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2BDE
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BU of 2bde by Molmil
Crystal Structure of the cytosolic IMP-GMP specific 5'-nucleotidase (lpg0095) from Legionella pneumophila, Northeast Structural Genomics Target LgR1
分子名称: SULFATE ION, cytosolic IMP-GMP specific 5'-nucleotidase
著者Forouhar, F, Abashidze, M, Ho, C.K, Conover, K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2005-10-20
公開日2005-12-06
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal Structure of the cytosolic IMP-GMP specific 5'-nucleotidase (lpg0095) from Legionella pneumophila, Northeast Structural Genomics Target LgR1
To be Published
2J2C
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BU of 2j2c by Molmil
Crystal structure of Human Cytosolic 5'-Nucleotidase II (NT5C2, cN-II)
分子名称: CYTOSOLIC PURINE 5'-NUCLEOTIDASE, GLYCEROL, MAGNESIUM ION, ...
著者Wallden, K, Stenmark, P, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg Schiavone, L, Hogbom, M, Karlberg, T, Kotenyova, T, Loppnau, P, Magnusdottir, A, Nilsson-Ehle, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Sundstrom, M, Uppenberg, J, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Welin, M, Nordlund, P.
登録日2006-08-16
公開日2006-09-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of Human Cytosolic 5'- Nucleotidase II: Insights Into Allosteric Regulation and Substrate Recognition
J.Biol.Chem., 282, 2007
2JC9
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Crystal structure of Human Cytosolic 5'-Nucleotidase II in complex with adenosine
分子名称: ADENOSINE, CYTOSOLIC PURINE 5'-NUCLEOTIDASE, GLYCEROL, ...
著者Wallden, K, Stenmark, P, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg, S.L, Hogbom, M, Karlberg, T, Kotenyova, T, Magnusdottir, A, Nilsson-Ehle, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Sundstrom, M, Uppenberg, J, Thorsell, A.G, Van Den Berg, S, Loppnau, P, Weigelt, J, Welin, M, Nordlund, P.
登録日2006-12-21
公開日2007-01-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal Structure of Human Cytosolic 5'-Nucleotidase II: Insights Into Allosteric Regulation and Substrate Recognition
J.Biol.Chem., 282, 2007
2JCM
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BU of 2jcm by Molmil
Crystal structure of Human Cytosolic 5'-Nucleotidase II in complex with beryllium trifluoride
分子名称: CYTOSOLIC PURINE 5'-NUCLEOTIDASE, MAGNESIUM ION, SULFATE ION, ...
著者Wallden, K, Stenmark, P, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg Schiavone, L, Hogbom, M, Karlberg, T, Kotenyova, T, Magnusdottir, A, Nilsson-Ehle, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Sundstrom, M, Uppenberg, J, Thorsell, A.G, Van Den Berg, S, Loppnau, P, Weigelt, J, Welin, M, Nordlund, P.
登録日2006-12-27
公開日2007-01-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal Structure of Human Cytosolic 5'- Nucleotidase II: Insights Into Allosteric Regulation and Substrate Recognition
J.Biol.Chem., 282, 2007
2XCV
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BU of 2xcv by Molmil
Crystal structure of the D52N variant of cytosolic 5'-nucleotidase II in complex with inosine monophosphate and 2,3-bisphosphoglycerate
分子名称: (2R)-2,3-diphosphoglyceric acid, CYTOSOLIC PURINE 5'-NUCLEOTIDASE, GLYCEROL, ...
著者Wallden, K, Nordlund, P.
登録日2010-04-26
公開日2011-03-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis for the Allosteric Regulation and Substrate Recognition of Human Cytosolic 5'-Nucleotidase II
J.Mol.Biol., 408, 2011
2XCW
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BU of 2xcw by Molmil
Crystal structure of the D52N variant of cytosolic 5'-nucleotidase II in complex with inosine monophosphate and ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CYTOSOLIC PURINE 5'-NUCLEOTIDASE, GLYCEROL, ...
著者Wallden, K, Nordlund, P.
登録日2010-04-26
公開日2011-03-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Basis for the Allosteric Regulation and Substrate Recognition of Human Cytosolic 5'-Nucleotidase II
J.Mol.Biol., 408, 2011
2XCX
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Crystal structure of the apoform of the D52N variant of cytosolic 5'- nucleotidase II
分子名称: CYTOSOLIC PURINE 5'-NUCLEOTIDASE, GLYCEROL
著者Wallden, K, Nordlund, P.
登録日2010-04-26
公開日2011-03-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis for the Allosteric Regulation and Substrate Recognition of Human Cytosolic 5'-Nucleotidase II
J.Mol.Biol., 408, 2011
2XJB
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BU of 2xjb by Molmil
Crystal structure of the D52N variant of cytosolic 5'-nucleotidase II in complex with deoxyguanosine monophosphate and deoxyadenosine triphosphate
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, CYTOSOLIC PURINE 5'-NUCLEOTIDASE, ...
著者Wallden, K, Nordlund, P.
登録日2010-07-03
公開日2011-03-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis for the Allosteric Regulation and Substrate Recognition of Human Cytosolic 5'-Nucleotidase II
J.Mol.Biol., 408, 2011
2XJC
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BU of 2xjc by Molmil
Crystal structure of the D52N variant of cytosolic 5'-nucleotidase II in complex with guanosine monophosphate and diadenosine tetraphosphate
分子名称: BIS(ADENOSINE)-5'-TETRAPHOSPHATE, CYTOSOLIC PURINE 5'-NUCLEOTIDASE, GLYCEROL, ...
著者Wallden, K, Nordlund, P.
登録日2010-07-03
公開日2011-03-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for the Allosteric Regulation and Substrate Recognition of Human Cytosolic 5'-Nucleotidase II
J.Mol.Biol., 408, 2011
2XJD
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BU of 2xjd by Molmil
Crystal structure of the D52N variant of cytosolic 5'-nucleotidase II in complex with inorganic phosphate and deoxyadenosine triphosphate
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CYTOSOLIC PURINE 5'-NUCLEOTIDASE, GLYCEROL, ...
著者Wallden, K, Nordlund, P.
登録日2010-07-04
公開日2011-04-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for the Allosteric Regulation and Substrate Recognition of Human Cytosolic 5'-Nucleotidase II.
J.Mol.Biol., 408, 2011
2XJE
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BU of 2xje by Molmil
Crystal structure of the D52N variant of cytosolic 5'-nucleotidase II in complex with uridine 5'-monophosphate and adenosine triphosphate
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CYTOSOLIC PURINE 5'-NUCLEOTIDASE, GLYCEROL, ...
著者Wallden, K, Nordlund, P.
登録日2010-07-04
公開日2011-03-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis for the Allosteric Regulation and Substrate Recognition of Human Cytosolic 5'-Nucleotidase II
J.Mol.Biol., 408, 2011
2XJF
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BU of 2xjf by Molmil
Crystal structure of the D52N variant of cytosolic 5'-nucleotidase II with a covalently modified Asn52
分子名称: (2R)-2,3-diphosphoglyceric acid, CYTOSOLIC PURINE 5'-NUCLEOTIDASE, GLYCEROL
著者Wallden, K, Nordlund, P.
登録日2010-07-04
公開日2011-03-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis for the Allosteric Regulation and Substrate Recognition of Human Cytosolic 5'-Nucleotidase II
J.Mol.Biol., 408, 2011
4G63
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BU of 4g63 by Molmil
Crystal structure of cytosolic IMP-GMP specific 5'-nucleotidase (lpg0095) in complex with phosphate ions from Legionella pneumophila, Northeast Structural Genomics Consortium Target LgR1
分子名称: Cytosolic IMP-GMP specific 5'-nucleotidase, PHOSPHATE ION
著者Forouhar, F, Abashidze, M, Seetharaman, J, Ho, C.K, Ciccosanti, C, Mao, L, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2012-07-18
公開日2012-10-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Allosteric regulation and substrate activation in cytosolic nucleotidase II from Legionella pneumophila.
Febs J., 281, 2014
4H4B
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BU of 4h4b by Molmil
Human cytosolic 5'-nucleotidase II in complex with Anthraquinone-2,6- disulfonic acid
分子名称: 9,10-dioxo-9,10-dihydroanthracene-2,6-disulfonic acid, Cytosolic purine 5'-nucleotidase, GLYCEROL, ...
著者Rhimi, M, Aghajari, N.
登録日2012-09-17
公開日2012-12-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Identification and characterization of inhibitors of cytoplasmic 5'-nucleotidase cN-II issued from virtual screening.
Biochem Pharmacol, 85, 2013
4OHF
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BU of 4ohf by Molmil
Crystal structure of cytosolic nucleotidase II (LPG0095) in complex with GMP from Legionella pneumophila, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET LGR1
分子名称: Cytosolic IMP-GMP specific 5'-nucleotidase, GUANOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, ...
著者Srinivisan, B, Forouhar, F, Shukla, A, Sampangi, C, Kulkarni, S, Abashidze, M, Seetharaman, J, Lew, S, Mao, L, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.M, Tong, L, Balaram, H, Northeast Structural Genomics Consortium (NESG)
登録日2014-01-17
公開日2014-02-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Allosteric regulation and substrate activation in cytosolic nucleotidase II from Legionella pneumophila.
Febs J., 281, 2014
5CQZ
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BU of 5cqz by Molmil
Human cytosolic 5'-nucleotidase II in complex with 3-(3-Imidazol-1-ylphenyl)-N-(9H-purin-6-yl)benzamide
分子名称: 1-(biphenyl-3-yl)-1H-imidazole, Cytosolic purine 5'-nucleotidase, GLYCEROL, ...
著者Preeti, P, Aghajari, N.
登録日2015-07-22
公開日2015-12-23
最終更新日2017-09-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Identification of Noncompetitive Inhibitors of Cytosolic 5'-Nucleotidase II Using a Fragment-Based Approach.
J.Med.Chem., 58, 2015
5CR7
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BU of 5cr7 by Molmil
Human cytosolic 5'-nucleotidase II in complex with N-(9H-Purin-6-yl)-3-(3-pyrrol-1-ylphenyl)benzamide
分子名称: ACETATE ION, Cytosolic purine 5'-nucleotidase, GLYCEROL, ...
著者Aghajari, N, Preeti, P.
登録日2015-07-22
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Identification of Noncompetitive Inhibitors of Cytosolic 5'-Nucleotidase II Using a Fragment-Based Approach.
J.Med.Chem., 58, 2015
5K7Y
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BU of 5k7y by Molmil
Crystal structure of enzyme in purine metabolism
分子名称: Cytosolic purine 5'-nucleotidase, GLYCEROL
著者Skerlova, J, Hnizda, A, Pachl, P, Rezacova, P.
登録日2016-05-27
公開日2016-09-21
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Oligomeric interface modulation causes misregulation of purine 5 -nucleotidase in relapsed leukemia.
Bmc Biol., 14, 2016
5L4Z
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BU of 5l4z by Molmil
Crystal structure of enzyme in purine metabolism
分子名称: Cytosolic purine 5'-nucleotidase, GLYCEROL
著者Hnizda, A, Pachl, P, Rezacova, P.
登録日2016-05-27
公開日2016-09-21
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Oligomeric interface modulation causes misregulation of purine 5 -nucleotidase in relapsed leukemia.
Bmc Biol., 14, 2016
5L50
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BU of 5l50 by Molmil
Crystal structure of enzyme in purine metabolism
分子名称: Cytosolic purine 5'-nucleotidase, GLYCEROL
著者Hnizda, A, Pachl, P, Rezacova, P.
登録日2016-05-27
公開日2016-09-21
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.643 Å)
主引用文献Oligomeric interface modulation causes misregulation of purine 5 -nucleotidase in relapsed leukemia.
Bmc Biol., 14, 2016
5OPK
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BU of 5opk by Molmil
Crystal structure of D52N/R367Q cN-II mutant bound to dATP and free phosphate
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Cytosolic purine 5'-nucleotidase, GLYCEROL, ...
著者Hnizda, A, Pachl, P, Rezacova, P.
登録日2017-08-10
公開日2018-06-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation.
Leukemia, 32, 2018
5OPL
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BU of 5opl by Molmil
Crystal structure of K25E cN-II mutant
分子名称: Cytosolic purine 5'-nucleotidase, GLYCEROL, MAGNESIUM ION
著者Kugler, M, Hnizda, A, Pachl, P, Rezacova, P.
登録日2017-08-10
公開日2018-06-13
最終更新日2018-06-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation.
Leukemia, 32, 2018
5OPM
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BU of 5opm by Molmil
Crystal structure of D52N/R238W cN-II mutant bound to dATP and free phosphate
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Cytosolic purine 5'-nucleotidase, GLYCEROL, ...
著者Hnizda, A, Pachl, P, Rezacova, P.
登録日2017-08-10
公開日2018-06-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation.
Leukemia, 32, 2018
5OPN
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BU of 5opn by Molmil
Crystal structure of R39Q cN-II mutant
分子名称: Cytosolic purine 5'-nucleotidase, GLYCEROL
著者Hnizda, A, Pachl, P, Rezacova, P.
登録日2017-08-10
公開日2018-06-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation.
Leukemia, 32, 2018
5OPO
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BU of 5opo by Molmil
Crystal structure of R238G cN-II mutant
分子名称: Cytosolic purine 5'-nucleotidase, GLYCEROL, MAGNESIUM ION
著者Hnizda, A, Pachl, P, Rezacova, P.
登録日2017-08-10
公開日2018-06-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation.
Leukemia, 32, 2018

 

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