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4R32
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BU of 4r32 by Molmil
Crystal Structure Analysis of Pyk2 and Paxillin LD motifs
Descriptor: Paxillin, Protein-tyrosine kinase 2-beta
Authors:Vanarotti, M, Miller, D.J, Guibao, C.D, Nourse, A, Zheng, J.J.
Deposit date:2014-08-13
Release date:2014-09-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.505 Å)
Cite:Structural and Mechanistic Insights into the Interaction between Pyk2 and Paxillin LD Motifs.
J.Mol.Biol., 426, 2014
6PW8
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BU of 6pw8 by Molmil
Hydrocarbon-Stapled Paxillin Peptide Bound to the Focal Adhesion Targeting (FAT) Domain of the Focal Adhesion Kinase (FAK)
Descriptor: CHLORIDE ION, Focal adhesion kinase 1, SP3, ...
Authors:Thifault, D.G, Fromme, P, Martin-Garcia, J.M.
Deposit date:2019-07-22
Release date:2020-07-22
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Stapled Peptide Ligand Bound to the Focal Adhesion Targeting (FAT) Domain of the Focal Adhesion Kinase (FAK)
To Be Published
6BZ3
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BU of 6bz3 by Molmil
Complex structure of FAK FAT domain and DCC P3 motif
Descriptor: CALCIUM ION, Focal adhesion kinase 1, Netrin receptor DCC
Authors:Xu, S, Wang, J.-H.
Deposit date:2017-12-22
Release date:2018-04-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.497 Å)
Cite:The binding of DCC-P3 motif and FAK-FAT domain mediates the initial step of netrin-1/DCC signaling for axon attraction.
Cell Discov, 4, 2018
2L6F
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BU of 2l6f by Molmil
NMR Solution structure of FAT domain of FAK complexed with LD2 and LD4 motifs of PAXILLIN
Descriptor: Focal adhesion kinase 1, linker1, Paxillin, ...
Authors:Bertolucci, C.M, Guibao, C, Zhang, C, Zheng, J.
Deposit date:2010-11-19
Release date:2012-05-30
Last modified:2014-04-09
Method:SOLUTION NMR
Cite:NMR Solution Structure of Fat Domain of Fak Complexed with Ld2 and Ld4 Motifs of Paxillin
To be Published
2LK4
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BU of 2lk4 by Molmil
Structural and mechanistic insights into the interaction between PAT Pyk2 and Paxillin LD motif
Descriptor: Protein-tyrosine kinase 2-beta
Authors:Vanarotti, M, Miller, D, Guibao, C, Zheng, J.
Deposit date:2011-10-04
Release date:2012-10-10
Last modified:2014-12-31
Method:SOLUTION NMR
Cite:Structural and Mechanistic Insights into the Interaction between Pyk2 and Paxillin LD Motifs.
J.Mol.Biol., 426, 2014
3S9O
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BU of 3s9o by Molmil
The Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase showing N-terminal interactions in cis
Descriptor: CHLORIDE ION, Focal adhesion kinase 1, SODIUM ION
Authors:Arold, S.T.
Deposit date:2011-06-01
Release date:2012-06-06
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Conformational dynamics of the focal adhesion targeting domain control specific functions of focal adhesion kinase in cells.
J.Biol.Chem., 290, 2015
3U3F
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BU of 3u3f by Molmil
Structural basis for the interaction of Pyk2 PAT domain with paxillin LD motifs
Descriptor: Paxillin LD2 peptide, Protein-tyrosine kinase 2-beta
Authors:Vanarotti, M, Miller, D.J, Guibao, C.C, Zheng, J.J.
Deposit date:2011-10-05
Release date:2012-10-24
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.101 Å)
Cite:Structural and Mechanistic Insights into the Interaction between Pyk2 and Paxillin LD Motifs.
J.Mol.Biol., 426, 2014
2L6G
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BU of 2l6g by Molmil
FAT-LD2 Double labeled construct with free LD4 peptide
Descriptor: Focal adhesion kinase 1, linker, Paxillin
Authors:Bertolucci, C.M, Guibao, C, Zhang, C, Zheng, J.
Deposit date:2010-11-19
Release date:2012-05-30
Last modified:2014-04-09
Method:SOLUTION NMR
Cite:Fat-Ld2 Double Labeled Construct with Free Ld4 Peptide
To be Published
2L6H
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BU of 2l6h by Molmil
Fat domain of focal adhesion kinase tethered to LD4 motif of paxillin via GGS linker
Descriptor: Focal adhesion kinase 1, linker, Paxillin
Authors:Bertolucci, C.M, Guibao, C, Zhang, C, Zheng, J.
Deposit date:2010-11-19
Release date:2012-05-30
Last modified:2014-04-09
Method:SOLUTION NMR
Cite:Fat Domain of Focal Adhesion Kinase Tethered to Ld4 Motif of Paxillin via GGS Linker
To be Published
4XEK
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BU of 4xek by Molmil
Pyk2-FAT domain in complex with leupaxin LD4 motif
Descriptor: 19-mer peptide containing Leupaxin LD4 motif, Protein-tyrosine kinase 2-beta
Authors:Miller, D.J.
Deposit date:2014-12-24
Release date:2015-12-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.793 Å)
Cite:Structural Basis for the Interaction between Pyk2-FAT Domain and Leupaxin LD Repeats.
Biochemistry, 55, 2016
4XEV
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BU of 4xev by Molmil
Fusion of Pyk2-FAT domain with Leupaxin LD1 motif, complexed with Leupaxin LD4 peptide
Descriptor: 19-mer peptide containing Leupaxin LD4 motif, Fusion protein of Protein-tyrosine kinase 2-beta FAT domain and Leupaxin LD1 motif
Authors:Miller, D.J.
Deposit date:2014-12-24
Release date:2015-12-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.0073 Å)
Cite:Structural Basis for the Interaction between Pyk2-FAT Domain and Leupaxin LD Repeats.
Biochemistry, 55, 2016
4XEF
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BU of 4xef by Molmil
Pyk2-FAT complexed with Leupaxin LD motif LD1
Descriptor: 20-mer peptide containing LD1 motif of leupaxin, Protein-tyrosine kinase 2-beta
Authors:Miller, D.J.
Deposit date:2014-12-23
Release date:2015-12-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for the Interaction between Pyk2-FAT Domain and Leupaxin LD Repeats.
Biochemistry, 55, 2016
3GM1
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BU of 3gm1 by Molmil
Crystal Structure of the Focal Adhesion Targeting (FAT) Domain of Pyk2 in Complex with Paxillin LD4 Motif-Derived Peptides
Descriptor: Paxillin, Protein tyrosine kinase 2 beta
Authors:Lulo, J.E, Yuzawa, S, Schlessinger, J.
Deposit date:2009-03-12
Release date:2009-05-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Crystal structures of free and ligand-bound focal adhesion targeting domain of Pyk2
Biochem.Biophys.Res.Commun., 383, 2009
3GM3
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BU of 3gm3 by Molmil
Crystal Structure of the Focal Adhesion Targeting (FAT) Domain of Pyk2
Descriptor: Protein tyrosine kinase 2 beta
Authors:Lulo, J.E, Yuzawa, S, Schlessinger, J.
Deposit date:2009-03-12
Release date:2009-05-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of free and ligand-bound focal adhesion targeting domain of Pyk2
Biochem.Biophys.Res.Commun., 383, 2009
3GM2
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BU of 3gm2 by Molmil
Crystal Structure of the Focal Adhesion Targeting (FAT) Domain of Pyk2
Descriptor: Protein tyrosine kinase 2 beta
Authors:Lulo, J.E, Yuzawa, S, Schlessinger, J.
Deposit date:2009-03-12
Release date:2009-05-05
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Crystal structures of free and ligand-bound focal adhesion targeting domain of Pyk2
Biochem.Biophys.Res.Commun., 383, 2009
7W8B
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BU of 7w8b by Molmil
Crystal Structure of human Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase
Descriptor: Isoform 5 of Focal adhesion kinase 1
Authors:Momin, A.A, Sandholu, A.S, Arold, S.T.
Deposit date:2021-12-07
Release date:2023-07-05
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.093 Å)
Cite:Crystal Structure of human Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase
To Be Published
7W7Z
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BU of 7w7z by Molmil
Crystal Structure of human Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase
Descriptor: Isoform 5 of Focal adhesion kinase 1
Authors:Momin, A.A, Sandholu, A.S, Arold, S.T.
Deposit date:2021-12-07
Release date:2022-12-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal Structure of human Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase
To Be Published
7W8I
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BU of 7w8i by Molmil
Crystal structure of Zn bound human Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase
Descriptor: Isoform 5 of Focal adhesion kinase 1, ZINC ION
Authors:Momin, A.A, Sandholu, A.S, Arold, S.T.
Deposit date:2021-12-07
Release date:2022-12-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.943 Å)
Cite:Crystal structure of Zn bound human Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase
To Be Published
7W9U
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BU of 7w9u by Molmil
Crystal Structure of Zn bound human Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase
Descriptor: Isoform 5 of Focal adhesion kinase 1, ZINC ION
Authors:Momin, A.A, Sandholu, A.S, Arold, S.T.
Deposit date:2021-12-10
Release date:2022-12-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.163 Å)
Cite:Crystal Structure of Zn bound human Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase
To Be Published
1K04
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BU of 1k04 by Molmil
Crystal Structure of the Focal Adhesion Targeting Domain of Focal Adhesion Kinase
Descriptor: CHLORIDE ION, FOCAL ADHESION KINASE 1
Authors:Arold, S.T, Hoellerer, M.K, Noble, M.E.M.
Deposit date:2001-09-18
Release date:2002-01-30
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The structural basis of localization and signaling by the focal adhesion targeting domain.
Structure, 10, 2002
1K05
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BU of 1k05 by Molmil
Crystal structure of the Focal Adhesion Targeting Domain of Focal Adhesion Kinase
Descriptor: FOCAL ADHESION KINASE 1
Authors:Arold, S.T, Hoellerer, M.K, Noble, M.E.M.
Deposit date:2001-09-18
Release date:2002-01-30
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The structural basis of localization and signaling by the focal adhesion targeting domain.
Structure, 10, 2002
1K40
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BU of 1k40 by Molmil
crystal structure of the FAT domain of focal adhesion kinase
Descriptor: adhesion kinase
Authors:Hayashi, I, Vuori, K, Liddington, R.C.
Deposit date:2001-10-04
Release date:2002-02-06
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The focal adhesion targeting (FAT) region of focal adhesion kinase is a four-helix bundle that binds paxillin
Nat.Struct.Biol., 9, 2002
1KTM
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BU of 1ktm by Molmil
SOLUTION STRUCTURE OF FAT DOMAIN OF FOCAL ADHESION KINASE
Descriptor: FOCAL ADHESION KINASE 1
Authors:Liu, G, Guibao, C, Zheng, J.
Deposit date:2002-01-16
Release date:2003-01-16
Last modified:2022-12-21
Method:SOLUTION NMR
Cite:Structural Insight into the Mechanisms of Targeting and Signaling of Focal Adhesion Kinase
Mol.Cell.Biol., 22, 2002
1OW7
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BU of 1ow7 by Molmil
Paxillin LD4 motif bound to the Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase
Descriptor: Focal adhesion kinase 1, Paxillin
Authors:Hoellerer, M.K, Noble, M.E.M, Labesse, G, Werner, J.M, Arold, S.T.
Deposit date:2003-03-28
Release date:2003-10-21
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular Recognition of Paxillin LD Motifs by the Focal Adhesion Targeting Domain
Structure, 11, 2003
1OW6
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BU of 1ow6 by Molmil
Paxillin LD4 motif bound to the Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase
Descriptor: Focal adhesion kinase 1, Paxillin
Authors:Hoellerer, M.K, Noble, M.E.M, Labesse, G, Campbell, I.D, Werner, J.M, Arold, S.T.
Deposit date:2003-03-28
Release date:2003-10-21
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Molecular Recognition of Paxillin LD motifs by the Focal Adhesion Targeting Domain
Structure, 11, 2003

 

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