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5MC7
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BU of 5mc7 by Molmil
Crystal structure of Truncated Human Coatomer Protein Complex, subunit Z1 (CopZ1)
Descriptor: Coatomer subunit zeta-1
Authors:Lunev, S, Groves, M.R.
Deposit date:2016-11-09
Release date:2016-12-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of truncated human coatomer protein complex subunit zeta 1 (Cop zeta 1).
Acta Crystallogr F Struct Biol Commun, 73, 2017
2HF6
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BU of 2hf6 by Molmil
Solution structure of human zeta-COP
Descriptor: Coatomer subunit zeta-1
Authors:Yu, W, Jin, C, Xia, B.
Deposit date:2006-06-23
Release date:2007-06-12
Last modified:2011-11-30
Method:SOLUTION NMR
Cite:Solution structure of human zeta-COP: direct evidences for structural similarity between COP I and clathrin-adaptor coats
J.Mol.Biol., 386, 2009
5MU7
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BU of 5mu7 by Molmil
Crystal Structure of the beta/delta-COPI Core Complex
Descriptor: Coatomer subunit beta, Coatomer subunit delta-like protein
Authors:Kopp, J, Aderhold, P, Wieland, F, Sinning, I.
Deposit date:2017-01-12
Release date:2017-06-28
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
4UQI
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BU of 4uqi by Molmil
AP2 controls clathrin polymerization with a membrane-activated switch
Descriptor: AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2 COMPLEX SUBUNIT BETA, AP-2 COMPLEX SUBUNIT MU, ...
Authors:Kelly, B.T, Graham, S.C, Liska, N, Dannhauser, P.N, Hoening, S, Ungewickell, E.J, Owen, D.J.
Deposit date:2014-06-23
Release date:2014-07-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Clathrin Adaptors. Ap2 Controls Clathrin Polymerization with a Membrane-Activated Switch.
Science, 345, 2014
8T1O
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BU of 8t1o by Molmil
AP2 bound to MSP2N2 nanodisc with Tgn38 cargo peptide; composite map
Descriptor: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
Authors:Baker, R.W, Cannon, K.S, Reta, S.
Deposit date:2023-06-02
Release date:2023-07-12
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Lipid nanodiscs as a template for high-resolution cryo-EM structures of peripheral membrane proteins.
J.Struct.Biol., 215, 2023
3TJZ
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BU of 3tjz by Molmil
Crystal Structure of Arf1 Bound to the gamma/zeta-COP Core Complex
Descriptor: ADP-ribosylation factor 1, Coatomer subunit gamma, Coatomer subunit zeta-1, ...
Authors:Goldberg, J, Yu, X, Breitman, M.
Deposit date:2011-08-25
Release date:2012-02-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A structure-based mechanism for arf1-dependent recruitment of coatomer to membranes.
Cell(Cambridge,Mass.), 148, 2012
6URI
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BU of 6uri by Molmil
HIV-1 Nef in complex with the CD4 cytoplasmic domain and the AP2 clathrin adaptor complex
Descriptor: AP-2 complex subunit alpha, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
Authors:Jia, X, Kwon, Y.
Deposit date:2019-10-23
Release date:2020-07-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis of CD4 downregulation by HIV-1 Nef.
Nat.Struct.Mol.Biol., 27, 2020
4HMY
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BU of 4hmy by Molmil
Structural basis for recruitment and activation of the AP-1 clathrin adaptor complex by Arf1
Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Ren, X, Farias, G.G, Canagarajah, B.J, Bonifacino, J.S, Hurley, J.H.
Deposit date:2012-10-18
Release date:2013-03-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (7 Å)
Cite:Structural Basis for Recruitment and Activation of the AP-1 Clathrin Adaptor Complex by Arf1.
Cell(Cambridge,Mass.), 152, 2013
2BP5
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BU of 2bp5 by Molmil
MU2 ADAPTIN SUBUNIT (AP50) OF AP2 ADAPTOR (SECOND DOMAIN), COMPLEXED WITH NON-CANONICAL INTERNALIZATION PEPTIDE VEDYEQGLSG
Descriptor: CLATHRIN COAT ASSEMBLY PROTEIN AP50, P2X PURINOCEPTOR 4
Authors:Royle, S.J, Evans, P.R, Owen, D.J, Murrell-Lagnado, R.D.
Deposit date:2005-04-18
Release date:2005-07-06
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Non-Canonical Yxxg-Phi Endocytic Motifs: Recognition by Ap2 and Preferential Utilization in P2X4 Receptors.
J.Cell.Sci, 118, 2005
1W63
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BU of 1w63 by Molmil
AP1 clathrin adaptor core
Descriptor: ADAPTER-RELATED PROTEIN COMPLEX 1 BETA 1 SUBUNIT, ADAPTER-RELATED PROTEIN COMPLEX 1 GAMMA 1 SUBUNIT, ADAPTER-RELATED PROTEIN COMPLEX 1 SIGMA 1A SUBUNIT, ...
Authors:Heldwein, E, Macia, E, Wang, J, Yin, H.L, Kirchhausen, T, Harrison, S.C.
Deposit date:2004-08-12
Release date:2004-09-21
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (4 Å)
Cite:Crystal Structure of the Clathrin Adaptor Protein 1 Core
Proc.Natl.Acad.Sci.USA, 101, 2004
5FPI
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BU of 5fpi by Molmil
Mu2 adaptin subunit of the AP2 adaptor (C-terminal domain) complexed with Integrin alpha4 internalisation peptide QYKSILQE
Descriptor: AP-2 COMPLEX SUBUNIT MU, INTEGRIN ALPHA-4 SUBUNIT
Authors:Owen, D.J, Evans, P.R, Ivaska, J.
Deposit date:2015-11-30
Release date:2016-01-20
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Selective Integrin Endocytosis is Driven by Alpha Chain:Ap2 Interactions
Nat.Struct.Mol.Biol., 23, 2016
2VGL
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BU of 2vgl by Molmil
AP2 CLATHRIN ADAPTOR CORE
Descriptor: ADAPTOR PROTEIN COMPLEX AP-2, ALPHA 2 SUBUNIT, AP-2 COMPLEX SUBUNIT BETA-1, ...
Authors:Owen, D.J, Collins, B.M, McCoy, A.J, Evans, P.R.
Deposit date:2007-11-14
Release date:2007-12-25
Last modified:2020-10-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular Architecture and Functional Model of the Endocytic Ap2 Complex
Cell(Cambridge,Mass.), 109, 2002
7UX3
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BU of 7ux3 by Molmil
Asymmetric unit of AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated narrow membrane tubes
Descriptor: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Hooy, R.M, Hurley, J.H.
Deposit date:2022-05-04
Release date:2023-05-10
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (9.6 Å)
Cite:Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022
2XA7
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BU of 2xa7 by Molmil
AP2 clathrin adaptor core in active complex with cargo peptides
Descriptor: ADAPTOR-RELATED PROTEIN COMPLEX 2, ALPHA 2 SUBUNIT, AP-2 COMPLEX SUBUNIT BETA, ...
Authors:Jackson, L.P, Kelly, B.T, McCoy, A.J, Evans, P.R, Owen, D.J.
Deposit date:2010-03-29
Release date:2010-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A Large Scale Conformational Change Couples Membrane Recruitment to Cargo Binding in the Ap2 Clathrin Adaptor Complex
Cell(Cambridge,Mass.), 141, 2010
4NEE
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BU of 4nee by Molmil
crystal structure of AP-2 alpha/simga2 complex bound to HIV-1 Nef
Descriptor: AP-2 complex subunit alpha-2, AP-2 complex subunit sigma, Protein Nef
Authors:Hurley, J.H, Bonifacino, J.S, Ren, X, Park, S.Y.
Deposit date:2013-10-29
Release date:2014-01-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8841 Å)
Cite:How HIV-1 Nef hijacks the AP-2 clathrin adaptor to downregulate CD4.
Elife, 3, 2014
7Z5C
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BU of 7z5c by Molmil
Chimera of AP2 with FCHO2 linker domain as a fusion on Cmu2 subunit
Descriptor: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
Authors:Kane Dickson, V, Qu, K, Owen, D.J, Briggs, J.A, Zaccai, N.R.
Deposit date:2022-03-09
Release date:2022-05-11
Method:ELECTRON MICROSCOPY (4.16 Å)
Cite:FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
4P6Z
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BU of 4p6z by Molmil
Crystal structure of the human BST2 cytoplasmic domain and the HIV-1 Vpu cytoplasmic domain bound to the clathrin adaptor protein complex 1 (AP1) core
Descriptor: AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, AP-1 complex subunit mu-1, ...
Authors:Jia, X, Xiong, Y.
Deposit date:2014-03-25
Release date:2014-05-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis of HIV-1 Vpu-mediated BST2 antagonism via hijacking of the clathrin adaptor protein complex 1.
Elife, 3, 2014
6YAF
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BU of 6yaf by Molmil
AP2 on a membrane containing tyrosine-based cargo peptide
Descriptor: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
Authors:Kovtun, O, Kane Dickson, V, Kelly, B.T, Owen, D, Briggs, J.A.G.
Deposit date:2020-03-12
Release date:2020-07-29
Last modified:2020-08-19
Method:ELECTRON MICROSCOPY (9.1 Å)
Cite:Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles.
Sci Adv, 6, 2020
6YAE
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BU of 6yae by Molmil
AP2 core in physiological buffer
Descriptor: AP-2 complex subunit alpha, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
Authors:Kane Dickson, V, Kovtun, O, Kelly, B.T, Owen, D.J, Briggs, J.A.G.
Deposit date:2020-03-12
Release date:2020-07-29
Last modified:2020-08-19
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles.
Sci Adv, 6, 2020
6YAH
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BU of 6yah by Molmil
AP2 in clathrin coats assembled on a membrane containing dileucine- and tyrosine-based cargo peptides
Descriptor: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
Authors:Kovtun, O, Kane Dickson, V, Kelly, B.T, Owen, D, Briggs, J.A.G.
Deposit date:2020-03-12
Release date:2020-07-29
Last modified:2020-08-19
Method:ELECTRON MICROSCOPY (10.2 Å)
Cite:Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles.
Sci Adv, 6, 2020
2JKT
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BU of 2jkt by Molmil
AP2 CLATHRIN ADAPTOR CORE with CD4 Dileucine peptide RM(phosphoS) EIKRLLSE Q to E mutant
Descriptor: AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2 COMPLEX SUBUNIT BETA-1, AP-2 COMPLEX SUBUNIT MU-1, ...
Authors:Owen, D.J, McCoy, A.J, Kelly, B.T, Evans, P.R.
Deposit date:2008-08-29
Release date:2008-10-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:A Structural Explanation for the Binding of Endocytic Dileucine Motifs by the Ap2 Complex.
Nature, 456, 2008
2JKR
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BU of 2jkr by Molmil
AP2 CLATHRIN ADAPTOR CORE with Dileucine peptide RM(phosphoS)QIKRLLSE
Descriptor: AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2 COMPLEX SUBUNIT BETA-1, AP-2 COMPLEX SUBUNIT MU-1, ...
Authors:Owen, D.J, McCoy, A.J, Kelly, B.T, Evans, P.R.
Deposit date:2008-08-29
Release date:2008-10-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:A Structural Explanation for the Binding of Endocytic Dileucine Motifs by the Ap2 Complex.
Nature, 456, 2008
5NZS
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BU of 5nzs by Molmil
The structure of the COPI coat leaf in complex with the ArfGAP2 uncoating factor
Descriptor: ADP-ribosylation factor 1, ADP-ribosylation factor GTPase-activating protein 2, Coatomer subunit alpha, ...
Authors:Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G.
Deposit date:2017-05-15
Release date:2017-06-28
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (10.1 Å)
Cite:9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
5NZR
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BU of 5nzr by Molmil
The structure of the COPI coat leaf
Descriptor: ADP-ribosylation factor 1, Coatomer subunit alpha, Coatomer subunit beta, ...
Authors:Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G.
Deposit date:2017-05-15
Release date:2017-06-28
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (9.2 Å)
Cite:9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017
5NZU
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BU of 5nzu by Molmil
The structure of the COPI coat linkage II
Descriptor: ADP-ribosylation factor 1, Coatomer subunit alpha, Coatomer subunit beta, ...
Authors:Dodonova, S.O, Aderhold, P, Kopp, J, Ganeva, I, Roehling, S, Hagen, W.J.H, Sinning, I, Wieland, F, Briggs, J.A.G.
Deposit date:2017-05-15
Release date:2017-06-28
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (15 Å)
Cite:9 angstrom structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments.
Elife, 6, 2017

 

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