7AQK
 
 | | Model of the actin filament Arp2/3 complex branch junction in cells | | 分子名称: | Actin, alpha skeletal muscle, ACTA1, ... | | 著者 | Faessler, F, Dimchev, G, Hodirnau, V.V, Wan, W, Schur, F.K.M. | | 登録日 | 2020-10-22 | | 公開日 | 2020-12-02 | | 最終更新日 | 2021-01-06 | | 実験手法 | ELECTRON MICROSCOPY (9 Å) | | 主引用文献 | Cryo-electron tomography structure of Arp2/3 complex in cells reveals new insights into the branch junction.
Nat Commun, 11, 2020
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6DEC
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7JPN
 | | Cryo-EM structure of Arpin-bound Arp2/3 complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, ... | | 著者 | van Eeuwen, T, Fregoso, F.E, Dominguez, R, Zimmet, A, Boczkowska, M, Rebowski, G. | | 登録日 | 2020-08-09 | | 公開日 | 2022-02-09 | | 最終更新日 | 2022-08-24 | | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | | 主引用文献 | Molecular mechanism of Arp2/3 complex inhibition by Arpin.
Nat Commun, 13, 2022
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8P94
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1K8K
 | | Crystal Structure of Arp2/3 Complex | | 分子名称: | ACTIN-LIKE PROTEIN 2, ACTIN-LIKE PROTEIN 3, ARP2/3 COMPLEX 16 KDA SUBUNIT, ... | | 著者 | Robinson, R.C, Turbedsky, K, Kaiser, D.A, Higgs, H.N, Marchand, J.-B, Choe, S, Pollard, T.D. | | 登録日 | 2001-10-24 | | 公開日 | 2001-12-07 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structure of Arp2/3 Complex
Science, 294, 2001
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8E9B
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4JD2
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4XF2
 | | Tetragonal structure of Arp2/3 complex | | 分子名称: | Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, Actin-related protein 2/3 complex subunit 2, ... | | 著者 | Jurgenson, C.T, Pollard, T.P. | | 登録日 | 2014-12-25 | | 公開日 | 2015-11-18 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (5 Å) | | 主引用文献 | Crystals of the Arp2/3 complex in two new space groups with structural information about actin-related protein 2 and potential WASP binding sites.
Acta Crystallogr.,Sect.F, 71, 2015
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4XEI
 | | Orthorhombic isomorph of bovine Arp2/3 complex | | 分子名称: | Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, Actin-related protein 2/3 complex subunit 2, ... | | 著者 | Jurgenson, C.J, Pollard, T.P. | | 登録日 | 2014-12-23 | | 公開日 | 2015-09-02 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.874 Å) | | 主引用文献 | Crystals of the Arp2/3 complex in two new space groups with structural information about actin-related protein 2 and potential WASP binding sites.
Acta Crystallogr.,Sect.F, 71, 2015
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7TPT
 | | Single-particle Cryo-EM structure of Arp2/3 complex at branched-actin junction. | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Ding, B, Narvaez-Ortiz, H.Y, Nolen, B.J, Chowdhury, S. | | 登録日 | 2022-01-26 | | 公開日 | 2022-05-25 | | 最終更新日 | 2022-06-08 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structure of Arp2/3 complex at a branched actin filament junction resolved by single-particle cryo-electron microscopy.
Proc.Natl.Acad.Sci.USA, 119, 2022
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1TYQ
 | | Crystal structure of Arp2/3 complex with bound ATP and calcium | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related Protein 2, Actin-related protein 3, ... | | 著者 | Nolen, B.J, Littlefield, R.S, Pollard, T.D. | | 登録日 | 2004-07-08 | | 公開日 | 2004-11-09 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Crystal structures of actin-related protein 2/3 complex with bound ATP or ADP
Proc.Natl.Acad.Sci.Usa, 101, 2004
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7T5Q
 | | Cryo-EM Structure of a Transition State of Arp2/3 Complex Activation | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | 著者 | Rebowski, G, van Eeuwen, T, Boczkowska, M, Dominguez, R. | | 登録日 | 2021-12-13 | | 公開日 | 2023-06-14 | | 最終更新日 | 2023-08-02 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-EM structure of an Arp2/3 complex mini-branch capped by capping protein (CapZ)
To Be Published
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6YW6
 | | Cryo-EM structure of the ARP2/3 1B5CL isoform complex. | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ARPC1B, Actin-related protein 2, ... | | 著者 | von Loeffelholz, O, Moores, C, Purkiss, A. | | 登録日 | 2020-04-29 | | 公開日 | 2020-07-22 | | 最終更新日 | 2020-08-12 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Cryo-EM of human Arp2/3 complexes provides structural insights into actin nucleation modulation by ARPC5 isoforms.
Biol Open, 9, 2020
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6YW7
 | | Cryo-EM structure of the ARP2/3 1A5C isoform complex. | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1A, ... | | 著者 | von Loeffelholz, O, Moores, C, Purkiss, A. | | 登録日 | 2020-04-29 | | 公開日 | 2020-07-22 | | 最終更新日 | 2020-08-12 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Cryo-EM of human Arp2/3 complexes provides structural insights into actin nucleation modulation by ARPC5 isoforms.
Biol Open, 9, 2020
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1U2V
 | | Crystal structure of Arp2/3 complex with bound ADP and calcium | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin-Related Protein 2, Actin-Related Protein 3, ... | | 著者 | Nolen, B.J, Littlefield, R.S, Pollard, T.D. | | 登録日 | 2004-07-20 | | 公開日 | 2004-11-09 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Crystal structures of actin-related protein 2/3 complex with bound ATP or ADP
Proc.Natl.Acad.Sci.Usa, 101, 2004
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6UHC
 | | CryoEM structure of human Arp2/3 complex with bound NPFs | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, ... | | 著者 | Zimmet, A, van Eeuwen, T, Dominguez, R. | | 登録日 | 2019-09-27 | | 公開日 | 2020-07-01 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Cryo-EM structure of NPF-bound human Arp2/3 complex and activation mechanism.
Sci Adv, 6, 2020
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8TAH
 | | Cryo-EM structure of Cortactin-bound to Arp2/3 complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1A, ... | | 著者 | Fregoso, F.E, van Eeuwen, T, Dominguez, R. | | 登録日 | 2023-06-27 | | 公開日 | 2023-09-27 | | 最終更新日 | 2024-01-31 | | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | | 主引用文献 | Mechanism of synergistic activation of Arp2/3 complex by cortactin and WASP-family proteins.
Nat Commun, 14, 2023
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8UXW
 | | Arp2/3 branch junction complex, ADP state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | 著者 | Chavali, S.S, Chou, S.Z, Sindelar, C.V. | | 登録日 | 2023-11-11 | | 公開日 | 2024-01-31 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Cryo-EM structures reveal how phosphate release from Arp3 weakens actin filament branches formed by Arp2/3 complex.
Nat Commun, 15, 2024
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8UXX
 | | Arp2/3 branch junction complex, BeFx state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | 著者 | Chavali, S.S, Chou, S.Z, Sindelar, C.V. | | 登録日 | 2023-11-11 | | 公開日 | 2024-01-31 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cryo-EM structures reveal how phosphate release from Arp3 weakens actin filament branches formed by Arp2/3 complex.
Nat Commun, 15, 2024
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6W17
 | | Structure of Dip1-activated Arp2/3 complex with nucleated actin filament | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | 著者 | Shaaban, M, Nolen, B.J, Chowdhury, S. | | 登録日 | 2020-03-03 | | 公開日 | 2020-08-12 | | 最終更新日 | 2020-11-18 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Cryo-EM reveals the transition of Arp2/3 complex from inactive to nucleation-competent state.
Nat.Struct.Mol.Biol., 27, 2020
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6W18
 | | Structure of S. pombe Arp2/3 complex in inactive state | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1, ... | | 著者 | Shaaban, M, Nolen, B.J, Chowdhury, S. | | 登録日 | 2020-03-03 | | 公開日 | 2020-08-12 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Cryo-EM reveals the transition of Arp2/3 complex from inactive to nucleation-competent state.
Nat.Struct.Mol.Biol., 27, 2020
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3DXM
 | | Structure of Bos taurus Arp2/3 Complex with Bound Inhibitor CK0993548 | | 分子名称: | (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, ... | | 著者 | Nolen, B.J, Tomasevic, N, Russell, A, Pierce, D.W, Jia, Z, Hartman, J, Sakowicz, R, Pollard, T.D. | | 登録日 | 2008-07-24 | | 公開日 | 2009-07-28 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Characterization of two classes of small molecule inhibitors of Arp2/3 complex
Nature, 460, 2009
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3DXK
 | | Structure of Bos Taurus Arp2/3 Complex with Bound Inhibitor CK0944636 | | 分子名称: | Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, Actin-related protein 2/3 complex subunit 2, ... | | 著者 | Nolen, B.J, Tomasevic, N, Russell, A, Pierce, D.W, Jia, Z, Hartman, J, Sakowicz, R, Pollard, T.D. | | 登録日 | 2008-07-24 | | 公開日 | 2009-07-28 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Characterization of two classes of small molecule inhibitors of Arp2/3 complex
Nature, 460, 2009
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3DWL
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3RSE
 | | Structural and biochemical characterization of two binding sites for nucleation promoting factor WASp-VCA on Arp2/3 complex | | 分子名称: | Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, Actin-related protein 2/3 complex subunit 2, ... | | 著者 | Pollard, T.D, Jurgenson, C.T, Ti, S, Nolen, B.J. | | 登録日 | 2011-05-02 | | 公開日 | 2011-06-01 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Structural and biochemical characterization of two binding sites for nucleation-promoting factor WASp-VCA on Arp2/3 complex.
Proc.Natl.Acad.Sci.USA, 108, 2011
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