PDB: 248 resultsInfo pagesStatus searchChemie searchBIRD

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7W9S	Crystal structure of the enterovirus 71 polymerase elongation complex (C1S3 form) Descriptor: CYTIDINE-5'-TRIPHOSPHATE, Genome polyprotein, MAGNESIUM ION, ... Authors: Wang, M, Gong, P. Deposit date: 2021-12-10 Release date: 2022-11-16 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.53 Å) Cite: Crystal structure of a pre-chemistry viral RNA-dependent RNA polymerase suggests participation of two basic residues in catalysis. Nucleic Acids Res., 50, 2022
2WK4	Dimeric structure of D347G D348G mutant of the sapporovirus RNA dependent RNA polymerase Descriptor: GLYCEROL, PROTEASE-POLYMERASE P70 Authors: Fullerton, S.W.B, Robel, I, Schuldt, L, Gebhardt, J, Tucker, P.A, Rohayem, J. Deposit date: 2009-06-05 Release date: 2010-09-01 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.98 Å) Cite: Dimeric Structure of D347G D348G Mutant of the Sapporovirus Sapporovirus RNA Dependent RNA Polymerase To be Published
1HHS	RNA dependent RNA polymerase from dsRNA bacteriophage phi6 Descriptor: MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE Authors: Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. Deposit date: 2000-12-28 Release date: 2001-03-27 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2 Å) Cite: A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
8IIB	Crystal structure of Israeli acute paralysis virus RNA-dependent RNA polymerase delta85 mutant (residues 86-546) Descriptor: CADMIUM ION, CHLORIDE ION, MAGNESIUM ION, ... Authors: Fang, X, Lu, G, Hou, C, Gong, P. Deposit date: 2023-02-24 Release date: 2023-06-07 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.69 Å) Cite: Unusual substructure conformations observed in crystal structures of a dicistrovirus RNA-dependent RNA polymerase suggest contribution of the N-terminal extension in proper folding. Virol Sin, 38, 2023
8IIC	Crystal structure of Israeli acute paralysis virus RNA-dependent RNA polymerase delta40 mutant (residues 41-546) Descriptor: Polymerase polyprotein Authors: Fang, X, Lu, G, Hou, C, Gong, P. Deposit date: 2023-02-24 Release date: 2023-06-07 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (3.25 Å) Cite: Unusual substructure conformations observed in crystal structures of a dicistrovirus RNA-dependent RNA polymerase suggest contribution of the N-terminal extension in proper folding. Virol Sin, 38, 2023
4WFZ	Coxsackievirus B3 3Dpol RNA Dependent RNA Polymerase - NaCl Crystal Form Descriptor: RNA-directed RNA polymerase, SODIUM ION Authors: Peersen, O.B, McDonald, S.M. Deposit date: 2014-09-17 Release date: 2014-10-22 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.803 Å) Cite: Structure-Function Relationships Underlying the Replication Fidelity of Viral RNA-Dependent RNA Polymerases. J.Virol., 89, 2015
4WFY	Coxsackievirus B3 Polymerase - F232L Mutant - AmSO4 Crystal Form Descriptor: GLYCEROL, RNA-directed RNA polymerase, SULFATE ION Authors: Peersen, O.B, McDonald, S.M. Deposit date: 2014-09-17 Release date: 2014-10-22 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.06 Å) Cite: Structure-Function Relationships Underlying the Replication Fidelity of Viral RNA-Dependent RNA Polymerases. J.Virol., 89, 2015
8C2P	FMDV 3D polymerase in complex with 3B3 Descriptor: Protein 3B-3, RNA-directed RNA polymerase 3D-POL Authors: Ferrer-Orta, C, Veraguer, N. Deposit date: 2022-12-22 Release date: 2023-04-26 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Dual role of the foot-and-mouth disease virus 3B1 protein in the replication complex: As protein primer and as an essential component to recruit 3Dpol to membranes. Plos Pathog., 19, 2023
8C1N	FMDV 3D polymerase in complex with 3B1 protein solved in P212121 space group Descriptor: ACETATE ION, GLYCEROL, Protein 3B-1, ... Authors: Ferrer-Orta, C, Veraguer, N. Deposit date: 2022-12-20 Release date: 2023-04-26 Last modified: 2023-05-10 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Dual role of the foot-and-mouth disease virus 3B1 protein in the replication complex: As protein primer and as an essential component to recruit 3Dpol to membranes. Plos Pathog., 19, 2023
4R0E	Crystal Structure of the Poliovirus RNA-Dependent RNA Polymerase Low-Fidelity Mutant 3Dpol H273R Descriptor: RNA-directed RNA polymerase Authors: Marcotte, L.L, Gohara, D.W, Filman, D.J, Hogle, J.M. Deposit date: 2014-07-30 Release date: 2014-11-12 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural Dynamics as a Contributor to Error-prone Replication by an RNA-dependent RNA Polymerase. J.Biol.Chem., 289, 2014
4QPX	NV polymerase post-incorporation-like complex Descriptor: GLYCEROL, MANGANESE (II) ION, Polyprotein, ... Authors: Zamyatkin, D.F, Parra, F, Grochulski, P, Ng, K.K.S. Deposit date: 2014-06-25 Release date: 2015-04-22 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.86 Å) Cite: Structure of a backtracked state reveals conformational changes similar to the state following nucleotide incorporation in human norovirus polymerase. Acta Crystallogr.,Sect.D, 70, 2014
5TSN	Crystal structures of Norwalk virus polymerase bound to an RNA primer-template duplex Descriptor: MANGANESE (II) ION, Norwalk virus polymerase, RNA (5'-R(*UP*GP*CP*CP*CP*GP*GP*G)-3') Authors: Shaik, M.M, Ng, K.K. Deposit date: 2016-10-30 Release date: 2017-04-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Norovirus RNA-dependent RNA polymerase: A computational study of metal-binding preferences. Proteins, 85, 2017
5N8X	Trigonal structure of mutant V173I of 3D polymerase from Foot-and-Mouth Disease Virus Descriptor: 3D polymerase, GLYCEROL, MANGANESE (II) ION Authors: Ferrer-Orta, C, Verdaguer, N. Deposit date: 2017-02-24 Release date: 2017-05-10 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Molecular and Functional Bases of Selection against a Mutation Bias in an RNA Virus. Genome Biol Evol, 9, 2017
5N95	Tetragonal structure of mutant V173I of 3D polymerase from Foot-and-Mouth Disease Virus Descriptor: 3D polymerase, TRIPHOSPHATE Authors: Ferrer-Orta, C, Verdaguer, N. Deposit date: 2017-02-24 Release date: 2017-05-10 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Molecular and Functional Bases of Selection against a Mutation Bias in an RNA Virus. Genome Biol Evol, 9, 2017
6GVV	Mutant M16A of RNA dependent RNA polymerase 3D from Foot-and-Mouth disease Virus Descriptor: GLYCEROL, RNA polymerase 3D Authors: Verdaguer, N, Ferrer Orta, C. Deposit date: 2018-06-21 Release date: 2018-08-01 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Contribution of a Multifunctional Polymerase Region of Foot-and-Mouth Disease Virus to Lethal Mutagenesis. J.Virol., 92, 2018
6GVY	Mutant M16A of RNA dependent RNA polymerase 3D from Foot-and-Mouth disease Virus complexed with an template -primer RNA Descriptor: GLYCEROL, Genome polyprotein, RNA (5'-R(P*CP*CP*GP*GP*G)-3'), ... Authors: Verdaguer, N, Ferrer-Orta, C. Deposit date: 2018-06-21 Release date: 2018-08-01 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Contribution of a Multifunctional Polymerase Region of Foot-and-Mouth Disease Virus to Lethal Mutagenesis. J. Virol., 92, 2018
5XE0	Crystal structure of EV-D68-3Dpol in complex with GTP Descriptor: GUANOSINE-5'-TRIPHOSPHATE, Genome polyprotein Authors: Xie, W, Wang, C, Wang, Z, Li, Q, Wang, C. Deposit date: 2017-03-30 Release date: 2017-06-28 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal Structure and Thermostability Characterization of Enterovirus D68 3Dpol J. Virol., 91, 2017
2UUT	The 2.4 angstrom resolution structure of the D346G mutant of the Sapporo Virus RdRp polymerase Descriptor: RNA-DIRECTED RNA POLYMERASE Authors: Fullerton, S.W.B, Robel, I, Schuldt, L, Gebhardt, J, Tucker, P, Rohayem, J. Deposit date: 2007-03-07 Release date: 2007-05-01 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.4 Å) Cite: The 2.4 Angstrom Resolution Structure of the D346G Mutant of the Sapporo Virus Rdrp Polymerase To be Published
2UUW	2.75 angstrom structure of the D347G D348G mutant structure of Sapporo Virus RdRp Polymerase Descriptor: RNA-DIRECTED RNA POLYMERASE Authors: Fullerton, S, Robel, I, Schuldt, L, Gebhardt, J, Tucker, P, Rohayem, J. Deposit date: 2007-03-07 Release date: 2007-05-01 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.76 Å) Cite: The 2.76 Angstrom Resolution Structure of the D347G D348G Mutant Structure of Sapporo Virus Rdrp Polymerase To be Published
6QWT	Sicinivirus 3Dpol RNA dependent RNA polymerase Descriptor: Genome polyprotein Authors: Dubankova, A, Boura, E. Deposit date: 2019-03-06 Release date: 2019-10-09 Last modified: 2019-11-06 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structures of kobuviral and siciniviral polymerases reveal conserved mechanism of picornaviral polymerase activation. J.Struct.Biol., 208, 2019
6R1I	Structure of porcine Aichi virus polymerase Descriptor: Genome polyprotein Authors: Dubankova, A, Boura, E. Deposit date: 2019-03-14 Release date: 2019-10-09 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.634 Å) Cite: Structures of kobuviral and siciniviral polymerases reveal conserved mechanism of picornaviral polymerase activation. J.Struct.Biol., 208, 2019
5I61	Crystal structure of the RNA-dependent RNA polymerase of a human picorbirnavirus Descriptor: Potential RNA-dependent RNA polymerase Authors: Collier, A.M, Guo, Y.R, Tao, Y.J. Deposit date: 2016-02-15 Release date: 2016-03-16 Last modified: 2019-12-11 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Initiation of RNA Polymerization and Polymerase Encapsidation by a Small dsRNA Virus. Plos Pathog., 12, 2016
6S2L	FMDV 3D polymerase crystallized in presence of (F)uridylylated VPg peptide Descriptor: GLYCEROL, Genome polyprotein Authors: Verdaguer, N, Ferrer-Orta, C. Deposit date: 2019-06-21 Release date: 2019-07-03 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.3 Å) Cite: (F)uridylylated Peptides Linked to VPg1 of Foot-and- Mouth Disease Virus (FMDV): Design, Synthesis and X-Ray Crystallography of the Complexes with FMDV RNA-Dependent RNA Polymerase. Molecules, 24, 2019
5I62	Crystal structure of the insertion loop deletion mutant of the RNA-dependent RNA polymerase of a human picorbirnavirus Descriptor: Potential RNA-dependent RNA polymerase Authors: Collier, A.M, Guo, Y.R, Tao, Y.J. Deposit date: 2016-02-15 Release date: 2016-03-16 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.001 Å) Cite: Initiation of RNA Polymerization and Polymerase Encapsidation by a Small dsRNA Virus. Plos Pathog., 12, 2016
5JXS	Mutant GC216/7AA of 3D polymerase from Foot-and-Mouth Disease Virus Descriptor: MAGNESIUM ION, RNA Primer, RNA Template, ... Authors: Verdaguer, N, Ferrer-Orta, C. Deposit date: 2016-05-13 Release date: 2016-06-01 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Both cis and trans Activities of Foot-and-Mouth Disease Virus 3D Polymerase Are Essential for Viral RNA Replication. J.Virol., 90, 2016

 

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