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1BC8
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BU of 1bc8 by Molmil
STRUCTURES OF SAP-1 BOUND TO DNA SEQUENCES FROM THE E74 AND C-FOS PROMOTERS PROVIDE INSIGHTS INTO HOW ETS PROTEINS DISCRIMINATE BETWEEN RELATED DNA TARGETS
Descriptor: DNA (5'-D(*AP*AP*CP*TP*TP*CP*CP*GP*GP*T)-3'), DNA (5'-D(*TP*AP*CP*CP*GP*GP*AP*AP*GP*T)-3'), PROTEIN (SAP-1 ETS DOMAIN), ...
Authors:Mo, Y, Vaessen, B, Johnston, K, Marmorstein, R.
Deposit date:1998-05-05
Release date:1998-12-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Structures of SAP-1 bound to DNA targets from the E74 and c-fos promoters: insights into DNA sequence discrimination by Ets proteins.
Mol.Cell, 2, 1998
5W3G
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BU of 5w3g by Molmil
Solution Structure of ETS Transcription Factor PU.1
Descriptor: Transcription factor PU.1
Authors:Lau, D.K.W, Okon, M, McIntosh, L.P.
Deposit date:2017-06-07
Release date:2018-06-13
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Conserved protein dynamics within the ETS transcription factor family
To be published
3JTG
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BU of 3jtg by Molmil
Crystal structure of mouse Elf3 C-terminal DNA-binding domain in complex with type II TGF-beta receptor promoter DNA
Descriptor: DNA (5'-D(*CP*AP*AP*AP*CP*AP*GP*GP*AP*AP*AP*CP*TP*CP*CP*T)-3'), DNA (5'-D(*GP*AP*GP*GP*AP*GP*TP*TP*TP*CP*CP*TP*GP*TP*TP*T)-3'), ETS-related transcription factor Elf-3
Authors:Tahirov, T.H, Babayeva, N.D, Agarkar, V.B, Rizzino, A.
Deposit date:2009-09-11
Release date:2010-01-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of mouse Elf3 C-terminal DNA-binding domain in complex with type II TGF-beta receptor promoter DNA.
J.Mol.Biol., 397, 2010
2YPR
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BU of 2ypr by Molmil
Crystal structure of the DNA binding ETS domain of human protein FEV
Descriptor: GLYCEROL, PROTEIN FEV
Authors:Allerston, C.K, Cooper, C, Vollmar, M, Krojer, T, von Delft, F, Weigelt, J, Arrowsmith, C.H, Bountra, C, Edwards, A, Gileadi, O.
Deposit date:2012-10-31
Release date:2013-01-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Structures of the Ets Domains of Transcription Factors Etv1, Etv4, Etv5 and Fev: Determinants of DNA Binding and Redox Regulation by Disulfide Bond Formation.
J.Biol.Chem., 290, 2015
1WWX
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BU of 1wwx by Molmil
Solution structure of the ETS-domain of the Ets domain transcription factor
Descriptor: E74-like factor 5 ESE-2b
Authors:Goroncy, A, Kigawa, T, Koshiba, S, Kobayashi, N, Tochio, N, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-01-18
Release date:2005-07-18
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution structure of the ETS-domain of the Ets domain transcription factor
To be Published
1YO5
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BU of 1yo5 by Molmil
Analysis of the 2.0A crystal structure of the protein-DNA complex of human PDEF Ets domain bound to the prostate specific antigen regulatory site
Descriptor: Enhancer site of Prostate Specific Antigen Promoter Region, SAM pointed domain containing ets transcription factor
Authors:Wang, Y, Feng, L, Said, M, Balderman, S, Fayazi, Z, Liu, Y, Ghosh, D, Gulick, A.M.
Deposit date:2005-01-26
Release date:2005-05-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Analysis of the 2.0 A Crystal Structure of the Protein-DNA Complex of the Human PDEF Ets Domain Bound to the Prostate Specific Antigen Regulatory Site
Biochemistry, 44, 2005
3MFK
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BU of 3mfk by Molmil
Ets1 complex with stromelysin-1 promoter DNA
Descriptor: Protein C-ets-1, stromelysin-1 promoter DNA
Authors:Babayeva, N.D, Mino, K, Tahirov, T.H.
Deposit date:2010-04-02
Release date:2010-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis of Ets1 cooperative binding to palindromic sequences on stromelysin-1 promoter DNA.
Cell Cycle, 9, 2010
1BC7
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BU of 1bc7 by Molmil
SERUM RESPONSE FACTOR ACCESSORY PROTEIN 1A (SAP-1)/DNA COMPLEX
Descriptor: DNA (5'-D(*CP*AP*CP*AP*TP*CP*CP*TP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*AP*GP*GP*AP*TP*GP*TP*G)-3'), PROTEIN (ETS-DOMAIN PROTEIN)
Authors:Mo, Y, Vaessen, B, Johnston, K, Marmorstein, R.
Deposit date:1998-05-05
Release date:1999-01-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structures of SAP-1 bound to DNA targets from the E74 and c-fos promoters: insights into DNA sequence discrimination by Ets proteins.
Mol.Cell, 2, 1998
6DA1
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BU of 6da1 by Molmil
ETS1 in complex with synthetic SRR mimic
Descriptor: Protein C-ets-1, SULFATE ION, serine-rich region (SRR) peptide
Authors:Perez-Borrajero, C, Okon, M, Lin, C.S, Scheu, K, Murphy, M.E.P, Graves, B.J, McIntosh, L.P.
Deposit date:2018-05-01
Release date:2019-01-16
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.000127 Å)
Cite:The Biophysical Basis for Phosphorylation-Enhanced DNA-Binding Autoinhibition of the ETS1 Transcription Factor.
J. Mol. Biol., 431, 2019
1DUX
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BU of 1dux by Molmil
ELK-1/DNA STRUCTURE REVEALS HOW RESIDUES DISTAL FROM DNA-BINDING SURFACE AFFECT DNA-RECOGNITION
Descriptor: DNA (5'-D(*AP*CP*AP*CP*TP*TP*CP*CP*GP*GP*TP*CP*A)-3'), DNA (5'-D(*TP*GP*AP*CP*CP*GP*GP*AP*AP*GP*TP*GP*T)-3'), ETS-DOMAIN PROTEIN ELK-1
Authors:Mo, Y, Vaessen, B, Johnston, K, Marmorstein, R.
Deposit date:2000-01-19
Release date:2000-04-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the elk-1-DNA complex reveals how DNA-distal residues affect ETS domain recognition of DNA.
Nat.Struct.Biol., 7, 2000
6DAT
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BU of 6dat by Molmil
ETS1 in complex with synthetic SRR mimic
Descriptor: Protein C-ets-1, SULFATE ION, serine-rich region (SRR) peptide
Authors:Perez-Borrajero, C, Okon, M, Lin, C.S, Scheu, K, Murphy, M.E.P, Graves, B.J, McIntosh, L.P.
Deposit date:2018-05-02
Release date:2019-01-16
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.35002637 Å)
Cite:The Biophysical Basis for Phosphorylation-Enhanced DNA-Binding Autoinhibition of the ETS1 Transcription Factor.
J. Mol. Biol., 431, 2019
5E8G
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BU of 5e8g by Molmil
Crystal structure of the DNA binding domain of human transcription factor FLI1
Descriptor: COBALT (II) ION, Friend leukemia integration 1 transcription factor
Authors:Hou, C, Tsodikov, O.V.
Deposit date:2015-10-14
Release date:2015-12-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Basis for Dimerization and DNA Binding of Transcription Factor FLI1.
Biochemistry, 54, 2015
4UNO
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BU of 4uno by Molmil
Crystal structure of the ETS domain of human ETV5 in complex with DNA
Descriptor: 5'-D(*AP*CP*CP*GP*GP*AP*AP*GP*TP*GP)-3', 5'-D(*AP*CP*TP*TP*CP*CP*GP*GP*TP*CP)-3', CALCIUM ION, ...
Authors:Newman, J.A, Aitkenhead, H, Cooper, C.D.O, Pinkas, D.M, Shrestha, L, Burgess-Brown, N, Kopec, J, Fitzpatrick, F, Tallant, C, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A, Gileadi, O.
Deposit date:2014-05-29
Release date:2014-06-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structures of the Ets Domains of Transcription Factors Etv1, Etv4, Etv5 and Fev: Determinants of DNA Binding and Redox Regulation by Disulfide Bond Formation.
J.Biol.Chem., 290, 2015
5E8I
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BU of 5e8i by Molmil
Crystal structure of the DNA binding domain of human transcription factor FLI1 in complex with a 10-mer DNA ACCGGAAGTG
Descriptor: CALCIUM ION, DNA (5'-D(*AP*CP*CP*GP*GP*AP*AP*GP*TP*G)-3'), DNA (5'-D(*CP*AP*CP*TP*TP*CP*CP*GP*GP*T)-3'), ...
Authors:Hou, C, Tsodikov, O.V.
Deposit date:2015-10-14
Release date:2015-12-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Structural Basis for Dimerization and DNA Binding of Transcription Factor FLI1.
Biochemistry, 54, 2015
4UUV
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BU of 4uuv by Molmil
Structure of the DNA binding ETS domain of human ETV4 in complex with DNA
Descriptor: 5'-D(*AP*CP*CP*GP*GP*AP*AP*GP*TP*GP)-3', 5'-D(*AP*CP*TP*TP*CP*CP*GP*GP*TP*CP)-3', ETS TRANSLOCATION VARIANT 4
Authors:Newman, J.A, Cooper, C.D.O, Kopec, J, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O.
Deposit date:2014-07-31
Release date:2014-08-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of the Ets Domains of Transcription Factors Etv1, Etv4, Etv5 and Fev: Determinants of DNA Binding and Redox Regulation by Disulfide Bond Formation.
J.Biol.Chem., 290, 2015
1PUE
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BU of 1pue by Molmil
PU.1 ETS DOMAIN-DNA COMPLEX
Descriptor: DNA (5'-D(*AP*AP*AP*AP*AP*GP*GP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*CP*CP*TP*TP*TP*T)-3'), PROTEIN (TRANSCRIPTION FACTOR PU.1 (TF PU.1))
Authors:Kodandapani, R, Pio, F, Ni, C.Z, Piccialli, G, Klemsz, M, McKercher, S, Maki, R.A, Ely, K.R.
Deposit date:1996-07-08
Release date:1997-02-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A new pattern for helix-turn-helix recognition revealed by the PU.1 ETS-domain-DNA complex.
Nature, 380, 1996
1FLI
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BU of 1fli by Molmil
DNA-BINDING DOMAIN OF FLI-1
Descriptor: FLI-1
Authors:Liang, H, Mao, X, Olejniczak, E.T, Nettesheim, D.G, Yu, L, Meadows, R.P, Thompson, C.B, Fesik, S.W.
Deposit date:1994-09-15
Release date:1995-09-15
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of the ets domain of Fli-1 when bound to DNA.
Nat.Struct.Biol., 1, 1994
7JSA
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BU of 7jsa by Molmil
Crystal structure of the DNA binding domain of human transcription factor ERF in the reduced form, in complex with double-stranded DNA ACCGGAAGTG
Descriptor: DNA (5'-D(*AP*CP*CP*GP*GP*AP*AP*GP*TP*G)-3'), DNA (5'-D(*CP*AP*CP*TP*TP*CP*CP*GP*GP*T)-3'), ETS domain-containing transcription factor ERF
Authors:Hou, C, Tsodikov, O.V.
Deposit date:2020-08-14
Release date:2020-11-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural Insight into the DNA Binding Function of Transcription Factor ERF.
Biochemistry, 2020
7JSL
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BU of 7jsl by Molmil
Crystal structure of the DNA binding domain of human transcription factor ERF in the oxidized form, in complex with double-stranded DNA ACCGGAAGTG
Descriptor: DNA (5'-D(*AP*CP*CP*GP*GP*AP*AP*GP*TP*G)-3'), DNA (5'-D(*CP*AP*CP*TP*TP*CP*CP*GP*GP*T)-3'), ETS domain-containing transcription factor ERF
Authors:Hou, C, Tsodikov, O.V.
Deposit date:2020-08-14
Release date:2020-11-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (4.51 Å)
Cite:Structural Insight into the DNA Binding Function of Transcription Factor ERF.
Biochemistry, 2020
1R36
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BU of 1r36 by Molmil
NMR-based structure of autoinhibited murine Ets-1 deltaN301
Descriptor: C-ets-1 protein
Authors:Lee, G.M, Donaldson, L.W, Pufall, M.A, Kang, H.-S, Pot, I, Graves, B.J, McIntosh, L.P.
Deposit date:2003-09-30
Release date:2004-11-09
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:The Structural and Dynamic Basis of Ets-1 DNA Binding Autoinhibition
J.Biol.Chem., 280, 2005
2DAO
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BU of 2dao by Molmil
Solution structure of ETS domain Transcriptional factor ETV6 protein
Descriptor: Transcription factor ETV6
Authors:Niraula, T.N, Sasagawa, A, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-12-14
Release date:2006-12-12
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of ETS domain Transcriptional factor ETV6 protein
To be Published
3RI4
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BU of 3ri4 by Molmil
Ets1 cooperative binding to widely separated sites on promoter DNA
Descriptor: Isoform Ets-1 p27 of Protein C-ets-1, TCR alpha promoter DNA
Authors:Babayeva, N.D, Mino, K, Tahirov, T.H.
Deposit date:2011-04-12
Release date:2012-04-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis of ets1 cooperative binding to widely separated sites on promoter DNA.
Plos One, 7, 2012
2LF8
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BU of 2lf8 by Molmil
Intramolecular regulation of the ETS Domain within ETV6 sequence R335 to R458
Descriptor: Transcription factor ETV6
Authors:Coyne III, H, Green, S.M, Graves, B.J, Mcintosh, L.P.
Deposit date:2011-06-28
Release date:2012-05-23
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Autoinhibition of ETV6 (TEL) DNA Binding: Appended Helices Sterically Block the ETS Domain.
J.Mol.Biol., 421, 2012
2LF7
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BU of 2lf7 by Molmil
Intramolecular regulation of the ETS Domain within ETV6 sequence R335 to Q436
Descriptor: Transcription factor ETV6
Authors:Coyne III, H, Green, S.M, Graves, B.J, Mcintosh, L.P.
Deposit date:2011-06-28
Release date:2012-05-23
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Autoinhibition of ETV6 (TEL) DNA Binding: Appended Helices Sterically Block the ETS Domain.
J.Mol.Biol., 421, 2012
5YBC
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BU of 5ybc by Molmil
X-ray structure of native ETS-domain domain of Ergp55
Descriptor: GLYCEROL, Transcriptional regulator ERG
Authors:Saxena, A.K, Gangwar, S.P.
Deposit date:2017-09-04
Release date:2018-09-19
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Comparative structure analysis of the ETSi domain of ERG3 and its complex with the E74 promoter DNA sequence
Acta Crystallogr F Struct Biol Commun, 74, 2018

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数据于2024-03-27公开中

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