Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

4XWK
DownloadVisualize
BU of 4xwk by Molmil
P-glycoprotein co-crystallized with BDE-100
Descriptor: 2,4-dibromophenyl 2,4,6-tribromophenyl ether, Multidrug resistance protein 1A
Authors:McGrath, A.P, Rees, S.D, Chang, G.
Deposit date:2015-01-28
Release date:2016-04-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Global marine pollutants inhibit P-glycoprotein: Environmental levels, inhibitory effects, and cocrystal structure.
Sci Adv, 2, 2016
2ONJ
DownloadVisualize
BU of 2onj by Molmil
Structure of the multidrug ABC transporter Sav1866 from S. aureus in complex with AMP-PNP
Descriptor: Multidrug export ATP-binding/permease protein SAV1866, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SODIUM ION
Authors:Dawson, R.J.P, Locher, K.P.
Deposit date:2007-01-24
Release date:2007-03-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structure of the multidrug ABC transporter Sav1866 from Staphylococcus aureus in complex with AMP-PNP.
Febs Lett., 581, 2007
2HYD
DownloadVisualize
BU of 2hyd by Molmil
Multidrug ABC transporter SAV1866
Descriptor: ABC transporter homolog, ADENOSINE-5'-DIPHOSPHATE, SODIUM ION
Authors:Dawson, R.J.P, Locher, K.P.
Deposit date:2006-08-05
Release date:2006-09-05
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of a bacterial multidrug ABC transporter.
Nature, 443, 2006
3QF4
DownloadVisualize
BU of 3qf4 by Molmil
Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation
Descriptor: ABC transporter, ATP-binding protein, MAGNESIUM ION, ...
Authors:Hohl, M, Briand, C, Gruetter, M.G, Seeger, M.A.
Deposit date:2011-01-21
Release date:2012-03-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation
Nat.Struct.Mol.Biol., 19, 2012
6VQU
DownloadVisualize
BU of 6vqu by Molmil
Structure of a bacterial Atm1-family ABC exporter
Descriptor: ATM1-type heavy metal exporter
Authors:Fan, C, Rees, D.C.
Deposit date:2020-02-05
Release date:2020-07-29
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.88 Å)
Cite:A structural framework for unidirectional transport by a bacterial ABC exporter.
Proc.Natl.Acad.Sci.USA, 117, 2020
6VQT
DownloadVisualize
BU of 6vqt by Molmil
Structure of a bacterial Atm1-family ABC exporter with MgADPVO4 bound
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATM1-type heavy metal exporter, MAGNESIUM ION, ...
Authors:Fan, C, Rees, D.C.
Deposit date:2020-02-05
Release date:2020-07-29
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:A structural framework for unidirectional transport by a bacterial ABC exporter.
Proc.Natl.Acad.Sci.USA, 117, 2020
3G60
DownloadVisualize
BU of 3g60 by Molmil
Structure of P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
Descriptor: (4R,11R,18R)-4,11,18-tri(propan-2-yl)-6,13,20-triselena-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1~5,8~.1~12,15~]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, Multidrug resistance protein 1a
Authors:Aller, S.G, Yu, J, Ward, A, Weng, Y, Chittaboina, S, Zhuo, R, Harrell, P.M, Trinh, Y.T, Zhang, Q, Urbatsch, I.L, Chang, G.
Deposit date:2009-02-05
Release date:2009-03-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (4.4 Å)
Cite:Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding.
Science, 323, 2009
5OFR
DownloadVisualize
BU of 5ofr by Molmil
Structure of the antibacterial peptide ABC transporter McjD in a high energy outward occluded intermediate state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Microcin-J25 export ATP-binding/permease protein McjD, ...
Authors:Beis, K, Bountra, K.
Deposit date:2017-07-11
Release date:2017-09-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural basis for antibacterial peptide self-immunity by the bacterial ABC transporter McjD.
EMBO J., 36, 2017
3G5U
DownloadVisualize
BU of 3g5u by Molmil
Structure of P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
Descriptor: MERCURY (II) ION, Multidrug resistance protein 1a
Authors:Aller, S.G, Yu, J, Ward, A, Weng, Y, Chittaboina, S, Zhuo, R, Harrell, P.M, Trinh, Y.T, Zhang, Q, Urbatsch, I.L, Chang, G.
Deposit date:2009-02-05
Release date:2009-03-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding.
Science, 323, 2009
5OCH
DownloadVisualize
BU of 5och by Molmil
The crystal structure of human ABCB8 in an outward-facing state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-binding cassette sub-family B member 8, mitochondrial, ...
Authors:Faust, B, Pike, A.C.W, Shintre, C.A, Quiqley, A.M, Chu, A, Barr, A, Shrestha, L, Mukhopadhyay, S, Borkowska, O, Chalk, R, Burgess-Brown, N.A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC)
Deposit date:2017-06-30
Release date:2018-07-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:The crystal structure of human ABCB8 in an outward-facing state
To Be Published
5OFP
DownloadVisualize
BU of 5ofp by Molmil
Structure of the antibacterial peptide ABC transporter McjD in an apo inward occluded conformation
Descriptor: Microcin-J25 export ATP-binding/permease protein McjD
Authors:Beis, K, Choudhury, H.G.
Deposit date:2017-07-11
Release date:2017-09-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (4.71 Å)
Cite:Structural basis for antibacterial peptide self-immunity by the bacterial ABC transporter McjD.
EMBO J., 36, 2017
3G61
DownloadVisualize
BU of 3g61 by Molmil
Structure of P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
Descriptor: (4S,11S,18S)-4,11,18-tri(propan-2-yl)-6,13,20-triselena-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1~5,8~.1~12,15~]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, Multidrug resistance protein 1a
Authors:Aller, S.G, Yu, J, Ward, A, Weng, Y, Chittaboina, S, Zhuo, R, Harrell, P.M, Trinh, Y.T, Zhang, Q, Urbatsch, I.L, Chang, G.
Deposit date:2009-02-05
Release date:2009-03-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (4.35 Å)
Cite:Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding.
Science, 323, 2009
3WMG
DownloadVisualize
BU of 3wmg by Molmil
Crystal structure of an inward-facing eukaryotic ABC multidrug transporter G277V/A278V/A279V mutant in complex with an cyclic peptide inhibitor, aCAP
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ATP-binding cassette, sub-family B, ...
Authors:Kodan, A, Yamaguchi, T, Nakatsu, T, Sakiyama, K, Hipolito, C.J, Fujioka, A, Hirokane, R, Ikeguchi, K, Watanabe, B, Hirtake, J, Kimura, Y, Suga, H, Ueda, K, Kato, H.
Deposit date:2013-11-18
Release date:2014-04-30
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for gating mechanisms of a eukaryotic P-glycoprotein homolog.
Proc.Natl.Acad.Sci.USA, 111, 2014
3WME
DownloadVisualize
BU of 3wme by Molmil
Crystal structure of an inward-facing eukaryotic ABC multidrug transporter
Descriptor: ATP-binding cassette, sub-family B, member 1, ...
Authors:Kodan, A, Yamaguchi, T, Nakatsu, T, Kato, H.
Deposit date:2013-11-18
Release date:2014-03-19
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.751 Å)
Cite:Structural basis for gating mechanisms of a eukaryotic P-glycoprotein homolog.
Proc.Natl.Acad.Sci.USA, 111, 2014
3WMF
DownloadVisualize
BU of 3wmf by Molmil
Crystal structure of an inward-facing eukaryotic ABC multitrug transporter G277V/A278V/A279V mutant
Descriptor: ATP-binding cassette, sub-family B, member 1, ...
Authors:Kodan, A, Yamaguchi, T, Nakatsu, T, Kato, H.
Deposit date:2013-11-18
Release date:2014-03-19
Last modified:2022-08-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for gating mechanisms of a eukaryotic P-glycoprotein homolog.
Proc.Natl.Acad.Sci.USA, 111, 2014
4F4C
DownloadVisualize
BU of 4f4c by Molmil
The Crystal Structure of the Multi-Drug Transporter
Descriptor: Multidrug resistance protein pgp-1, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, undecyl 4-O-alpha-D-glucopyranosyl-1-thio-beta-D-glucopyranoside
Authors:Jin, M.S, Oldham, M.L, Zhang, Q, Chen, J.
Deposit date:2012-05-10
Release date:2012-09-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal structure of the multidrug transporter P-glycoprotein from Caenorhabditis elegans.
Nature, 490, 2012
5C76
DownloadVisualize
BU of 5c76 by Molmil
ATP-driven lipid-linked oligosaccharide flippase PglK in apo-inward facing state (2)
Descriptor: WlaB protein
Authors:Perez, C, Gerber, S, Locher, K.P.
Deposit date:2015-06-24
Release date:2015-08-19
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.94 Å)
Cite:Structure and mechanism of an active lipid-linked oligosaccharide flippase.
Nature, 524, 2015
5C73
DownloadVisualize
BU of 5c73 by Molmil
ATP-driven lipid-linked oligosaccharide flippase PglK in outward-occluded conformation
Descriptor: Protein glycosylation K
Authors:Perez, C, Locher, K.P.
Deposit date:2015-06-24
Release date:2015-08-19
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (5.9 Å)
Cite:Structure and mechanism of an active lipid-linked oligosaccharide flippase.
Nature, 524, 2015
5C78
DownloadVisualize
BU of 5c78 by Molmil
ATP-driven lipid-linked oligosaccharide flippase PglK in apo-inward state (1)
Descriptor: ATP-driven flippase PglK, PENTAETHYLENE GLYCOL
Authors:Perez, C, Locher, K.P.
Deposit date:2015-06-24
Release date:2015-08-19
Last modified:2015-09-02
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure and mechanism of an active lipid-linked oligosaccharide flippase.
Nature, 524, 2015
5EG1
DownloadVisualize
BU of 5eg1 by Molmil
Antibacterial peptide ABC transporter McjD with a resolved lipid
Descriptor: (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, MAGNESIUM ION, Microcin-J25 export ATP-binding/permease protein McjD, ...
Authors:Choudhury, H.G, Beis, K.
Deposit date:2015-10-26
Release date:2016-08-31
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.42 Å)
Cite:Structural and Functional Basis for Lipid Synergy on the Activity of the Antibacterial Peptide ABC Transporter McjD.
J.Biol.Chem., 291, 2016
4KSD
DownloadVisualize
BU of 4ksd by Molmil
Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain
Descriptor: Multidrug resistance protein 1A, R2 protein
Authors:Ward, A, Szewczyk, P, Grimard, V, Lee, C.-W, Martinez, L, Doshi, R, Caya, A, Villaluz, M, Pardon, E, Cregger, C, Swartz, D.J, Falson, P, Urbatsch, I, Govaerts, C, Steyaert, J, Chang, G.
Deposit date:2013-05-17
Release date:2013-07-31
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (4.1001 Å)
Cite:Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KSC
DownloadVisualize
BU of 4ksc by Molmil
Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain
Descriptor: Multidrug resistance protein 1A
Authors:Ward, A, Szewczyk, P, Grimard, V, Lee, C.-W, Martinez, L, Doshi, R, Caya, A, Villaluz, M, Pardon, E, Cregger, C, Swartz, D.J, Falson, P, Urbatsch, I, Govaerts, C, Steyaert, J, Chang, G.
Deposit date:2013-05-17
Release date:2013-07-31
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KSB
DownloadVisualize
BU of 4ksb by Molmil
Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain
Descriptor: Multidrug resistance protein 1A
Authors:Ward, A, Szewczyk, P, Grimard, V, Lee, C.-W, Martinez, L, Doshi, R, Caya, A, Villaluz, M, Pardon, E, Cregger, C, Swartz, D.J, Falson, P, Urbatsch, I, Govaerts, C, Steyaert, J, Chang, G.
Deposit date:2013-05-17
Release date:2013-07-31
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.8001 Å)
Cite:Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain.
Proc.Natl.Acad.Sci.USA, 110, 2013
6C0V
DownloadVisualize
BU of 6c0v by Molmil
Molecular structure of human P-glycoprotein in the ATP-bound, outward-facing conformation
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Multidrug resistance protein 1
Authors:Kim, Y.J, Chen, J.
Deposit date:2018-01-02
Release date:2018-01-31
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular structure of human P-glycoprotein in the ATP-bound, outward-facing conformation.
Science, 359, 2018
6C3P
DownloadVisualize
BU of 6c3p by Molmil
Cryo-EM structure of human KATP bound to ATP and ADP in propeller form
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ...
Authors:Lee, K.P.K, Chen, J, MacKinnon, R.
Deposit date:2018-01-10
Release date:2018-01-24
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:Molecular structure of human KATP in complex with ATP and ADP.
Elife, 6, 2017

217705

건을2024-03-27부터공개중

PDB statisticsPDBj update infoContact PDBjnumon