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6SIR
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BU of 6sir by Molmil
Crystal structure of the guanylate cyclase domain of RhGC from Catenaria anguillulae in complex with GTP
Descriptor: CALCIUM ION, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Butryn, A, Orville, A.M.
Deposit date:2019-08-10
Release date:2019-12-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular basis for GTP recognition by light-activated guanylate cyclase RhGC.
Febs J., 287, 2020
1AB8
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BU of 1ab8 by Molmil
RAT TYPE II ADENYLYL CYCLASE C2 DOMAIN/FORSKOLIN COMPLEX
Descriptor: ADENYLYL CYCLASE, FORSKOLIN
Authors:Zhang, G, Hurley, J.H.
Deposit date:1997-02-04
Release date:1997-05-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the adenylyl cyclase catalytic core.
Nature, 386, 1997
6YII
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BU of 6yii by Molmil
Crystal structure of a Class III adenylyl cyclase-like ATP-binding protein from Pseudomonas aeruginosa
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, MAGNESIUM ION, ...
Authors:Moniot, S, Steegborn, C.
Deposit date:2020-04-01
Release date:2020-06-17
Last modified:2020-07-15
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Crystal structure of a class III adenylyl cyclase-like ATP-binding protein from Pseudomonas aeruginosa.
J.Struct.Biol., 211, 2020
2BW7
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BU of 2bw7 by Molmil
A novel mechanism for adenylyl cyclase inhibition from the crystal structure of its complex with catechol estrogen
Descriptor: 2,3,17BETA-TRIHYDROXY-1,3,5(10)-ESTRATRIENE, ADENYLATE CYCLASE, CALCIUM ION, ...
Authors:Steegborn, C, Litvin, T.N, Hess, K.C, Capper, A.B, Taussig, R, Buck, J, Levin, L.R, Wu, H.
Deposit date:2005-07-12
Release date:2005-07-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A Novel Mechanism for Adenylyl Cyclase Inhibition from the Crystal Structure of its Complex with Catechol Estrogen
J.Biol.Chem., 280, 2005
3R5G
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BU of 3r5g by Molmil
Crystal structure of the adenylyl cyclase CyaB from P. aeruginosa
Descriptor: CyaB, GLYCEROL
Authors:Topal, H, Steegborn, C.
Deposit date:2011-03-18
Release date:2012-01-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal Structure and Regulation Mechanisms of the CyaB Adenylyl Cyclase from the Human Pathogen Pseudomonas aeruginosa.
J.Mol.Biol., 416, 2012
3MR7
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BU of 3mr7 by Molmil
Crystal Structure of Adenylate/Guanylate Cyclase/Hydrolase from Silicibacter pomeroyi
Descriptor: Adenylate/guanylate cyclase/hydrolase, alpha/beta fold family
Authors:Kim, Y, Li, H, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2010-04-28
Release date:2010-06-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of Adenylate/Guanylate Cyclase/Hydrolase from Silicibacter pomeroyi
To be Published
2W01
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BU of 2w01 by Molmil
Crystal structure of the guanylyl cyclase Cya2
Descriptor: ADENYLATE CYCLASE
Authors:Rauch, A, Leipelt, M, Russwurm, M, Steegborn, C.
Deposit date:2008-08-08
Release date:2008-09-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Crystal Structure of the Guanylyl Cyclase Cya2.
Proc.Natl.Acad.Sci.USA, 105, 2008
2WZ1
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BU of 2wz1 by Molmil
STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN SOLUBLE GUANYLATE CYCLASE 1 BETA 3.
Descriptor: 1,2-ETHANEDIOL, GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-1
Authors:Allerston, C.K, Cooper, C.D.O, Muniz, J, Pike, A.C.W, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Bountra, C, Gileadi, O.
Deposit date:2009-11-23
Release date:2009-12-01
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Crystal Structures of the Catalytic Domain of Human Soluble Guanylate Cyclase.
Plos One, 8, 2013
5IV4
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BU of 5iv4 by Molmil
Crystal structure of the human soluble adenylyl cyclase in complex with the allosteric inhibitor LRE1
Descriptor: 1,2-ETHANEDIOL, 6-chloro-N~4~-cyclopropyl-N~4~-[(thiophen-2-yl)methyl]pyrimidine-2,4-diamine, ACETATE ION, ...
Authors:Kleinboelting, S, Steegborn, C.
Deposit date:2016-03-18
Release date:2016-08-17
Last modified:2022-11-30
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclase.
Nat.Chem.Biol., 12, 2016
5IV3
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BU of 5iv3 by Molmil
Crystal structure of human soluble adenylyl cyclase in complex with alpha,beta-methyleneadenosine-5'-triphosphate and the allosteric inhibitor LRE1
Descriptor: 1,2-ETHANEDIOL, 6-chloro-N~4~-cyclopropyl-N~4~-[(thiophen-2-yl)methyl]pyrimidine-2,4-diamine, ACETATE ION, ...
Authors:Kleinboelting, S, Steegborn, C.
Deposit date:2016-03-18
Release date:2016-08-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclase.
Nat.Chem.Biol., 12, 2016
3UVJ
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BU of 3uvj by Molmil
Crystal structure of the catalytic domain of the heterodimeric human soluble guanylate cyclase 1.
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Guanylate cyclase soluble subunit alpha-3, ...
Authors:Allerston, C.K, Berridge, G, Chalk, R, Cooper, C.D.O, Savitsky, P, Vollmar, M, Arrowsmith, C.H, Weigelt, J, Edwards, A, Bountra, C, von Delft, F, Gileadi, O, Structural Genomics Consortium (SGC)
Deposit date:2011-11-30
Release date:2011-12-28
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Crystal structures of the catalytic domain of human soluble guanylate cyclase.
Plos One, 8, 2013
7YZ9
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BU of 7yz9 by Molmil
Structure of catalytic domain of Rv1625c bound to nanobody NB4
Descriptor: 3'-O-(N-METHYLANTHRANILOYL)-GUANOSINE-5'-TRIPHOSPHATE, Adenylate cyclase, GLYCEROL, ...
Authors:Khanppnavar, B, Mehta, V.J, Iype, T, Korkhov, V.M.
Deposit date:2022-02-19
Release date:2022-08-31
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structure of Mycobacterium tuberculosis Cya, an evolutionary ancestor of the mammalian membrane adenylyl cyclases.
Elife, 11, 2022
5O5K
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BU of 5o5k by Molmil
X-ray structure of a bacterial adenylyl cyclase soluble domain
Descriptor: 3'-O-(N-METHYLANTHRANILOYL)-GUANOSINE-5'-TRIPHOSPHATE, Adenylate cyclase, MANGANESE (II) ION, ...
Authors:Vercellino, I, Korkhov, V.M.
Deposit date:2017-06-02
Release date:2017-11-01
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Role of the nucleotidyl cyclase helical domain in catalytically active dimer formation.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5O5L
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BU of 5o5l by Molmil
X-ray structure of a bacterial adenylyl cyclase soluble domain, solved at cryogenic temperature
Descriptor: 3'-O-(N-METHYLANTHRANILOYL)-GUANOSINE-5'-TRIPHOSPHATE, Adenylate cyclase, MANGANESE (II) ION, ...
Authors:Vercellino, I, Korkhov, V.M.
Deposit date:2017-06-02
Release date:2017-11-01
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Role of the nucleotidyl cyclase helical domain in catalytically active dimer formation.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5OYH
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BU of 5oyh by Molmil
crystal structure of the catalytic core of a rhodopsin-guanylyl cyclase with converted specificity in complex with ATPalphaS
Descriptor: ADENOSINE-5'-SP-ALPHA-THIO-TRIPHOSPHATE, CALCIUM ION, GLYCEROL, ...
Authors:Broser, M, Scheib, U, Hegemann, P.
Deposit date:2017-09-09
Release date:2018-06-06
Method:X-RAY DIFFRACTION (2.249 Å)
Cite:Rhodopsin-cyclases for photocontrol of cGMP/cAMP and 2.3 angstrom structure of the adenylyl cyclase domain.
Nat Commun, 9, 2018
3ET6
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BU of 3et6 by Molmil
The crystal structure of the catalytic domain of a eukaryotic guanylate cyclase
Descriptor: PHOSPHATE ION, Soluble guanylyl cyclase beta
Authors:Winger, J.A, Derbyshire, E.R, Lamers, M.H, Marletta, M.A, Kuriyan, J.
Deposit date:2008-10-07
Release date:2008-10-14
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:The crystal structure of the catalytic domain of a eukaryotic guanylate cyclase.
Bmc Struct.Biol., 8, 2008
4WP8
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BU of 4wp8 by Molmil
Crystal structure of Adenylyl cyclase Ma1120 from Mycobacterium Avium in complex with 2'5'-DD-3'-ATP and Manganese ion
Descriptor: 2',5'-dideoxyadenosine 3'-(tetrahydrogen triphosphate), CHLORIDE ION, MANGANESE (II) ION, ...
Authors:Barathy, D.V, Bharambe, N.G, Suguna, K.
Deposit date:2014-10-17
Release date:2015-09-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Autoinhibitory mechanism and activity-related structural changes in a mycobacterial adenylyl cyclase
J.Struct.Biol., 190, 2015
4WP3
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BU of 4wp3 by Molmil
Crystal Structure of Adenylyl cyclase from Mycobacterium avium Ma1120 wild type
Descriptor: CHLORIDE ION, Ma1120
Authors:Barathy, D.V, Bharambe, N.G, Suguna, K.
Deposit date:2014-10-17
Release date:2015-09-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Autoinhibitory mechanism and activity-related structural changes in a mycobacterial adenylyl cyclase
J.Struct.Biol., 190, 2015
4USW
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BU of 4usw by Molmil
Crystal structure of human soluble Adenylyl Cyclase with ATP
Descriptor: ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, ADENYLATE CYCLASE TYPE 10, ...
Authors:Kleinboelting, S, Steegborn, C.
Deposit date:2014-07-13
Release date:2014-07-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural Analysis of Human Soluble Adenylyl Cyclase and Crystal Structures of its Nucleotide Complexes -Implications for Cyclase Catalysis and Evolution.
FEBS J., 281, 2014
4WPA
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BU of 4wpa by Molmil
Crystal structure of Adenylyl cyclase Ma1120 from Mycobacterium Avium bound to Pyrophosphate and Calcium
Descriptor: CALCIUM ION, Ma1120, PYROPHOSPHATE
Authors:Bharambe, N.G, Barathy, D.V, Suguna, K.
Deposit date:2014-10-17
Release date:2015-09-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Autoinhibitory mechanism and activity-related structural changes in a mycobacterial adenylyl cyclase
J.Struct.Biol., 190, 2015
4UST
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BU of 4ust by Molmil
Crystal structure of human soluble Adenylyl Cyclase with pyrophosphate resulting from soaking with GTP and Magnesium
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, ADENYLATE CYCLASE TYPE 10, ...
Authors:Kleinboelting, S, Steegborn, C.
Deposit date:2014-07-13
Release date:2014-07-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Analysis of Human Soluble Adenylyl Cyclase and Crystal Structures of its Nucleotide Complexes -Implications for Cyclase Catalysis and Evolution.
FEBS J., 281, 2014
4USU
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BU of 4usu by Molmil
Crystal structure of human soluble Adenylyl Cyclase in complex with alpha,beta-methyleneadenosine-5'-triphosphate
Descriptor: 1,2-ETHANEDIOL, ADENYLATE CYCLASE TYPE 10, CALCIUM ION, ...
Authors:Kleinboelting, S, Steegborn, C.
Deposit date:2014-07-13
Release date:2014-07-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural Analysis of Human Soluble Adenylyl Cyclase and Crystal Structures of its Nucleotide Complexes -Implications for Cyclase Catalysis and Evolution.
FEBS J., 281, 2014
4USV
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BU of 4usv by Molmil
Crystal structure of human soluble Adenylyl Cyclase with pyrophosphate resulting from soaking with ATP and Calcium
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, ADENYLATE CYCLASE TYPE 10, ...
Authors:Kleinboelting, S, Steegborn, C.
Deposit date:2014-07-13
Release date:2014-07-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Analysis of Human Soluble Adenylyl Cyclase and Crystal Structures of its Nucleotide Complexes -Implications for Cyclase Catalysis and Evolution.
FEBS J., 281, 2014
4WP9
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BU of 4wp9 by Molmil
Crystal structure of Adenylyl cyclase MA1120 from Mycobacterium Avium bound to 2'5'-DD-3'-ATP, Calcium and Magnesium ion
Descriptor: 2',5'-dideoxyadenosine 3'-(tetrahydrogen triphosphate), CALCIUM ION, MAGNESIUM ION, ...
Authors:Bharambe, N.G, Barathy, D.V, Suguna, K.
Deposit date:2014-10-17
Release date:2015-09-02
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.382 Å)
Cite:Autoinhibitory mechanism and activity-related structural changes in a mycobacterial adenylyl cyclase
J.Struct.Biol., 190, 2015
5D0G
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BU of 5d0g by Molmil
Crystal structure of triple mutant (KDA to EGY) of adenylyl cyclase Ma1120 from Mycobacterium avium in complex with GTP and calcium ion
Descriptor: CALCIUM ION, Cyclase, GUANOSINE-5'-TRIPHOSPHATE
Authors:Bharambe, N.G, Suguna, K.
Deposit date:2015-08-03
Release date:2016-08-10
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Substrate specificity determinants of class III nucleotidyl cyclases
Febs J., 283, 2016

217705

数据于2024-03-27公开中

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