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8U4O
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BU of 8u4o by Molmil
Structure of CXCL12-bound CXCR4/Gi complex
Descriptor: C-X-C chemokine receptor type 4, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Saotome, K, McGoldrick, L.L, Franklin, M.C.
Deposit date:2023-09-11
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Structural insights into CXCR4 modulation and oligomerization
Biorxiv, 2024
8U4R
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BU of 8u4r by Molmil
Structure of REGN7663-Fab bound CXCR4
Descriptor: C-X-C chemokine receptor type 4, CHOLESTEROL, REGN7663 Fab heavy chain, ...
Authors:Saotome, K, McGoldrick, L.L, Franklin, M.C.
Deposit date:2023-09-11
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural insights into CXCR4 modulation and oligomerization
Biorxiv, 2024
8U4P
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BU of 8u4p by Molmil
Structure of AMD3100-bound CXCR4/Gi complex
Descriptor: C-X-C chemokine receptor type 4, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Saotome, K, McGoldrick, L.L, Franklin, M.C.
Deposit date:2023-09-11
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.15 Å)
Cite:Structural insights into CXCR4 modulation and oligomerization
Biorxiv, 2024
8U4Q
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BU of 8u4q by Molmil
Structure of REGN7663 Fab-bound CXCR4/Gi complex
Descriptor: C-X-C chemokine receptor type 4, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Saotome, K, McGoldrick, L.L, Franklin, M.C.
Deposit date:2023-09-11
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:Structural insights into CXCR4 modulation and oligomerization
Biorxiv, 2024
8U4T
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BU of 8u4t by Molmil
Structure of tetrameric CXCR4 in complex with REGN7663 Fab
Descriptor: (2R)-1-(hexadecanoyloxy)-3-(phosphonooxy)propan-2-yl (9Z)-octadec-9-enoate, C-X-C chemokine receptor type 4, CHOLESTEROL, ...
Authors:Saotome, K, McGoldrick, L.L, Franklin, M.C.
Deposit date:2023-09-11
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.38 Å)
Cite:Structural insights into CXCR4 modulation and oligomerization
Biorxiv, 2024
8U4S
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BU of 8u4s by Molmil
Structure of trimeric CXCR4 in complex with REGN7663 Fab
Descriptor: (2R)-1-(hexadecanoyloxy)-3-(phosphonooxy)propan-2-yl (9Z)-octadec-9-enoate, C-X-C chemokine receptor type 4, CHOLESTEROL, ...
Authors:Saotome, K, McGoldrick, L.L, Franklin, M.C.
Deposit date:2023-09-11
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Structural insights into CXCR4 modulation and oligomerization
Biorxiv, 2024
8U4N
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BU of 8u4n by Molmil
Structure of Apo CXCR4/Gi complex
Descriptor: C-X-C chemokine receptor type 4, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Saotome, K, McGoldrick, L.L, Franklin, M.C.
Deposit date:2023-09-11
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (2.72 Å)
Cite:Structural insights into CXCR4 modulation and oligomerization
Biorxiv, 2024
8UNP
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BU of 8unp by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class E)
Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Papasergi-Scott, M.M, Skiniotis, G.
Deposit date:2023-10-19
Release date:2024-03-06
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 2024
8UNW
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BU of 8unw by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class L)
Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Papasergi-Scott, M.M, Skiniotis, G.
Deposit date:2023-10-19
Release date:2024-03-06
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 2024
8UO1
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BU of 8uo1 by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class Q)
Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Papasergi-Scott, M.M, Skiniotis, G.
Deposit date:2023-10-19
Release date:2024-03-06
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 2024
8UNY
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BU of 8uny by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class N)
Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Papasergi-Scott, M.M, Skiniotis, G.
Deposit date:2023-10-19
Release date:2024-03-06
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 2024
8UNM
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BU of 8unm by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class B)
Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Papasergi-Scott, M.M, Skiniotis, G.
Deposit date:2023-10-19
Release date:2024-03-06
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 2024
8UNR
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BU of 8unr by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class G)
Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Papasergi-Scott, M.M, Skiniotis, G.
Deposit date:2023-10-19
Release date:2024-03-06
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 2024
8UNV
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BU of 8unv by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class K)
Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Papasergi-Scott, M.M, Skiniotis, G.
Deposit date:2023-10-19
Release date:2024-03-06
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 2024
8UO3
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BU of 8uo3 by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class S)
Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Papasergi-Scott, M.M, Skiniotis, G.
Deposit date:2023-10-19
Release date:2024-03-06
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 2024
8UNQ
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BU of 8unq by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class F)
Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Papasergi-Scott, M.M, Skiniotis, G.
Deposit date:2023-10-19
Release date:2024-03-06
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 2024
8UNU
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BU of 8unu by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class J)
Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Papasergi-Scott, M.M, Skiniotis, G.
Deposit date:2023-10-19
Release date:2024-03-06
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 2024
8U8F
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BU of 8u8f by Molmil
GPR3 Orphan G-coupled Protein Receptor in complex with Dominant Negative Gs.
Descriptor: G-protein coupled receptor 3, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Russell, I.C, Belousoff, M.J, Sexton, P.
Deposit date:2023-09-17
Release date:2024-03-06
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:Lipid-Dependent Activation of the Orphan G Protein-Coupled Receptor, GPR3.
Biochemistry, 63, 2024
8UNN
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BU of 8unn by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class C)
Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Papasergi-Scott, M.M, Skiniotis, G.
Deposit date:2023-10-19
Release date:2024-03-06
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 2024
8UNS
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BU of 8uns by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class H)
Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Papasergi-Scott, M.M, Skiniotis, G.
Deposit date:2023-10-19
Release date:2024-03-06
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 2024
8UO2
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BU of 8uo2 by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class R)
Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Papasergi-Scott, M.M, Skiniotis, G.
Deposit date:2023-10-19
Release date:2024-03-06
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 2024
8UNX
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BU of 8unx by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class M)
Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Papasergi-Scott, M.M, Skiniotis, G.
Deposit date:2023-10-19
Release date:2024-03-06
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 2024
8UNT
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BU of 8unt by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class I)
Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Papasergi-Scott, M.M, Skiniotis, G.
Deposit date:2023-10-19
Release date:2024-03-06
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 2024
8UNZ
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BU of 8unz by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class O)
Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Papasergi-Scott, M.M, Skiniotis, G.
Deposit date:2023-10-19
Release date:2024-03-06
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 2024
8UO4
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BU of 8uo4 by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class T)
Descriptor: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Papasergi-Scott, M.M, Skiniotis, G.
Deposit date:2023-10-19
Release date:2024-03-06
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 2024

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