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7ZC9
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BU of 7zc9 by Molmil
Human Pikachurin/EGFLAM C-terminal Laminin-G domain (LG3)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Pikachurin, SULFATE ION
Authors:Pantalone, S, Forneris, F.
Deposit date:2022-03-26
Release date:2023-07-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the photoreceptor synaptic assembly of the extracellular matrix protein pikachurin with the orphan receptor GPR179.
Sci.Signal., 16, 2023
6CW1
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BU of 6cw1 by Molmil
Crystal structure of Neurexin-1 alpha ectodomain fragment, L2-L3
Descriptor: Neurexin-1
Authors:Misra, A, Rudenko, G.
Deposit date:2018-03-29
Release date:2018-09-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Structural Plasticity of Neurexin 1 alpha : Implications for its Role as Synaptic Organizer.
J. Mol. Biol., 430, 2018
1C4R
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BU of 1c4r by Molmil
THE STRUCTURE OF THE LIGAND-BINDING DOMAIN OF NEUREXIN 1BETA: REGULATION OF LNS DOMAIN FUNCTION BY ALTERNATIVE SPLICING
Descriptor: NEUREXIN-I BETA
Authors:Rudenko, G, Nguyen, T, Chelliah, Y, Sudhof, T.C, Deisenhofer, J.
Deposit date:1999-09-28
Release date:2000-10-04
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The structure of the ligand-binding domain of neurexin Ibeta: regulation of LNS domain function by alternative splicing.
Cell(Cambridge,Mass.), 99, 1999
2H0B
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BU of 2h0b by Molmil
Crystal Structure of the second LNS/LG domain from Neurexin 1 alpha
Descriptor: CALCIUM ION, GLYCEROL, Neurexin-1-alpha
Authors:Sheckler, L.R, Henry, L, Sugita, S, Sudhof, T.C, Rudenko, G.
Deposit date:2006-05-14
Release date:2006-06-20
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of the Second LNS/LG Domain from Neurexin 1{alpha}: Ca2+ binding and the effects of alternative splicing
J.Biol.Chem., 281, 2006
1QU0
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BU of 1qu0 by Molmil
CRYSTAL STRUCTURE OF THE FIFTH LAMININ G-LIKE MODULE OF THE MOUSE LAMININ ALPHA2 CHAIN
Descriptor: CALCIUM ION, LAMININ ALPHA2 CHAIN, SULFATE ION
Authors:Hohenester, E, Tisi, D, Talts, J.F, Timpl, R.
Deposit date:1999-07-05
Release date:1999-12-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The crystal structure of a laminin G-like module reveals the molecular basis of alpha-dystroglycan binding to laminins, perlecan, and agrin.
Mol.Cell, 4, 1999
2R1D
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BU of 2r1d by Molmil
Crystal structure of rat neurexin 1beta in the Ca2+ containing form
Descriptor: CALCIUM ION, Neurexin-1-beta
Authors:Rudenko, G.
Deposit date:2007-08-22
Release date:2008-04-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Regulation of Neurexin 1beta Tertiary Structure and Ligand Binding through Alternative Splicing
Structure, 16, 2008
2R1B
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BU of 2r1b by Molmil
Crystal Structure of rat neurexin 1beta with a splice insert at SS#4
Descriptor: CALCIUM ION, Neurexin-1-beta
Authors:Rudenko, G.
Deposit date:2007-08-22
Release date:2008-03-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Regulation of Neurexin 1beta Tertiary Structure and Ligand Binding through Alternative Splicing
Structure, 16, 2008
2R16
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BU of 2r16 by Molmil
Crystal Structure of bovine neurexin 1 alpha LNS/LG domain 4 (with no splice insert)
Descriptor: CALCIUM ION, Neurexin-1-alpha
Authors:Rudenko, G.
Deposit date:2007-08-22
Release date:2008-03-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.04 Å)
Cite:Regulation of Neurexin 1beta Tertiary Structure and Ligand Binding through Alternative Splicing
Structure, 16, 2008
3SH4
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BU of 3sh4 by Molmil
Laminin G like domain 3 from human perlecan
Descriptor: LG3 peptide
Authors:Van Le, B, Kim, K.K.
Deposit date:2011-06-15
Release date:2011-12-14
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal Structure of the LG3 Domain of Endorepellin, an Angiogenesis Inhibitor.
J.Mol.Biol., 414, 2011
3SH5
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BU of 3sh5 by Molmil
Calcium-bound Laminin G like domain 3 from human perlecan
Descriptor: CALCIUM ION, LG3 peptide
Authors:Van Le, B, Kim, K.K.
Deposit date:2011-06-16
Release date:2011-12-14
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of the LG3 Domain of Endorepellin, an Angiogenesis Inhibitor.
J.Mol.Biol., 414, 2011
3ASI
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BU of 3asi by Molmil
Alpha-Neurexin-1 ectodomain fragment; LNS5-EGF3-LNS6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neurexin-1-alpha
Authors:Tanaka, H, Nogi, T, Yasui, N, Takagi, J.
Deposit date:2010-12-13
Release date:2011-04-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis for Variant-Specific Neuroligin-Binding by alpha-Neurexin
Plos One, 6, 2011
3MW4
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BU of 3mw4 by Molmil
Crystal structure of beta-neurexin 3 without the splice insert 4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-D-mannopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neurexin-2-beta, ...
Authors:Jin, X, Shapiro, L.
Deposit date:2010-05-05
Release date:2010-07-28
Last modified:2021-10-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Splice Form Dependence of beta-Neurexin/Neuroligin Binding Interactions.
Neuron, 67, 2010
3MW3
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BU of 3mw3 by Molmil
Crystal structure of beta-neurexin 2 with the splice insert 4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-D-mannopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neurexin-2-beta
Authors:Jin, X, Shapiro, L.
Deposit date:2010-05-05
Release date:2010-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Splice Form Dependence of beta-Neurexin/Neuroligin Binding Interactions.
Neuron, 67, 2010
3MW2
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BU of 3mw2 by Molmil
Crystal structure of beta-neurexin 1 with the splice insert 4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-D-mannopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Neurexin-1-alpha, PHOSPHATE ION
Authors:Jin, X, Shapiro, L.
Deposit date:2010-05-05
Release date:2010-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Splice Form Dependence of beta-Neurexin/Neuroligin Binding Interactions.
Neuron, 67, 2010
3BOD
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BU of 3bod by Molmil
Structure of mouse beta-neurexin 1
Descriptor: CALCIUM ION, Neurexin-1-alpha
Authors:Koehnke, J, Jin, X, Shapiro, L.
Deposit date:2007-12-17
Release date:2008-03-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structures of beta-Neurexin 1 and beta-Neurexin 2 Ectodomains and Dynamics of Splice Insertion Sequence 4.
Structure, 16, 2008
3BOP
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BU of 3bop by Molmil
Structure of mouse beta-neurexin 2D4
Descriptor: beta-Neurexin 2D4
Authors:Koehnke, J, Jin, X, Shapiro, L.
Deposit date:2007-12-17
Release date:2008-03-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal Structures of beta-Neurexin 1 and beta-Neurexin 2 Ectodomains and Dynamics of Splice Insertion Sequence 4.
Structure, 16, 2008
6PNP
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BU of 6pnp by Molmil
Crystal structure of the splice insert-free neurexin-1 LNS2 domain in complex with neurexophilin-1
Descriptor: Neurexin-1, Neurexophilin-1
Authors:Wilson, S.C, White, K.I, Zhou, Q, Brunger, A.T.
Deposit date:2019-07-02
Release date:2019-10-09
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structures of neurexophilin-neurexin complexes reveal a regulatory mechanism of alternative splicing.
Embo J., 38, 2019
6PNQ
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BU of 6pnq by Molmil
Crystal structure of the SS2A splice insert-containing neurexin-1 LNS2 domain in complex with neurexophilin-1
Descriptor: Neurexin-1, Neurexophilin-1
Authors:Wilson, S.C, White, K.I, Zhou, Q, Brunger, A.T.
Deposit date:2019-07-02
Release date:2019-10-09
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.947 Å)
Cite:Structures of neurexophilin-neurexin complexes reveal a regulatory mechanism of alternative splicing.
Embo J., 38, 2019
5Z8Y
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BU of 5z8y by Molmil
Crystal structure of human LRRTM2 in complex with Neurexin 1beta
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Yamagata, A, Fukai, S.
Deposit date:2018-02-01
Release date:2018-10-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural insights into modulation and selectivity of transsynaptic neurexin-LRRTM interaction.
Nat Commun, 9, 2018
1H30
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BU of 1h30 by Molmil
C-terminal LG domain pair of human Gas6
Descriptor: CALCIUM ION, GROWTH-ARREST-SPECIFIC PROTEIN, SULFATE ION
Authors:Sasaki, T, Knyazev, P.G, Cheburkin, Y, Gohring, W, Tisi, D, Ullrich, A, Timpl, R, Hohenester, E.
Deposit date:2002-08-21
Release date:2003-01-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of a Carboxy-Terminal Fragment of Growth-Arrest-Specific Protein Gas6: Receptor Tyrosine Kinase Activation by Laminin G-Like Domains
J.Biol.Chem., 277, 2002
7CEC
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BU of 7cec by Molmil
Structure of alpha6beta1 integrin in complex with laminin-511
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Arimori, T, Miyazaki, N, Takagi, J.
Deposit date:2020-06-22
Release date:2021-06-23
Last modified:2021-07-14
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural mechanism of laminin recognition by integrin.
Nat Commun, 12, 2021
4RA0
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BU of 4ra0 by Molmil
An engineered Axl 'decoy receptor' effectively silences the Gas6-Axl signaling axis
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
Authors:Kariolis, M.S, Kapur, S, Mathews, I.I, Cochran, J.R.
Deposit date:2014-09-09
Release date:2014-09-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.07 Å)
Cite:An engineered Axl 'decoy receptor' effectively silences the Gas6-Axl signaling axis.
Nat.Chem.Biol., 10, 2014
1DYK
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BU of 1dyk by Molmil
Laminin alpha 2 chain LG4-5 domain pair
Descriptor: CALCIUM ION, LAMININ ALPHA 2 CHAIN
Authors:Tisi, D, Talts, J.F, Timple, R, Hohenester, E.
Deposit date:2000-02-01
Release date:2001-02-04
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the C-Terminal Laminin G-Like Domain Pair of the Laminin Alpha 2 Chain Harbouring Binding Sites for Alpha-Dystroglycan and Heparin
Embo J., 19, 2000
7ML7
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BU of 7ml7 by Molmil
Structural basis for CSPG4 as a receptor for TcdB and a therapeutic target in Clostridioides difficile infection
Descriptor: Chondroitin sulfate proteoglycan 4, Toxin B, ZINC ION
Authors:Chen, P, Jin, R.
Deposit date:2021-04-27
Release date:2021-06-09
Last modified:2021-06-30
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Structural basis for CSPG4 as a receptor for TcdB and a therapeutic target in Clostridioides difficile infection.
Nat Commun, 12, 2021
8D1B
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BU of 8d1b by Molmil
CryoEM structure of human orphan GPCR GPR179 in complex with extracellular matrix protein pikachurin
Descriptor: Pikachurin, Probable G-protein coupled receptor 179
Authors:Patil, D.N, Martemyanov, K.A.
Deposit date:2022-05-27
Release date:2023-07-26
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:Structure of the photoreceptor synaptic assembly of the extracellular matrix protein pikachurin with the orphan receptor GPR179.
Sci.Signal., 16, 2023

 

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