7VWO
 
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6SD6
 | | Structure of VapBC from Shigella sonnei | | Descriptor: | Antitoxin, tRNA(fMet)-specific endonuclease VapC | | Authors: | Lea, S.M, Hollingshead, S. | | Deposit date: | 2019-07-26 | | Release date: | 2020-08-26 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.61 Å) | | Cite: | Polymorphisms in the VapBC toxin:antitoxin system mediate high frequency plasmid loss in Shigella sonnei
To Be Published
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5K8J
 | | Structure of Caulobacter crescentus VapBC1 (apo form) | | Descriptor: | GLYCEROL, Ribonuclease VapC, VapB family protein | | Authors: | Bendtsen, K.L, Xu, K, Luckmann, M, Brodersen, D.E. | | Deposit date: | 2016-05-30 | | Release date: | 2016-12-28 | | Last modified: | 2018-01-17 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Toxin inhibition in C. crescentus VapBC1 is mediated by a flexible pseudo-palindromic protein motif and modulated by DNA binding.
Nucleic Acids Res., 45, 2017
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5SV2
 | | Toxin VapC21 from Mycobacterium tuberculosis | | Descriptor: | Ribonuclease VapC21 | | Authors: | Valadares, N.F. | | Deposit date: | 2016-08-04 | | Release date: | 2016-09-14 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.31 Å) | | Cite: | Crystal structure of VapC21 from Mycobacterium tuberculosis at 1.31 angstrom resolution.
Biochem.Biophys.Res.Commun., 478, 2016
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5L6M
 | | Structure of Caulobacter crescentus VapBC1 (VapB1deltaC:VapC1 form) | | Descriptor: | GLYCEROL, MALONATE ION, Ribonuclease VapC, ... | | Authors: | Bendtsen, K.L, Xu, K, Luckmann, M, Brodersen, D.E. | | Deposit date: | 2016-05-30 | | Release date: | 2016-12-28 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Toxin inhibition in C. crescentus VapBC1 is mediated by a flexible pseudo-palindromic protein motif and modulated by DNA binding.
Nucleic Acids Res., 45, 2017
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5L6L
 | | Structure of Caulobacter crescentus VapBC1 bound to operator DNA | | Descriptor: | DNA (27-MER), Ribonuclease VapC, VapB family protein | | Authors: | Bendtsen, K.L, Xu, K, Luckmann, M, Brodersen, D.E. | | Deposit date: | 2016-05-30 | | Release date: | 2016-12-28 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Toxin inhibition in C. crescentus VapBC1 is mediated by a flexible pseudo-palindromic protein motif and modulated by DNA binding.
Nucleic Acids Res., 45, 2017
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2H1C
 | | Crystal Structure of FitAcB from Neisseria gonorrhoeae | | Descriptor: | ACETATE ION, MAGNESIUM ION, SULFATE ION, ... | | Authors: | Mattison, K, Wilbur, J.S, So, M, Brennan, R.G. | | Deposit date: | 2006-05-16 | | Release date: | 2006-09-26 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure of FitAB from Neisseria gonorrhoeae bound to DNA reveals a tetramer of toxin-antitoxin heterodimers containing pin domains and ribbon-helix-helix motifs.
J.Biol.Chem., 281, 2006
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2H1O
 | | Structure of FitAB bound to IR36 DNA fragment | | Descriptor: | IR36-strand 1, IR36-strand 2, Trafficking protein A, ... | | Authors: | Mattison, K, Wilbur, J.S, So, M, Brennan, R.G. | | Deposit date: | 2006-05-16 | | Release date: | 2006-09-26 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure of FitAB from Neisseria gonorrhoeae bound to DNA reveals a tetramer of toxin-antitoxin heterodimers containing pin domains and ribbon-helix-helix motifs.
J.Biol.Chem., 281, 2006
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6IFM
 | | Crystal structure of DNA bound VapBC from Salmonella typhimurium | | Descriptor: | Antitoxin VapB, DNA backward (27-MER), DNA forward (27-MER), ... | | Authors: | Park, D.W, Lee, B.J. | | Deposit date: | 2018-09-20 | | Release date: | 2020-01-29 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.804 Å) | | Cite: | Crystal structure of proteolyzed VapBC and DNA-bound VapBC from Salmonella enterica Typhimurium LT2 and VapC as a putative Ca2+-dependent ribonuclease.
Faseb J., 34, 2020
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6IFC
 | | Crystal structure of VapBC from Salmonella typhimurium | | Descriptor: | Antitoxin VapB, CALCIUM ION, tRNA(fMet)-specific endonuclease VapC | | Authors: | Park, D.W, Lee, B.J. | | Deposit date: | 2018-09-19 | | Release date: | 2020-01-29 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Crystal structure of proteolyzed VapBC and DNA-bound VapBC from Salmonella enterica Typhimurium LT2 and VapC as a putative Ca2+-dependent ribonuclease.
Faseb J., 34, 2020
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3IX7
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3TND
 | | Crystal structure of Shigella flexneri VapBC toxin-antitoxin complex | | Descriptor: | Antitoxin VapB, SODIUM ION, SULFATE ION, ... | | Authors: | Dienemann, C, Boggild, A, Winther, K.S, Gerdes, K, Brodersen, D.E. | | Deposit date: | 2011-09-01 | | Release date: | 2011-11-02 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal Structure of the VapBC Toxin-Antitoxin Complex from Shigella flexneri Reveals a Hetero-Octameric DNA-Binding Assembly.
J.Mol.Biol., 414, 2011
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3I8O
 | | A domain of a functionally unknown protein from Methanocaldococcus jannaschii DSM 2661. | | Descriptor: | ACETATE ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Tan, K, Chhor, G, Cobb, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2009-07-09 | | Release date: | 2009-07-21 | | Last modified: | 2019-07-24 | | Method: | X-RAY DIFFRACTION (2.638 Å) | | Cite: | A domain of a functionally unknown protein from Methanocaldococcus jannaschii DSM 2661.
To be Published
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2BSQ
 | | FitAB bound to DNA | | Descriptor: | IR36, FORWARD STRAND, REVERSE STRAND, ... | | Authors: | Mattison, K, Wilbur, J.S, So, M, Brennan, R.G. | | Deposit date: | 2005-05-23 | | Release date: | 2006-08-24 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure of Fitab from Neisseria Gonorrhoeae Bound to DNA Reveals a Tetramer of Toxin-Antitoxin Heterodimers Containing Pin Domains and Ribbon-Helix-Helix Motifs.
J.Biol.Chem., 281, 2006
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3ZVK
 | | Crystal structure of VapBC2 from Rickettsia felis bound to a DNA fragment from their promoter | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ANTITOXIN OF TOXIN-ANTITOXIN SYSTEM VAPB, DNA, ... | | Authors: | Mate, M.J, Ortiz-Lombardia, M, Cambillau, C. | | Deposit date: | 2011-07-25 | | Release date: | 2011-12-14 | | Last modified: | 2012-04-25 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal Structure of the DNA-Bound Vapbc2 Antitoxin/Toxin Pair from Rickettsia Felis.
Nucleic Acids Res., 40, 2012
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2FE1
 | | Crystal Structure of PAE0151 from Pyrobaculum aerophilum | | Descriptor: | CALCIUM ION, CHLORIDE ION, MANGANESE (II) ION, ... | | Authors: | Bunker, R.D, Baker, E.N, Arcus, V.L. | | Deposit date: | 2005-12-15 | | Release date: | 2005-12-27 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of PAE0151 from Pyrobaculum aerophilum, a PIN-domain (VapC) protein from a toxin-antitoxin operon.
Proteins, 72, 2008
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5WZF
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5WZ4
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5ECD
 | | Structure of the Shigella flexneri VapC mutant D98N crystal form 1 | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, tRNA(fMet)-specific endonuclease VapC | | Authors: | Xu, K. | | Deposit date: | 2015-10-20 | | Release date: | 2016-02-17 | | Last modified: | 2018-01-17 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structural analysis of the active site architecture of the VapC toxin from Shigella flexneri.
Proteins, 84, 2016
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1V8P
 | | Crystal structure of PAE2754 from Pyrobaculum aerophilum | | Descriptor: | CHLORIDE ION, hypothetical protein PAE2754 | | Authors: | Arcus, V.L, Backbro, K, Roos, A, Daniel, E.L, Baker, E.N. | | Deposit date: | 2004-01-12 | | Release date: | 2004-02-10 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.52 Å) | | Cite: | Distant structural homology leads to the functional characterization of an archaeal PIN domain as an exonuclease
J.Biol.Chem., 279, 2004
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5ED0
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5ECY
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5ECW
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1V8O
 | | Crystal Structure of PAE2754 from Pyrobaculum aerophilum | | Descriptor: | CHLORIDE ION, hypothetical protein PAE2754 | | Authors: | Arcus, V.L, Backbro, K, Roos, A, Daniel, E.L, Baker, E.N. | | Deposit date: | 2004-01-12 | | Release date: | 2004-02-10 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Distant structural homology leads to the functional characterization of an archaeal PIN domain as an exonuclease
J.Biol.Chem., 279, 2004
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1W8I
 | | The Structure of gene product af1683 from Archaeoglobus fulgidus. | | Descriptor: | PUTATIVE VAPC RIBONUCLEASE AF_1683 | | Authors: | Midwest Center for Structural Genomics (MCSG), Cuff, M.E, Zhang, R, Ginell, S.L, Xu, X, Savchenko, A, Edwards, A, Joachimiak, A. | | Deposit date: | 2004-09-22 | | Release date: | 2004-11-16 | | Last modified: | 2017-06-28 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The Structure of Gene Product Af1683 from Archaeoglobus Fulgidus
To be Published
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