7Q6C
 
 | | complement C6 FIM1-2 bound to CP010 antibody | | 分子名称: | ACETATE ION, CP010 heavy chain, CP010 light chain, ... | | 著者 | Olesen, H.G, Andersen, G.R. | | 登録日 | 2021-11-06 | | 公開日 | 2022-05-25 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.29274 Å) | | 主引用文献 | Development, Characterization, and in vivo Validation of a Humanized C6 Monoclonal Antibody that Inhibits the Membrane Attack Complex.
J Innate Immun, 2022
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2N17
 | | NMR structure of a Kazal-type serine protease inhibitor from the subterranean termite defense gland of Coptotermes formosanus Shiraki soldiers | | 分子名称: | Lysozyme-Protease Inhibitor Protein | | 著者 | Negulescu, H, Guo, Y, Garner, T.P, Goodwin, O.Y, Henderson, G, Laine, R.A, Macnaughtan, M.A. | | 登録日 | 2015-03-23 | | 公開日 | 2015-05-06 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A Kazal-Type Serine Protease Inhibitor from the Defense Gland Secretion of the Subterranean Termite Coptotermes formosanus Shiraki.
Plos One, 10, 2015
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3PIS
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6JZA
 | | Structure of Fstl1 | | 分子名称: | Follistatin-related protein 1 | | 著者 | Liu, X, Ning, W. | | 登録日 | 2019-04-30 | | 公開日 | 2019-08-21 | | 最終更新日 | 2019-09-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural and functional study of FK domain of Fstl1.
Protein Sci., 28, 2019
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7KBU
 | | Structure of Hevin FS-EC | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Machius, M, Fan, S, Rudenko, G. | | 登録日 | 2020-10-03 | | 公開日 | 2021-02-10 | | 最終更新日 | 2021-07-14 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | Interplay between hevin, SPARC, and MDGAs: Modulators of neurexin-neuroligin transsynaptic bridges.
Structure, 29, 2021
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2KCX
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1LR7
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1LR8
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1LR9
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3B4V
 | | X-Ray structure of Activin in complex with FSTL3 | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Inhibin beta A chain, ... | | 著者 | Thompson, T.B. | | 登録日 | 2007-10-24 | | 公開日 | 2008-09-02 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | The structure of FSTL3.activin A complex. Differential binding of N-terminal domains influences follistatin-type antagonist specificity.
J.Biol.Chem., 283, 2008
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3HH2
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5JHW
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4E0S
 | | Crystal Structure of C5b-6 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement C5, ... | | 著者 | Aleshin, A.E, Stec, B, DiScipio, R, Liddington, R.C. | | 登録日 | 2012-03-05 | | 公開日 | 2012-04-18 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (4.21 Å) | | 主引用文献 | Crystal structure of c5b-6 suggests structural basis for priming assembly of the membrane attack complex.
J.Biol.Chem., 287, 2012
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7EEB
 | | Structure of the CatSpermasome | | 分子名称: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Wu, J.P, Ke, M. | | 登録日 | 2021-03-18 | | 公開日 | 2021-07-28 | | 最終更新日 | 2021-08-11 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structure of a mammalian sperm cation channel complex.
Nature, 595, 2021
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8S9P
 | | 1:1:1 agrin/LRP4/MuSK complex | | 分子名称: | Agrin, Low-density lipoprotein receptor-related protein 4, Muscle, ... | | 著者 | Xie, T, Xu, G.J, Liu, Y, Quade, B, Lin, W.C, Bai, X.C. | | 登録日 | 2023-03-29 | | 公開日 | 2023-05-17 | | 最終更新日 | 2023-06-14 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structural insights into the assembly of the agrin/LRP4/MuSK signaling complex.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8TZP
 | | Structure of human Wnt7a bound to WLS and RECK | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, PALMITOLEIC ACID, Protein Wnt-7a, ... | | 著者 | Qi, X, Hu, Q, Li, X. | | 登録日 | 2023-08-27 | | 公開日 | 2023-10-18 | | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | | 主引用文献 | Structure of human Wnt7a bound to WLS and RECK
To Be Published
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2B0U
 | | The Structure of the Follistatin:Activin Complex | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Follistatin, IRIDIUM (III) ION, ... | | 著者 | Thompson, T.B, Lerch, T.F, Cook, R.W, Woodruff, T.K, Jardetzky, T.S. | | 登録日 | 2005-09-14 | | 公開日 | 2005-10-11 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The Structure of the Follistatin:Activin Complex Reveals Antagonism of Both Type I and Type II Receptor Binding.
Dev.Cell, 9, 2005
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2ARP
 | | Activin A in complex with Fs12 fragment of follistatin | | 分子名称: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, Follistatin, GLYCEROL, ... | | 著者 | Harrington, A.E, Morris-Triggs, S.A, Ruotolo, B.T, Robinson, C.V, Ohnuma, S, Hyvonen, M. | | 登録日 | 2005-08-21 | | 公開日 | 2006-03-07 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis for the inhibition of activin signalling by follistatin
Embo J., 25, 2006
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2P6A
 | | The structure of the Activin:Follistatin 315 complex | | 分子名称: | Follistatin, Inhibin beta A chain, probable fragment of follistatin | | 著者 | Lerch, T.F, Shimasaki, S, Woodruff, T.K, Jardetzky, T.S. | | 登録日 | 2007-03-16 | | 公開日 | 2007-04-03 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structural and biophysical coupling of heparin and activin binding to follistatin isoform functions.
J.Biol.Chem., 282, 2007
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7NYC
 | | cryoEM structure of 3C9-sMAC | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Menny, A, Couves, E.C, Bubeck, D. | | 登録日 | 2021-03-22 | | 公開日 | 2021-10-06 | | 最終更新日 | 2021-11-17 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural basis of soluble membrane attack complex packaging for clearance.
Nat Commun, 12, 2021
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7NYD
 | | cryoEM structure of 2C9-sMAC | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Menny, A, Couves, E.C, Bubeck, D. | | 登録日 | 2021-03-22 | | 公開日 | 2021-10-06 | | 最終更新日 | 2021-11-17 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural basis of soluble membrane attack complex packaging for clearance.
Nat Commun, 12, 2021
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6H03
 | | OPEN CONFORMATION OF THE MEMBRANE ATTACK COMPLEX | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5,Complement C5, ... | | 著者 | Menny, A, Serna, M, Boyd, C.M, Gardner, S, Joseph, A.P, Topf, M, Bubeck, D. | | 登録日 | 2018-07-06 | | 公開日 | 2018-12-19 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (5.6 Å) | | 主引用文献 | CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers.
Nat Commun, 9, 2018
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6H04
 | | Closed conformation of the Membrane Attack Complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C5,Complement C5, ... | | 著者 | Menny, A, Serna, M, Boyd, C.M, Gardner, S, Joseph, A.P, Topf, M, Bubeck, D. | | 登録日 | 2018-07-06 | | 公開日 | 2018-12-19 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (5.6 Å) | | 主引用文献 | CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers.
Nat Commun, 9, 2018
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3QTL
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1YU6
 | | Crystal Structure of the Subtilisin Carlsberg:OMTKY3 Complex | | 分子名称: | CALCIUM ION, Ovomucoid, Subtilisin Carlsberg | | 著者 | Maynes, J.T, Cherney, M.M, Qasim, M.A, Laskowski Jr, M, James, M.N.G. | | 登録日 | 2005-02-11 | | 公開日 | 2005-05-03 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Structure of the subtilisin Carlsberg-OMTKY3 complex reveals two different ovomucoid conformations.
Acta Crystallogr.,Sect.D, 61, 2005
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