09-20 Last modified: 2022-02-16 Method: SOLUTION NMR Cite: Solution structure of hanatoxin1, a gating modifier of voltage-dependent K(+) channels: common surface features of gating modifier toxins. J.Mol.Biol., 297, 2000
1EMX	SOLUTION STRUCTURE OF HPTX2, A TOXIN FROM HETEROPODA VENATORIA SPIDER VENOM THAT BLOCKS KV4.2 POTASSIUM CHANNEL Descriptor: HETEROPODATOXIN 2 Authors: Bernard, C, Legros, C, Ferrat, G, Bishoff, U, Marquardt, A, Pongs, O, Darbon, H. Deposit date: 2000-03-20 Release date: 2001-01-24 Last modified: 2022-02-16 Method: SOLUTION NMR Cite: Solution structure of hpTX2, a toxin from Heteropoda venatoria spider that blocks Kv4.2 potassium channel. Protein Sci., 9, 2000
2WH9	Solution structure of GxTX-1E Descriptor: GUANGXITOXIN-1EGXTX-1E Authors: Lee, S.K, Jung, H.H, Lee, J.Y, Lee, C.W, Kim, J.I. Deposit date: 2009-05-02 Release date: 2010-05-26 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Solution Structure of Gxtx-1E, a High Affinity Tarantula Toxin Interacting with Voltage Sensors in Kv2.1 Potassium Channels. Biochemistry, 49, 2010
5EPM	Ceratotoxin variant in complex with specific antibody Fab fragment Descriptor: Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, Beta-theraphotoxin-Cm1a Authors: Strop, P, Shcherbatko, A, Rossi, A. Deposit date: 2015-11-11 Release date: 2016-05-04 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Engineering Highly Potent and Selective Microproteins against Nav1.7 Sodium Channel for Treatment of Pain. J.Biol.Chem., 291, 2016
8FD4	Solution structure of mu-theraphotoxin Cg4a from Chinese tarantula Chilobrachys jingzhao Descriptor: Jingzhaotoxin F7-10.36 Authors: Sharma, G, Jia, X, Chin, Y.K.Y, Mobli, M. Deposit date: 2022-12-01 Release date: 2023-11-08 Method: SOLUTION NMR Cite: Solution structure of mu-theraphotoxin Cg4a from Chinese tarantula Chilobrachys jingzhao To Be Published
6GFT	Antinociceptive evaluation of cyriotoxin-1a, the first toxin purified from Cyriopagopus schioedtei spider venom Descriptor: cyriotoxin-1a Authors: Kurz, M. Deposit date: 2018-05-02 Release date: 2019-03-06 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: From identification to functional characterization of cyriotoxin-1a, an antinociceptive toxin from the spider Cyriopagopus schioedtei. Br.J.Pharmacol., 176, 2019
2AAP	Solution structure of jingzhaotoxin-vii Descriptor: Jingzhaotoxin-Vii Authors: Liao, Z, Liang, S.P. Deposit date: 2005-07-14 Release date: 2005-08-02 Last modified: 2022-03-09 Method: SOLUTION NMR Cite: Solution structure of jingzhaotoxin-vii TO BE PUBLISHED
2A2V	The solution structure of Jingzhaotoxin-XI Descriptor: Jingzhaotoxin-XI Authors: Liao, Z, Liang, S.P. Deposit date: 2005-06-23 Release date: 2005-07-05 Last modified: 2022-03-09 Method: SOLUTION NMR Cite: The solution structure of Jingzhaotoxin-XI To be published
5I1X	Resonance assignments and NMR structure determination of tarantula toxin, F8A mutant of beta-TRTX-Pre1a Descriptor: mu-TRTX-Pre1a toxin Authors: Chin, Y.K.-Y, Wingerd, J.S, Mobli, M, Rash, L.D. Deposit date: 2016-02-07 Release date: 2017-02-08 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Resonance assignments and NMR structure determination of tarantula toxin, mu-TRTX-Pre1a To Be Published
5I2P	Resonance assignments and NMR structure determination of tarantula toxin- W7A mutant of mu-TRTX-Pre1a (W6A in native sequence numbering) Descriptor: W7A mu-TRTX-Pre1a Toxin Authors: Chin, Y.K.-Y, Wingerd, J.S, Mobli, M, Rash, L.D. Deposit date: 2016-02-09 Release date: 2017-06-28 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Resonance assignments and NMR structure determination of tarantula toxin- W7A mutant of mu-TRTX-Pre1a To Be Published
6V6T	Solution structure of delta-theraphotoxin-Hm1b from Heteroscodra maculata Descriptor: Delta-theraphotoxin-Hm1b Authors: Chin, Y.K.Y, Chow, C.Y, King, G.F. Deposit date: 2019-12-05 Release date: 2020-05-13 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: A selective Na V 1.1 activator with potential for treatment of Dravet syndrome epilepsy. Biochem Pharmacol, 181, 2020
1TYK	SOLUTION STRUCTURE OF A TOXIN FROM THE TARANTULA, GRAMMOSTOLA SPATULATA, WHICH INHIBITS MECHANOSENSITIVE ION CHANNELS Descriptor: Toxin GsMTx-4 Authors: Oswald, R.E, Suchyna, T.M, Mcfeeters, R, Gottlieb, P, Sachs, F. Deposit date: 2004-07-08 Release date: 2004-07-13 Last modified: 2022-03-02 Method: SOLUTION NMR Cite: Solution Structure of Peptide Toxins that Block Mechanosensitive Ion Channels J.Biol.Chem., 277, 2002
1V7F	Solution structure of phrixotoxin 1 Descriptor: Phrixotoxin 1 Authors: Chagot, B, Escoubas, P, Villegas, E, Bernard, C, Ferrat, G, Corzo, G, Lazdunski, M, Darbon, H. Deposit date: 2003-12-16 Release date: 2004-11-23 Last modified: 2023-12-27 Method: SOLUTION NMR Cite: Solution structure of Phrixotoxin 1, a specific peptide inhibitor of Kv4 potassium channels from the venom of the theraphosid spider Phrixotrichus auratus Protein Sci., 13, 2004
6AV8	Exploring Cystine Dense Peptide Space to Open a Unique Molecular Toolbox Descriptor: U5-theraphotoxin-Hs1b 1 Authors: Gewe, M.M, Rupert, P, Strong, R.K. Deposit date: 2017-09-01 Release date: 2018-02-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Screening, large-scale production and structure-based classification of cystine-dense peptides. Nat. Struct. Mol. Biol., 25, 2018
6BTV	Solution NMR structures for CcoTx-II Descriptor: Beta-theraphotoxin-Cm1b Authors: Agwa, A.J, Schroeder, C.I. Deposit date: 2017-12-07 Release date: 2018-05-09 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Gating modifier toxins isolated from spider venom: Modulation of voltage-gated sodium channels and the role of lipid membranes. J. Biol. Chem., 293, 2018
6BR0	Solution NMR structure for CcoTx-I Descriptor: Beta-theraphotoxin-Cm1a Authors: Agwa, A.J, Schroeder, C.I. Deposit date: 2017-11-29 Release date: 2018-05-16 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Gating modifier toxins isolated from spider venom: Modulation of voltage-gated sodium channels and the role of lipid membranes. J. Biol. Chem., 293, 2018
1ZJQ	Solution structure of Jingzhaotoxin-VII Descriptor: Jingzhaotoxin-VII Authors: Liao, Z. Deposit date: 2005-04-30 Release date: 2005-05-24 Last modified: 2022-03-02 Method: SOLUTION NMR Cite: Solution structure of Jingzhaotoxin-VII TO BE PUBLISHED
2MXM	NMR solution structure of TRTX-Tp1a from the tarantula Thrixopelma pruriens Descriptor: entity Authors: Rosengren, K. Deposit date: 2015-01-08 Release date: 2015-06-03 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Identification and Characterization of ProTx-III [ mu-TRTX-Tp1a], a New Voltage-Gated Sodium Channel Inhibitor from Venom of the Tarantula Thrixopelma pruriens. Mol.Pharmacol., 88, 2015
2N6O	Structure of spider-venom peptide Hm1a Descriptor: Kappa-theraphotoxin-Hm1a Authors: Undheim, E.A.B, King, G.F, Mobli, M. Deposit date: 2015-08-27 Release date: 2016-09-07 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Structure of spider-venom peptide Hm1a To be Published
5TLR	Solution NMR structure of gHwTx-IV Descriptor: Mu-theraphotoxin-Hs2a Authors: Agwa, A.J, Schroeder, C.I. Deposit date: 2016-10-11 Release date: 2017-02-22 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNaV1.7. Biochim. Biophys. Acta, 1859, 2017
5T3M	Solution structure of a triple mutant of HwTx-IV - a potent blocker of Nav1.7 Descriptor: Mu-theraphotoxin-Hs2a Authors: Rahnama, S, Sharma, G, Mobli, M. Deposit date: 2016-08-25 Release date: 2017-09-06 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: The structure, dynamics and selectivity profile of a NaV1.7 potency-optimised huwentoxin-IV variant. PLoS ONE, 12, 2017
2MQF	NMR structure of spider toxin-TRTX-Hhn2b Descriptor: Mu-theraphotoxin-Hhn2b Authors: Klint, J.K, Chin, Y.K.Y, Mobli, M. Deposit date: 2014-06-19 Release date: 2015-07-15 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Rational Engineering Defines a Molecular Switch That Is Essential for Activity of Spider-Venom Peptides against the Analgesics Target NaV1.7 Mol.Pharmacol., 88, 2015
2MXO	NMR structure of spider toxin- G7W/N24S mutant of TRTX-Hhn2b Descriptor: Mu-theraphotoxin-Hhn2b Authors: Klint, J.K, Chin, Y.K.Y, Mobli, M. Deposit date: 2015-01-08 Release date: 2015-12-23 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Rational Engineering Defines a Molecular Switch That Is Essential for Activity of Spider-Venom Peptides against the Analgesics Target NaV1.7 Mol.Pharmacol., 88, 2015
5WLX	Solution structure of kappa-theraphotoxin-Aa1a Descriptor: Kappa-theraphotoxin-Aa1a Authors: Chin, Y.K.Y, Ma, L, King, G.F. Deposit date: 2017-07-28 Release date: 2018-08-01 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Novel venom-derived inhibitors of the human EAG channel, a putative antiepileptic drug target. Biochem. Pharmacol., 158, 2018

 

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