PDB: 250 resultsInfo pagesStatus searchChemie searchBIRD

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6I8L	Crystal structure of Spindlin1 in complex with the inhibitor TD001851a Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 5'-(cyclopropylmethoxy)-6'-[3-(1,3-dihydroisoindol-2-yl)propoxy]spiro[cyclopentane-1,3'-indole]-2'-amine, ... Authors: Johansson, C, Fagan, V, Brennan, P.E, Sorrell, F.J, Krojer, T, Arrowsmith, C.H, Bountra, C, Edwards, A, Oppermann, U.C.T. Deposit date: 2018-11-20 Release date: 2018-12-05 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.58 Å) Cite: A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin Function. J.Med.Chem., 62, 2019
6I8B	Crystal structure of Spindlin1 in complex with the inhibitor VinSpinIn Descriptor: 2-[4-[2-[[2-[3-[2-azanyl-5-(cyclopropylmethoxy)-3,3-dimethyl-indol-6-yl]oxypropyl]-1,3-dihydroisoindol-5-yl]oxy]ethyl]-1,2,3-triazol-1-yl]-1-[4-(2-pyrrolidin-1-ylethyl)piperidin-1-yl]ethanone, DIMETHYL SULFOXIDE, GLYCINE, ... Authors: Johansson, C, Fagan, V, Brennan, P.E, Sorrell, F.J, Krojer, T, Arrowsmith, C.H, Bountra, C, Edwards, A, Oppermann, U.C.T. Deposit date: 2018-11-19 Release date: 2018-12-05 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.76 Å) Cite: A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin Function. J.Med.Chem., 62, 2019
5XMY	Crystal structure of TAF3 PHD finger bound to H3K4me3Q5ser Descriptor: Histone peptide H3(1-15)K4me3Q5ser, Transcription initiation factor TFIID subunit 3, ZINC ION Authors: Zhao, S, Zhang, B, Li, H. Deposit date: 2017-05-16 Release date: 2018-11-28 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.699 Å) Cite: Crystal structure of TAF3 PHD finger bound to H3K4me3Q5ser to be published
5Y53	Crystal structure of AL2 PAL domain in complex with AtBMI1b binding site Descriptor: AtBMI1b binding site, PHD finger protein ALFIN-LIKE 2 Authors: Peng, L, Wang, L.L, Huang, Y. Deposit date: 2017-08-07 Release date: 2018-08-15 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.598 Å) Cite: Structural Analysis of the Arabidopsis AL2-PAL and PRC1 Complex Provides Mechanistic Insight into Active-to-Repressive Chromatin State Switch J. Mol. Biol., 430, 2018
6E2H	Crystal structure of human Ash2L (SPRY domain and SDI motif) in complex with full length DPY-30 Descriptor: Protein dpy-30 homolog, Set1/Ash2 histone methyltransferase complex subunit ASH2 Authors: Joshi, M, Brunzelle, J.S, Couture, J.F. Deposit date: 2018-07-11 Release date: 2018-08-08 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.236 Å) Cite: Structural Analysis of the Ash2L/Dpy-30 Complex Reveals a Heterogeneity in H3K4 Methylation. Structure, 26, 2018
5Z8N	Crystal structure of Arabidopsis thaliana EBS C-terminal deletion construct in complex with an H3K4me2 peptide Descriptor: Chromatin remodeling protein EBS, H3K4me2 peptide, ZINC ION Authors: Yang, Z, Du, J. Deposit date: 2018-01-31 Release date: 2018-07-25 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.1 Å) Cite: EBS is a bivalent histone reader that regulates floral phase transition in Arabidopsis. Nat. Genet., 50, 2018
5Z8L	crystal structure of Arabidopsis thaliana EBS in complex with an H3K27me3 peptide Descriptor: Chromatin remodeling protein EBS, H3K27me3 peptide, ZINC ION Authors: Yang, Z, Du, J. Deposit date: 2018-01-31 Release date: 2018-07-25 Last modified: 2018-09-19 Method: X-RAY DIFFRACTION (2.005 Å) Cite: EBS is a bivalent histone reader that regulates floral phase transition in Arabidopsis. Nat. Genet., 50, 2018
5Y21	Crystal structure of AL2 PAL domain in complex with AtRing1a proximal site Descriptor: AtRing1a proximal binding site peptide, PHD finger protein ALFIN-LIKE 2 Authors: Peng, L, Wang, L.L, Huang, Y. Deposit date: 2017-07-22 Release date: 2018-07-25 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.769 Å) Cite: Structural Analysis of the Arabidopsis AL2-PAL and PRC1 Complex Provides Mechanistic Insight into Active-to-Repressive Chromatin State Switch J. Mol. Biol., 430, 2018
5ZNP	Crystal structure of PtSHL in complex with an H3K4me3 peptide Descriptor: 15-mer peptide from Histone H3.2, SHORT LIFE family protein, ZINC ION Authors: Lv, X, Du, J. Deposit date: 2018-04-10 Release date: 2018-07-18 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Dual recognition of H3K4me3 and H3K27me3 by a plant histone reader SHL. Nat Commun, 9, 2018
5ZNR	Crystal structure of PtSHL in complex with an H3K27me3 peptide Descriptor: 17-mer peptide from Histone H3.2, SHORT LIFE family protein, SULFATE ION, ... Authors: Lv, X, Du, J. Deposit date: 2018-04-10 Release date: 2018-07-18 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.202 Å) Cite: Dual recognition of H3K4me3 and H3K27me3 by a plant histone reader SHL. Nat Commun, 9, 2018
5XVW	Crystal structure of AL2 PAL domain in complex with AtRing1a distal site Descriptor: AtRing1a distal binding site, PHD finger protein ALFIN-LIKE 2 Authors: Peng, L, Wang, L.L, Huang, Y. Deposit date: 2017-06-28 Release date: 2018-07-04 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.849 Å) Cite: Structural Analysis of the Arabidopsis AL2-PAL and PRC1 Complex Provides Mechanistic Insight into Active-to-Repressive Chromatin State Switch J. Mol. Biol., 430, 2018
5XVL	Crystal structure of AL2 PAL domain Descriptor: PHD finger protein ALFIN-LIKE 2, SULFATE ION Authors: Peng, L, Wang, L.L, Huang, Y. Deposit date: 2017-06-28 Release date: 2018-07-04 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.629 Å) Cite: Structural Analysis of the Arabidopsis AL2-PAL and PRC1 Complex Provides Mechanistic Insight into Active-to-Repressive Chromatin State Switch J. Mol. Biol., 430, 2018
5XVJ	Crystal structure of AL7 PAL domain Descriptor: PHD finger protein ALFIN-LIKE 7, SULFATE ION Authors: Peng, L, Wang, L.L, Huang, Y. Deposit date: 2017-06-28 Release date: 2018-07-04 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Structural Analysis of the Arabidopsis AL2-PAL and PRC1 Complex Provides Mechanistic Insight into Active-to-Repressive Chromatin State Switch J. Mol. Biol., 430, 2018
5VAR	Crystal structure of KDM4A tandem TUDOR domain in complex with a tri-methyl lysine competitive inhibitor Descriptor: (1R,2S,3R,4S)-3-[(dimethylamino)methyl]-1-phenylbicyclo[2.2.1]heptan-2-ol, Lysine-specific demethylase 4A Authors: Judge, R.A, Upadhyay, A.K. Deposit date: 2017-03-27 Release date: 2018-03-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.83 Å) Cite: Targeting lysine specific demethylase 4A (KDM4A) tandem TUDOR domain - A fragment based approach. Bioorg. Med. Chem. Lett., 28, 2018
5YVX	Crystal structure of SDG8 CW domain in complex with H3K4me1 peptide Descriptor: H3K4me1, Histone-lysine N-methyltransferase ASHH2, ZINC ION Authors: Liu, Y, Huang, Y. Deposit date: 2017-11-27 Release date: 2018-03-14 Last modified: 2018-05-09 Method: X-RAY DIFFRACTION (1.591 Å) Cite: Uncovering the mechanistic basis for specific recognition of monomethylated H3K4 by the CW domain ofArabidopsishistone methyltransferase SDG8. J. Biol. Chem., 293, 2018
5ME8	N-terminal domain of the human tumor suppressor ING5 Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, Inhibitor of growth protein 5 Authors: Roversi, P, Blanco, F.J, Rojas, A.L, Buitrago, J.A.R. Deposit date: 2016-11-14 Release date: 2018-03-14 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3.2 Å) Cite: The Tumor Suppressor ING5 Is a Dimeric, Bivalent Recognition Molecule of the Histone H3K4me3 Mark. J.Mol.Biol., 431, 2019
5WAK	Crystal Structure of a Suz12-Rbbp4 Binary Complex Descriptor: Histone-binding protein RBBP4, Polycomb protein SUZ12, ZINC ION Authors: Chen, S, Jiao, L, Liu, X. Deposit date: 2017-06-26 Release date: 2018-03-14 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Unique Structural Platforms of Suz12 Dictate Distinct Classes of PRC2 for Chromatin Binding. Mol. Cell, 69, 2018
5WAI	Crystal Structure of a Suz12-Rbbp4-Jarid2-Aebp2 Heterotetrameric Complex Descriptor: Histone-binding protein RBBP4, Jumonji, AT-rich interactive domain 2, ... Authors: Chen, S, Jiao, L, Liu, X. Deposit date: 2017-06-26 Release date: 2018-03-14 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Unique Structural Platforms of Suz12 Dictate Distinct Classes of PRC2 for Chromatin Binding. Mol. Cell, 69, 2018
5MTO	N-terminal domain of the human tumor suppressor ING5 C19S mutant Descriptor: Inhibitor of growth protein 5, SODIUM ION, SULFATE ION Authors: Ormaza, G, Buitrago, J.A.R, Roversi, P, Rojas, A.L, Blanco, F.J. Deposit date: 2017-01-10 Release date: 2018-02-28 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3.1 Å) Cite: The Tumor Suppressor ING5 Is a Dimeric, Bivalent Recognition Molecule of the Histone H3K4me3 Mark. J.Mol.Biol., 431, 2019
5YC4	Crystal structure of AL3 PHD finger bound to H3K4me3 Descriptor: Histone H3K4me3, PHD finger protein ALFIN-LIKE 3, ZINC ION Authors: Zhao, S, Zhang, B, Li, H. Deposit date: 2017-09-06 Release date: 2018-01-24 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.697 Å) Cite: Systematic Profiling of Histone Readers in Arabidopsis thaliana. Cell Rep, 22, 2018
5Y20	Crystal structure of AL1 PHD finger bound to H3K4me3 Descriptor: PEPTIDE FROM HISTONE H3, PHD finger protein ALFIN-LIKE 1, ZINC ION Authors: Zhao, S, Zhang, B, Li, H. Deposit date: 2017-07-22 Release date: 2018-01-24 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.409 Å) Cite: Systematic Profiling of Histone Readers in Arabidopsis thaliana. Cell Rep, 22, 2018
5YKN	crystal structure of Arabidopsis thaliana JMJ14 catalytic domain Descriptor: NICKEL (II) ION, Probable lysine-specific demethylase JMJ14, ZINC ION Authors: Yang, Z, Du, J. Deposit date: 2017-10-15 Release date: 2017-12-27 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure of the Arabidopsis JMJ14-H3K4me3 Complex Provides Insight into the Substrate Specificity of KDM5 Subfamily Histone Demethylases. Plant Cell, 30, 2018
5YKO	Crystal structure of Arabidopsis thaliana JMJ14 catalytic domain in complex with NOG and H3K4me3 peptide Descriptor: H3(1-10)K4me3 peptide, N-OXALYLGLYCINE, NICKEL (II) ION, ... Authors: Yang, Z, Du, J. Deposit date: 2017-10-15 Release date: 2017-12-27 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structure of the Arabidopsis JMJ14-H3K4me3 Complex Provides Insight into the Substrate Specificity of KDM5 Subfamily Histone Demethylases. Plant Cell, 30, 2018
5Y5W	Crystal structure of human Spindlin1 in complex with a histone H4K20(me3) peptide Descriptor: Histone peptide H4K20(me3), Spindlin-1 Authors: Wang, C, Zang, J. Deposit date: 2017-08-10 Release date: 2017-10-11 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Spindlin-1 recognizes methylations of K20 and R23 of histone H4 tail FEBS Lett., 592, 2018
5WLE	Crystal structure of the PPS PHD finger in complex with H3K4me3 Descriptor: H3K4me3 Peptide, Protein partner of snf, isoform A, ... Authors: Klein, B.J, Kutateladze, T.G. Deposit date: 2017-07-26 Release date: 2017-10-04 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.952 Å) Cite: A Unique pH-Dependent Recognition of Methylated Histone H3K4 by PPS and DIDO. Structure, 25, 2017

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