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8DCM
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BU of 8dcm by Molmil
Crystal structure of Clostridioides difficile binary toxin proCDTb lacking D4 in complex with BINTOXB/22 Fab
Descriptor: ADP-ribosylating binary toxin binding subunit CdtB, BINTOXB/22 Fab heavy chain, BINTOXB/22 Fab light chain, ...
Authors:Goldsmith, J.A, McLellan, J.S.
Deposit date:2022-06-16
Release date:2023-04-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Binding of Neutralizing Antibodies to Clostridioides difficile Binary Toxin.
J.Bacteriol., 205, 2023
1ACC
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BU of 1acc by Molmil
ANTHRAX PROTECTIVE ANTIGEN
Descriptor: ANTHRAX PROTECTIVE ANTIGEN, CALCIUM ION
Authors:Petosa, C, Liddington, R.C.
Deposit date:1997-02-05
Release date:1998-02-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the anthrax toxin protective antigen.
Nature, 385, 1997
4H2A
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BU of 4h2a by Molmil
Crystal structure of wild type protective antigen to 1.62 A (pH 7.5)
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Protective antigen
Authors:Baker, P.J, Sorrell, F.J.
Deposit date:2012-09-12
Release date:2013-09-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Crystal structure of wild type protective antigen to 1.62 A (pH 7.5)
TO BE PUBLISHED
4NAM
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BU of 4nam by Molmil
1.7A structure of 5-Fluoro Tryptophan Labeled Protective Antigen (W206Y)
Descriptor: CALCIUM ION, Protective antigen
Authors:Lovell, S, Battaile, K.P, Chadegani, F, Mulangi, V, Miyagi, M, Bann, J.G.
Deposit date:2013-10-22
Release date:2014-01-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:(19)F nuclear magnetic resonance and crystallographic studies of 5-fluorotryptophan-labeled anthrax protective antigen and effects of the receptor on stability.
Biochemistry, 53, 2014
5FR3
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BU of 5fr3 by Molmil
X-ray crystal structure of aggregation-resistant protective antigen of Bacillus anthracis (mutant S559L T576E)
Descriptor: CALCIUM ION, GLYCEROL, PROTECTIVE ANTIGEN
Authors:Ganesan, A, Siekierska, A, Beerten, J, Brams, M, van Durme, J, De Baets, G, van der Kant, R, Gallardo, R, Ramakers, M, Langenberg, T, Wilkinson, H, De Smet, F, Ulens, C, Rousseau, F, Schymkowitz, J.
Deposit date:2015-12-15
Release date:2016-01-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.935 Å)
Cite:Structural Hot Spots for the Solubility of Globular Proteins
Nat.Commun., 7, 2016
2J42
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BU of 2j42 by Molmil
low quality crystal structure of the transport component C2-II of the C2-toxin from Clostridium botulinum
Descriptor: C2 TOXIN COMPONENT-II
Authors:Schleberger, C, Hochmann, H, Barth, H, Aktories, K, Schulz, G.E.
Deposit date:2006-08-24
Release date:2006-10-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.13 Å)
Cite:Structure and Action of the Binary C2 Toxin from Clostridium Botulinum.
J.Mol.Biol., 364, 2006
7KXR
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BU of 7kxr by Molmil
Protective antigen pore translocating lethal factor N-terminal domain
Descriptor: CALCIUM ION, Lethal factor, Protective antigen
Authors:Machen, A.J, Freudenthal, B.D.
Deposit date:2020-12-04
Release date:2021-07-14
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Anthrax toxin translocation complex reveals insight into the lethal factor unfolding and refolding mechanism.
Sci Rep, 11, 2021
4EE2
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BU of 4ee2 by Molmil
Crystal Structure of Anthrax Protective Antigen K446M Mutant to 1.91-A Resolution
Descriptor: CALCIUM ION, Protective antigen
Authors:Kintzer, A.F, Krantz, B.A.
Deposit date:2012-03-28
Release date:2012-10-24
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Anthrax toxin protective antigen integrates poly-gamma-D-glutamate and pH signals to sense the optimal environment for channel formation.
Proc.Natl.Acad.Sci.USA, 109, 2012
7MJR
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BU of 7mjr by Molmil
Vip4Da2 toxin structure
Descriptor: CALCIUM ION, SULFATE ION, Vip4Da1 protein
Authors:Rydel, T.J, Duda, D, Zheng, M, Henry, A.
Deposit date:2021-04-20
Release date:2021-05-05
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.22 Å)
Cite:Structural and functional insights into the first Bacillus thuringiensis vegetative insecticidal protein of the Vpb4 fold, active against western corn rootworm.
Plos One, 16, 2021
7O85
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BU of 7o85 by Molmil
Anthrax toxin prepore in complex with the neutralizing Fab cAb29
Descriptor: CALCIUM ION, Fab, Protective antigen PA-63
Authors:Hoelzgen, F, Zalk, R, Alcalay, R, Cohen-Schwartz, S, Garau, G, Shahar, A, Mazor, O, Frank, G.A.
Deposit date:2021-04-14
Release date:2021-04-28
Last modified:2021-09-29
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Neutralization of the anthrax toxin by antibody-mediated stapling of its membrane-penetrating loop.
Acta Crystallogr D Struct Biol, 77, 2021
6ZXK
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BU of 6zxk by Molmil
Fully-loaded anthrax lethal toxin in its heptameric pre-pore state and PA7LF(2+1B) arrangement
Descriptor: Lethal factor, Protective antigen
Authors:Quentin, D, Antoni, C, Gatsogiannis, C, Raunser, S.
Deposit date:2020-07-29
Release date:2020-09-02
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structure of the fully-loaded asymmetric anthrax lethal toxin in its heptameric pre-pore state.
Plos Pathog., 16, 2020
6ZXL
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BU of 6zxl by Molmil
Fully-loaded anthrax lethal toxin in its heptameric pre-pore state and PA7LF(2+1A) arrangement
Descriptor: Lethal factor, Protective antigen
Authors:Quentin, D, Antoni, C, Gatsogiannis, C, Raunser, S.
Deposit date:2020-07-29
Release date:2020-09-02
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Cryo-EM structure of the fully-loaded asymmetric anthrax lethal toxin in its heptameric pre-pore state.
Plos Pathog., 16, 2020
6ZXJ
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BU of 6zxj by Molmil
Fully-loaded anthrax lethal toxin in its heptameric pre-pore state, in which the third lethal factor is masked out (PA7LF3-masked)
Descriptor: Lethal factor, Protective antigen
Authors:Quentin, D, Antoni, C, Gatsogiannis, C, Raunser, S.
Deposit date:2020-07-29
Release date:2020-09-02
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structure of the fully-loaded asymmetric anthrax lethal toxin in its heptameric pre-pore state.
Plos Pathog., 16, 2020
6KLW
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BU of 6klw by Molmil
Complex structure of Iota toxin enzymatic component (Ia) and binding component (Ib) pore with long stem
Descriptor: CALCIUM ION, Iota toxin component Ia, Iota toxin component Ib
Authors:Yoshida, T, Yamada, T, Kawamoto, A, Mitsuoka, K, Iwasaki, K, Tsuge, H.
Deposit date:2019-07-30
Release date:2020-01-15
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Cryo-EM structures reveal translocational unfolding in the clostridial binary iota toxin complex.
Nat.Struct.Mol.Biol., 27, 2020
6KLX
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BU of 6klx by Molmil
Pore structure of Iota toxin binding component (Ib)
Descriptor: CALCIUM ION, Iota toxin component Ib
Authors:Yoshida, T, Yamada, T, Kawamoto, A, Mitsuoka, K, Iwasaki, K, Tsuge, H.
Deposit date:2019-07-30
Release date:2020-01-15
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Cryo-EM structures reveal translocational unfolding in the clostridial binary iota toxin complex.
Nat.Struct.Mol.Biol., 27, 2020
6KLO
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BU of 6klo by Molmil
Complex structure of Iota toxin enzymatic component (Ia) and binding component (Ib) pore with short stem
Descriptor: CALCIUM ION, Iota toxin component Ia, Iota toxin component Ib
Authors:Yoshida, T, Yamada, T, Kawamoto, A, Mitsuoka, K, Iwasaki, K, Tsuge, H.
Deposit date:2019-07-30
Release date:2020-01-15
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Cryo-EM structures reveal translocational unfolding in the clostridial binary iota toxin complex.
Nat.Struct.Mol.Biol., 27, 2020
1TZO
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BU of 1tzo by Molmil
Crystal Structure of the Anthrax Toxin Protective Antigen Heptameric Prepore
Descriptor: CALCIUM ION, Protective antigen
Authors:Lacy, D.B, Wigelsworth, D.J, Melnyk, R.A, Collier, R.J.
Deposit date:2004-07-10
Release date:2004-08-17
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structure of heptameric protective antigen bound to an anthrax toxin receptor: A role for receptor in pH-dependent pore formation
Proc.Natl.Acad.Sci.USA, 101, 2004
3TEX
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BU of 3tex by Molmil
Crystal Structure of Anthrax Protective Antigen (Membrane Insertion Loop Deleted) to 1.7-A resolution
Descriptor: CALCIUM ION, Protective antigen
Authors:Feld, G.K, Krantz, B.A.
Deposit date:2011-08-15
Release date:2011-10-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Domain flexibility modulates the heterogeneous assembly mechanism of anthrax toxin protective antigen.
J.Mol.Biol., 415, 2012
3TEW
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BU of 3tew by Molmil
Crystal Structure of Anthrax Protective Antigen (Membrane Insertion Loop Deleted) to 1.45-A resolution
Descriptor: 2-METHOXYETHANOL, CALCIUM ION, Protective antigen
Authors:Feld, G.K, Krantz, B.A.
Deposit date:2011-08-15
Release date:2011-10-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Domain flexibility modulates the heterogeneous assembly mechanism of anthrax toxin protective antigen.
J.Mol.Biol., 415, 2012
3TEZ
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BU of 3tez by Molmil
Crystal Structure of Anthrax Protective Antigen Mutant S337C N664C and dithiolacetone modified to 1.8-A resolution
Descriptor: 2-METHOXYETHANOL, ACETONE, CALCIUM ION, ...
Authors:Feld, G.K, Krantz, B.A.
Deposit date:2011-08-15
Release date:2011-10-26
Last modified:2012-05-23
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Domain flexibility modulates the heterogeneous assembly mechanism of anthrax toxin protective antigen.
J.Mol.Biol., 415, 2012
3TEY
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BU of 3tey by Molmil
Crystal Structure of Anthrax Protective Antigen (Membrane Insertion Loop Deleted) Mutant S337C N664C to 2.06-A resolution
Descriptor: CALCIUM ION, Protective antigen
Authors:Feld, G.K, Krantz, B.A.
Deposit date:2011-08-15
Release date:2011-10-26
Last modified:2012-05-23
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Domain flexibility modulates the heterogeneous assembly mechanism of anthrax toxin protective antigen.
J.Mol.Biol., 415, 2012
7VNJ
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BU of 7vnj by Molmil
Complex structure of Clostridioides difficile enzymatic component (CDTa) and binding component (CDTb) pore with short stem
Descriptor: ADP-ribosylating binary toxin binding subunit CdtB, ADP-ribosyltransferase enzymatic component, CALCIUM ION
Authors:Yamada, T, Kawamoto, A, Yoshida, T, Sato, Y, Kato, T, Tsuge, H.
Deposit date:2021-10-11
Release date:2022-10-26
Method:ELECTRON MICROSCOPY (2.56 Å)
Cite:Cryo-EM structures of the translocational binary toxin complex CDTa-bound CDTb-pore from Clostridioides difficile.
Nat Commun, 13, 2022
7VNN
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BU of 7vnn by Molmil
Complex structure of Clostridioides difficile enzymatic component (CDTa) and binding component (CDTb) pore with long stem
Descriptor: ADP-ribosylating binary toxin binding subunit CdtB, CALCIUM ION, CdtA
Authors:Yamada, T, Kawamoto, A, Yoshida, T, Sato, Y, Kato, T, Tsuge, H.
Deposit date:2021-10-11
Release date:2022-10-26
Last modified:2022-11-02
Method:ELECTRON MICROSCOPY (2.64 Å)
Cite:Cryo-EM structures of the translocational binary toxin complex CDTa-bound CDTb-pore from Clostridioides difficile.
Nat Commun, 13, 2022
3HVD
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BU of 3hvd by Molmil
The Protective Antigen Component of Anthrax Toxin Forms Functional Octameric Complexes
Descriptor: CALCIUM ION, Protective antigen
Authors:Kintzer, A.F, Dong, K.C, Berger, J.M, Krantz, B.A.
Deposit date:2009-06-15
Release date:2009-08-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.209 Å)
Cite:The protective antigen component of anthrax toxin forms functional octameric complexes.
J.Mol.Biol., 392, 2009
3J9C
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BU of 3j9c by Molmil
CryoEM single particle reconstruction of anthrax toxin protective antigen pore at 2.9 Angstrom resolution
Descriptor: CALCIUM ION, Protective antigen PA-63
Authors:Jiang, J, Pentelute, B.L, Collier, R.J, Zhou, Z.H.
Deposit date:2014-12-25
Release date:2015-03-11
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Atomic structure of anthrax protective antigen pore elucidates toxin translocation.
Nature, 521, 2015

 

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