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1LR7
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BU of 1lr7 by Molmil
Crystal structure of Fs1, the heparin-binding domain of follistatin, complexed with the heparin analogue sucrose octasulphate (SOS)
Descriptor: SULFATE ION, follistatin
Authors:Innis, C.A, Hyvonen, M.
Deposit date:2002-05-15
Release date:2003-07-29
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal Structures of the Heparan Sulfate-binding Domain of Follistatin: Insights into ligand binding.
J.Biol.Chem., 278, 2003
1YU6
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BU of 1yu6 by Molmil
Crystal Structure of the Subtilisin Carlsberg:OMTKY3 Complex
Descriptor: CALCIUM ION, Ovomucoid, Subtilisin Carlsberg
Authors:Maynes, J.T, Cherney, M.M, Qasim, M.A, Laskowski Jr, M, James, M.N.G.
Deposit date:2005-02-11
Release date:2005-05-03
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure of the subtilisin Carlsberg-OMTKY3 complex reveals two different ovomucoid conformations.
Acta Crystallogr.,Sect.D, 61, 2005
1Z7K
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BU of 1z7k by Molmil
Crystal Structure of Trypsin- Ovomucoid turkey egg white inhibitor complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ovomucoid, Trypsin
Authors:Syed Ibrahim, B, Pattabhi, V.
Deposit date:2005-03-25
Release date:2005-04-05
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of trypsin-turkey egg white inhibitor complex
Biochem.Biophys.Res.Commun., 313, 2004
2ARP
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BU of 2arp by Molmil
Activin A in complex with Fs12 fragment of follistatin
Descriptor: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, Follistatin, GLYCEROL, ...
Authors:Harrington, A.E, Morris-Triggs, S.A, Ruotolo, B.T, Robinson, C.V, Ohnuma, S, Hyvonen, M.
Deposit date:2005-08-21
Release date:2006-03-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the inhibition of activin signalling by follistatin
Embo J., 25, 2006
3PIS
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BU of 3pis by Molmil
Crystal Structure of Carcinoscorpius rotundicauda Serine Protease Inhibitor Domain 1
Descriptor: Kazal-type serine protease inhibitor SPI-1
Authors:Giri, P.K, Tang, X.H, Sivaraman, J.
Deposit date:2010-11-08
Release date:2010-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Modifying the Substrate Specificity of Carcinoscorpius rotundicauda Serine Protease Inhibitor Domain 1 to Target Thrombin
To be Published
3TJQ
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BU of 3tjq by Molmil
N-domain of HtrA1
Descriptor: CHLORIDE ION, GLYCEROL, PLATINUM (II) ION, ...
Authors:Eigenbrot, C, Ultsch, M.
Deposit date:2011-08-24
Release date:2012-05-16
Last modified:2012-06-27
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Structural and Functional Analysis of HtrA1 and Its Subdomains.
Structure, 20, 2012
1LR8
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BU of 1lr8 by Molmil
Crystal structure of Fs1, the heparin-binding domain of follistatin, complexed with the heparin analogue D-myo-inositol hexasulphate (Ins6S)
Descriptor: D-MYO-INOSITOL-HEXASULPHATE, Follistatin
Authors:Innis, C.A, Hyvonen, M.
Deposit date:2002-05-15
Release date:2003-07-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures of the Heparan Sulfate-binding Domain of Follistatin: Insights into ligand binding.
J.Biol.Chem., 278, 2003
3HH2
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BU of 3hh2 by Molmil
Crystal structure of the myostatin:follistatin 288 complex
Descriptor: CITRIC ACID, Follistatin, Growth/differentiation factor 8, ...
Authors:Cash, J.N, Thompson, T.B.
Deposit date:2009-05-14
Release date:2009-08-04
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The structure of myostatin:follistatin 288: insights into receptor utilization and heparin binding
Embo J., 28, 2009
7KBU
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BU of 7kbu by Molmil
Structure of Hevin FS-EC
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
Authors:Machius, M, Fan, S, Rudenko, G.
Deposit date:2020-10-03
Release date:2021-02-10
Last modified:2021-07-14
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Interplay between hevin, SPARC, and MDGAs: Modulators of neurexin-neuroligin transsynaptic bridges.
Structure, 29, 2021
7Q6C
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BU of 7q6c by Molmil
complement C6 FIM1-2 bound to CP010 antibody
Descriptor: ACETATE ION, CP010 heavy chain, CP010 light chain, ...
Authors:Olesen, H.G, Andersen, G.R.
Deposit date:2021-11-06
Release date:2022-05-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.29274 Å)
Cite:Development, Characterization, and in vivo Validation of a Humanized C6 Monoclonal Antibody that Inhibits the Membrane Attack Complex.
J Innate Immun, 2022
6JZA
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BU of 6jza by Molmil
Structure of Fstl1
Descriptor: Follistatin-related protein 1
Authors:Liu, X, Ning, W.
Deposit date:2019-04-30
Release date:2019-08-21
Last modified:2019-09-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and functional study of FK domain of Fstl1.
Protein Sci., 28, 2019
5JHW
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BU of 5jhw by Molmil
Crystal Structure of the GDF11:Follistatin 288 complex
Descriptor: CITRATE ANION, Follistatin, Growth/differentiation factor 11, ...
Authors:Walker, R.G, Thompson, T.B.
Deposit date:2016-04-21
Release date:2017-03-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural basis for potency differences between GDF8 and GDF11.
BMC Biol., 15, 2017
3SEK
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BU of 3sek by Molmil
Crystal Structure of the Myostatin:Follistatin-like 3 Complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Follistatin-related protein 3, Growth/differentiation factor 8
Authors:Cash, J.N, Thompson, T.B.
Deposit date:2011-06-10
Release date:2011-11-02
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.401 Å)
Cite:Structure of myostatinfollistatin-like 3: N-terminal domains of follistatin-type molecules exhibit alternate modes of binding.
J.Biol.Chem., 287, 2012
3B4V
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BU of 3b4v by Molmil
X-Ray structure of Activin in complex with FSTL3
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Inhibin beta A chain, ...
Authors:Thompson, T.B.
Deposit date:2007-10-24
Release date:2008-09-02
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:The structure of FSTL3.activin A complex. Differential binding of N-terminal domains influences follistatin-type antagonist specificity.
J.Biol.Chem., 283, 2008
1LR9
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BU of 1lr9 by Molmil
STRUCTURE OF Fs1, THE HEPARIN-BINDING DOMAIN OF FOLLISTATIN
Descriptor: Follistatin
Authors:Innis, C.A, Hyvonen, M.
Deposit date:2002-05-15
Release date:2003-07-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structures of the Heparan Sulfate-binding Domain of Follistatin: Insights into ligand binding.
J.Biol.Chem., 278, 2003
1TBR
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BU of 1tbr by Molmil
CRYSTAL STRUCTURE OF INSECT DERIVED DOUBLE DOMAIN KAZAL INHIBITOR RHODNIIN IN COMPLEX WITH THROMBIN
Descriptor: RHODNIIN, THROMBIN
Authors:Van De Locht, A, Lamba, D, Bode, W.
Deposit date:1995-03-03
Release date:1996-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Two heads are better than one: crystal structure of the insect derived double domain Kazal inhibitor rhodniin in complex with thrombin.
EMBO J., 14, 1995
3QTL
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BU of 3qtl by Molmil
Structural Basis for Dual-inhibition Mechanism of a Non-classical Kazal-type Serine Protease Inhibitor from Horseshoe Crab in Complex with Subtilisin
Descriptor: Kazal-type serine protease inhibitor SPI-1, Subtilisin-like serin protease
Authors:Shenoy, R.T, Sivaraman, J.
Deposit date:2011-02-23
Release date:2011-06-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for dual-inhibition mechanism of a non-classical kazal-type serine protease inhibitor from horseshoe crab in complex with subtilisin.
Plos One, 6, 2011
2B0U
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BU of 2b0u by Molmil
The Structure of the Follistatin:Activin Complex
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Follistatin, IRIDIUM (III) ION, ...
Authors:Thompson, T.B, Lerch, T.F, Cook, R.W, Woodruff, T.K, Jardetzky, T.S.
Deposit date:2005-09-14
Release date:2005-10-11
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Structure of the Follistatin:Activin Complex Reveals Antagonism of Both Type I and Type II Receptor Binding.
Dev.Cell, 9, 2005
3T5O
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BU of 3t5o by Molmil
Crystal Structure of human Complement Component C6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, Complement component C6, ...
Authors:Aleshin, A.E, Stec, B, Bankston, L.A, DiScipio, R.G, Liddington, R.C.
Deposit date:2011-07-27
Release date:2012-02-01
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.869 Å)
Cite:Structure of Complement C6 Suggests a Mechanism for Initiation and Unidirectional, Sequential Assembly of Membrane Attack Complex (MAC).
J.Biol.Chem., 287, 2012
7EEB
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BU of 7eeb by Molmil
Structure of the CatSpermasome
Descriptor: (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Wu, J.P, Ke, M.
Deposit date:2021-03-18
Release date:2021-07-28
Last modified:2021-08-11
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure of a mammalian sperm cation channel complex.
Nature, 595, 2021
8K6L
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BU of 8k6l by Molmil
Cryo-EM structure of human OATP1B1 in complex with DCF
Descriptor: 2',7'-bis(chloranyl)-3',6'-bis(oxidanyl)spiro[2-benzofuran-3,9'-xanthene]-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Shan, Z, Yang, X, Zhang, Y.
Deposit date:2023-07-25
Release date:2023-09-13
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (2.92 Å)
Cite:Cryo-EM structures of human organic anion transporting polypeptide OATP1B1.
Cell Res., 33, 2023
8PG0
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BU of 8pg0 by Molmil
Human OATP1B3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, BICARBONATE ION, CHOLESTEROL, ...
Authors:Ciuta, A.-D, Nosol, K, Kowal, J, Mukherjee, S, Ramirez, A.S, Stieger, B, Kossiakoff, A.A, Locher, K.P.
Deposit date:2023-06-17
Release date:2023-09-27
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Structure of human drug transporters OATP1B1 and OATP1B3.
Nat Commun, 14, 2023
8B0F
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BU of 8b0f by Molmil
CryoEM structure of C5b8-CD59
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Bubeck, D, Couves, E.C, Gardner, S.
Deposit date:2022-09-07
Release date:2023-02-22
Last modified:2023-03-01
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis for membrane attack complex inhibition by CD59.
Nat Commun, 14, 2023
1TBQ
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BU of 1tbq by Molmil
CRYSTAL STRUCTURE OF INSECT DERIVED DOUBLE DOMAIN KAZAL INHIBITOR RHODNIIN IN COMPLEX WITH THROMBIN
Descriptor: RHODNIIN, THROMBIN
Authors:Van De Locht, A, Lamba, D, Bode, W.
Deposit date:1995-03-02
Release date:1996-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Two heads are better than one: crystal structure of the insect derived double domain Kazal inhibitor rhodniin in complex with thrombin.
EMBO J., 14, 1995
8HND
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BU of 8hnd by Molmil
Cryo-EM structure of human OATP1B1 in complex with estrone-3-sulfate
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Solute carrier organic anion transporter family member 1B1, ...
Authors:Shan, Z, Yang, X, Liu, H, Nan, J, Yuan, Y, Zhang, Y.
Deposit date:2022-12-07
Release date:2023-09-13
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Cryo-EM structures of human organic anion transporting polypeptide OATP1B1.
Cell Res., 33, 2023

 

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