5I4Q
| Contact-dependent inhibition system from Escherichia coli NC101 - ternary CdiA/CdiI/EF-Tu complex (domains 2 and 3) | Descriptor: | CHLORIDE ION, Contact-dependent inhibitor A, Contact-dependent inhibitor I, ... | Authors: | Michalska, K, Stols, L, Eschenfeldt, W, Hayes, C.S, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI) | Deposit date: | 2016-02-12 | Release date: | 2017-06-28 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structure of a novel antibacterial toxin that exploits elongation factor Tu to cleave specific transfer RNAs. Nucleic Acids Res., 45, 2017
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3E1Y
| Crystal structure of human eRF1/eRF3 complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, Eukaryotic peptide chain release factor subunit 1 | Authors: | Cheng, Z, Lim, M, Kong, C, Song, H. | Deposit date: | 2008-08-05 | Release date: | 2009-05-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Structural insights into eRF3 and stop codon recognition by eRF1 Genes Dev., 23, 2009
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3E20
| Crystal structure of S.pombe eRF1/eRF3 complex | Descriptor: | Eukaryotic peptide chain release factor GTP-binding subunit, Eukaryotic peptide chain release factor subunit 1 | Authors: | Cheng, Z, Lim, M, Kong, C, Song, H. | Deposit date: | 2008-08-05 | Release date: | 2009-05-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structural insights into eRF3 and stop codon recognition by eRF1 Genes Dev., 23, 2009
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1B23
| E. coli cysteinyl-tRNA and T. aquaticus elongation factor EF-TU:GTP ternary complex | Descriptor: | CYSTEINE, CYSTEINYL TRNA, ELONGATION FACTOR TU, ... | Authors: | Nissen, P, Kjeldgaard, M, Thirup, S, Nyborg, J. | Deposit date: | 1998-12-04 | Release date: | 1998-12-07 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The crystal structure of Cys-tRNACys-EF-Tu-GDPNP reveals general and specific features in the ternary complex and in tRNA. Structure Fold.Des., 7, 1999
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7CSL
| Crystal structure of the archaeal EF1A-EF1B complex | Descriptor: | Elongation factor 1-alpha, Elongation factor 1-beta | Authors: | Suzuki, T, Ito, K, Miyoshi, T, Murakami, R, Uchiumi, T. | Deposit date: | 2020-08-15 | Release date: | 2021-06-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural insights into the Switching Off of the Interaction between the Archaeal Ribosomal Stalk and aEF1A by Nucleotide Exchange Factor aEF1B. J.Mol.Biol., 433, 2021
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1AIP
| EF-TU EF-TS COMPLEX FROM THERMUS THERMOPHILUS | Descriptor: | ELONGATION FACTOR TS, ELONGATION FACTOR TU | Authors: | Wang, Y, Jiang, Y, Meyering-Voss, M, Sprinzl, M, Sigler, P.B. | Deposit date: | 1997-04-22 | Release date: | 1997-10-22 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of the EF-Tu.EF-Ts complex from Thermus thermophilus. Nat.Struct.Biol., 4, 1997
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8B6Z
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8V9L
| Cryo-EM structure of the Mycobacterium smegmatis 70S ribosome in complex with hibernation factor Msmeg1130 (Balon) and MsmegEF-Tu(GDP) (Composite structure 6) | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S2, ... | Authors: | Rybak, M.Y, Helena-Bueno, K, Hill, C.H, Melnikov, S.V, Gagnon, M.G. | Deposit date: | 2023-12-08 | Release date: | 2024-02-07 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | A new family of bacterial ribosome hibernation factors. Nature, 626, 2024
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3MMP
| Structure of the Qb replicase, an RNA-dependent RNA polymerase consisting of viral and host proteins | Descriptor: | (2S)-1-[3-{[(2R)-2-hydroxypropyl]oxy}-2,2-bis({[(2R)-2-hydroxypropyl]oxy}methyl)propoxy]propan-2-ol, Elongation factor Tu 2, Elongation factor Ts, ... | Authors: | Kidmose, R.T, Vasiliev, N.N, Chetverin, A.B, Knudsen, C.R, Andersen, G.R. | Deposit date: | 2010-04-20 | Release date: | 2010-06-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of the Qbeta replicase, an RNA-dependent RNA polymerase consisting of viral and host proteins. Proc.Natl.Acad.Sci.USA, 107, 2010
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6RA9
| Novel structural features and post-translational modifications in eukaryotic elongation factor 1A2 from Oryctolagus cuniculus | Descriptor: | Elongation factor 1-alpha 2, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Carriles, A.A, Hermoso, J, Gago, F. | Deposit date: | 2019-04-05 | Release date: | 2020-06-03 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural Cues for Understanding eEF1A2 Moonlighting. Chembiochem, 22, 2021
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6MIJ
| Crystal structure of EF-Tu from Acinetobacter baumannii in complex with Mg2+ and GDP | Descriptor: | Elongation factor Tu, FORMIC ACID, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Stogios, P.J, Evdokimova, E, Tan, K, Di Leo, R, Savchenko, A, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2018-09-19 | Release date: | 2018-10-03 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.955 Å) | Cite: | To be published To Be Published
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6EZE
| The open conformation of E.coli Elongation Factor Tu in complex with GDPNP. | Descriptor: | DI(HYDROXYETHYL)ETHER, Elongation factor Tu 2, GLYCEROL, ... | Authors: | Johansen, J.S, Blaise, M, Thirup, S.S. | Deposit date: | 2017-11-15 | Release date: | 2018-08-22 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | E. coli elongation factor Tu bound to a GTP analogue displays an open conformation equivalent to the GDP-bound form. Nucleic Acids Res., 46, 2018
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6JI2
| Crystal structure of archaeal ribosomal protein aP1, aPelota, and GTP-bound aEF1A complex | Descriptor: | Archaeal ribosomal stalk protein aP1, Elongation factor 1-alpha, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Maruyama, K, Imai, H, Kawamura, M, Ishino, S, Ishino, Y, Ito, K, Uchiumi, T. | Deposit date: | 2019-02-20 | Release date: | 2019-11-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Switch of the interactions between the ribosomal stalk and EF1A in the GTP- and GDP-bound conformations. Sci Rep, 9, 2019
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3J5Y
| Structure of the mammalian ribosomal pre-termination complex associated with eRF1-eRF3-GDPNP | Descriptor: | 5'-R(*AP*UP*UP*GP*UP*AP*AP*AP*AP*A)-3', Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, Eukaryotic peptide chain release factor subunit 1, ... | Authors: | des Georges, A, Hashem, Y, Unbehaun, A, Grassucci, R.A, Taylor, D, Hellen, C.U.T, Pestova, T.V, Frank, J. | Deposit date: | 2013-11-21 | Release date: | 2013-12-25 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (9.7 Å) | Cite: | Structure of the mammalian ribosomal pre-termination complex associated with eRF1*eRF3*GDPNP. Nucleic Acids Res., 42, 2014
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5O8W
| CRYSTAL STRUCTURE ANALYSIS OF THE YEAST ELONGATION FACTOR COMPLEX EEF1A:EEF1BA | Descriptor: | Elongation factor 1-alpha, Elongation factor 1-beta, GLUTAMINE, ... | Authors: | Wirth, C, Andersen, G.R, Hunte, C. | Deposit date: | 2017-06-14 | Release date: | 2017-08-23 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Protein glutaminylation is a yeast-specific posttranslational modification of elongation factor 1A. J. Biol. Chem., 292, 2017
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5OPD
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4ZV4
| Structure of Tse6 in complex with EF-Tu | Descriptor: | Elongation factor Tu, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Whitney, J.C, Sawai, S, Robinson, H, Mougous, J.D. | Deposit date: | 2015-05-18 | Release date: | 2015-11-11 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.504 Å) | Cite: | An Interbacterial NAD(P)(+) Glycohydrolase Toxin Requires Elongation Factor Tu for Delivery to Target Cells. Cell, 163, 2015
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8QFS
| Cryo-EM structure of SidH from Legionella pneumophila | Descriptor: | Elongation factor Tu, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Sharma, R, Weis, F, Bhogaraju, S. | Deposit date: | 2023-09-04 | Release date: | 2023-10-11 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structural basis for the toxicity of Legionella pneumophila effector SidH. Nat Commun, 14, 2023
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8QHC
| Cryo-EM structure of SidH from Legionella pneumophila in complex with LubX | Descriptor: | E3 ubiquitin--protein ligase, Elongation factor Tu, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Sharma, R, Adams, M, Bhogaraju, S. | Deposit date: | 2023-09-07 | Release date: | 2023-10-11 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis for the toxicity of Legionella pneumophila effector SidH. Nat Commun, 14, 2023
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5AFI
| 2.9A Structure of E. coli ribosome-EF-TU complex by cs-corrected cryo-EM | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Fischer, N, Neumann, P, Konevega, A.L, Bock, L.V, Ficner, R, Rodnina, M.V, Stark, H. | Deposit date: | 2015-01-22 | Release date: | 2015-03-11 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structure of the E. coli ribosome-EF-Tu complex at <3 angstrom resolution by Cs-corrected cryo-EM. Nature, 520, 2015
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6ZMO
| SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complex | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | Authors: | Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | Deposit date: | 2020-07-03 | Release date: | 2020-08-19 | Last modified: | 2020-09-16 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020
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7A5G
| Structure of the elongating human mitoribosome bound to mtEF-Tu.GMPPCP and A/T mt-tRNA | Descriptor: | 12S rRNA, 16S rRNA, 28S ribosomal protein S10, ... | Authors: | Desai, N, Yang, H, Chandrasekaran, V, Kazi, R, Minczuk, M, Ramakrishnan, V. | Deposit date: | 2020-08-21 | Release date: | 2020-12-23 | Method: | ELECTRON MICROSCOPY (4.33 Å) | Cite: | Elongational stalling activates mitoribosome-associated quality control. Science, 370, 2020
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2FX3
| Crystal Structure Determination of E. coli Elongation Factor, Tu using a Twinned Data Set | Descriptor: | Elongation factor Tu, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | Authors: | Heffron, S.E, Moeller, R, Jurnak, F. | Deposit date: | 2006-02-03 | Release date: | 2006-03-28 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Solving the structure of Escherichia coli elongation factor Tu using a twinned data set. Acta Crystallogr.,Sect.D, 62, 2006
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7ABZ
| Structure of pre-accomodated trans-translation complex on E. coli stalled ribosome. | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Guyomar, C, D'Urso, G, Chat, S, Giudice, E, Gillet, R. | Deposit date: | 2020-09-09 | Release date: | 2021-08-18 | Last modified: | 2021-09-29 | Method: | ELECTRON MICROSCOPY (3.21 Å) | Cite: | Structures of tmRNA and SmpB as they transit through the ribosome. Nat Commun, 12, 2021
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7VMC
| Crystal structure of EF-Tu/CdiA/CdiI | Descriptor: | Contact-dependent inhibitor I, Elongation factor Tu, tRNA nuclease CdiA | Authors: | Wang, J, Yashiro, Y, Tomita, K. | Deposit date: | 2021-10-08 | Release date: | 2022-03-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.413 Å) | Cite: | Mechanistic insights into tRNA cleavage by a contact-dependent growth inhibitor protein and translation factors. Nucleic Acids Res., 50, 2022
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