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2L95
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Solution Structure of Cytotoxic T-Lymphocyte Antigent-2(Ctla protein), Crammer at pH 6.0
分子名称: Crammer
著者Tseng, T.S, Cheng, C.S, Liu, Y.N, Lyu, P.C.
登録日2011-01-31
公開日2011-12-21
最終更新日2020-01-01
実験手法SOLUTION NMR
主引用文献A molten globule-to-ordered structure transition of Drosophila melanogaster crammer is required for its ability to inhibit cathepsin.
Biochem.J., 442, 2012
5JT8
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BU of 5jt8 by Molmil
Structural basis for the limited antibody cross reactivity between the mite allergens Blo t 1 and Der p 1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Blo t 1 allergen, ...
著者Meno, K, Kastrup, J.S, Gajhede, M.
登録日2016-05-09
公開日2017-05-24
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The structure of the mite allergen Blo t 1 explains the limited antibody cross-reactivity to Der p 1.
Allergy, 72, 2017
8GX2
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BU of 8gx2 by Molmil
The crystal structure of human CtsL in complex with 14c
分子名称: DIMETHYL SULFOXIDE, N-[(2S)-3-cyclohexyl-1-[[(2S,3S)-4-(cyclopropylamino)-3-oxidanyl-4-oxidanylidene-1-[(3S)-2-oxidanylidenepiperidin-3-yl]butan-2-yl]amino]-1-oxidanylidene-propan-2-yl]-1-benzofuran-2-carboxamide, Procathepsin L
著者Zhao, Y, Shao, M, Zhao, J, Yang, H, Rao, Z.
登録日2022-09-18
公開日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The crystal structure of human CtsL in complex with 14a
To Be Published
1BY8
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BU of 1by8 by Molmil
THE CRYSTAL STRUCTURE OF HUMAN PROCATHEPSIN K
分子名称: PROTEIN (PROCATHEPSIN K)
著者Lalonde, J.M, Zhao, B, Smith, W.W, Janson, C.A, Desjarlais, R.L, Tomaszek, T.A, Carr, T.J, Thompson, S.K, Yamashita, D.S, Veber, D.F, Abdel-Mequid, S.S.
登録日1998-10-27
公開日1999-10-24
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The crystal structure of human procathepsin K.
Biochemistry, 38, 1999
7AVM
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BU of 7avm by Molmil
Crystal Structure of Pro-Rhodesain C150A
分子名称: Cysteine protease, GLYCEROL
著者Johe, P, Jaenicke, E, Neuweiler, H, Schirmeister, T, Kersten, C, Hellmich, U.
登録日2020-11-05
公開日2020-11-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure, interdomain dynamics, and pH-dependent autoactivation of pro-rhodesain, the main lysosomal cysteine protease from African trypanosomes.
J.Biol.Chem., 296, 2021
6U7D
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BU of 6u7d by Molmil
Recombinant stem bromelain precursor
分子名称: FBSB
著者Yongqing, T, Pike, R.N, Wijeyewickrema, L.C.
登録日2019-09-02
公開日2019-09-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal Structure of a Recombinant Stem Bromelain Precursor
To be published
2O6X
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Crystal Structure of ProCathepsin L1 from Fasciola hepatica
分子名称: Secreted cathepsin L 1
著者Brinen, L.S, Dalton, J.P, Geiger, S, Marion, R, Stack, C.M.
登録日2006-12-08
公開日2007-12-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural and functional relationships in the virulence-associated cathepsin L proteases of the parasitic liver fluke, Fasciola hepatica.
J.Biol.Chem., 283, 2008
1PCI
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PROCARICAIN
分子名称: PROCARICAIN
著者Groves, M.R, Taylor, M.A.J, Scott, M, Cummings, N.J, Pickersgill, R.W, Jenkins, J.A.
登録日1996-06-28
公開日1997-04-01
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The prosequence of procaricain forms an alpha-helical domain that prevents access to the substrate-binding cleft.
Structure, 4, 1996
5Z5O
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Structure of Pycnonodysostosis disease related I249T mutant of human cathepsin K
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, CHLORIDE ION, ...
著者Biswas, S, Roy, S.
登録日2018-01-19
公開日2018-09-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Not all pycnodysostosis-related mutants of human cathepsin K are inactive - crystal structure and biochemical studies of an active mutant I249T.
FEBS J., 285, 2018
2C0Y
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BU of 2c0y by Molmil
THE CRYSTAL STRUCTURE OF A CYS25ALA MUTANT OF HUMAN PROCATHEPSIN S
分子名称: PROCATHEPSIN S
著者Kaulmann, G, Palm, G.J, Schilling, K, Hilgenfeld, R, Wiederanders, B.
登録日2005-09-08
公開日2006-11-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Crystal Structure of a Cys25 -> Ala Mutant of Human Procathepsin S Elucidates Enzyme-Prosequence Interactions.
Protein Sci., 15, 2006
3F75
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Activated Toxoplasma gondii cathepsin L (TgCPL) in complex with its propeptide
分子名称: 1,2-ETHANEDIOL, BROMIDE ION, CHLORIDE ION, ...
著者Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日2008-11-07
公開日2008-11-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Toxoplasma gondii cathepsin L is the primary target of the invasion-inhibitory compound morpholinurea-leucyl-homophenyl-vinyl sulfone phenyl.
J.Biol.Chem., 284, 2009
1CS8
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CRYSTAL STRUCTURE OF PROCATHEPSIN L
分子名称: HUMAN PROCATHEPSIN L
著者Cygler, M, Coulombe, R.
登録日1999-08-17
公開日1999-08-23
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment.
EMBO J., 15, 1996
6CZS
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Crystal structure of human pro-cathepsin H C26S mutant
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Pro-cathepsin H, ...
著者Huang, X, Hao, Y.
登録日2018-04-09
公開日2018-08-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Crystal structures of human procathepsin H.
PLoS ONE, 13, 2018
1CJL
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CRYSTAL STRUCTURE OF A CYSTEINE PROTEASE PROFORM
分子名称: PROCATHEPSIN L
著者Coulombe, R, Grochulski, P, Sivaraman, J, Cygler, M.
登録日1996-07-24
公開日1997-08-12
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment.
EMBO J., 15, 1996
6CZK
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BU of 6czk by Molmil
Crystal structure of wild-type human pro-cathepsin H
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Pro-cathepsin H, ...
著者Huang, X, Hao, Y.
登録日2018-04-09
公開日2018-08-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Crystal structures of human procathepsin H.
PLoS ONE, 13, 2018
7W33
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BU of 7w33 by Molmil
The crystal structure of human CtsL in complex with 14a
分子名称: N-[(2S)-3-(4-fluorophenyl)-1-oxidanylidene-1-[[(2R,3S)-3-oxidanyl-4-oxidanylidene-1-[(3S)-2-oxidanylidenepiperidin-3-yl]-4-[(phenylmethyl)amino]butan-2-yl]amino]propan-2-yl]-1-benzofuran-2-carboxamide, Procathepsin L
著者Zhao, Y, Shao, M, Zhao, J, Yang, H, Rao, Z.
登録日2021-11-25
公開日2023-05-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献The crystal structure of human CtsL in complex with 14a
To Be Published
7W34
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The crystal structure of human CtsL in complex with 14b
分子名称: N-[(2S)-3-cyclohexyl-1-oxidanylidene-1-[[(2S,3S)-3-oxidanyl-4-oxidanylidene-1-[(3S)-2-oxidanylidenepiperidin-3-yl]-4-[(phenylmethyl)amino]butan-2-yl]amino]propan-2-yl]-1-benzofuran-2-carboxamide, Procathepsin L
著者Zhao, Y, Shao, M, Zhao, J, Yang, H, Rao, Z.
登録日2021-11-25
公開日2023-05-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献The crystal structure of human CtsL in complex with 14a
To Be Published
3TNX
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Structure of the precursor of a thermostable variant of papain at 2.6 Angstroem resolution
分子名称: CHLORIDE ION, Papain
著者Roy, S, Choudhury, D, Dattagupta, J.K, Biswas, S.
登録日2011-09-02
公開日2012-09-12
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献The structure of a thermostable mutant of pro-papain reveals its activation mechanism
Acta Crystallogr.,Sect.D, 68, 2012
3USV
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Structure of the precursor of a thermostable variant of papain at 3.8 A resolution from a crystal soaked at pH 4
分子名称: Papain
著者Roy, S, Choudhury, D, Biswas, S, Dattagupta, J.K.
登録日2011-11-24
公開日2012-11-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Crystallographic analysis of pro-papain variant elucidates the structural basis of the step-wise activation mechanism of the zymogen
To be Published
5EGW
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BU of 5egw by Molmil
2.70 A crystal structure of the Amb a 11 cysteine protease, a major ragweed pollen allergen, in its proform
分子名称: Cysteine protease
著者Briozzo, P, Kopecny, D.
登録日2015-10-27
公開日2016-04-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural and Functional Characterization of the Major Allergen Amb a 11 from Short Ragweed Pollen.
J.Biol.Chem., 291, 2016
5EF4
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2.05 A crystal structure of the Amb a 11 cysteine protease, a major ragweed pollen allergen, in its proform
分子名称: Cysteine protease, GLYCEROL
著者Briozzo, P, Kopecny, D, Savko, M.
登録日2015-10-23
公開日2016-04-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural and Functional Characterization of the Major Allergen Amb a 11 from Short Ragweed Pollen.
J.Biol.Chem., 291, 2016
6JD8
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Structure of a proline specific mutant of human cathepsin L
分子名称: 1,2-ETHANEDIOL, Cathepsin L1, DI(HYDROXYETHYL)ETHER, ...
著者Choudhury, D, Biswas, S.
登録日2019-01-31
公開日2020-02-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.457 Å)
主引用文献Structure-guided protein engineering of human cathepsin L for efficient collagenolytic activity.
Protein Eng.Des.Sel., 34, 2021
6JD0
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Structure of mutant human cathepsin L, engineered for GAG binding
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Cathepsin L1, ...
著者Choudhury, D, Biswas, S.
登録日2019-01-30
公開日2020-02-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.805 Å)
主引用文献Structure-guided protein engineering of human cathepsin L for efficient collagenolytic activity.
Protein Eng.Des.Sel., 34, 2021
3QT4
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Structure of digestive procathepsin L 3 of Tenebrio molitor larval midgut
分子名称: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, Cathepsin-L-like midgut cysteine proteinase, PHOSPHATE ION, ...
著者Beton, D, Guzzo, C.R, Terra, W.R, Farah, C.S.
登録日2011-02-22
公開日2012-02-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献The 3D structure and function of digestive cathepsin L-like proteinases of Tenebrio molitor larval midgut.
Insect Biochem.Mol.Biol., 42, 2012
3QJ3
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Structure of digestive procathepsin L2 proteinase from Tenebrio molitor larval midgut
分子名称: ACETATE ION, Cathepsin L-like protein
著者Beton, D, Guzzo, C.R, Terra, W.R, Farah, C.S.
登録日2011-01-28
公開日2012-02-01
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The 3D structure and function of digestive cathepsin L-like proteinases of Tenebrio molitor larval midgut.
Insect Biochem.Mol.Biol., 42, 2012

 

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