1AGW
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1BYG
| KINASE DOMAIN OF HUMAN C-TERMINAL SRC KINASE (CSK) IN COMPLEX WITH INHIBITOR STAUROSPORINE | 分子名称: | PROTEIN (C-TERMINAL SRC KINASE), STAUROSPORINE | 著者 | Antson, A.A, Lamers, M.B.A.C, Scott, R.K, Williams, D.H, Hubbard, R.E. | 登録日 | 1998-10-14 | 公開日 | 1999-10-14 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of the protein tyrosine kinase domain of C-terminal Src kinase (CSK) in complex with staurosporine. J.Mol.Biol., 285, 1999
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1FPU
| CRYSTAL STRUCTURE OF ABL KINASE DOMAIN IN COMPLEX WITH A SMALL MOLECULE INHIBITOR | 分子名称: | N-[4-METHYL-3-[[4-(3-PYRIDINYL)-2-PYRIMIDINYL]AMINO]PHENYL]-3-PYRIDINECARBOXAMIDE, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL | 著者 | Schindler, T, Bornmann, W, Pellicena, P, Miller, W.T, Clarkson, B, Kuriyan, J. | 登録日 | 2000-08-31 | 公開日 | 2000-09-20 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural mechanism for STI-571 inhibition of abelson tyrosine kinase. Science, 289, 2000
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1FGK
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1FGI
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1GAG
| CRYSTAL STRUCTURE OF THE INSULIN RECEPTOR KINASE IN COMPLEX WITH A BISUBSTRATE INHIBITOR | 分子名称: | BISUBSTRATE PEPTIDE INHIBITOR, INSULIN RECEPTOR, TYROSINE KINASE DOMAIN, ... | 著者 | Parang, K, Till, J.H, Ablooglu, A.J, Kohanski, R.A, Hubbard, S.R, Cole, P.A. | 登録日 | 2000-11-29 | 公開日 | 2001-01-17 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Mechanism-based design of a protein kinase inhibitor. Nat.Struct.Biol., 8, 2001
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1FVR
| TIE2 KINASE DOMAIN | 分子名称: | TYROSINE-PROTEIN KINASE TIE-2 | 著者 | Shewchuk, L.M, Hassell, A.M, Ellis, B, Holmes, W.D, Davis, R, Horne, E.L, Kadwell, S.H, McKee, D.D, Moore, J.T. | 登録日 | 2000-09-20 | 公開日 | 2001-09-20 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of the Tie2 RTK domain: self-inhibition by the nucleotide binding loop, activation loop, and C-terminal tail. Structure Fold.Des., 8, 2000
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1GJO
| The FGFr2 tyrosine kinase domain | 分子名称: | FIBROBLAST GROWTH FACTOR RECEPTOR 2, SULFATE ION | 著者 | Ceska, T.A, Owens, R, Doyle, C, Hamlyn, P, Crabbe, T, Moffat, D, Davis, J, Martin, R, Perry, M.J. | 登録日 | 2001-07-31 | 公開日 | 2003-08-15 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The Fgfr2 Tyrosine Kinase Domain To be Published
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1I44
| CRYSTALLOGRAPHIC STUDIES OF AN ACTIVATION LOOP MUTANT OF THE INSULIN RECEPTOR TYROSINE KINASE | 分子名称: | INSULIN RECEPTOR, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | 著者 | Till, J.H, Ablooglu, A.J, Frankel, M, Kohanski, R.A, Hubbard, S.R. | 登録日 | 2001-02-19 | 公開日 | 2001-03-07 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystallographic and solution studies of an activation loop mutant of the insulin receptor tyrosine kinase: insights into kinase mechanism. J.Biol.Chem., 276, 2001
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1IEP
| CRYSTAL STRUCTURE OF THE C-ABL KINASE DOMAIN IN COMPLEX WITH STI-571. | 分子名称: | 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, CHLORIDE ION, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL | 著者 | Nagar, B, Bornmann, W, Schindler, T, Clarkson, B, Kuriyan, J. | 登録日 | 2001-04-10 | 公開日 | 2001-04-18 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structures of the kinase domain of c-Abl in complex with the small molecule inhibitors PD173955 and imatinib (STI-571) Cancer Res., 62, 2002
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1IR3
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1IRK
| CRYSTAL STRUCTURE OF THE TYROSINE KINASE DOMAIN OF THE HUMAN INSULIN RECEPTOR | 分子名称: | ETHYL MERCURY ION, INSULIN RECEPTOR TYROSINE KINASE DOMAIN | 著者 | Hubbard, S.R, Wei, L, Ellis, L, Hendrickson, W.A. | 登録日 | 1995-01-02 | 公開日 | 1995-02-27 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of the tyrosine kinase domain of the human insulin receptor. Nature, 372, 1994
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1K2P
| Crystal structure of Bruton's tyrosine kinase domain | 分子名称: | Tyrosine-protein kinase BTK | 著者 | Mao, C, Zhou, M, Uckun, F.M. | 登録日 | 2001-09-28 | 公開日 | 2002-06-26 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of Bruton's tyrosine kinase domain suggests a novel pathway for activation and provides insights into the molecular basis of X-linked agammaglobulinemia. J.Biol.Chem., 276, 2001
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1JQH
| IGF-1 receptor kinase domain | 分子名称: | IGF-1 receptor kinase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Pautsch, A, Zoephel, A, Ahorn, H, Spevak, W, Hauptmann, R, Nar, H. | 登録日 | 2001-08-07 | 公開日 | 2002-04-19 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of bisphosphorylated IGF-1 receptor kinase: insight into domain movements upon kinase activation. Structure, 9, 2001
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1K3A
| Structure of the Insulin-like Growth Factor 1 Receptor Kinase | 分子名称: | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, insulin receptor substrate 1, insulin-like growth factor 1 receptor | 著者 | Favelyukis, S, Till, J.H, Hubbard, S.R, Miller, W.T. | 登録日 | 2001-10-02 | 公開日 | 2001-11-28 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure and autoregulation of the insulin-like growth factor 1 receptor kinase. Nat.Struct.Biol., 8, 2001
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1LUF
| Crystal Structure of the MuSK Tyrosine Kinase: Insights into Receptor Autoregulation | 分子名称: | muscle-specific tyrosine kinase receptor musk | 著者 | Till, J.H, Becerra, M, Watty, A, Lu, Y, Ma, Y, Neubert, T.A, Burden, S.J, Hubbard, S.R. | 登録日 | 2002-05-22 | 公開日 | 2002-09-11 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Crystal structure of the MuSK tyrosine kinase: insights into receptor autoregulation. Structure, 10, 2002
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1M7N
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1M17
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1M14
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1MP8
| Crystal structure of Focal Adhesion Kinase (FAK) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, focal adhesion kinase 1 | 著者 | Nowakowski, J, Cronin, C.N, McRee, D.E, Knuth, M.W, Nelson, C.G, Pavletich, N.P, Rodgers, J, Sang, B.-C, Scheibe, D.N, Swanson, R.V, Thompson, D.A. | 登録日 | 2002-09-11 | 公開日 | 2003-09-16 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structures of the cancer-related Aurora-A, FAK, and EphA2 protein kinases from nanovolume crystallography Structure, 10, 2002
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1M52
| Crystal Structure of the c-Abl Kinase domain in complex with PD173955 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-(2,6-DICHLORO-PHENYL)-8-METHYL-2-(3-METHYLSULFANYL-PHENYLAMINO)-8H-PYRIDO[2,3-D]PYRIMIDIN-7-ONE, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1 | 著者 | Nagar, B, Bornmann, W, Pellicena, P, Schindler, T, Veach, D, Miller, W.T, Clarkson, B, Kuriyan, J. | 登録日 | 2002-07-08 | 公開日 | 2002-09-18 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal Structures of the Kinase Domain of c-Abl in Complex with the Small Molecule Inhibitors PD173955 and Imatinib (STI-571) Cancer Res., 62, 2002
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1MQB
| Crystal Structure of Ephrin A2 (ephA2) Receptor Protein Kinase | 分子名称: | Ephrin type-A receptor 2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | 著者 | Nowakowski, J, Cronin, C.N, McRee, D.E, Knuth, M.W, Nelson, C, Pavletich, N, Rogers, J, Sang, B.C, Scheibe, D.N, Swanson, R.V, Thompson, D.A. | 登録日 | 2002-09-16 | 公開日 | 2003-09-16 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structures of the Cancer Related Aurora-A, FAK and EphA2 Protein Kinases from Nanovolume Crystallography Structure, 10, 2003
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1U4D
| Structure of the ACK1 Kinase Domain bound to Debromohymenialdisine | 分子名称: | Activated CDC42 kinase 1, CHLORIDE ION, DEBROMOHYMENIALDISINE | 著者 | Lougheed, J.C, Chen, R.H, Mak, P, Stout, T.J. | 登録日 | 2004-07-23 | 公開日 | 2004-08-31 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structures of the Phosphorylated and Unphosphorylated Kinase Domains of the Cdc42-associated Tyrosine Kinase ACK1. J.Biol.Chem., 279, 2004
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1U46
| Crystal Structure of the Unphosphorylated Kinase Domain of the Tyrosine Kinase ACK1 | 分子名称: | Activated CDC42 kinase 1, CHLORIDE ION | 著者 | Lougheed, J.C, Chen, R.H, Mak, P, Stout, T.J. | 登録日 | 2004-07-23 | 公開日 | 2004-08-31 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structures of the Phosphorylated and Unphosphorylated Kinase Domains of the Cdc42-associated Tyrosine Kinase ACK1. J.Biol.Chem., 279, 2004
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1U59
| Crystal Structure of the ZAP-70 Kinase Domain in Complex with Staurosporine | 分子名称: | STAUROSPORINE, Tyrosine-protein kinase ZAP-70 | 著者 | Jin, L, Pluskey, S, Petrella, E.C, Cantin, S.M, Gorga, J.C, Rynkiewicz, M.J, Pandey, P, Strickler, J.E, Babine, R.E, Weaver, D.T, Seidl, K.J. | 登録日 | 2004-07-27 | 公開日 | 2004-08-17 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The Three-dimensional Structure of the ZAP-70 Kinase Domain in Complex with Staurosporine: IMPLICATIONS FOR THE DESIGN OF SELECTIVE INHIBITORS J.Biol.Chem., 279, 2004
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