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1X3A
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BU of 1x3a by Molmil
Solution structure of the BSD domain of human Synapse associated protein 1
Descriptor: Synapse associated protein 1
Authors:Yoneyama, M, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-02
Release date:2005-11-02
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution structure of the BSD domain of human Synapse associated protein 1
To be Published
7AD8
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BU of 7ad8 by Molmil
Core TFIIH-XPA-DNA complex with modelled p62 subunit
Descriptor: DNA (49-MER), DNA repair protein complementing XP-A cells, General transcription and DNA repair factor IIH helicase subunit XPB, ...
Authors:Koelmel, W, Kuper, J, Kisker, C.
Deposit date:2020-09-14
Release date:2021-07-28
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:The TFIIH subunits p44/p62 act as a damage sensor during nucleotide excision repair.
Nucleic Acids Res., 48, 2020
6GYM
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BU of 6gym by Molmil
Structure of a yeast closed complex with distorted DNA (CCdist)
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Dienemann, C, Schwalb, B, Schilbach, S, Cramer, P.
Deposit date:2018-06-30
Release date:2018-12-05
Last modified:2019-12-25
Method:ELECTRON MICROSCOPY (6.7 Å)
Cite:Promoter Distortion and Opening in the RNA Polymerase II Cleft.
Mol. Cell, 73, 2019
5OQM
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BU of 5oqm by Molmil
STRUCTURE OF YEAST TRANSCRIPTION PRE-INITIATION COMPLEX WITH TFIIH AND CORE MEDIATOR
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Schilbach, S, Hantsche, M, Tegunov, D, Dienemann, C, Wigge, C, Urlaub, H, Cramer, P.
Deposit date:2017-08-13
Release date:2018-05-09
Last modified:2018-11-21
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Structures of transcription pre-initiation complex with TFIIH and Mediator.
Nature, 551, 2017
5OQJ
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BU of 5oqj by Molmil
STRUCTURE OF YEAST TRANSCRIPTION PRE-INITIATION COMPLEX WITH TFIIH
Descriptor: DNA repair helicase RAD25, DNA repair helicase RAD3, DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Schilbach, S, Hantsche, M, Tegunov, D, Dienemann, C, Wigge, C, Henning, U, Cramer, P.
Deposit date:2017-08-11
Release date:2018-04-25
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Structures of transcription pre-initiation complex with TFIIH and Mediator.
Nature, 551, 2017
7ZSA
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BU of 7zsa by Molmil
Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome and NTP (complex B)
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Wang, H, Cramer, P.
Deposit date:2022-05-06
Release date:2022-11-16
Last modified:2023-03-01
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structures of transcription preinitiation complex engaged with the +1 nucleosome.
Nat.Struct.Mol.Biol., 30, 2023
7ZSB
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BU of 7zsb by Molmil
Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome and NTP, complex C
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Wang, H, Cramer, P.
Deposit date:2022-05-06
Release date:2022-11-16
Last modified:2023-03-01
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Structures of transcription preinitiation complex engaged with the +1 nucleosome.
Nat.Struct.Mol.Biol., 30, 2023
7ZS9
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BU of 7zs9 by Molmil
Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome (complex A)
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Wang, H, Cramer, P.
Deposit date:2022-05-06
Release date:2022-11-16
Last modified:2023-03-01
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structures of transcription preinitiation complex engaged with the +1 nucleosome.
Nat.Struct.Mol.Biol., 30, 2023
8BVW
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BU of 8bvw by Molmil
RNA polymerase II pre-initiation complex with the distal +1 nucleosome (PIC-Nuc18W)
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P.
Deposit date:2022-12-20
Release date:2023-05-03
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.
Mol.Cell, 83, 2023
8BYQ
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BU of 8byq by Molmil
RNA polymerase II pre-initiation complex with the proximal +1 nucleosome (PIC-Nuc10W)
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P.
Deposit date:2022-12-14
Release date:2023-05-03
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.
Mol.Cell, 83, 2023
8CEO
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BU of 8ceo by Molmil
Yeast RNA polymerase II transcription pre-initiation complex with core Mediator and the +1 nucleosome
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Wang, H, Cramer, P.
Deposit date:2023-02-02
Release date:2023-03-08
Last modified:2023-04-19
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Yeast PIC-Mediator structure with RNA polymerase II C-terminal domain.
Proc.Natl.Acad.Sci.USA, 120, 2023
6NMI
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BU of 6nmi by Molmil
Cryo-EM structure of the human TFIIH core complex
Descriptor: CDK-activating kinase assembly factor MAT1, General transcription and DNA repair factor IIH helicase subunit XPB, General transcription and DNA repair factor IIH helicase subunit XPD, ...
Authors:Greber, B.J, Toso, D, Fang, J, Nogales, E.
Deposit date:2019-01-10
Release date:2019-03-13
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:The complete structure of the human TFIIH core complex.
Elife, 8, 2019
6O9M
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BU of 6o9m by Molmil
Structure of the human apo TFIIH
Descriptor: CDK-activating kinase assembly factor MAT1, General transcription factor IIH subunit 1, General transcription factor IIH subunit 2, ...
Authors:Yan, C.L, Dodd, T, He, Y, Tainer, J.A, Tsutakawa, S.E, Ivanov, I.
Deposit date:2019-03-14
Release date:2019-05-29
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Transcription preinitiation complex structure and dynamics provide insight into genetic diseases.
Nat.Struct.Mol.Biol., 26, 2019
6O9L
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BU of 6o9l by Molmil
Human holo-PIC in the closed state
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Yan, C.L, Dodd, T, He, Y, Tainer, J.A, Tsutakawa, S.E, Ivanov, I.
Deposit date:2019-03-14
Release date:2019-05-29
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (7.2 Å)
Cite:Transcription preinitiation complex structure and dynamics provide insight into genetic diseases.
Nat.Struct.Mol.Biol., 26, 2019
7EGB
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BU of 7egb by Molmil
TFIID-based holo PIC on SCP promoter
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-05
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7EGC
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BU of 7egc by Molmil
p53-bound TFIID-based holo PIC on HDM2 promoter
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y.
Deposit date:2021-03-24
Release date:2021-05-12
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
7ENA
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BU of 7ena by Molmil
TFIID-based PIC-Mediator holo-complex in pre-assembled state (pre-hPIC-MED)
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Chen, X, Qi, Y, Wang, X, Wu, Z, Yin, X, Li, J, Liu, W, Xu, Y.
Deposit date:2021-04-16
Release date:2021-05-26
Last modified:2021-06-16
Method:ELECTRON MICROSCOPY (4.07 Å)
Cite:Structures of the human Mediator and Mediator-bound preinitiation complex.
Science, 372, 2021
7ENC
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BU of 7enc by Molmil
TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED)
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Chen, X, Qi, Y, Wang, X, Wu, Z, Yin, X, Li, J, Liu, W, Xu, Y.
Deposit date:2021-04-16
Release date:2021-05-26
Last modified:2021-06-16
Method:ELECTRON MICROSCOPY (4.13 Å)
Cite:Structures of the human Mediator and Mediator-bound preinitiation complex.
Science, 372, 2021
7O4J
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BU of 7o4j by Molmil
Yeast RNA polymerase II transcription pre-initiation complex (consensus)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P.
Deposit date:2021-04-06
Release date:2021-06-16
Last modified:2021-08-04
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021
7O4I
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BU of 7o4i by Molmil
Yeast RNA polymerase II transcription pre-initiation complex with initial transcription bubble
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P.
Deposit date:2021-04-06
Release date:2021-06-16
Last modified:2021-08-04
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021
7O75
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BU of 7o75 by Molmil
Yeast RNA polymerase II transcription pre-initiation complex with open promoter DNA
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P.
Deposit date:2021-04-13
Release date:2021-06-16
Last modified:2021-08-04
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021
7O73
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BU of 7o73 by Molmil
Yeast RNA polymerase II transcription pre-initiation complex with closed distorted promoter DNA
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P.
Deposit date:2021-04-12
Release date:2021-06-16
Last modified:2021-08-04
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021
7O4K
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BU of 7o4k by Molmil
Yeast TFIIH in the contracted state within the pre-initiation complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P.
Deposit date:2021-04-06
Release date:2021-06-16
Last modified:2021-08-04
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021
7O4L
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BU of 7o4l by Molmil
Yeast TFIIH in the expanded state within the pre-initiation complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P.
Deposit date:2021-04-06
Release date:2021-06-16
Last modified:2021-08-04
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021
7O72
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BU of 7o72 by Molmil
Yeast RNA polymerase II transcription pre-initiation complex with closed promoter DNA
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P.
Deposit date:2021-04-12
Release date:2021-06-16
Last modified:2021-08-04
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021

 

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