PDB: 129 resultsInfo pagesStatus searchChemie searchBIRD

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4MV4	Crystal Structure of Biotin Carboxylase from Haemophilus influenzae in Complex with AMPPCP and Mg2 Descriptor: 1,2-ETHANEDIOL, Biotin carboxylase, CHLORIDE ION, ... Authors: Broussard, T.C, Pakhomova, S, Neau, D.B, Champion, T.S, Bonnot, R.J, Waldrop, G.L. Deposit date: 2013-09-23 Release date: 2015-01-14 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.61 Å) Cite: Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase. Biochemistry, 54, 2015
4MV3	Crystal Structure of Biotin Carboxylase from Haemophilus influenzae in Complex with AMPPCP and Bicarbonate Descriptor: 1,2-ETHANEDIOL, BICARBONATE ION, Biotin carboxylase, ... Authors: Broussard, T.C, Pakhomova, S, Neau, D.B, Champion, T.S, Bonnot, R.J, Waldrop, G.L. Deposit date: 2013-09-23 Release date: 2015-01-14 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.69 Å) Cite: Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase. Biochemistry, 54, 2015
5H80	Biotin Carboxylase domain of single-chain bacterial carboxylase Descriptor: 1,2-ETHANEDIOL, Carboxylase Authors: Hagmann, A, Hunkeler, M, Stuttfeld, E, Maier, T. Deposit date: 2015-12-23 Release date: 2016-07-20 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Hybrid Structure of a Dynamic Single-Chain Carboxylase from Deinococcus radiodurans. Structure, 24, 2016
4MV7	Crystal Structure of Biotin Carboxylase form Haemophilus influenzae in Complex with Phosphonoformate Descriptor: 1,2-ETHANEDIOL, Biotin carboxylase, PHOSPHONOFORMIC ACID Authors: Broussard, T.C, Pakhomova, S, Neau, D.B, Champion, T.S, Bonnot, R.J, Waldrop, G.L. Deposit date: 2013-09-23 Release date: 2015-01-14 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.73 Å) Cite: Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase. Biochemistry, 54, 2015
2W70	Crystal structure of Biotin carboxylase from E. coli in complex with the amino-thiazole-pyrimidine fragment Descriptor: 4-(2-amino-1,3-thiazol-4-yl)pyrimidin-2-amine, BIOTIN CARBOXYLASE, CHLORIDE ION Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-12-19 Release date: 2009-05-19 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.77 Å) Cite: Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
4MV6	Crystal Structure of Biotin Carboxylase from Haemophilus influenzae in Complex with Phosphonoacetamide Descriptor: 1,2-ETHANEDIOL, Biotin carboxylase, PHOSPHONOACETAMIDE Authors: Broussard, T.C, Pakhomova, S, Neau, D.B, Champion, T.S, Bonnot, R.J, Waldrop, G.L. Deposit date: 2013-09-23 Release date: 2015-01-14 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.77 Å) Cite: Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase. Biochemistry, 54, 2015
1A9X	CARBAMOYL PHOSPHATE SYNTHETASE: CAUGHT IN THE ACT OF GLUTAMINE HYDROLYSIS Descriptor: ADENOSINE-5'-DIPHOSPHATE, CARBAMOYL PHOSPHATE SYNTHETASE (LARGE CHAIN), CARBAMOYL PHOSPHATE SYNTHETASE (SMALL CHAIN), ... Authors: Thoden, J, Holden, H. Deposit date: 1998-04-14 Release date: 1998-10-21 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Carbamoyl phosphate synthetase: caught in the act of glutamine hydrolysis. Biochemistry, 37, 1998
1W96	Crystal Structure of Biotin Carboxylase Domain of Acetyl-coenzyme A Carboxylase from Saccharomyces cerevisiae in Complex with Soraphen A Descriptor: ACETYL-COENZYME A CARBOXYLASE, SORAPHEN A Authors: Shen, Y, Volrath, S.L, Weatherly, S.C, Elich, T.D, Tong, L. Deposit date: 2004-10-06 Release date: 2005-01-04 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: A Mechanism for the Potent Inhibition of Eukaryotic Acetyl-Coenzyme a Carboxylase by Soraphen A, a Macrocyclic Polyketide Natural Product Mol.Cell, 16, 2004
2W6P	Crystal structure of Biotin carboxylase from E. coli in complex with 5-Methyl-6-phenyl-quinazoline-2,4-diamine Descriptor: 5-methyl-6-phenylquinazoline-2,4-diamine, ACETYL-COA CARBOXYLASE Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-12-18 Release date: 2009-05-19 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
2W6N	Crystal structure of Biotin carboxylase from E. coli in complex with amino-oxazole fragment series Descriptor: 2-AMINO-N,N-BIS(PHENYLMETHYL)-1,3-OXAZOLE-5-CARBOXAMIDE, BIOTIN CARBOXYLASE, CHLORIDE ION Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-12-18 Release date: 2009-05-19 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.87 Å) Cite: Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
6UEL	CPS1 bound to allosteric inhibitor H3B-193 Descriptor: Carbamoyl-phosphate synthase [ammonia], mitochondrial, N~1~-[(4-fluorophenyl)methyl]-N~1~-methyl-N~4~-(4-methyl-1,3-thiazol-2-yl)piperidine-1,4-dicarboxamide, ... Authors: Larsen, N.A, Nguyen, T.V. Deposit date: 2019-09-21 Release date: 2020-03-18 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Small Molecule Inhibition of CPS1 Activity through an Allosteric Pocket. Cell Chem Biol, 27, 2020
2W6Z	Crystal structure of Biotin carboxylase from E. coli in complex with the 3-(3-Methyl-but-2-enyl)-3H-purin-6-ylamine fragment Descriptor: 3-(3-methylbut-2-en-1-yl)-3H-purin-6-amine, BIOTIN CARBOXYLASE, CHLORIDE ION Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-12-19 Release date: 2009-05-19 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
1DV1	STRUCTURE OF BIOTIN CARBOXYLASE (APO) Descriptor: BIOTIN CARBOXYLASE, PHOSPHATE ION Authors: Thoden, J.B, Blanchard, C.Z, Holden, H.M, Waldrop, G.L. Deposit date: 2000-01-19 Release date: 2000-06-09 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Movement of the biotin carboxylase B-domain as a result of ATP binding. J.Biol.Chem., 275, 2000
3G8D	Crystal structure of the biotin carboxylase subunit, E296A mutant, of acetyl-COA carboxylase from Escherichia coli Descriptor: ADENOSINE-5'-DIPHOSPHATE, Biotin carboxylase, MAGNESIUM ION, ... Authors: Chou, C.Y, Yu, L.P, Tong, L. Deposit date: 2009-02-12 Release date: 2009-03-03 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure of biotin carboxylase in complex with substrates and implications for its catalytic mechanism. J.Biol.Chem., 284, 2009
3OUZ	Crystal Structure of Biotin Carboxylase-ADP complex from Campylobacter jejuni Descriptor: ADENOSINE-5'-DIPHOSPHATE, Biotin carboxylase, D-MALATE, ... Authors: Maltseva, N, Kim, Y, Makowska-Grzyska, M, Mulligan, R, Papazisi, L, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2010-09-15 Release date: 2010-10-13 Last modified: 2017-11-08 Method: X-RAY DIFFRACTION (1.902 Å) Cite: Crystal Structure of Biotin Carboxylase-ADP complex from Campylobacter jejuni TO BE PUBLISHED
4MV1	Crystal Structure of Biotin Carboxylase from Haemophilus influenzae in Complex with ADP and Phosphate Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Biotin carboxylase, ... Authors: Broussard, T.C, Pakhomova, S, Neau, D.B, Champion, T.S, Bonnot, R.J, Waldrop, G.L. Deposit date: 2013-09-23 Release date: 2015-01-14 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.91 Å) Cite: Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase. Biochemistry, 54, 2015
3RV3	Crystal structure of E.coli biotin carboxylase in complex with two ADP and one Mg ion Descriptor: ADENOSINE-5'-DIPHOSPHATE, Biotin carboxylase, MAGNESIUM ION Authors: Chou, C.Y, Tong, L. Deposit date: 2011-05-05 Release date: 2011-05-18 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.91 Å) Cite: Structural and biochemical studies on the regulation of biotin carboxylase by substrate inhibition and dimerization. J.Biol.Chem., 286, 2011
5MLK	Biotin dependent carboxylase AccA3 dimer from Mycobacterium tuberculosis (Rv3285) Descriptor: Acetyl-COA carboxylase Authors: Bennett, M.D, Hogbom, M. Deposit date: 2016-12-07 Release date: 2017-03-08 Last modified: 2017-05-17 Method: X-RAY DIFFRACTION (1.939 Å) Cite: Crystal structure of the essential biotin-dependent carboxylase AccA3 from Mycobacterium tuberculosis. FEBS Open Bio, 7, 2017
6YBQ	Engineered glycolyl-CoA carboxylase (quintuple mutant) with bound CoA Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, Propionyl-CoA carboxylase alpha subunit, ... Authors: Schuller, J.M, Schuller, S.K, Zarzycki, J, Scheffen, M, Marchal, D.M, Erb, T.J. Deposit date: 2020-03-17 Release date: 2020-10-28 Last modified: 2021-05-12 Method: ELECTRON MICROSCOPY (1.96 Å) Cite: A new-to-nature carboxylation module to improve natural and synthetic CO2 fixation Nat Catal, 2021
4RZQ	Structural Analysis of Substrate, Reaction Intermediate and Product Binding in Haemophilus influenzae Biotin Carboxylase Descriptor: ADENOSINE-5'-DIPHOSPHATE, Biotin carboxylase, methyl (3aS,4S,6aR)-4-(5-methoxy-5-oxopentyl)-2-oxohexahydro-1H-thieno[3,4-d]imidazole-1-carboxylate Authors: Broussard, T.C, Pakhomova, S, Neau, D.B, Champion, T.S, Bonnot, R, Waldrop, G.L. Deposit date: 2014-12-23 Release date: 2015-06-10 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.98 Å) Cite: Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase. Biochemistry, 54, 2015
4MV9	Crystal Structure of Biotin Carboxylase from Haemophilus influenzae in Complex with Bicarbonate Descriptor: 1,2-ETHANEDIOL, BICARBONATE ION, Biotin carboxylase Authors: Broussard, T.C, Pakhomova, S, Neau, D.B, Champion, T.S, Bonnot, R.J, Waldrop, G.L. Deposit date: 2013-09-23 Release date: 2015-01-14 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.98 Å) Cite: Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase. Biochemistry, 54, 2015
3RV4	Crystal structure of E.coli biotin carboxylase R16E mutant in complex with Mg-ADP and bicarbonate Descriptor: ADENOSINE-5'-DIPHOSPHATE, BICARBONATE ION, Biotin carboxylase, ... Authors: Chou, C.Y, Tong, L. Deposit date: 2011-05-05 Release date: 2011-05-18 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.98 Å) Cite: Structural and biochemical studies on the regulation of biotin carboxylase by substrate inhibition and dimerization. J.Biol.Chem., 286, 2011
2W71	Crystal structure of Biotin carboxylase from E. coli in complex with the imidazole-pyrimidine inhibitor Descriptor: 4-[1-(2,6-dichlorobenzyl)-2-methyl-1H-imidazol-4-yl]pyrimidin-2-amine, BIOTIN CARBOXYLASE, CHLORIDE ION Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-12-19 Release date: 2009-05-19 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
3RUP	Crystal structure of E.coli biotin carboxylase in complex with two ADP and two Ca ions Descriptor: ADENOSINE-5'-DIPHOSPHATE, Biotin carboxylase, CALCIUM ION, ... Authors: Chou, C.Y, Tong, L. Deposit date: 2011-05-05 Release date: 2011-05-18 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Structural and biochemical studies on the regulation of biotin carboxylase by substrate inhibition and dimerization. J.Biol.Chem., 286, 2011
1CS0	Crystal structure of carbamoyl phosphate synthetase complexed at CYS269 in the small subunit with the tetrahedral mimic l-glutamate gamma-semialdehyde Descriptor: ADENOSINE-5'-DIPHOSPHATE, CARBAMOYL PHOSPHATE SYNTHETASE: LARGE SUBUNIT, CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT, ... Authors: Thoden, J.B, Huang, X, Raushel, F.M, Holden, H.M. Deposit date: 1999-08-16 Release date: 1999-12-10 Last modified: 2019-11-20 Method: X-RAY DIFFRACTION (2 Å) Cite: The small subunit of carbamoyl phosphate synthetase: snapshots along the reaction pathway. Biochemistry, 38, 1999

 

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