PDB: 8 件ウェブページステータス検索Chemie searchBIRD

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4XQ7	The crystal structure of the OAS-like domain (OLD) of human OASL 分子名称: 2'-5'-oligoadenylate synthase-like protein 著者 Ibsen, M.S, Gad, H.H, Andersen, L.L, Hornung, V, Julkunen, I, Sarkar, S.N, Hartmann, R. 登録日 2015-01-19 公開日 2015-04-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural and functional analysis reveals that human OASL binds dsRNA to enhance RIG-I signaling. Nucleic Acids Res., 43, 2015
4S3N	Crystal structure of human OAS3 domain I in complex with dsRNA 分子名称: 2'-5'-oligoadenylate synthase 3, RNA (5'-R(*GP*GP*CP*UP*UP*UP*UP*GP*AP*CP*CP*UP*UP*UP*AP*UP*GP*AP*A)-3'), RNA (5'-R(*UP*UP*CP*AP*UP*AP*AP*AP*GP*GP*UP*CP*AP*AP*AP*AP*GP*CP*C)-3') 著者 Donovan, J, Whitney, G, Rath, S, Korennykh, A. 登録日 2015-02-26 公開日 2015-03-25 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural mechanism of sensing long dsRNA via a noncatalytic domain in human oligoadenylate synthetase 3. Proc.Natl.Acad.Sci.USA, 112, 2015
1PX5	Crystal structure of the 2'-specific and double-stranded RNA-activated interferon-induced antiviral protein 2'-5'-oligoadenylate synthetase 分子名称: 2'-5'-oligoadenylate synthetase 1, SULFATE ION 著者 Hartmann, R, Justesen, J, Sarkar, S.N, Sen, G.C, Yee, V.C. 登録日 2003-07-02 公開日 2003-11-25 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Crystal structure of the 2'-specific and double-stranded RNA-activated interferon-induced antiviral protein 2'-5'-oligoadenylate synthetase Mol.Cell, 12, 2003
4IG8	Structural basis for cytosolic double-stranded RNA surveillance by human OAS1 分子名称: 2'-5'-oligoadenylate synthase 1, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Donovan, J, Korennykh, A. 登録日 2012-12-16 公開日 2013-01-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis for cytosolic double-stranded RNA surveillance by human oligoadenylate synthetase 1. Proc.Natl.Acad.Sci.USA, 110, 2013
4RWP	Crystal structure of porcine OAS1 in complex with dsRNA 分子名称: 2'-5'-oligoadenylate synthase 1, RNA (5'-R(*GP*GP*CP*UP*UP*UP*UP*GP*AP*CP*CP*UP*UP*UP*AP*UP*GP*AP*A)-3'), RNA (5'-R(*UP*UP*CP*AP*UP*AP*AP*AP*GP*GP*UP*CP*AP*AP*AP*AP*GP*CP*C)-3') 著者 Lohoefener, J, Steinke, N, Kay-Fedorov, P, Baruch, P, Nikulin, A, Tishchenko, S, Manstein, D.J, Fedorov, R. 登録日 2014-12-05 公開日 2015-05-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 The Activation Mechanism of 2'-5'-Oligoadenylate Synthetase Gives New Insights Into OAS/cGAS Triggers of Innate Immunity. Structure, 23, 2015
4RWQ	Crystal structure of the apo-state of porcine OAS1 分子名称: 2'-5'-oligoadenylate synthase 1 著者 Lohoefener, J, Steinke, N, Kay-Fedorov, P, Baruch, P, Nikulin, A, Tishchenko, S, Manstein, D.J, Fedorov, R. 登録日 2014-12-05 公開日 2015-05-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 The Activation Mechanism of 2'-5'-Oligoadenylate Synthetase Gives New Insights Into OAS/cGAS Triggers of Innate Immunity. Structure, 23, 2015
4RWN	Crystal structure of the pre-reactive state of porcine OAS1 分子名称: 2'-5'-oligoadenylate synthase 1, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MAGNESIUM ION, ... 著者 Lohoefener, J, Steinke, N, Kay-Fedorov, P, Baruch, P, Nikulin, A, Tishchenko, S, Manstein, D.J, Fedorov, R. 登録日 2014-12-05 公開日 2015-05-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The Activation Mechanism of 2'-5'-Oligoadenylate Synthetase Gives New Insights Into OAS/cGAS Triggers of Innate Immunity. Structure, 23, 2015
4RWO	Crystal structure of the porcine OAS1 L149R mutant in complex with dsRNA and ApCpp in the AMP donor position 分子名称: 2'-5'-oligoadenylate synthase 1, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MAGNESIUM ION, ... 著者 Lohoefener, J, Steinke, N, Kay-Fedorov, P, Baruch, P, Nikulin, A, Tishchenko, S, Manstein, D.J, Fedorov, R. 登録日 2014-12-05 公開日 2015-05-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The Activation Mechanism of 2'-5'-Oligoadenylate Synthetase Gives New Insights Into OAS/cGAS Triggers of Innate Immunity. Structure, 23, 2015