Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

2D3D
DownloadVisualize
BU of 2d3d by Molmil
crystal structure of the RNA binding SAM domain of saccharomyces cerevisiae Vts1
Descriptor: CALCIUM ION, Vts1 protein
Authors:Aviv, T, Amborski, A.N, Zhao, X.S, Kwan, J.J, Johnson, P.E, Sicheri, F, Donaldson, L.W.
Deposit date:2005-09-27
Release date:2006-02-14
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The NMR and X-ray Structures of the Saccharomyces cerevisiae Vts1 SAM Domain Define a Surface for the Recognition of RNA Hairpins
J.Mol.Biol., 356, 2006
2DKY
DownloadVisualize
BU of 2dky by Molmil
Solution structure of the SAM-domain of Rho-GTPase-activating protein 7
Descriptor: Rho-GTPase-activating protein 7
Authors:Goroncy, A.K, Sato, M, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-04-14
Release date:2007-04-24
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of the SAM-domain of Rho-GTPase-activating protein 7
To be Published
2DL0
DownloadVisualize
BU of 2dl0 by Molmil
Solution structure of the SAM-domain of the SAM and SH3 domain containing protein 1
Descriptor: SAM and SH3 domain-containing protein 1
Authors:Goroncy, A.K, Sato, M, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-04-14
Release date:2006-10-14
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of the SAM-domain of the SAM and SH3 domain containing protein 1
To be Published
2E8O
DownloadVisualize
BU of 2e8o by Molmil
Solution structure of the N-terminal SAM-domain of the SAM domain and HD domain containing protein 1 (Dendritic cell-derived IFNG-induced protein) (DCIP) (Monocyte protein 5) (MOP-5)
Descriptor: SAM domain and HD domain-containing protein 1
Authors:Goroncy, A.K, Tochio, N, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-01-22
Release date:2007-07-24
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of the N-terminal SAM-domain of the SAM domain and HD domain containing protein 1 (Dendritic cell-derived IFNG-induced protein) (DCIP) (Monocyte protein 5) (MOP-5)
To be Published
2EAP
DownloadVisualize
BU of 2eap by Molmil
Solution structure of the N-terminal SAM-domain of human lymphocyte cytosolic protein 2
Descriptor: Lymphocyte cytosolic protein 2
Authors:Goroncy, A.K, Sato, M, Tochio, N, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-01-31
Release date:2008-02-05
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of the N-terminal SAM-domain of human lymphocyte cytosolic protein 2
To be Published
2ESE
DownloadVisualize
BU of 2ese by Molmil
Structure of the SAM domain of Vts1p in complex with RNA
Descriptor: 5'-R(*GP*GP*AP*GP*AP*GP*GP*CP*UP*CP*UP*GP*GP*CP*AP*GP*CP*UP*UP*UP*UP*CP*C)-3', Vts1p
Authors:Allain, F.H.T.
Deposit date:2005-10-26
Release date:2006-01-24
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Shape-specific recognition in the structure of the Vts1p SAM domain with RNA.
Nat.Struct.Mol.Biol., 13, 2006
2ES6
DownloadVisualize
BU of 2es6 by Molmil
Structure of the SAM domain of Vts1p
Descriptor: Vts1p
Authors:Allain, F.H.T.
Deposit date:2005-10-25
Release date:2006-01-24
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Shape-specific recognition in the structure of the Vts1p SAM domain with RNA.
Nat.Struct.Mol.Biol., 13, 2006
2F8K
DownloadVisualize
BU of 2f8k by Molmil
Sequence specific recognition of RNA hairpins by the SAM domain of Vts1
Descriptor: 5'-R(*UP*AP*AP*UP*CP*UP*UP*UP*GP*AP*CP*AP*GP*AP*UP*U)-3', Protein VTS1
Authors:Aviv, T, Lin, Z, Ben-Ari, G, Smibert, C.A, Sicheri, F.
Deposit date:2005-12-02
Release date:2006-01-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Sequence-specific recognition of RNA hairpins by the SAM domain of Vts1p.
Nat.Struct.Mol.Biol., 13, 2006
2FE9
DownloadVisualize
BU of 2fe9 by Molmil
Solution structure of the Vts1 SAM domain in the presence of RNA
Descriptor: Protein VTS1
Authors:Edwards, T.A, Butterwick, J.A, Palmer, A.G, Aggarwal, A.K.
Deposit date:2005-12-15
Release date:2006-01-24
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution Structure of the Vts1 SAM Domain in the Presence of RNA.
J.Mol.Biol., 356, 2006
2GLE
DownloadVisualize
BU of 2gle by Molmil
Solution structure of neurabin SAM domain
Descriptor: Neurabin-1
Authors:Ju, T, Hudak, J, Peti, W.
Deposit date:2006-04-04
Release date:2007-03-13
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Structural characterization of the neurabin SAM domain
TO BE PUBLISHED
2GYT
DownloadVisualize
BU of 2gyt by Molmil
Solution structure of the SAM (sterile alpha motif) domain of DLC1 (deleted in liver cancer 1)
Descriptor: Deleted in liver cancer 1 protein, isoform 2
Authors:Yang, S.
Deposit date:2006-05-10
Release date:2007-04-24
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:The SAM domain of the RhoGAP DLC1 binds EF1A1 to regulate cell migration
J.Cell.Sci., 122, 2009
2H80
DownloadVisualize
BU of 2h80 by Molmil
NMR structures of SAM domain of Deleted in Liver Cancer 2 (DLC2)
Descriptor: StAR-related lipid transfer protein 13
Authors:Li, H.Y, Fung, K.L, Jin, D.Y, Chung, S.S, Ko, B.C, Sun, H.Z.
Deposit date:2006-06-06
Release date:2007-05-15
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structures, dynamics, and lipid-binding of the sterile alpha-motif domain of the deleted in liver cancer 2
Proteins, 67, 2007
2JW2
DownloadVisualize
BU of 2jw2 by Molmil
Validation of inter-helical orientation of the steril-alpha-motif of human deleted in liver cancer 2 by residual dipolar couplings
Descriptor: StAR-related lipid transfer protein 13
Authors:Li, H, Sze, K, Fung, K.
Deposit date:2007-10-03
Release date:2008-10-21
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Validation of inter-helical orientation of the steril-alpha-motif of human deleted in liver cancer 2 by residual dipolar couplings
To be Published
2KG5
DownloadVisualize
BU of 2kg5 by Molmil
NMR Solution structure of ARAP3-SAM
Descriptor: Arf-GAP, Rho-GAP domain, ANK repeat and PH domain-containing protein 3
Authors:Leone, M, Pellecchia, M.
Deposit date:2009-03-05
Release date:2009-11-17
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:The Sam domain of the lipid phosphatase Ship2 adopts a common model to interact with Arap3-Sam and EphA2-Sam.
Bmc Struct.Biol., 9, 2009
2KAP
DownloadVisualize
BU of 2kap by Molmil
Solution structure of DLC1-SAM
Descriptor: Rho GTPase-activating protein 7
Authors:Yang, S, Yang, D.
Deposit date:2008-11-12
Release date:2009-10-20
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Characterization of DLC1-SAM equilibrium unfolding at the amino acid residue level
Biochemistry, 48, 2009
2K60
DownloadVisualize
BU of 2k60 by Molmil
NMR structure of calcium-loaded STIM1 EF-SAM
Descriptor: CALCIUM ION, PROTEIN (Stromal interaction molecule 1)
Authors:Stathopulos, P.B, Ikura, M.
Deposit date:2008-07-02
Release date:2008-10-07
Last modified:2013-07-24
Method:SOLUTION NMR
Cite:Structural and mechanistic insights into STIM1-mediated initiation of store-operated calcium entry.
Cell(Cambridge,Mass.), 135, 2008
2L5Y
DownloadVisualize
BU of 2l5y by Molmil
NMR structure of calcium-loaded STIM2 EF-SAM.
Descriptor: CALCIUM ION, Stromal interaction molecule 2
Authors:Zheng, L, Stathopulos, P.B, Ikura, M.
Deposit date:2010-11-09
Release date:2011-01-19
Last modified:2020-02-05
Method:SOLUTION NMR
Cite:Auto-inhibitory role of the EF-SAM domain of STIM proteins in store-operated calcium entry.
Proc.Natl.Acad.Sci.USA, 108, 2011
7CM6
DownloadVisualize
BU of 7cm6 by Molmil
NAD+-bound Sarm1 in the self-inhibited state
Descriptor: NAD(+) hydrolase SARM1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Zhang, Z, Jiang, Y.
Deposit date:2020-07-25
Release date:2020-10-21
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3 Å)
Cite:The NAD + -mediated self-inhibition mechanism of pro-neurodegenerative SARM1.
Nature, 588, 2020
3FXX
DownloadVisualize
BU of 3fxx by Molmil
Human EphA3 Kinase and Juxtamembrane Region Bound to Substrate KQWDNYE[pTyr]IW
Descriptor: Ephrin type-A receptor 3, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Davis, T, Walker, J.R, Mackenzie, F, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
Deposit date:2009-01-21
Release date:2009-02-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural recognition of an optimized substrate for the ephrin family of receptor tyrosine kinases.
Febs J., 276, 2009
7KNQ
DownloadVisualize
BU of 7knq by Molmil
SARM1 Octamer
Descriptor: NAD(+) hydrolase SARM1
Authors:Shen, C, Wu, H.
Deposit date:2020-11-05
Release date:2021-11-17
Last modified:2022-06-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Multiple domain interfaces mediate SARM1 autoinhibition.
Proc.Natl.Acad.Sci.USA, 118, 2021
7LD0
DownloadVisualize
BU of 7ld0 by Molmil
Cryo-EM structure of ligand-free Human SARM1
Descriptor: NAD(+) hydrolase SARM1
Authors:Nanson, J.D, Gu, W, Luo, Z, Jia, X, Landsberg, M.J, Kobe, B, Ve, T.
Deposit date:2021-01-12
Release date:2021-03-10
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:SARM1 is a metabolic sensor activated by an increased NMN/NAD + ratio to trigger axon degeneration.
Neuron, 109, 2021
6WPK
DownloadVisualize
BU of 6wpk by Molmil
SARM1 Autoinhibited Conformation
Descriptor: NAD(+) hydrolase SARM1
Authors:Xie, T, Bratkowski, M, Bai, X, Sambashivan, S.
Deposit date:2020-04-27
Release date:2020-08-12
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural and Mechanistic Regulation of the Prodegenerative NAD Hydrolase SARM1
Cell Rep, 32, 2020
7DJT
DownloadVisualize
BU of 7djt by Molmil
Human SARM1 inhibitory state bounded with inhibitor dHNN
Descriptor: NAD(+) hydrolase SARM1, O3-methyl O5-(2-methylpropyl) 2,6-dimethyl-4-[2-(oxidanylamino)phenyl]pyridine-3,5-dicarboxylate
Authors:Cai, Y, Zhang, H.
Deposit date:2020-11-21
Release date:2021-05-19
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Permeant fluorescent probes visualize the activation of SARM1 and uncover an anti-neurodegenerative drug candidate.
Elife, 10, 2021
4TWO
DownloadVisualize
BU of 4two by Molmil
Human EphA3 Kinase domain in complex with compound 164
Descriptor: 5-{[3-carbamoyl-4-(3,4-dimethylphenyl)-5-methylthiophen-2-yl]amino}-5-oxopentanoic acid, Ephrin type-A receptor 3
Authors:Dong, J, Caflisch, A.
Deposit date:2014-07-01
Release date:2015-05-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.047 Å)
Cite:Structural Analysis of the Binding of Type I, I1/2, and II Inhibitors to Eph Tyrosine Kinases.
Acs Med.Chem.Lett., 6, 2015
8P2L
DownloadVisualize
BU of 8p2l by Molmil
A CHIMERA construct containing human SARM1 ARM and SAM domains and C. elegans TIR domain.
Descriptor: NAD(+) hydrolase SARM1,NAD(+) hydrolase tir-1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Isupov, M.N, Opatowsky, Y.
Deposit date:2023-05-16
Release date:2023-09-06
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:Structure-function analysis of ceTIR-1/hSARM1 explains the lack of Wallerian axonal degeneration in C. elegans.
Cell Rep, 42, 2023

217705

数据于2024-03-27公开中

PDB statisticsPDBj update infoContact PDBjnumon