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1LR7
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Crystal structure of Fs1, the heparin-binding domain of follistatin, complexed with the heparin analogue sucrose octasulphate (SOS)
分子名称: SULFATE ION, follistatin
著者Innis, C.A, Hyvonen, M.
登録日2002-05-15
公開日2003-07-29
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal Structures of the Heparan Sulfate-binding Domain of Follistatin: Insights into ligand binding.
J.Biol.Chem., 278, 2003
1YU6
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Crystal Structure of the Subtilisin Carlsberg:OMTKY3 Complex
分子名称: CALCIUM ION, Ovomucoid, Subtilisin Carlsberg
著者Maynes, J.T, Cherney, M.M, Qasim, M.A, Laskowski Jr, M, James, M.N.G.
登録日2005-02-11
公開日2005-05-03
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structure of the subtilisin Carlsberg-OMTKY3 complex reveals two different ovomucoid conformations.
Acta Crystallogr.,Sect.D, 61, 2005
1Z7K
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BU of 1z7k by Molmil
Crystal Structure of Trypsin- Ovomucoid turkey egg white inhibitor complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ovomucoid, Trypsin
著者Syed Ibrahim, B, Pattabhi, V.
登録日2005-03-25
公開日2005-04-05
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of trypsin-turkey egg white inhibitor complex
Biochem.Biophys.Res.Commun., 313, 2004
2ARP
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BU of 2arp by Molmil
Activin A in complex with Fs12 fragment of follistatin
分子名称: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, Follistatin, GLYCEROL, ...
著者Harrington, A.E, Morris-Triggs, S.A, Ruotolo, B.T, Robinson, C.V, Ohnuma, S, Hyvonen, M.
登録日2005-08-21
公開日2006-03-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for the inhibition of activin signalling by follistatin
Embo J., 25, 2006
3PIS
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BU of 3pis by Molmil
Crystal Structure of Carcinoscorpius rotundicauda Serine Protease Inhibitor Domain 1
分子名称: Kazal-type serine protease inhibitor SPI-1
著者Giri, P.K, Tang, X.H, Sivaraman, J.
登録日2010-11-08
公開日2010-12-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Modifying the Substrate Specificity of Carcinoscorpius rotundicauda Serine Protease Inhibitor Domain 1 to Target Thrombin
To be Published
3TJQ
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BU of 3tjq by Molmil
N-domain of HtrA1
分子名称: CHLORIDE ION, GLYCEROL, PLATINUM (II) ION, ...
著者Eigenbrot, C, Ultsch, M.
登録日2011-08-24
公開日2012-05-16
最終更新日2012-06-27
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Structural and Functional Analysis of HtrA1 and Its Subdomains.
Structure, 20, 2012
1LR8
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BU of 1lr8 by Molmil
Crystal structure of Fs1, the heparin-binding domain of follistatin, complexed with the heparin analogue D-myo-inositol hexasulphate (Ins6S)
分子名称: D-MYO-INOSITOL-HEXASULPHATE, Follistatin
著者Innis, C.A, Hyvonen, M.
登録日2002-05-15
公開日2003-07-29
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structures of the Heparan Sulfate-binding Domain of Follistatin: Insights into ligand binding.
J.Biol.Chem., 278, 2003
3HH2
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BU of 3hh2 by Molmil
Crystal structure of the myostatin:follistatin 288 complex
分子名称: CITRIC ACID, Follistatin, Growth/differentiation factor 8, ...
著者Cash, J.N, Thompson, T.B.
登録日2009-05-14
公開日2009-08-04
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The structure of myostatin:follistatin 288: insights into receptor utilization and heparin binding
Embo J., 28, 2009
7KBU
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BU of 7kbu by Molmil
Structure of Hevin FS-EC
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
著者Machius, M, Fan, S, Rudenko, G.
登録日2020-10-03
公開日2021-02-10
最終更新日2021-07-14
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Interplay between hevin, SPARC, and MDGAs: Modulators of neurexin-neuroligin transsynaptic bridges.
Structure, 29, 2021
7Q6C
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BU of 7q6c by Molmil
complement C6 FIM1-2 bound to CP010 antibody
分子名称: ACETATE ION, CP010 heavy chain, CP010 light chain, ...
著者Olesen, H.G, Andersen, G.R.
登録日2021-11-06
公開日2022-05-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.29274 Å)
主引用文献Development, Characterization, and in vivo Validation of a Humanized C6 Monoclonal Antibody that Inhibits the Membrane Attack Complex.
J Innate Immun, 2022
6JZA
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BU of 6jza by Molmil
Structure of Fstl1
分子名称: Follistatin-related protein 1
著者Liu, X, Ning, W.
登録日2019-04-30
公開日2019-08-21
最終更新日2019-09-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and functional study of FK domain of Fstl1.
Protein Sci., 28, 2019
5JHW
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BU of 5jhw by Molmil
Crystal Structure of the GDF11:Follistatin 288 complex
分子名称: CITRATE ANION, Follistatin, Growth/differentiation factor 11, ...
著者Walker, R.G, Thompson, T.B.
登録日2016-04-21
公開日2017-03-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural basis for potency differences between GDF8 and GDF11.
BMC Biol., 15, 2017
3SEK
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BU of 3sek by Molmil
Crystal Structure of the Myostatin:Follistatin-like 3 Complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Follistatin-related protein 3, Growth/differentiation factor 8
著者Cash, J.N, Thompson, T.B.
登録日2011-06-10
公開日2011-11-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.401 Å)
主引用文献Structure of myostatinfollistatin-like 3: N-terminal domains of follistatin-type molecules exhibit alternate modes of binding.
J.Biol.Chem., 287, 2012
3B4V
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BU of 3b4v by Molmil
X-Ray structure of Activin in complex with FSTL3
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Inhibin beta A chain, ...
著者Thompson, T.B.
登録日2007-10-24
公開日2008-09-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献The structure of FSTL3.activin A complex. Differential binding of N-terminal domains influences follistatin-type antagonist specificity.
J.Biol.Chem., 283, 2008
1LR9
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BU of 1lr9 by Molmil
STRUCTURE OF Fs1, THE HEPARIN-BINDING DOMAIN OF FOLLISTATIN
分子名称: Follistatin
著者Innis, C.A, Hyvonen, M.
登録日2002-05-15
公開日2003-07-29
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structures of the Heparan Sulfate-binding Domain of Follistatin: Insights into ligand binding.
J.Biol.Chem., 278, 2003
3QTL
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BU of 3qtl by Molmil
Structural Basis for Dual-inhibition Mechanism of a Non-classical Kazal-type Serine Protease Inhibitor from Horseshoe Crab in Complex with Subtilisin
分子名称: Kazal-type serine protease inhibitor SPI-1, Subtilisin-like serin protease
著者Shenoy, R.T, Sivaraman, J.
登録日2011-02-23
公開日2011-06-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for dual-inhibition mechanism of a non-classical kazal-type serine protease inhibitor from horseshoe crab in complex with subtilisin.
Plos One, 6, 2011
1TBR
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BU of 1tbr by Molmil
CRYSTAL STRUCTURE OF INSECT DERIVED DOUBLE DOMAIN KAZAL INHIBITOR RHODNIIN IN COMPLEX WITH THROMBIN
分子名称: RHODNIIN, THROMBIN
著者Van De Locht, A, Lamba, D, Bode, W.
登録日1995-03-03
公開日1996-10-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Two heads are better than one: crystal structure of the insect derived double domain Kazal inhibitor rhodniin in complex with thrombin.
EMBO J., 14, 1995
2B0U
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BU of 2b0u by Molmil
The Structure of the Follistatin:Activin Complex
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Follistatin, IRIDIUM (III) ION, ...
著者Thompson, T.B, Lerch, T.F, Cook, R.W, Woodruff, T.K, Jardetzky, T.S.
登録日2005-09-14
公開日2005-10-11
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Structure of the Follistatin:Activin Complex Reveals Antagonism of Both Type I and Type II Receptor Binding.
Dev.Cell, 9, 2005
3T5O
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BU of 3t5o by Molmil
Crystal Structure of human Complement Component C6
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, Complement component C6, ...
著者Aleshin, A.E, Stec, B, Bankston, L.A, DiScipio, R.G, Liddington, R.C.
登録日2011-07-27
公開日2012-02-01
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.869 Å)
主引用文献Structure of Complement C6 Suggests a Mechanism for Initiation and Unidirectional, Sequential Assembly of Membrane Attack Complex (MAC).
J.Biol.Chem., 287, 2012
7EEB
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BU of 7eeb by Molmil
Structure of the CatSpermasome
分子名称: (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Wu, J.P, Ke, M.
登録日2021-03-18
公開日2021-07-28
最終更新日2021-08-11
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure of a mammalian sperm cation channel complex.
Nature, 595, 2021
8K6L
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Cryo-EM structure of human OATP1B1 in complex with DCF
分子名称: 2',7'-bis(chloranyl)-3',6'-bis(oxidanyl)spiro[2-benzofuran-3,9'-xanthene]-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Shan, Z, Yang, X, Zhang, Y.
登録日2023-07-25
公開日2023-09-13
最終更新日2023-12-20
実験手法ELECTRON MICROSCOPY (2.92 Å)
主引用文献Cryo-EM structures of human organic anion transporting polypeptide OATP1B1.
Cell Res., 33, 2023
8PG0
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Human OATP1B3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, BICARBONATE ION, CHOLESTEROL, ...
著者Ciuta, A.-D, Nosol, K, Kowal, J, Mukherjee, S, Ramirez, A.S, Stieger, B, Kossiakoff, A.A, Locher, K.P.
登録日2023-06-17
公開日2023-09-27
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Structure of human drug transporters OATP1B1 and OATP1B3.
Nat Commun, 14, 2023
8B0F
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CryoEM structure of C5b8-CD59
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Bubeck, D, Couves, E.C, Gardner, S.
登録日2022-09-07
公開日2023-02-22
最終更新日2023-03-01
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis for membrane attack complex inhibition by CD59.
Nat Commun, 14, 2023
1TBQ
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CRYSTAL STRUCTURE OF INSECT DERIVED DOUBLE DOMAIN KAZAL INHIBITOR RHODNIIN IN COMPLEX WITH THROMBIN
分子名称: RHODNIIN, THROMBIN
著者Van De Locht, A, Lamba, D, Bode, W.
登録日1995-03-02
公開日1996-10-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Two heads are better than one: crystal structure of the insect derived double domain Kazal inhibitor rhodniin in complex with thrombin.
EMBO J., 14, 1995
8HND
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BU of 8hnd by Molmil
Cryo-EM structure of human OATP1B1 in complex with estrone-3-sulfate
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Solute carrier organic anion transporter family member 1B1, ...
著者Shan, Z, Yang, X, Liu, H, Nan, J, Yuan, Y, Zhang, Y.
登録日2022-12-07
公開日2023-09-13
最終更新日2023-12-20
実験手法ELECTRON MICROSCOPY (3.19 Å)
主引用文献Cryo-EM structures of human organic anion transporting polypeptide OATP1B1.
Cell Res., 33, 2023

 

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