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1B0X
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THE CRYSTAL STRUCTURE OF AN EPH RECEPTOR SAM DOMAIN REVEALS A MECHANISM FOR MODULAR DIMERIZATION.
分子名称: PROTEIN (EPHA4 RECEPTOR TYROSINE KINASE)
著者Stapleton, D, Balan, I, Pawson, T, Sicheri, F.
登録日1998-11-14
公開日1999-05-03
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The crystal structure of an Eph receptor SAM domain reveals a mechanism for modular dimerization.
Nat.Struct.Biol., 6, 1999
6QWV
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SARM1 SAM1-2 domains
分子名称: 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, ...
著者Sporny, M, Isupov, N.M, Opatowsky, Y.
登録日2019-03-06
公開日2019-07-03
最終更新日2019-09-18
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献Structural Evidence for an Octameric Ring Arrangement of SARM1.
J.Mol.Biol., 431, 2019
1KW4
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Polyhomeotic SAM domain structure
分子名称: Polyhomeotic
著者Kim, C.A, Gingery, M, M Pilpa, R, Bowie, J.U.
登録日2002-01-28
公開日2002-06-05
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The SAM domain of polyhomeotic forms a helical polymer.
Nat.Struct.Biol., 9, 2002
1COK
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STRUCTURE OF THE C-TERMINAL DOMAIN OF P73
分子名称: PROTEIN (SECOND SPLICE VARIANT P73)
著者Chi, S.-W, Ayed, A, Arrowsmith, C.H.
登録日1999-05-28
公開日1999-08-17
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of a conserved C-terminal domain of p73 with structural homology to the SAM domain.
EMBO J., 18, 1999
1DXS
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Crystal structure of the C-terminal sterile alpha motif (SAM) domain of human p73 alpha splice variant
分子名称: P53-LIKE TRANSCRIPTION FACTOR
著者Wang, W.K, Chen, Y.W.
登録日2000-01-15
公開日2001-01-12
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Structure of the C-Terminal Sterile Alpha-Motif (Sam) Domain of Human P73 Alpha
Acta Crystallogr.,Sect.D, 57, 2001
1V38
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Solution structure of the Sterile Alpha Motif (SAM) domain of mouse SAMSN1
分子名称: SAM-domain protein SAMSN-1
著者Goroncy, A, Kigawa, T, Koshiba, S, Kobayashi, N, Tochio, N, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2003-10-29
公開日2004-04-29
最終更新日2022-12-21
実験手法SOLUTION NMR
主引用文献Solution structure of the Sterile Alpha Motif (SAM) domain of mouse SAMSN1
To be Published
7Z72
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Crystal structure of p63 SAM in complex with darpin A5
分子名称: DI(HYDROXYETHYL)ETHER, Darpin A5, Isoform 9 of Tumor protein 63
著者Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC)
登録日2022-03-14
公開日2022-07-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Designed Ankyrin Repeat Proteins as a tool box for analyzing p63.
Cell Death Differ., 29, 2022
2Y9U
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Structural basis of p63a SAM domain mutants involved in AEC syndrome
分子名称: SULFATE ION, TUMOR PROTEIN 63
著者Sathyamurthy, A, Freund, S.M.V, Johnson, C.M, Allen, M.D.
登録日2011-02-16
公開日2011-08-03
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural Basis of P63Alpha Sam Domain Mutants Involved in Aec Syndrome.
FEBS J., 278, 2011
5JU5
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Crystal structure of the human Tankyrase 1 (TNKS) SAM domain (D1055R), crystal form 1
分子名称: Tankyrase-1
著者Guetter, S, Mariotti, L, Cronin, N.
登録日2016-05-10
公開日2016-08-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Tankyrase Requires SAM Domain-Dependent Polymerization to Support Wnt-beta-Catenin Signaling.
Mol.Cell, 63, 2016
5JTI
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Crystal structure of the human Tankyrase 1 (TNKS) SAM domain (D1055R), crystal form 2
分子名称: Tankyrase-1
著者Guetter, S, Mariotti, L, Cronin, N.
登録日2016-05-09
公開日2016-08-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Tankyrase Requires SAM Domain-Dependent Polymerization to Support Wnt-beta-Catenin Signaling.
Mol.Cell, 63, 2016
2Y9T
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Structural basis of p63a SAM domain mutants involved in AEC syndrome
分子名称: TUMOR PROTEIN 63
著者Sathyamurthy, A, Freund, S.M.V, Johnson, C.M, Allen, M.D.
登録日2011-02-16
公開日2011-08-03
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural Basis of P63Alpha Sam Domain Mutants Involved in Aec Syndrome.
FEBS J., 278, 2011
1X9X
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Solution Structure of Dimeric SAM Domain from MAPKKK Ste11
分子名称: Serine/threonine-protein kinase STE11
著者Bhattacharjya, S, Xu, P, Gingras, R, Shaykhutdinov, R, Wu, C, Whiteway, M, Ni, F.
登録日2004-08-24
公開日2005-08-30
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Solution structure of the dimeric SAM domain of MAPKKK Ste11 and its interactions with the adaptor protein Ste50 from the budding yeast: implications for Ste11 activation and signal transmission through the Ste50-Ste11 complex.
J.Mol.Biol., 344, 2004
5JRT
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Crystal structure of the human Tankyrase 2 (TNKS2) SAM domain (DH902/924RE)
分子名称: Tankyrase-2
著者Guettler, S, Mariotti, L, Cronin, N.
登録日2016-05-06
公開日2016-08-03
最終更新日2016-08-17
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Tankyrase Requires SAM Domain-Dependent Polymerization to Support Wnt-beta-Catenin Signaling.
Mol.Cell, 63, 2016
5KNI
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Crystal Structure of the wild-type SAM domain of human Tankyrase-1
分子名称: Tankyrase-1
著者Pascal, J.M, McCauley, M, Langelier, M.F, Riccio, A.A.
登録日2016-06-28
公開日2016-08-31
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Tankyrase Sterile alpha Motif Domain Polymerization Is Required for Its Role in Wnt Signaling.
Structure, 24, 2016
6O0S
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Crystal structure of the tandem SAM domains from human SARM1
分子名称: Sterile alpha and TIR motif-containing protein 1
著者Horsefield, S, Burdett, H, Zhang, X, Manik, M.K, Shi, Y, Chen, J, Tiancong, Q, Gilley, J, Lai, J, Gu, W, Rank, M, Deerain, N, Casey, L, Ericsson, D.J, Foley, G, Hughes, R.O, Bosanac, T, von Itzstein, M, Rathjen, J.P, Nanson, J.D, Boden, M, Dry, I.B, Williams, S.J, Staskawicz, B.J, Coleman, M.P, Ve, T, Dodds, P.N, Kobe, B.
登録日2019-02-17
公開日2019-09-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献NAD+cleavage activity by animal and plant TIR domains in cell death pathways.
Science, 365, 2019
6O0T
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Crystal structure of selenomethionine labelled tandem SAM domains (L446M:L505M:L523M mutant) from human SARM1
分子名称: Sterile alpha and TIR motif-containing protein 1
著者Horsefield, S, Burdett, H, Zhang, X, Manik, M.K, Shi, Y, Chen, J, Tiancong, Q, Gilley, J, Lai, J, Gu, W, Rank, M, Deerain, N, Casey, L, Ericsson, D.J, Foley, G, Hughes, R.O, Bosanac, T, von Itzstein, M, Rathjen, J.P, Nanson, J.D, Boden, M, Dry, I.B, Williams, S.J, Staskawicz, B.J, Coleman, M.P, Ve, T, Dodds, P.N, Kobe, B.
登録日2019-02-17
公開日2019-09-04
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献NAD+cleavage activity by animal and plant TIR domains in cell death pathways.
Science, 365, 2019
3H8M
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SAM domain of human ephrin type-a receptor 7 (EPHA7)
分子名称: Ephrin type-A receptor 7
著者Walker, J.R, Yermekbayeva, L, Butler-Cole, C, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2009-04-29
公開日2009-05-26
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献SAM Domain of Human Ephrin Type-A Receptor 7 (Epha7)
To be Published
1OW5
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NMR structure of the Saccharomyces cerevisiae SAM (Sterile Alpha Motif) domain
分子名称: Serine/threonine-protein kinase STE11
著者Donaldson, L.W.
登録日2003-03-28
公開日2004-04-06
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献The solution structure of the S.cerevisiae Ste11 MAPKKK SAM domain and its partnership with Ste50.
J.Mol.Biol., 342, 2004
6ZG1
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SARM1 SAM1-2 domains
分子名称: 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, ...
著者Sporny, M, Guez-Haddad, J, Khazma, T, Yaron, A, Dessau, M, Mim, C, Isupov, M.N, Zalk, R, Hons, M, Opatowsky, Y.
登録日2020-06-18
公開日2020-11-11
最終更新日2020-12-09
実験手法ELECTRON MICROSCOPY (3.77 Å)
主引用文献Structural basis for SARM1 inhibition and activation under energetic stress.
Elife, 9, 2020
6PW7
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X-ray crystal structure of C. elegans STIM EF-SAM domain
分子名称: CALCIUM ION, Stromal interaction molecule 1
著者Enomoto, M, Nishikawa, T, Back, S.I, Ishiyama, N, Zheng, L, Stathopulos, P.B, Ikura, M.
登録日2019-07-22
公開日2019-11-13
最終更新日2020-02-12
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Coordination of a Single Calcium Ion in the EF-hand Maintains the Off State of the Stromal Interaction Molecule Luminal Domain.
J.Mol.Biol., 432, 2020
5N2O
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Structure Of P63 SAM Domain L514F Mutant Causative Of AEC Syndrome
分子名称: Tumor protein 63
著者Rinnenthal, J, Wuerz, J.M, Osterburg, C, Guentert, P, Doetsch, V.
登録日2017-02-08
公開日2018-02-07
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Protein aggregation of the p63 transcription factor underlies severe skin fragility in AEC syndrome.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1RG6
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Solution structure of the C-terminal domain of p63
分子名称: second splice variant p63
著者Cadot, B, Candi, E, Cicero, D.O, Desideri, A, Mele, S, Melino, G, Paci, M.
登録日2003-11-11
公開日2004-11-23
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Solution structure of the C-terminal domain of p63
To be Published
3BS7
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Crystal structure of the Sterile Alpha Motif (SAM) domain of Hyphen/Aveugle
分子名称: Protein aveugle
著者Rajakulendran, T, Sicheri, F.
登録日2007-12-22
公開日2008-02-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献CNK and HYP form a discrete dimer by their SAM domains to mediate RAF kinase signaling.
Proc.Natl.Acad.Sci.USA, 105, 2008
3BQ7
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SAM domain of Diacylglycerol Kinase delta1 (E35G)
分子名称: Diacylglycerol kinase delta
著者Knight, M.J, Bowie, J.U, Sawaya, M.R.
登録日2007-12-19
公開日2008-03-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Regulation of Enzyme Localization by Polymerization: Polymer Formation by the SAM Domain of Diacylglycerol Kinase delta1
Structure, 16, 2008
2B6G
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RNA recognition by the Vts1 SAM domain
分子名称: 5'-R(*GP*GP*AP*GP*GP*CP*UP*CP*UP*GP*GP*CP*AP*GP*CP*UP*UP*UP*C)-3', Vts1p
著者Donaldson, L.W, Johnson, P.E.
登録日2005-10-01
公開日2006-01-24
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献RNA recognition by the Vts1p SAM domain
Nat.Struct.Mol.Biol., 13, 2006

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