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8QCI
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BU of 8qci by Molmil
FCGBP D10 Assembly Segment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ...
Authors:Yeshaya, N, Fass, D.
Deposit date:2023-08-27
Release date:2024-03-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:VWD domain stabilization by autocatalytic Asp-Pro cleavage.
Protein Sci., 33, 2024
7QCN
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BU of 7qcn by Molmil
Structure of the MUCIN-2 Cterminal domains: vWCN to TIL domains with a C2 symmetry
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Mucin-2, ...
Authors:Gallego, P, Hansson, G.C.
Deposit date:2021-11-24
Release date:2023-03-08
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:The intestinal MUC2 mucin C-terminus is stabilized by an extra disulfide bond in comparison to von Willebrand factor and other gel-forming mucins.
Nat Commun, 14, 2023
7QCU
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BU of 7qcu by Molmil
Structure of the MUCIN-2 Cterminal domains partially deglycosylated.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Mucin-2, ...
Authors:Gallego, P, Hansson, G.C.
Deposit date:2021-11-25
Release date:2023-03-08
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:The intestinal MUC2 mucin C-terminus is stabilized by an extra disulfide bond in comparison to von Willebrand factor and other gel-forming mucins.
Nat Commun, 14, 2023
7QCL
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BU of 7qcl by Molmil
Structure of the MUCIN-2 Cterminal domains
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Mucin-2, ...
Authors:Gallego, P, Hansson, G.C.
Deposit date:2021-11-24
Release date:2023-03-08
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:The intestinal MUC2 mucin C-terminus is stabilized by an extra disulfide bond in comparison to von Willebrand factor and other gel-forming mucins.
Nat Commun, 14, 2023
7PRL
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BU of 7prl by Molmil
MUC2 D1 with Cu(II)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, GLYCEROL, ...
Authors:Reznik, N, Fass, D.
Deposit date:2021-09-22
Release date:2022-10-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Intestinal mucin is a chaperone of multivalent copper.
Cell, 185, 2022
7ZWH
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BU of 7zwh by Molmil
VWF Tubules of D1D2 and D'D3A1 domains
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Javitt, G, Fass, D.
Deposit date:2022-05-19
Release date:2022-07-13
Last modified:2023-01-11
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Assembly of von Willebrand factor tubules with in vivo helical parameters requires A1 domain insertion.
Blood, 140, 2022
8D3C
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BU of 8d3c by Molmil
VWF tubule derived from monomeric D1-A1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand factor
Authors:Anderson, J.R, Li, J, Springer, T.A, Brown, A.
Deposit date:2022-06-01
Release date:2022-07-06
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structures of VWF tubules before and after concatemerization reveal a mechanism of disulfide bond exchange.
Blood, 140, 2022
8D3D
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BU of 8d3d by Molmil
VWF tubule derived from dimeric D1-A1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand factor
Authors:Anderson, J.R, Li, J, Springer, T.A, Brown, A.
Deposit date:2022-06-01
Release date:2022-07-06
Last modified:2022-10-05
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structures of VWF tubules before and after concatemerization reveal a mechanism of disulfide bond exchange.
Blood, 140, 2022
7WPQ
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BU of 7wpq by Molmil
Cryo-EM structure of VWF D'D3 dimer complexed with D1D2 at 3.27 angstron resolution (2 units)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand antigen 2, ...
Authors:Zeng, J.W, Shu, Z.M, Zhou, A.W.
Deposit date:2022-01-24
Release date:2022-05-25
Last modified:2022-06-15
Method:ELECTRON MICROSCOPY (3.267 Å)
Cite:Structural basis of von Willebrand factor multimerization and tubular storage.
Blood, 139, 2022
7WPR
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BU of 7wpr by Molmil
VWF D'D3 dimer complexed with D1D2 at 4.39 angstron resolution(VWF tube)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand antigen 2, ...
Authors:Zeng, J.W, Shu, Z.M, Zhou, A.W.
Deposit date:2022-01-24
Release date:2022-05-25
Last modified:2022-06-15
Method:ELECTRON MICROSCOPY (4.39 Å)
Cite:Structural basis of von Willebrand factor multimerization and tubular storage.
Blood, 139, 2022
7WPS
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BU of 7wps by Molmil
Cryo-EM structure of VWF D'D3 dimer complexed with D1D2 at 4.3 angstron resolution (7 units)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand antigen 2, ...
Authors:Zeng, J.W, Shu, Z.M, Zhou, A.W.
Deposit date:2022-01-24
Release date:2022-05-25
Last modified:2022-06-15
Method:ELECTRON MICROSCOPY (4.32 Å)
Cite:Structural basis of von Willebrand factor multimerization and tubular storage.
Blood, 139, 2022
7WN3
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BU of 7wn3 by Molmil
Cryo-EM structure of VWF D'D3 dimer (2M mutant) complexed with D1D2 at 3.29 angstron resolution (2 units)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand antigen 2, ...
Authors:Zeng, J.W, Shu, Z.M, Zhou, A.W.
Deposit date:2022-01-17
Release date:2022-05-25
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Structural mechanism of VWF D'D3 dimer formation.
Cell Discov, 8, 2022
7WPP
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BU of 7wpp by Molmil
Cryo-EM structure of VWF D'D3 dimer complexed with D1D2 at 2.85 angstron resolution (1 unit)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand antigen 2, ...
Authors:Zeng, J.W, Shu, Z.M, Zhou, A.W.
Deposit date:2022-01-24
Release date:2022-05-25
Last modified:2022-06-15
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Structural basis of von Willebrand factor multimerization and tubular storage.
Blood, 139, 2022
7WQT
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BU of 7wqt by Molmil
Cryo-EM structure of VWF D'D3 dimer complexed with D1D2 at 4.3 angstron resolution (VWF tube)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand antigen 2, ...
Authors:Zeng, J.W, Shu, Z.M, Zhou, A.W.
Deposit date:2022-01-26
Release date:2022-05-25
Last modified:2022-06-15
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural basis of von Willebrand factor multimerization and tubular storage.
Blood, 139, 2022
7WN4
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BU of 7wn4 by Molmil
Cryo-EM structure of VWF D'D3 dimer (wild type) complexed with D1D2 at 3.4 angstron resolution (1 unit)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand antigen 2, ...
Authors:Zeng, J.W, Shu, Z.M, Zhou, A.W.
Deposit date:2022-01-17
Release date:2022-05-18
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural mechanism of VWF D'D3 dimer formation.
Cell Discov, 8, 2022
7WN6
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BU of 7wn6 by Molmil
Cryo-EM structure of VWF D'D3 dimer (R1136M/E1143M mutant) complexed with D1D2 at 3.29 angstron resolution (2 units)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, von Willebrand antigen 2, ...
Authors:Zeng, J.W, Shu, Z.M, Zhou, A.W.
Deposit date:2022-01-17
Release date:2022-05-18
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Structural mechanism of VWF D'D3 dimer formation.
Cell Discov, 8, 2022
7PMV
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BU of 7pmv by Molmil
VWF Tubules of D1D2D'D3 domains
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Javitt, G, Fass, D.
Deposit date:2021-09-02
Release date:2022-02-23
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Helical self-assembly of a mucin segment suggests an evolutionary origin for von Willebrand factor tubules.
Proc.Natl.Acad.Sci.USA, 119, 2022
7PNF
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BU of 7pnf by Molmil
VWF Tubules of D1D2D'D3 domains
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Javitt, G, Fass, D.
Deposit date:2021-09-06
Release date:2022-02-23
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (4.35 Å)
Cite:Helical self-assembly of a mucin segment suggests an evolutionary origin for von Willebrand factor tubules.
Proc.Natl.Acad.Sci.USA, 119, 2022
7PP6
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BU of 7pp6 by Molmil
MUC2 Tubules of D1D2D3 domains
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Javitt, G, Fass, D.
Deposit date:2021-09-13
Release date:2022-02-16
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Helical self-assembly of a mucin segment suggests an evolutionary origin for von Willebrand factor tubules.
Proc.Natl.Acad.Sci.USA, 119, 2022
7POV
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BU of 7pov by Molmil
MUC2 Tubules of D1D2D3 domains
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Javitt, G, Fass, D.
Deposit date:2021-09-10
Release date:2022-02-16
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Helical self-assembly of a mucin segment suggests an evolutionary origin for von Willebrand factor tubules.
Proc.Natl.Acad.Sci.USA, 119, 2022
7KWO
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BU of 7kwo by Molmil
rFVIIIFc-VWF-XTEN (BIVV001)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COPPER (II) ION, ...
Authors:Fuller, J.R, Batchelor, J.D.
Deposit date:2020-12-01
Release date:2021-03-03
Last modified:2021-06-09
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Molecular determinants of the factor VIII/von Willebrand factor complex revealed by BIVV001 cryo-electron microscopy.
Blood, 137, 2021
7A5O
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BU of 7a5o by Molmil
Human MUC2 AAs 21-1397
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Javitt, G, Khmelnitsky, L, Albert, L, Elad, N, Ilani, T, Diskin, R, Fass, D.
Deposit date:2020-08-21
Release date:2020-10-21
Last modified:2020-11-11
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Assembly Mechanism of Mucin and von Willebrand Factor Polymers.
Cell, 183, 2020
6TM2
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BU of 6tm2 by Molmil
Human MUC2 AAs 21-1397
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Javitt, G, Khmelnitsky, L, Albert, L, Elad, N, Ilani, T, Diskin, R, Fass, D.
Deposit date:2019-12-03
Release date:2020-10-21
Last modified:2020-11-11
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Assembly Mechanism of Mucin and von Willebrand Factor Polymers.
Cell, 183, 2020
6RBF
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BU of 6rbf by Molmil
Mucin 2 D3 domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ...
Authors:Javitt, G, Fass, D.
Deposit date:2019-04-10
Release date:2019-08-14
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.704 Å)
Cite:Intestinal Gel-Forming Mucins Polymerize by Disulfide-Mediated Dimerization of D3 Domains.
J.Mol.Biol., 431, 2019
6N29
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BU of 6n29 by Molmil
Crystal structure of monomeric von Willebrand Factor D`D3 assembly
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Dong, X, Arndt, J.W, Springer, T.A.
Deposit date:2018-11-12
Release date:2019-01-23
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The von Willebrand factor D'D3 assembly and structural principles for factor VIII binding and concatemer biogenesis.
Blood, 133, 2019

 

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数据于2024-03-27公开中

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