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5KA6	HIV-1 gp41 variant Q552R and L555M resistance mutations Descriptor: Transmembrane protein gp41 Authors: Bhardwaj, A, Khasnis, M.D, Halkidis, K, Root, M.J. Deposit date: 2016-06-01 Release date: 2016-12-14 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Receptor Activation of HIV-1 Env Leads to Asymmetric Exposure of the gp41 Trimer. PLoS Pathog., 12, 2016
7AEJ	Crystal structure of asymmetric HIV-1 gp41 containing all membrane anchors Descriptor: 2H10, Envelope glycoprotein gp160,Envelope glycoprotein gp160 Authors: Caillat, C, Guilligay, D, Weissenhorn, W. Deposit date: 2020-09-17 Release date: 2021-05-26 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (3.8 Å) Cite: Structure of HIV-1 gp41 with its membrane anchors targeted by neutralizing antibodies. Elife, 10, 2021
3WFV	HIV-1 CRF07 gp41 Descriptor: Envelope glycoprotein gp160 Authors: Du, J, Xue, H, Ma, J, Liu, F, Zhou, J, Shao, Y, Qiao, W, Liu, X. Deposit date: 2013-07-24 Release date: 2013-10-16 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: The crystal structure of HIV CRF07 B'/C gp41 reveals a hyper-mutant site in the middle of HR2 heptad repeat Virology, 446, 2013
1SZT	ATOMIC STRUCTURE OF A THERMOSTABLE SUBDOMAIN OF HIV-1 GP41 Descriptor: HIV-1 ENVELOPE GLYCOPROTEIN GP41 Authors: Tan, K, Lu, M, Wang, J.-H. Deposit date: 1997-07-28 Release date: 1997-12-24 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Atomic structure of a thermostable subdomain of HIV-1 gp41. Proc.Natl.Acad.Sci.USA, 94, 1997
2OT5	Crystal structure of the HIV gp41 core with the enfuvirtide resistance mutation N43D Descriptor: HIV-1 gp41 glycoprotein Authors: Bai, X, Seedorff, J.E, Green, J, Dwyer, J.J. Deposit date: 2007-02-07 Release date: 2008-06-17 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Impact of the enfuvirtide resistance mutation N43D and the associated baseline polymorphism E137K on peptide sensitivity and six-helix bundle structure. Biochemistry, 47, 2008
6R2G	Crystal structure of a single-chain protein mimetic of the gp41 NHR trimer in complex with the synthetic CHR peptide C34 Descriptor: Envelope glycoprotein gp160, PHOSPHATE ION, Single-chain protein mimetics of the N-terminal heptad-repeat region of gp41 Authors: Camara-Artigas, A, Conejero-Lara, F, Jurado, S, Cano-Munoz, M, Morel, B. Deposit date: 2019-03-17 Release date: 2019-07-10 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural and Thermodynamic Analysis of HIV-1 Fusion Inhibition Using Small gp41 Mimetic Proteins. J.Mol.Biol., 431, 2019
4KHT	Triple helix bundle of GP41 complexed with fab 8066 Descriptor: 8066 heavy chain, 8066 light chain, Gp41 helix Authors: Li, M, Gustchina, A, Wlodawer, A. Deposit date: 2013-05-01 Release date: 2014-03-12 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (2.817 Å) Cite: Complexes of neutralizing and non-neutralizing affinity matured Fabs with a mimetic of the internal trimeric coiled-coil of HIV-1 gp41. Plos One, 8, 2013
2SIV	SIV GP41 CORE STRUCTURE Descriptor: SIV GP41 GLYCOPROTEIN Authors: Malashkevich, V.N, Chan, D.C, Chutkowski, C.T, Kim, P.S. Deposit date: 1998-06-17 Release date: 1998-08-19 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structure of the simian immunodeficiency virus (SIV) gp41 core: conserved helical interactions underlie the broad inhibitory activity of gp41 peptides. Proc.Natl.Acad.Sci.USA, 95, 1998
4KHX	Crystal structure of gp41 helix complexed with antibody 8062 Descriptor: 8062 heavy chain, 8062 light chain, gp41 helix Authors: Li, M, Gustchina, A, Wlodawer, A. Deposit date: 2013-05-01 Release date: 2014-03-12 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (2.921 Å) Cite: Complexes of neutralizing and non-neutralizing affinity matured Fabs with a mimetic of the internal trimeric coiled-coil of HIV-1 gp41. Plos One, 8, 2013
6SNE	crystal structure of LN01 Fab in complex with an HIV-1 gp41 peptide Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, LN01 heavy chain, ... Authors: Caillat, C, Pinto, D, Corti, D, Fenwick, C, Pantaleo, G, Weissenhorn, W. Deposit date: 2019-08-23 Release date: 2019-11-06 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (3.9 Å) Cite: Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01. Cell Host Microbe, 26, 2019
3CYO	Structure of a longer thermalstable core domain of HIV-1 GP41 containing the enfuvirtide resistance mutation N43D and complementary mutation E137K Descriptor: Transmembrane protein Authors: Wang, Z.M, Dwyer, J.J. Deposit date: 2008-04-25 Release date: 2008-06-17 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Impact of the enfuvirtide resistance mutation N43D and the associated baseline polymorphism E137K on peptide sensitivity and six-helix bundle structure. Biochemistry, 47, 2008
3CP1	Structure of a longer thermalstable core domain of HIV-1 gp41 containing the enfuvirtide resistance mutation N43D Descriptor: Transmembrane Protein Authors: Wang, Z.M, Dwyer, J.J. Deposit date: 2008-03-30 Release date: 2008-06-17 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2 Å) Cite: Impact of the enfuvirtide resistance mutation N43D and the associated baseline polymorphism E137K on peptide sensitivity and six-helix bundle structure. Biochemistry, 47, 2008
2XRA	crystal structure of the HK20 Fab in complex with a gp41 mimetic 5- Helix Descriptor: HK20, HUMAN MONOCLONAL ANTIBODY HEAVY CHAIN, HUMAN MONOCLONAL ANTIBODY LIGHT CHAIN, ... Authors: Sabin, C, Corti, D, Buzon, V, Seaman, M.S, Lutje Hulsik, D, Hinz, A, Vanzetta, F, Agatic, G, Silacci, C, Langedijk, J.P.M, Mainetti, L, Scarlatti, G, Sallusto, F, Weiss, R, Lanzavecchia, A, Weissenhorn, W. Deposit date: 2010-09-13 Release date: 2010-12-15 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structure and size-dependent neutralization properties of HK20, a human monoclonal antibody binding to the highly conserved heptad repeat 1 of gp41. PLoS Pathog., 6, 2010
1QBZ	THE CRYSTAL STRUCTURE OF THE SIV GP41 ECTODOMAIN AT 1.47 A Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, CHLORIDE ION, MERCURY (II) ION, ... Authors: Yang, Z.-N, Mueser, T.C, Kaufman, J, Stahl, S.J, Wingfield, P.T, Hyde, C.C. Deposit date: 1999-04-28 Release date: 1999-05-17 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (1.47 Å) Cite: The crystal structure of the SIV gp41 ectodomain at 1.47 A resolution. J.Struct.Biol., 126, 1999
1QCE	SOLUTION NMR STRUCTURE OF ECTODOMAIN OF SIV GP41, RESTRAINED REGULARIZED MEAN STRUCTURE PLUS 29 SIMULATED ANNEALING STRUCTURES Descriptor: PROTEIN (GP41) Authors: Clore, G.M. Deposit date: 1999-04-30 Release date: 1999-07-18 Last modified: 2023-12-27 Method: SOLUTION NMR Cite: Measurement of Residual Dipolar Couplings of Macromolecules Aligned in the Nematic Phase of Acolloidal Suspension of Rod-Shaped Viruses J.Am.Chem.Soc., 121, 1999
1K33	Crystal structure analysis of the gp41 core mutant Descriptor: Transmembrane glycoprotein GP41 Authors: Shu, W, Lu, M. Deposit date: 2001-10-01 Release date: 2001-10-10 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Interhelical interactions in the gp41 core: implications for activation of HIV-1 membrane fusion. Biochemistry, 41, 2002
1K34	Crystal structure analysis of gp41 core mutant Descriptor: Transmembrane glycoprotein GP41 Authors: Shu, W, Lu, M. Deposit date: 2001-10-01 Release date: 2001-10-10 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.88 Å) Cite: Interhelical interactions in the gp41 core: implications for activation of HIV-1 membrane fusion. Biochemistry, 41, 2002
1JQ0	Mutation that destabilize the gp41 core: determinants for stabilizing the SIV/CPmac envelope glycoprotein complex. Mutant structure. Descriptor: gp41 envelope protein Authors: Liu, J, Wang, S, LaBranche, C.C, Hoxie, J.A, Lu, M. Deposit date: 2001-08-03 Release date: 2002-04-24 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Mutations that destabilize the gp41 core are determinants for stabilizing the simian immunodeficiency virus-CPmac envelope glycoprotein complex. J.Biol.Chem., 277, 2002
1JPX	Mutation that destabilize the gp41 core: determinants for stabilizing the SIV/CPmac envelope glycoprotein complex. Wild type. Descriptor: gp41 envelope protein Authors: Liu, J, Wang, S, LaBranche, C.C, Hoxie, J.A, Lu, M. Deposit date: 2001-08-03 Release date: 2002-04-24 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Mutations that destabilize the gp41 core are determinants for stabilizing the simian immunodeficiency virus-CPmac envelope glycoprotein complex. J.Biol.Chem., 277, 2002
2EZP	SOLUTION NMR STRUCTURE OF ECTODOMAIN OF SIV GP41, MODELS 1-10 OF AN ENSEMBLE OF 40 SIMULATED ANNEALING STRUCTURES Descriptor: GP41 Authors: Caffrey, M, Gronenborn, A.M, Clore, G.M. Deposit date: 1998-05-20 Release date: 1998-10-14 Last modified: 2011-07-13 Method: SOLUTION NMR Cite: Three-dimensional solution structure of the 44 kDa ectodomain of SIV gp41. EMBO J., 17, 1998
2EZS	SOLUTION NMR STRUCTURE OF ECTODOMAIN OF SIV GP41, MODELS 31-40 OF AN ENSEMBLE OF 40 SIMULATED ANNEALING STRUCTURES Descriptor: GP41 Authors: Caffrey, M, Gronenborn, A.M, Clore, G.M. Deposit date: 1998-05-20 Release date: 1998-10-14 Last modified: 2011-07-13 Method: SOLUTION NMR Cite: Three-dimensional solution structure of the 44 kDa ectodomain of SIV gp41. EMBO J., 17, 1998
2EZR	SOLUTION NMR STRUCTURE OF ECTODOMAIN OF SIV GP41, MODELS 21-30 OF AN ENSEMBLE OF 40 SIMULATED ANNEALING STRUCTURES Descriptor: GP41 Authors: Caffrey, M, Gronenborn, A.M, Clore, G.M. Deposit date: 1998-05-20 Release date: 1998-10-14 Last modified: 2011-07-13 Method: SOLUTION NMR Cite: Three-dimensional solution structure of the 44 kDa ectodomain of SIV gp41. EMBO J., 17, 1998
2EZO	SOLUTION NMR STRUCTURE OF ECTODOMAIN OF SIV GP41, RESTRAINED REGULARIZED MEAN STRUCTURE Descriptor: GP41 Authors: Caffrey, M, Gronenborn, A.M, Clore, G.M. Deposit date: 1998-05-20 Release date: 1998-10-14 Last modified: 2022-03-09 Method: SOLUTION NMR Cite: Three-dimensional solution structure of the 44 kDa ectodomain of SIV gp41. EMBO J., 17, 1998
2EZQ	SOLUTION NMR STRUCTURE OF ECTODOMAIN OF SIV GP41, MODELS 11-20 OF AN ENSEMBLE OF 40 SIMULATED ANNEALING STRUCTURES Descriptor: GP41 Authors: Caffrey, M, Gronenborn, A.M, Clore, G.M. Deposit date: 1998-05-20 Release date: 1998-10-14 Last modified: 2011-07-13 Method: SOLUTION NMR Cite: Three-dimensional solution structure of the 44 kDa ectodomain of SIV gp41. EMBO J., 17, 1998
1DLB	HELICAL INTERACTIONS IN THE HIV-1 GP41 CORE REVEALS STRUCTURAL BASIS FOR THE INHIBITORY ACTIVITY OF GP41 PEPTIDES Descriptor: HIV-1 ENVELOPE GLYCOPROTEIN GP41 Authors: Shu, W, Liu, J, Ji, H, Rading, L, Jiang, S, Lu, M. Deposit date: 1999-12-09 Release date: 1999-12-15 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Helical interactions in the HIV-1 gp41 core reveal structural basis for the inhibitory activity of gp41 peptides. Biochemistry, 39, 2000

 

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