4RGW
 
 | | Crystal Structure of a TAF1-TAF7 Complex in Human Transcription Factor IID | | 分子名称: | GLYCEROL, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 7 | | 著者 | Wang, H, Curran, E.C, Hinds, T.R, Wang, E.H, Zheng, N. | | 登録日 | 2014-09-30 | | 公開日 | 2014-12-03 | | 最終更新日 | 2014-12-17 | | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | | 主引用文献 | Crystal structure of a TAF1-TAF7 complex in human transcription factor IID reveals a promoter binding module.
Cell Res., 24, 2014
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4OY2
 | | Crystal structure of TAF1-TAF7, a TFIID subcomplex | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 7, ... | | 著者 | Bhattacharya, S, Lou, X, Rajashankar, K, Jacobson, R.H, Webb, P. | | 登録日 | 2014-02-10 | | 公開日 | 2014-06-25 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural and functional insight into TAF1-TAF7, a subcomplex of transcription factor II D.
Proc.Natl.Acad.Sci.USA, 111, 2014
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6MZL
 | | Human TFIID canonical state | | 分子名称: | TATA-box-binding protein, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 10, ... | | 著者 | Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E. | | 登録日 | 2018-11-05 | | 公開日 | 2018-11-28 | | 最終更新日 | 2019-11-20 | | 実験手法 | ELECTRON MICROSCOPY (23 Å) | | 主引用文献 | Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
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5FUR
 | | Structure of human TFIID-IIA bound to core promoter DNA | | 分子名称: | SUPER CORE PROMOTER, TATA-BOX-BINDING PROTEIN, TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1, ... | | 著者 | Louder, R.K, He, Y, Lopez-Blanco, J.R, Fang, J, Chacon, P, Nogales, E. | | 登録日 | 2016-01-29 | | 公開日 | 2016-04-06 | | 最終更新日 | 2017-08-02 | | 実験手法 | ELECTRON MICROSCOPY (8.5 Å) | | 主引用文献 | Structure of Promoter-Bound TFIID and Model of Human Pre-Initiation Complex Assembly.
Nature, 531, 2016
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6MZM
 | | Human TFIID bound to promoter DNA and TFIIA | | 分子名称: | SCP DNA (80-MER), TATA-box-binding protein, Transcription initiation factor IIA subunit 1, ... | | 著者 | Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E. | | 登録日 | 2018-11-05 | | 公開日 | 2018-11-28 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (7.5 Å) | | 主引用文献 | Structure of human TFIID and mechanism of TBP loading onto promoter DNA.
Science, 362, 2018
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8GXQ
 | | PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state | | 分子名称: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | | 著者 | Chen, X, Wang, X, Liu, W, Ren, Y, Qu, X, Li, J, Yin, X, Xu, Y. | | 登録日 | 2022-09-21 | | 公開日 | 2022-11-02 | | 実験手法 | ELECTRON MICROSCOPY (5.04 Å) | | 主引用文献 | Structures of +1 nucleosome-bound PIC-Mediator complex.
Science, 378, 2022
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8GXS
 | | PIC-Mediator in complex with +1 nucleosome (T40N) in H-binding state | | 分子名称: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | | 著者 | Chen, X, Wang, X, Liu, W, Ren, Y, Qu, X, Li, J, Yin, X. | | 登録日 | 2022-09-21 | | 公開日 | 2022-11-02 | | 実験手法 | ELECTRON MICROSCOPY (4.16 Å) | | 主引用文献 | Structures of +1 nucleosome-bound PIC-Mediator complex.
Science, 378, 2022
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8WAK
 | | Structure of transcribing complex 2 (TC2), the initially transcribing complex with Pol II positioned 2nt downstream of TSS. | | 分子名称: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | | 著者 | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | | 登録日 | 2023-09-07 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-01-03 | | 実験手法 | ELECTRON MICROSCOPY (5.47 Å) | | 主引用文献 | Structural visualization of transcription initiation in action.
Science, 382, 2023
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8WAO
 | | Structure of transcribing complex 5 (TC5), the initially transcribing complex with Pol II positioned 5nt downstream of TSS. | | 分子名称: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | | 著者 | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | | 登録日 | 2023-09-07 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-01-03 | | 実験手法 | ELECTRON MICROSCOPY (6.4 Å) | | 主引用文献 | Structural visualization of transcription initiation in action.
Science, 382, 2023
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8WAS
 | | Structure of transcribing complex 9 (TC9), the initially transcribing complex with Pol II positioned 9nt downstream of TSS. | | 分子名称: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | | 著者 | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | | 登録日 | 2023-09-08 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-01-03 | | 実験手法 | ELECTRON MICROSCOPY (6.13 Å) | | 主引用文献 | Structural visualization of transcription initiation in action.
Science, 382, 2023
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8WAL
 | | Structure of transcribing complex 3 (TC3), the initially transcribing complex with Pol II positioned 3nt downstream of TSS. | | 分子名称: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | | 著者 | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | | 登録日 | 2023-09-07 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-01-03 | | 実験手法 | ELECTRON MICROSCOPY (8.52 Å) | | 主引用文献 | Structural visualization of transcription initiation in action.
Science, 382, 2023
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8WAN
 | | Structure of transcribing complex 4 (TC4), the initially transcribing complex with Pol II positioned 4nt downstream of TSS. | | 分子名称: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | | 著者 | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | | 登録日 | 2023-09-07 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-01-03 | | 実験手法 | ELECTRON MICROSCOPY (6.07 Å) | | 主引用文献 | Structural visualization of transcription initiation in action.
Science, 382, 2023
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8WAP
 | | Structure of transcribing complex 6 (TC6), the initially transcribing complex with Pol II positioned 6nt downstream of TSS. | | 分子名称: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | | 著者 | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | | 登録日 | 2023-09-08 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-01-03 | | 実験手法 | ELECTRON MICROSCOPY (5.85 Å) | | 主引用文献 | Structural visualization of transcription initiation in action.
Science, 382, 2023
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8WAQ
 | | Structure of transcribing complex 7 (TC7), the initially transcribing complex with Pol II positioned 7nt downstream of TSS. | | 分子名称: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | | 著者 | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | | 登録日 | 2023-09-08 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-01-03 | | 実験手法 | ELECTRON MICROSCOPY (6.29 Å) | | 主引用文献 | Structural visualization of transcription initiation in action.
Science, 382, 2023
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8WAR
 | | Structure of transcribing complex 8 (TC8), the initially transcribing complex with Pol II positioned 8nt downstream of TSS. | | 分子名称: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | | 著者 | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | | 登録日 | 2023-09-08 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-01-03 | | 実験手法 | ELECTRON MICROSCOPY (7.2 Å) | | 主引用文献 | Structural visualization of transcription initiation in action.
Science, 382, 2023
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7EGB
 | | TFIID-based holo PIC on SCP promoter | | 分子名称: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | | 著者 | Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y. | | 登録日 | 2021-03-24 | | 公開日 | 2021-05-05 | | 最終更新日 | 2023-07-26 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
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7EDX
 | | p53-bound TFIID-based core PIC on HDM2 promoter | | 分子名称: | DNA (84-mer), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | | 著者 | Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y. | | 登録日 | 2021-03-17 | | 公開日 | 2021-05-05 | | 最終更新日 | 2021-05-19 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
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7EG9
 | | TFIID-based intermediate PIC on SCP promoter | | 分子名称: | DNA (79-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | | 著者 | Chen, X, Qi, Y, Wang, X, Wu, Z, Li, J, Xu, Y. | | 登録日 | 2021-03-24 | | 公開日 | 2021-05-05 | | 最終更新日 | 2021-05-19 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
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7EG7
 | | TFIID-based core PIC on SCP promoter | | 分子名称: | DNA (79-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | | 著者 | Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y. | | 登録日 | 2021-03-24 | | 公開日 | 2021-05-05 | | 最終更新日 | 2021-05-19 | | 実験手法 | ELECTRON MICROSCOPY (6.2 Å) | | 主引用文献 | Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
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7EG8
 | | TFIID-based core PIC on PUMA promoter | | 分子名称: | DNA (85-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | | 著者 | Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y. | | 登録日 | 2021-03-24 | | 公開日 | 2021-05-05 | | 最終更新日 | 2021-05-19 | | 実験手法 | ELECTRON MICROSCOPY (7.4 Å) | | 主引用文献 | Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
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7EGA
 | | TFIID-based intermediate PIC on PUMA promoter | | 分子名称: | DNA (85-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | | 著者 | Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y. | | 登録日 | 2021-03-24 | | 公開日 | 2021-05-05 | | 最終更新日 | 2021-05-19 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
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7EGH
 | | TFIID lobe C subcomplex | | 分子名称: | DNA (45-MER), Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 2, ... | | 著者 | Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y. | | 登録日 | 2021-03-24 | | 公開日 | 2021-05-12 | | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | | 主引用文献 | Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
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7EGI
 | | TFIID in rearranged conformation | | 分子名称: | TATA-box-binding protein, Transcription initiation factor IIA subunit 1, Transcription initiation factor IIA subunit 2, ... | | 著者 | Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y. | | 登録日 | 2021-03-24 | | 公開日 | 2021-05-12 | | 実験手法 | ELECTRON MICROSCOPY (9.82 Å) | | 主引用文献 | Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
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7EGJ
 | | SCP promoter-bound TFIID-TFIIA in post TBP-loading state | | 分子名称: | DNA (74-MER), TATA-box-binding protein, Transcription initiation factor IIA subunit 1, ... | | 著者 | Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y. | | 登録日 | 2021-03-24 | | 公開日 | 2021-05-12 | | 実験手法 | ELECTRON MICROSCOPY (8.64 Å) | | 主引用文献 | Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
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7EGD
 | | SCP promoter-bound TFIID-TFIIA in initial TBP-loading state | | 分子名称: | DNA (72-MER), TATA-box-binding protein, Transcription initiation factor IIA subunit 1, ... | | 著者 | Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y. | | 登録日 | 2021-03-24 | | 公開日 | 2021-05-12 | | 実験手法 | ELECTRON MICROSCOPY (6.75 Å) | | 主引用文献 | Structural insights into preinitiation complex assembly on core promoters.
Science, 372, 2021
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