8THN
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1F6G
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6FIZ
| Crystal Structure of CNG mimicking NaK-EAPP mutant (T67A) cocrystallized with K+ | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCINE, POTASSIUM ION, ... | 著者 | Napolitano, L.M.R, De March, M, Steiner, R.A, Onesti, S. | 登録日 | 2018-01-19 | 公開日 | 2019-03-06 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | Crystal Structure of CNG mimicking NaK-EAPP mutant (T67A) cocrystallized with K+ To Be Published
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4BW5
| Crystal structure of human two pore domain potassium ion channel TREK2 (K2P10.1) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CADMIUM ION, POTASSIUM CHANNEL SUBFAMILY K MEMBER 10, ... | 著者 | Pike, A.C.W, Dong, Y.Y, Dong, L, Quigley, A, Shrestha, L, Mukhopadhyay, S, Strain-Damerell, C, Goubin, S, Grieben, M, Shintre, C.A, Mackenzie, A, Vollmar, M, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Burgess-Brown, N, Carpenter, E.P. | 登録日 | 2013-06-30 | 公開日 | 2013-07-31 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | K2P Channel Gating Mechanisms Revealed by Structures of Trek-2 and a Complex with Prozac Science, 347, 2015
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1BL8
| POTASSIUM CHANNEL (KCSA) FROM STREPTOMYCES LIVIDANS | 分子名称: | POTASSIUM ION, PROTEIN (POTASSIUM CHANNEL PROTEIN) | 著者 | Doyle, D.A, Cabral, J.M, Pfuetzner, R.A, Kuo, A, Gulbis, J.M, Cohen, S.L, Chait, B.T, Mackinnon, R. | 登録日 | 1998-07-23 | 公開日 | 1998-07-29 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | The structure of the potassium channel: molecular basis of K+ conduction and selectivity. Science, 280, 1998
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5J9P
| KcsA in vitro | 分子名称: | Fab, POTASSIUM ION, pH-gated potassium channel KcsA | 著者 | Matulef, K, Valiyaveetil, F.I. | 登録日 | 2016-04-10 | 公開日 | 2016-07-20 | 最終更新日 | 2019-12-04 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Combining in Vitro Folding with Cell Free Protein Synthesis for Membrane Protein Expression. Biochemistry, 55, 2016
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1ZWI
| Structure of mutant KcsA potassium channel | 分子名称: | DIACYL GLYCEROL, NONAN-1-OL, POTASSIUM ION, ... | 著者 | Cordero-Morales, J.F, Cuello, L.G, Zhao, Y, Jogini, V, Cortes, D.M, Roux, B, Perozo, E. | 登録日 | 2005-06-03 | 公開日 | 2006-03-07 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Molecular determinants of gating at the potassium-channel selectivity filter. Nat.Struct.Mol.Biol., 13, 2006
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8DE9
| Cryo-EM structure of the zebrafish two pore domain K+ channel TREK1 (K2P2.1) in DDM/POPE mixed micelles | 分子名称: | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, POTASSIUM ION, Potassium channel, ... | 著者 | Schmidpeter, P.A.M, Nimigean, C.M, Riegelhaupt, P.M. | 登録日 | 2022-06-20 | 公開日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Membrane phospholipids control gating of the mechanosensitive potassium leak channel TREK1. Nat Commun, 14, 2023
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8DE8
| Cryo-EM structure of the zebrafish two pore domain K+ channel TREK1 (K2P2.1) in DDM/POPA mixed micelles | 分子名称: | (2R)-1-(hexadecanoyloxy)-3-(phosphonooxy)propan-2-yl (9Z)-octadec-9-enoate, POTASSIUM ION, Potassium channel, ... | 著者 | Schmidpeter, P.A.M, Nimigean, C.M, Riegelhaupt, P.M. | 登録日 | 2022-06-20 | 公開日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (2.82 Å) | 主引用文献 | Membrane phospholipids control gating of the mechanosensitive potassium leak channel TREK1. Nat Commun, 14, 2023
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8DE7
| Cryo-EM structure of the zebrafish two pore domain K+ channel TREK1 (K2P2.1) in DDM detergent | 分子名称: | DODECYL-BETA-D-MALTOSIDE, POTASSIUM ION, Potassium channel, ... | 著者 | Schmidpeter, P.A.M, Nimigean, C.M, Riegelhaupt, P.M. | 登録日 | 2022-06-20 | 公開日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | 主引用文献 | Membrane phospholipids control gating of the mechanosensitive potassium leak channel TREK1. Nat Commun, 14, 2023
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6RV3
| Crystal structure of the human two pore domain potassium ion channel TASK-1 (K2P3.1) in a closed conformation with a bound inhibitor BAY 1000493 | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL HEMISUCCINATE, DECYL-BETA-D-MALTOPYRANOSIDE, ... | 著者 | Rodstrom, K.E.J, Pike, A.C.W, Zhang, W, Quigley, A, Speedman, D, Mukhopadhyay, S.M.M, Shrestha, L, Chalk, R, Venkaya, S, Bushell, S.R, Tessitore, A, Burgess-Brown, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | 登録日 | 2019-05-30 | 公開日 | 2019-08-07 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | A lower X-gate in TASK channels traps inhibitors within the vestibule. Nature, 582, 2020
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6RV4
| Crystal structure of the human two pore domain potassium ion channel TASK-1 (K2P3.1) in a closed conformation with a bound inhibitor BAY 2341237 | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL HEMISUCCINATE, POTASSIUM ION, ... | 著者 | Rodstrom, K.E.J, Pike, A.C.W, Zhang, W, Quigley, A, Speedman, D, Mukhopadhyay, S.M.M, Shrestha, L, Chalk, R, Venkaya, S, Bushell, S.R, Tessitore, A, Burgess-Brown, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | 登録日 | 2019-05-30 | 公開日 | 2019-08-07 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | A lower X-gate in TASK channels traps inhibitors within the vestibule. Nature, 582, 2020
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6RV2
| Crystal structure of the human two pore domain potassium ion channel TASK-1 (K2P3.1) in a closed conformation | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL HEMISUCCINATE, DECYL-BETA-D-MALTOPYRANOSIDE, ... | 著者 | Rodstrom, K.E.J, Pike, A.C.W, Zhang, W, Quigley, A, Speedman, D, Mukhopadhyay, S.M.M, Shrestha, L, Chalk, R, Venkaya, S, Bushell, S.R, Tessitore, A, Burgess-Brown, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | 登録日 | 2019-05-30 | 公開日 | 2019-08-07 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | A lower X-gate in TASK channels traps inhibitors within the vestibule. Nature, 582, 2020
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5VKH
| Closed conformation of KcsA Y82A-F103A mutant | 分子名称: | (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, Antibody Heavy Chain, Antibody Light Chain, ... | 著者 | Cuello, L.G, Perozo, E, Cortes, D.M. | 登録日 | 2017-04-21 | 公開日 | 2017-12-06 | 最終更新日 | 2020-01-01 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | The gating cycle of a K+ channel at atomic resolution. Elife, 6, 2017
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5VK6
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5VKE
| Open conformation of KcsA deep-inactivated | 分子名称: | (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, Antibody Heavy Chain, Antibody Light Chain, ... | 著者 | Cuello, L.G, Perozo, E, Cortes, D.M. | 登録日 | 2017-04-21 | 公開日 | 2017-12-06 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | The gating cycle of a K+ channel at atomic resolution. Elife, 6, 2017
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6U9Z
| Wild-type MthK pore in 6 mM K+ | 分子名称: | Calcium-gated potassium channel MthK, HEXANE-1,6-DIOL, POTASSIUM ION | 著者 | Posson, D.J, Nimigean, C.M. | 登録日 | 2019-09-09 | 公開日 | 2020-11-04 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.954 Å) | 主引用文献 | Selectivity filter ion binding affinity determines inactivation in a potassium channel. Proc.Natl.Acad.Sci.USA, 117, 2020
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6U9Y
| Wild-type MthK pore in 11 mM K+ | 分子名称: | Calcium-gated potassium channel MthK, HEXANE-1,6-DIOL, POTASSIUM ION | 著者 | Posson, D.J, Nimigean, C.M. | 登録日 | 2019-09-09 | 公開日 | 2020-11-04 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Selectivity filter ion binding affinity determines inactivation in a potassium channel. Proc.Natl.Acad.Sci.USA, 117, 2020
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5EBW
| KcsA with G77ester mutation | 分子名称: | Antibody Fab Fragment Light Chain, DIACYL GLYCEROL, NONAN-1-OL, ... | 著者 | Matulef, K, Valiyaveetil, F.I. | 登録日 | 2015-10-19 | 公開日 | 2016-04-20 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Individual Ion Binding Sites in the K(+) Channel Play Distinct Roles in C-type Inactivation and in Recovery from Inactivation. Structure, 24, 2016
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5EC2
| KcsA with V76ester+G77dA mutations | 分子名称: | Antibody Fab Fragment Light Chain, DIACYL GLYCEROL, NONAN-1-OL, ... | 著者 | Matulef, K, Valiyaveetil, F.I. | 登録日 | 2015-10-20 | 公開日 | 2016-04-20 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Individual Ion Binding Sites in the K(+) Channel Play Distinct Roles in C-type Inactivation and in Recovery from Inactivation. Structure, 24, 2016
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5EBM
| KcsA T75G mutant in the nonconductive state | 分子名称: | Antibody Fab Fragment Light Chain, DIACYL GLYCEROL, NONAN-1-OL, ... | 著者 | Matulef, K, Valiyaveetil, F.I. | 登録日 | 2015-10-19 | 公開日 | 2016-04-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Individual Ion Binding Sites in the K(+) Channel Play Distinct Roles in C-type Inactivation and in Recovery from Inactivation. Structure, 24, 2016
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5E1A
| Structure of KcsA with L24C/R117C mutations | 分子名称: | POTASSIUM ION, antibody Fab fragment heavy chain, antibody Fab fragment light chain, ... | 著者 | Upadhyay, V, Kim, D.M, Nimigean, C.M. | 登録日 | 2015-09-29 | 公開日 | 2016-07-13 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Conformational heterogeneity in closed and open states of the KcsA potassium channel in lipid bicelles. J.Gen.Physiol., 148, 2016
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5EBL
| KcsA T75G in the Conductive State | 分子名称: | Antibody Fab Fragment Light Chain, DIACYL GLYCEROL, NONAN-1-OL, ... | 著者 | Matulef, K, Valiyaveetil, F.I. | 登録日 | 2015-10-19 | 公開日 | 2016-04-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Individual Ion Binding Sites in the K(+) Channel Play Distinct Roles in C-type Inactivation and in Recovery from Inactivation. Structure, 24, 2016
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5EC1
| KcsA with V76ester mutation | 分子名称: | Antibody Fab Fragment Light Chain, DIACYL GLYCEROL, NONAN-1-OL, ... | 著者 | Matulef, K, Valiyaveetil, F.I. | 登録日 | 2015-10-20 | 公開日 | 2016-04-20 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Individual Ion Binding Sites in the K(+) Channel Play Distinct Roles in C-type Inactivation and in Recovery from Inactivation. Structure, 24, 2016
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1S5H
| Potassium Channel Kcsa-Fab Complex T75C mutant in K+ | 分子名称: | ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, DIACYL GLYCEROL, ... | 著者 | Mackinnon, R, Zhou, M. | 登録日 | 2004-01-20 | 公開日 | 2004-05-18 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | A mutant KcsA K(+) channel with altered conduction properties and selectivity filter ion distribution. J.Mol.Biol., 338, 2004
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