4WL2
 
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3HBC
 | | Crystal Structure of Choloylglycine Hydrolase from Bacteroides thetaiotaomicron VPI | | Descriptor: | 1,2-ETHANEDIOL, Choloylglycine hydrolase, GLYCEROL | | Authors: | Kim, Y, Bigelow, L, Buck, K, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2009-05-04 | | Release date: | 2009-06-02 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.269 Å) | | Cite: | Crystal Structure of Choloylglycine Hydrolase from Bacteroides thetaiotaomicron VPI
To be Published
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2Z71
 | | Structure of truncated mutant CYS1GLY of penicillin V acylase from bacillus sphaericus co-crystallized with penicillin V | | Descriptor: | (2S,5R,6R)-3,3-DIMETHYL-7-OXO-6-(2-PHENOXYACETAMIDO)-4-THIA-1- AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC ACID, Penicillin acylase | | Authors: | Pathak, M.C, Brannigan, J, Dodson, G.G, Suresh, C.G. | | Deposit date: | 2007-08-10 | | Release date: | 2008-08-26 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Studies on the catalysis and post translational processing of penicillin V acylase
To be published
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6UFY
 | | B. theta Bile Salt Hydrolase | | Descriptor: | Choloylglycine hydrolase | | Authors: | Seegar, T.C.M. | | Deposit date: | 2019-09-25 | | Release date: | 2020-02-19 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.71 Å) | | Cite: | Development of a covalent inhibitor of gut bacterial bile salt hydrolases.
Nat.Chem.Biol., 16, 2020
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5X9I
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6UH4
 | | B. theta Bile Salt Hydrolase with covalent inhibitor | | Descriptor: | (5R,6R)-6-[(1S,2R,4aS,4bS,7R,8aS,10R,10aS)-7,10-dihydroxy-1,2,4b-trimethyltetradecahydrophenanthren-2-yl]-5-methylheptan-2-one, Choloylglycine hydrolase | | Authors: | Seegar, T.C.M. | | Deposit date: | 2019-09-26 | | Release date: | 2020-02-19 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.51 Å) | | Cite: | Development of a covalent inhibitor of gut bacterial bile salt hydrolases.
Nat.Chem.Biol., 16, 2020
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8BLT
 | | Structure of Lactobacillus salivarius (Ls) bile salt hydrolase(BSH) in complex with taurocholate (TCA) | | Descriptor: | Bile salt hydrolase, TAUROCHOLIC ACID | | Authors: | Karlov, D.S, Long, S.L, Zeng, X, Xu, F, Lal, K, Cao, L, Hayoun, K, Lin, J, Joyce, S.A, Tikhonova, I.G. | | Deposit date: | 2022-11-10 | | Release date: | 2023-03-08 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Characterization of the mechanism of bile salt hydrolase substrate specificity by experimental and computational analyses.
Structure, 31, 2023
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8BLS
 | | Structure of Lactobacillus salivarius (Ls) bile salt hydrolase(BSH) in complex with Glycocholate (GCA) | | Descriptor: | Bile salt hydrolase, GLYCOCHOLIC ACID | | Authors: | Karlov, D.S, Long, S.L, Zeng, X, Xu, F, Lal, K, Cao, L, Hayoun, K, Lin, J, Joyce, S.A, Tikhonova, I.G. | | Deposit date: | 2022-11-10 | | Release date: | 2023-03-08 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Characterization of the mechanism of bile salt hydrolase substrate specificity by experimental and computational analyses.
Structure, 31, 2023
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5Y7P
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3MJI
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2BJG
 | | Crystal Structure of Conjugated Bile Acid Hydrolase from Clostridium perfringens in Complex with Reaction Products Taurine and Deoxycholate | | Descriptor: | 1,2-ETHANEDIOL, CHOLOYLGLYCINE HYDROLASE | | Authors: | Rossocha, M, Schultz-Heienbrok, R, Von Moeller, H, Coleman, J.P, Saenger, W. | | Deposit date: | 2005-02-02 | | Release date: | 2005-05-03 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Conjugated Bile Acid Hydrolase is a Tetrameric N-Terminal Thiol Hydrolase with Specific Recognition of its Cholyl But not of its Tauryl Product
Biochemistry, 44, 2005
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2BJF
 | | Crystal Structure of Conjugated Bile Acid Hydrolase from Clostridium perfringens in Complex with Reaction Products Taurine and Deoxycholate | | Descriptor: | (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, 2-AMINOETHANESULFONIC ACID, CHOLOYLGLYCINE HYDROLASE, ... | | Authors: | Rossocha, M, Schultz-Heienbrok, R, Von Moeller, H, Coleman, J.P, Saenger, W. | | Deposit date: | 2005-02-02 | | Release date: | 2005-03-03 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.67 Å) | | Cite: | Conjugated Bile Acid Hydrolase is a Tetrameric N-Terminal Thiol Hydrolase with Specific Recognition of its Cholyl But not of its Tauryl Product
Biochemistry, 44, 2005
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3PVA
 | | PENICILLIN V ACYLASE FROM B. SPHAERICUS | | Descriptor: | PROTEIN (PENICILLIN V ACYLASE) | | Authors: | Suresh, C.G, Pundle, A.V, Rao, K.N, Sivaraman, H, Brannigan, J.A, Mcvey, C.E, Verma, C.S, Dauter, Z, Dodson, E.J, Dodson, G.G. | | Deposit date: | 1998-11-13 | | Release date: | 1999-11-15 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Penicillin V acylase crystal structure reveals new Ntn-hydrolase family members.
Nat.Struct.Biol., 6, 1999
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5GS7
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5HKE
 | | bile salt hydrolase from Lactobacillus salivarius | | Descriptor: | Bile salt hydrolase, PHOSPHATE ION | | Authors: | Hu, X.-J. | | Deposit date: | 2016-01-14 | | Release date: | 2016-05-11 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of bile salt hydrolase from Lactobacillus salivarius.
Acta Crystallogr F Struct Biol Commun, 72, 2016
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2HF0
 | | Bifidobacterium longum bile salt hydrolase | | Descriptor: | Bile salt hydrolase | | Authors: | Suresh, C.G, Kumar, R.S, Brannigan, J.A. | | Deposit date: | 2006-06-22 | | Release date: | 2006-09-19 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural and Functional Analysis of a Conjugated Bile Salt Hydrolase from Bifidobacterium longum Reveals an Evolutionary Relationship with Penicillin V Acylase.
J.Biol.Chem., 281, 2006
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2HEZ
 | | Bifidobacterium longum bile salt hydrolase | | Descriptor: | Bile salt hydrolase, SULFATE ION | | Authors: | Suresh, C.G, Kumar, R.S, Brannigan, J.A. | | Deposit date: | 2006-06-22 | | Release date: | 2006-09-19 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural and Functional Analysis of a Conjugated Bile Salt Hydrolase from Bifidobacterium longum Reveals an Evolutionary Relationship with Penicillin V Acylase.
J.Biol.Chem., 281, 2006
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5J9R
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2IWM
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5X8Z
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7SVG
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7SVH
 | | Bile Salt Hydrolase B from Lactobacillus gasseri | | Descriptor: | Choloylglycine hydrolase, MAGNESIUM ION | | Authors: | Walker, M.E, Redinbo, M.R. | | Deposit date: | 2021-11-19 | | Release date: | 2023-01-25 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.56 Å) | | Cite: | Bile salt hydrolases shape the bile acid landscape and restrict Clostridioides difficile growth in the murine gut.
Nat Microbiol, 8, 2023
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7SVF
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7SVK
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7SVE
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