PDB: 159 件ウェブページステータス検索Chemie searchBIRD

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4WQN	Crystal structure of N6-methyladenosine RNA reader YTHDF2 分子名称: 1,2-ETHANEDIOL, GLYCEROL, YTH domain-containing family protein 2 著者 Zhu, T, Roundtree, I.A, Wang, P, Wang, X, Wang, L, Sun, C, Tian, Y, Li, J, He, C, Xu, Y. 登録日 2014-10-22 公開日 2014-11-19 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.121 Å) 主引用文献 Crystal structure of the YTH domain of YTHDF2 reveals mechanism for recognition of N6-methyladenosine. Cell Res., 24, 2014
5O8M	Crystal structure of the MmI1 YTH domain 分子名称: GLYCEROL, YTH domain-containing protein mmi1 著者 Brettschneider, J, Verdel, A, Kadlec, J. 登録日 2017-06-13 公開日 2018-04-25 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Selective termination of lncRNA transcription promotes heterochromatin silencing and cell differentiation. EMBO J., 36, 2017
2MTV	Solution Structure of the YTH Domain of YT521-B in complex with N6-Methyladenosine containing RNA 分子名称: RNA_(5'-R(*UP*GP*(6MZ)P*CP*AP*C)-3'), YTH domain-containing protein 1 著者 Theler, D, Dominguez, C, Blatter, M, Boudet, J, Allain, F.H.-T. 登録日 2014-09-01 公開日 2014-11-26 最終更新日 2014-12-31 実験手法 SOLUTION NMR 主引用文献 Solution structure of the YTH domain in complex with N6-methyladenosine RNA: a reader of methylated RNA. Nucleic Acids Res., 42, 2014
7BIK	Crystal structure of YTHDF2 in complex with m6Am 分子名称: (2~{R},3~{S},4~{R},5~{R})-2-(hydroxymethyl)-4-methoxy-5-[6-(methylamino)purin-9-yl]oxolan-3-ol, GLYCEROL, SULFATE ION, ... 著者 Wang, X, Caflisch, A. 登録日 2021-01-12 公開日 2021-11-24 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of YTHDF2 in complex with m6Am To Be Published
5ZUU	Crystal structure of AtCPSF30 YTH domain in complex with 10mer m6A-modified RNA 分子名称: 30-kDa cleavage and polyadenylation specificity factor 30, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ... 著者 Wu, B, Nie, H, Li, S, Patel, D.J. 登録日 2018-05-08 公開日 2019-05-15 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 CPSF30-L-mediated recognition of mRNA m6A modification controls alternative polyadenylation of nitrate signaling-related gene transcripts in Arabidopsis. Mol Plant, 2021
5HFZ	Mmi1 YTH domain 分子名称: YTH domain-containing protein mmi1 著者 Chatterjee, D, Goldgur, Y, Shuman, S. 登録日 2016-01-07 公開日 2016-02-10 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Transcription of lncRNA prt, clustered prt RNA sites for Mmi1 binding, and RNA polymerase II CTD phospho-sites govern the repression of pho1 gene expression under phosphate-replete conditions in fission yeast. Rna, 22, 2016
5H8A	Mmi1 YTH domain 分子名称: YTH domain-containing protein mmi1 著者 Chatterjee, D, Goldgur, Y, Shuman, S. 登録日 2015-12-23 公開日 2016-01-13 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.751 Å) 主引用文献 Transcription of lncRNA prt, clustered prt RNA sites for Mmi1 binding, and RNA polymerase II CTD phospho-sites govern the repression of pho1 gene expression under phosphate-replete conditions in fission yeast. Rna, 22, 2016
6K6U	Crystal structure of the human YTHDC2 YTH domain 分子名称: 3'-5' RNA helicase YTHDC2 著者 Ma, C, Liao, S, Xu, C. 登録日 2019-06-04 公開日 2019-12-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Crystal structure of human YTHDC2 YTH domain. Biochem.Biophys.Res.Commun., 518, 2019
2YUD	Solution structure of the YTH domain in YTH domain-containing protein 1 (Putative splicing factor YT521) 分子名称: YTH domain-containing protein 1 著者 He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Tarada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-04-06 公開日 2007-10-09 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 Solution structure of the YTH domain in YTH domain-containing protein 1 (Putative splicing factor YT521) To be Published
2YU6	Solution structure of the YTH domain in YTH domain-containing protein 2 分子名称: YTH domain-containing protein 2 著者 Endo, R, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Tarada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-04-05 公開日 2007-10-09 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 Solution structure of the YTH domain in YTH domain-containing protein 2 To be Published
7L4Y	YTH Domain of Human YTHDC1 with dsDNA Comprising Single N6mA joined by Two Six-bp DNA Duplexes in P212121 Crystal 分子名称: 1,2-ETHANEDIOL, YTH domain-containing protein 1, ssDNA 13mer 著者 Horton, J.R, Cheng, X. 登録日 2020-12-21 公開日 2021-11-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Human MettL3-MettL14 RNA adenine methyltransferase complex is active on double-stranded DNA containing lesions. Nucleic Acids Res., 49, 2021
7L4X	YTH Domain of Human YTHDC1 with dsDNA Comprising Single N6mA joined by two six-bp DNA duplexes in P3221 Crystal 分子名称: 1,2-ETHANEDIOL, YTH domain-containing protein 1, ssDNA w/N6A 著者 Horton, J.R, Cheng, X. 登録日 2020-12-21 公開日 2021-11-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Human MettL3-MettL14 RNA adenine methyltransferase complex is active on double-stranded DNA containing lesions. Nucleic Acids Res., 49, 2021
6LR2	SOLUTION STRUCTURE OF THE YTH DOMAIN IN YTH DOMAIN-2 CONTAINING PROTEIN 2 分子名称: YTH domain containing protein 2 (YTHDC2) 著者 Muto, Y, Kobayashi, N, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2020-01-15 公開日 2021-01-20 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 SOLUTION STRUCTURE OF THE YTH DOMAIN IN YTH DOMAIN-CONTAINING PROTEIN 2 TO BE PUBLISHED
8BS6	Crystal structure of YTHDF3 disulfide mutant (closed conformation) 分子名称: YTH domain-containing family protein 3 著者 Bedi, R.K, Li, Y, Caflisch, A. 登録日 2022-11-24 公開日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Crystal structure of YTHDF3 disulfide mutant (closed conformation) To Be Published
8BS5	Crystal structure of YTHDF3 YTH domain open conformation 分子名称: DI(HYDROXYETHYL)ETHER, L(+)-TARTARIC ACID, YTH domain-containing family protein 3 著者 Bedi, R.K, Caflisch, A. 登録日 2022-11-24 公開日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Crystal structure of YTHDF3 YTH domain open conformation To Be Published
8BS4	Crystal structure of YTHDF1 YTH domain dimer 分子名称: ACETATE ION, GLYCEROL, YTH domain-containing family protein 1 著者 Bedi, R.K, Caflisch, A. 登録日 2022-11-24 公開日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of YTHDF1 YTH domain dimer To Be Published
6WE8	YTH domain of human YTHDC1 分子名称: 1,2-ETHANEDIOL, GLYCEROL, SULFATE ION, ... 著者 Horton, J.R, Cheng, X. 登録日 2020-04-01 公開日 2020-07-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.18 Å) 主引用文献 Biochemical and structural basis for YTH domain of human YTHDC1 binding to methylated adenine in DNA. Nucleic Acids Res., 48, 2020
6WE9	YTH domain of human YTHDC1 with 11mer ssDNA Containing N6mA 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*CP*GP*GP*(6MA)P*CP*TP*CP*TP*G)-3'), GLYCEROL, ... 著者 Horton, J.R, Cheng, X. 登録日 2020-04-01 公開日 2020-07-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Biochemical and structural basis for YTH domain of human YTHDC1 binding to methylated adenine in DNA. Nucleic Acids Res., 48, 2020
6WEA	YTH domain of human YTHDC1 with a 10mer Oligo Containing N6mA 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*CP*GP*GP*(6MA)P*CP*TP*TP*C)-3'), SODIUM ION, ... 著者 Horton, J.R, Cheng, X. 登録日 2020-04-01 公開日 2020-07-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Biochemical and structural basis for YTH domain of human YTHDC1 binding to methylated adenine in DNA. Nucleic Acids Res., 48, 2020
6FPP	Structure of S. pombe Mmi1 分子名称: GLYCEROL, MAGNESIUM ION, YTH domain-containing protein mmi1 著者 Stowell, J.A.W, Hill, C.H, Yu, M, Wagstaff, J.L, McLaughlin, S.H, Freund, S.M.V, Passmore, L.A. 登録日 2018-02-11 公開日 2018-05-09 最終更新日 2018-06-27 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding. J. Biol. Chem., 293, 2018
6FPQ	Structure of S. pombe Mmi1 in complex with 7-mer RNA 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, RNA (5'-R(*UP*UP*AP*AP*AP*CP*C)-3'), YTH domain-containing protein mmi1 著者 Stowell, J.A.W, Hill, C.H, Yu, M, Wagstaff, J.L, McLaughlin, S.H, Freund, S.M.V, Passmore, L.A. 登録日 2018-02-11 公開日 2018-05-09 最終更新日 2018-06-27 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding. J. Biol. Chem., 293, 2018
6FPX	Structure of S. pombe Mmi1 in complex with 11-mer RNA 分子名称: GLYCEROL, RNA (5'-R(P*UP*UP*UP*AP*AP*AP*CP*CP*UP*A)-3'), YTH domain-containing protein mmi1 著者 Stowell, J.A.W, Hill, C.H, Yu, M, Wagstaff, J.L, McLaughlin, S.H, Freund, S.M.V, Passmore, L.A. 登録日 2018-02-12 公開日 2018-05-09 最終更新日 2018-06-27 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding. J. Biol. Chem., 293, 2018
5DNO	Crystal structure of Mmi1 YTH domain complex with RNA 分子名称: RNA (5'-R(*CP*UP*UP*AP*AP*AP*C)-3'), YTH domain-containing protein mmi1 著者 Wang, C.Y, Zhu, Y.W, Wu, J.H, Shi, Y.Y. 登録日 2015-09-10 公開日 2016-04-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A novel RNA-binding mode of the YTH domain reveals the mechanism for recognition of determinant of selective removal by Mmi1 Nucleic Acids Res., 44, 2016
5DNP	Crystal structure of Mmi1 YTH domain 分子名称: PHOSPHATE ION, YTH domain-containing protein mmi1 著者 Wang, C.Y, Zhu, Y.W, Shi, Y.Y, Wu, J.H. 登録日 2015-09-10 公開日 2016-04-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 A novel RNA-binding mode of the YTH domain reveals the mechanism for recognition of determinant of selective removal by Mmi1 Nucleic Acids Res., 44, 2016
5EIP	apo-structure of YTH domain of SpMmi1 分子名称: YTH domain-containing protein mmi1 著者 Wu, B.X, Xu, J.H, Su, S.C, Ma, J.B. 登録日 2015-10-30 公開日 2016-01-27 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Structural insights into the specific recognition of DSR by the YTH domain containing protein Mmi1 Biochem. Biophys. Res. Commun., 491, 2017

 

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