1F81
 
 | | SOLUTION STRUCTURE OF THE TAZ2 DOMAIN OF THE TRANSCRIPTIONAL ADAPTOR PROTEIN CBP | | Descriptor: | CREB-BINDING PROTEIN, ZINC ION | | Authors: | De Guzman, R.N, Liu, H.L, Martinez-Yamout, M, Dyson, H.J, Wright, P.E. | | Deposit date: | 2000-06-28 | | Release date: | 2000-10-18 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the TAZ2 (CH3) domain of the transcriptional adaptor protein CBP.
J.Mol.Biol., 303, 2000
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1L3E
 | | NMR Structures of the HIF-1alpha CTAD/p300 CH1 Complex | | Descriptor: | ZINC ION, hypoxia inducible factor-1 alpha subunit, p300 protein | | Authors: | Freedman, S.J, Sun, Z.J, Poy, F, Kung, A.L, Livingston, D.M, Wagner, G, Eck, M.J. | | Deposit date: | 2002-02-26 | | Release date: | 2002-04-24 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1 alpha.
Proc.Natl.Acad.Sci.USA, 99, 2002
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1L8C
 | | STRUCTURAL BASIS FOR HIF-1ALPHA/CBP RECOGNITION IN THE CELLULAR HYPOXIC RESPONSE | | Descriptor: | CREB-binding protein, Hypoxia-inducible factor 1 alpha, ZINC ION | | Authors: | Dames, S.A, Martinez-Yamout, M, De Guzman, R.N, Dyson, H.J, Wright, P.E. | | Deposit date: | 2002-03-19 | | Release date: | 2002-04-10 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Structural basis for Hif-1 alpha /CBP recognition in the cellular hypoxic response.
Proc.Natl.Acad.Sci.USA, 99, 2002
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1LIQ
 | | Non-native Solution Structure of a fragment of the CH1 domain of CBP | | Descriptor: | CREB Binding Protein, ZINC ION | | Authors: | Sharpe, B.K, Matthews, J.M, Kwan, A.H.Y, Newton, A, Gell, D.A, Crossley, M, Mackay, J.P. | | Deposit date: | 2002-04-18 | | Release date: | 2002-05-29 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | A New Zinc Binding Fold Underlines the Versatility of Zinc Binding Modules in Protein Evolution
Structure, 10, 2002
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1P4Q
 | | Solution structure of the CITED2 transactivation domain in complex with the p300 CH1 domain | | Descriptor: | Cbp/p300-interacting transactivator 2, E1A-associated protein p300, ZINC ION | | Authors: | Freedman, S.J, Sun, Z.-Y.J, Kung, A.L, France, D.S, Wagner, G, Eck, M.J. | | Deposit date: | 2003-04-23 | | Release date: | 2003-07-01 | | Last modified: | 2017-02-01 | | Method: | SOLUTION NMR | | Cite: | Structural basis for negative regulation of hypoxia-inducible factor-1alpha by CITED2.
Nat.Struct.Biol., 10, 2003
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1R8U
 | | NMR structure of CBP TAZ1/CITED2 complex | | Descriptor: | CREB-binding protein, Cbp/p300-interacting transactivator 2, ZINC ION | | Authors: | De Guzman, R.N, Martinez-Yamout, M, Dyson, H.J, Wright, P.E. | | Deposit date: | 2003-10-28 | | Release date: | 2004-03-23 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | Interaction of the TAZ1 domain of the CREB-binding protein with the activation domain of CITED2: regulation by competition between intrinsically unstructured ligands for non-identical binding sites.
J.Biol.Chem., 279, 2004
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1U2N
 | | Structure CBP TAZ1 Domain | | Descriptor: | CREB binding protein, ZINC ION | | Authors: | De Guzman, R.N, Wojciak, J.M, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E. | | Deposit date: | 2004-07-19 | | Release date: | 2005-04-26 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | CBP/p300 TAZ1 domain forms a structured scaffold for ligand binding
Biochemistry, 44, 2005
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1WO3
 | | Solution structure of Minimal Mutant 1 (MM1): Multiple alanine mutant of non-native CHANCE domain | | Descriptor: | CREB Binding Protein, ZINC ION | | Authors: | Sharpe, B.K, Liew, C.K, Wilce, J.A, Crossley, M, Matthews, J.M, Mackay, J.P. | | Deposit date: | 2004-08-12 | | Release date: | 2005-03-08 | | Last modified: | 2021-11-10 | | Method: | SOLUTION NMR | | Cite: | Assessment of the robustness of a serendipitous zinc binding fold: mutagenesis and protein grafting
Structure, 13, 2005
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1WO6
 | | Solution structure of Designed Functional Finger 5 (DFF5): Designed mutant based on non-native CHANCE domain | | Descriptor: | CREB Binding Protein, ZINC ION | | Authors: | Sharpe, B.K, Liew, C.K, Wilce, J.A, Crossley, M, Matthews, J.M, Mackay, J.P. | | Deposit date: | 2004-08-12 | | Release date: | 2005-03-08 | | Last modified: | 2021-11-10 | | Method: | SOLUTION NMR | | Cite: | Assessment of the robustness of a serendipitous zinc binding fold: mutagenesis and protein grafting
Structure, 13, 2005
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1WO4
 | | Solution structure of Minimal Mutant 2 (MM2): Multiple alanine mutant of non-native CHANCE domain | | Descriptor: | CREB Binding Protein, ZINC ION | | Authors: | Sharpe, B.K, Liew, C.K, Wilce, J.A, Crossley, M, Matthews, J.M, Mackay, J.P. | | Deposit date: | 2004-08-12 | | Release date: | 2005-03-08 | | Last modified: | 2021-11-10 | | Method: | SOLUTION NMR | | Cite: | Assessment of the robustness of a serendipitous zinc binding fold: mutagenesis and protein grafting
Structure, 13, 2005
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1WO5
 | | Solution structure of Designed Functional Finger 2 (DFF2): Designed mutant based on non-native CHANCE domain | | Descriptor: | CREB Binding Protein, ZINC ION | | Authors: | Sharpe, B.K, Liew, C.K, Wilce, J.A, Crossley, M, Matthews, J.M, Mackay, J.P. | | Deposit date: | 2004-08-12 | | Release date: | 2005-03-08 | | Last modified: | 2021-11-10 | | Method: | SOLUTION NMR | | Cite: | Assessment of the robustness of a serendipitous zinc binding fold: mutagenesis and protein grafting
Structure, 13, 2005
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1WO7
 | | Solution structure of Designed Functional Finger 7 (DFF7): Designed mutant based on non-native CHANCE domain | | Descriptor: | CREB Binding Protein, ZINC ION | | Authors: | Sharpe, B.K, Liew, C.K, Wilce, J.A, Crossley, M, Matthews, J.M, Mackay, J.P. | | Deposit date: | 2004-08-12 | | Release date: | 2005-03-08 | | Last modified: | 2021-11-10 | | Method: | SOLUTION NMR | | Cite: | Assessment of the robustness of a serendipitous zinc binding fold: mutagenesis and protein grafting
Structure, 13, 2005
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2K8F
 | | Structural Basis for the Regulation of p53 Function by p300 | | Descriptor: | Cellular tumor antigen p53, Histone acetyltransferase p300 | | Authors: | Bai, Y, Feng, H, Jenkins, L.M, Durell, S.R, Wiodawer, A, Appella, E. | | Deposit date: | 2008-09-08 | | Release date: | 2009-03-03 | | Last modified: | 2021-10-20 | | Method: | SOLUTION NMR | | Cite: | Structural Basis for p300 Taz2-p53 TAD1 Binding and Modulation by Phosphorylation.
Structure, 17, 2009
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2KA4
 | | NMR structure of the CBP-TAZ1/STAT2-TAD complex | | Descriptor: | Crebbp protein, Signal transducer and activator of transcription 2, ZINC ION | | Authors: | Wojciak, J.M, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E. | | Deposit date: | 2008-10-30 | | Release date: | 2009-04-21 | | Last modified: | 2021-10-20 | | Method: | SOLUTION NMR | | Cite: | Structural basis for recruitment of CBP/p300 coactivators by STAT1 and STAT2 transactivation domains
Embo J., 28, 2009
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2KA6
 | | NMR structure of the CBP-TAZ2/STAT1-TAD complex | | Descriptor: | CREB-binding protein, Signal transducer and activator of transcription 1-alpha/beta, ZINC ION | | Authors: | Wojciak, J.M, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E. | | Deposit date: | 2008-10-30 | | Release date: | 2009-04-07 | | Last modified: | 2021-10-20 | | Method: | SOLUTION NMR | | Cite: | Structural basis for recruitment of CBP/p300 coactivators by STAT1 and STAT2 transactivation domains.
Embo J., 28, 2009
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2KJE
 | | NMR structure of CBP TAZ2 and adenoviral E1A complex | | Descriptor: | CREB-binding protein, Early E1A 32 kDa protein, ZINC ION | | Authors: | Ferreon, J.C, Martinez-Yamout, M, Dyson, H, Wright, P.E. | | Deposit date: | 2009-05-27 | | Release date: | 2009-09-15 | | Last modified: | 2022-03-16 | | Method: | SOLUTION NMR | | Cite: | Structural basis for subversion of cellular control mechanisms by the adenoviral E1A oncoprotein.
Proc.Natl.Acad.Sci.USA, 106, 2009
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3IO2
 | | Crystal structure of the Taz2 domain of p300 | | Descriptor: | Histone acetyltransferase p300, SULFATE ION, ZINC ION | | Authors: | Miller, M, Dauter, Z, Wlodawer, A. | | Deposit date: | 2009-08-13 | | Release date: | 2009-11-24 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of the Taz2 domain of p300: insights into ligand binding.
Acta Crystallogr.,Sect.D, 65, 2009
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3P57
 | | Crystal structure of the p300 TAZ2 domain bound to MEF2 on DNA | | Descriptor: | DNA (5'-D(*A*AP*AP*CP*TP*AP*TP*TP*TP*AP*TP*AP*AP*GP*A)-3'), DNA (5'-D(*TP*TP*CP*TP*TP*AP*TP*AP*AP*AP*TP*AP*GP*TP*T)-3'), Histone acetyltransferase p300, ... | | Authors: | He, J, Ye, J, Riquelme, C, Liu, J.O. | | Deposit date: | 2010-10-08 | | Release date: | 2011-08-10 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.1921 Å) | | Cite: | Structure of p300 bound to MEF2 on DNA reveals a mechanism of enhanceosome assembly.
Nucleic Acids Res., 39, 2011
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3T92
 | | Crystal structure of the Taz2:C/EBPepsilon-TAD chimera protein | | Descriptor: | 3,3',3''-phosphanetriyltripropanoic acid, ACETONE, HISTONE ACETYLTRANSFERASE P300 TAZ2-CCAAT/ENHANCER-BINDING PROTEIN EPSILON, ... | | Authors: | Bhaumik, P, Maria, M. | | Deposit date: | 2011-08-02 | | Release date: | 2012-08-08 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural insights into interactions of C/EBP transcriptional activators with the Taz2 domain of p300.
Acta Crystallogr. D Biol. Crystallogr., 70, 2014
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2LWW
 | | NMR structure of RelA-TAD/CBP-TAZ1 complex | | Descriptor: | CREB-binding protein, Nuclear transcription factor RelA, ZINC ION | | Authors: | Mukherjee, S.P, Ghosh, G, Wright, P.E. | | Deposit date: | 2012-08-07 | | Release date: | 2013-09-11 | | Last modified: | 2013-09-18 | | Method: | SOLUTION NMR | | Cite: | Analysis of the RelA:CBP/p300 Interaction Reveals Its Involvement in NF-kappa B-Driven Transcription.
Plos Biol., 11, 2013
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2MH0
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2MZD
 | | Characterization of the p300 Taz2-p53 TAD2 Complex and Comparison with the p300 Taz2-p53 TAD1 Complex | | Descriptor: | Cellular tumor antigen p53, Histone acetyltransferase p300 | | Authors: | Miller Jenkins, L.M, Feng, H, Durell, S.R, Tagad, H.D, Mazur, S.J, Tropea, J.E, Bai, Y, Appella, E. | | Deposit date: | 2015-02-11 | | Release date: | 2015-03-25 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Characterization of the p300 Taz2-p53 TAD2 Complex and Comparison with the p300 Taz2-p53 TAD1 Complex.
Biochemistry, 54, 2015
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5HP0
 | | Solution Structure of TAZ2-p53AD2 | | Descriptor: | CREB-binding protein,Cellular tumor antigen p53 fusion protein, ZINC ION | | Authors: | Krois, A.S, Ferreon, J.C, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E. | | Deposit date: | 2016-01-19 | | Release date: | 2016-03-16 | | Last modified: | 2019-12-04 | | Method: | SOLUTION NMR | | Cite: | Recognition of the disordered p53 transactivation domain by the transcriptional adapter zinc finger domains of CREB-binding protein.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5HOU
 | | Solution Structure of p53TAD-TAZ1 | | Descriptor: | Cellular tumor antigen p53,CREB-binding protein fusion protein, ZINC ION | | Authors: | Krois, A.S, Ferreon, J.C, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E. | | Deposit date: | 2016-01-19 | | Release date: | 2016-03-16 | | Last modified: | 2019-12-04 | | Method: | SOLUTION NMR | | Cite: | Recognition of the disordered p53 transactivation domain by the transcriptional adapter zinc finger domains of CREB-binding protein.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5HPD
 | | Solution Structure of TAZ2-p53TAD | | Descriptor: | CREB-binding protein,Cellular tumor antigen p53 fusion protein, ZINC ION | | Authors: | Krois, A.S, Ferreon, J.C, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E. | | Deposit date: | 2016-01-20 | | Release date: | 2016-03-16 | | Last modified: | 2019-12-04 | | Method: | SOLUTION NMR | | Cite: | Recognition of the disordered p53 transactivation domain by the transcriptional adapter zinc finger domains of CREB-binding protein.
Proc.Natl.Acad.Sci.USA, 113, 2016
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