Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
5TT1
DownloadVisualize
BU of 5tt1 by Molmil
Crystal Structure of a Putative short-chain alcohol dehydrogenase from Burkholderia multivorans
分子名称: 1,2-ETHANEDIOL, NITRATE ION, Putative short-chain alcohol dehydrogenase, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2016-10-31
公開日2016-11-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of a Putative short-chain alcohol dehydrogenase from Burkholderia multivorans
to be published
7O4B
DownloadVisualize
BU of 7o4b by Molmil
Crystal structure of Penicillin-Binding Protein 1 (PBP1) from Staphylococcus aureus in complex with penicillin G
分子名称: CITRIC ACID, OPEN FORM - PENICILLIN G, Penicillin-binding protein 1, ...
著者Martinez Caballero, S, Hermoso, J.A.
登録日2021-04-05
公開日2021-11-03
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.593 Å)
主引用文献Integrative structural biology of the penicillin-binding protein-1 from Staphylococcus aureus , an essential component of the divisome machinery.
Comput Struct Biotechnol J, 19, 2021
1VQQ
DownloadVisualize
BU of 1vqq by Molmil
Structure of Penicillin binding protein 2a from methicillin resistant Staphylococcus aureus strain 27r at 1.80 A resolution.
分子名称: CADMIUM ION, CHLORIDE ION, penicillin-binding protein mecA, ...
著者Lim, D, Strynadka, N.C.J.
登録日2004-12-17
公開日2004-12-28
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for the beta lactam resistance of PBP2a from methicillin-resistant Staphylococcus aureus.
Nat.Struct.Biol., 9, 2002
4OVD
DownloadVisualize
BU of 4ovd by Molmil
Crystal structure of a putative peptidoglycan glycosyltransferase from Atopobium parvulum DSM 20469
分子名称: CALCIUM ION, Peptidoglycan glycosyltransferase
著者Filippova, E.V, Wawrzak, Z, Kiryukhina, O, Babnigg, G, Clancy, S, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG)
登録日2014-02-21
公開日2014-03-12
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of a putative peptidoglycan glycosyltransferase from Atopobium parvulum DSM 20469
To be Published
5KSH
DownloadVisualize
BU of 5ksh by Molmil
Crystal structure of penicillin-binding protein 2 from Neisseria gonorrhoeae containing an A501T mutation associated with cephalosporin resistance
分子名称: GLYCEROL, Penicillin-binding protein 2, SULFATE ION
著者Fedarovich, A, Davies, C.
登録日2016-07-08
公開日2017-03-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Alanine 501 Mutations in Penicillin-Binding Protein 2 from Neisseria gonorrhoeae: Structure, Mechanism, and Effects on Cephalosporin Resistance and Biological Fitness.
Biochemistry, 56, 2017
7ZG8
DownloadVisualize
BU of 7zg8 by Molmil
Crystal structure of A. baumannii penicillin-binding protein 2
分子名称: Peptidoglycan D,D-transpeptidase MrdA, ZINC ION
著者Micelli, C, Crow, A, Roper, D.I.
登録日2022-04-02
公開日2023-02-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献A conserved zinc-binding site in Acinetobacter baumannii PBP2 required for elongasome-directed bacterial cell shape.
Proc.Natl.Acad.Sci.USA, 120, 2023
2WAD
DownloadVisualize
BU of 2wad by Molmil
PENICILLIN-BINDING PROTEIN 2B (PBP-2B) FROM STREPTOCOCCUS PNEUMONIAE (STRAIN 5204)
分子名称: PENICILLIN-BINDING PROTEIN 2B, ZINC ION
著者Contreras-Martel, C, Dahout-Gonzalez, C, Dos-Santos-Martins, A, Kotnik, M, Dessen, A.
登録日2009-02-05
公開日2009-02-24
最終更新日2014-02-19
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Pbp Active Site Flexibility as the Key Mechanism for Beta-Lactam Resistance in Pneumococci
J.Mol.Biol., 387, 2009
8TJ3
DownloadVisualize
BU of 8tj3 by Molmil
Structural basis of peptidoglycan synthesis by E. coli RodA-PBP2 complex
分子名称: Peptidoglycan D,D-transpeptidase MrdA, Peptidoglycan glycosyltransferase MrdB
著者Nygaard, R, Mancia, F.
登録日2023-07-20
公開日2023-08-30
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis of peptidoglycan synthesis by E. coli RodA-PBP2 complex
Nat Commun, 14, 2023
8U55
DownloadVisualize
BU of 8u55 by Molmil
Crystal structure of Enterococcus faecium EnGen25 Penicillin-binding protein 5 (PBP5)
分子名称: Penicillin-binding protein 5
著者Pemberton, O.A, Shamoo, Y.
登録日2023-09-12
公開日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of Enterococcus faecium EnGen25 Penicillin-binding protein 5 (PBP5)
To Be Published
3EQU
DownloadVisualize
BU of 3equ by Molmil
Crystal structure of penicillin-binding protein 2 from Neisseria gonorrhoeae
分子名称: GLYCEROL, Penicillin-binding protein 2, SULFATE ION
著者Powell, A.J, Deacon, A.M, Nicholas, R.A, Davies, C.
登録日2008-10-01
公開日2008-10-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structures of Penicillin-binding Protein 2 from Penicillin-susceptible and -resistant Strains of Neisseria gonorrhoeae Reveal an Unexpectedly Subtle Mechanism for Antibiotic Resistance.
J.Biol.Chem., 284, 2009
3EQV
DownloadVisualize
BU of 3eqv by Molmil
Crystal structure of penicillin-binding protein 2 from Neisseria gonorrhoeae containing four mutations associated with penicillin resistance
分子名称: GLYCEROL, Penicillin-binding protein 2, SULFATE ION
著者Powell, A.J, Deacon, A.M, Nicholas, R.A, Davies, C.
登録日2008-10-01
公開日2008-10-21
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structures of Penicillin-binding Protein 2 from Penicillin-susceptible and -resistant Strains of Neisseria gonorrhoeae Reveal an Unexpectedly Subtle Mechanism for Antibiotic Resistance.
J.Biol.Chem., 284, 2009
6XV5
DownloadVisualize
BU of 6xv5 by Molmil
Crystal structure of penicillin-binding protein 2 from Yersinia pestis in complex with ertapenem
分子名称: L(+)-TARTARIC ACID, Peptidoglycan D,D-transpeptidase MrdA
著者Pankov, G, Hunter, W.N, Dawson, A.
登録日2020-01-21
公開日2021-02-03
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.673 Å)
主引用文献The structure of penicillin-binding protein 2 from Yersinia pestis
To Be Published
5DF7
DownloadVisualize
BU of 5df7 by Molmil
CRYSTAL STRUCTURE OF PENICILLIN-BINDING PROTEIN 3 FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH AZLOCILLIN
分子名称: (2R,4S)-5,5-dimethyl-2-[(1R)-2-oxo-1-{[(2R)-2-{[(2-oxoimidazolidin-1-yl)carbonyl]amino}-2-phenylacetyl]amino}ethyl]-1,3-thiazolidine-4-carboxylic acid, CHLORIDE ION, Cell division protein, ...
著者Ren, J, Nettleship, J.E, Males, A, Stuart, D.I, Owens, R.J.
登録日2015-08-26
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of penicillin-binding protein 3 in complexes with azlocillin and cefoperazone in both acylated and deacylated forms.
Febs Lett., 590, 2016
4WEJ
DownloadVisualize
BU of 4wej by Molmil
Crystal structure of Pseudomonas aeruginosa PBP3 with a R4 substituted allyl monocarbam
分子名称: (3R,4S,7Z)-7-(2-amino-1,3-thiazol-4-yl)-4-formyl-1-[({3-[(5R)-5-hydroxy-4-oxo-4,5-dihydropyridin-2-yl]-4-[3-(methylsulfonyl)propyl]-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl}sulfonyl)amino]-10,10-dimethyl-1,6-dioxo-3-(prop-2-en-1-yl)-9-oxa-2,5,8-triazaundec-7-en-11-oic acid, Penicillin-binding protein 3
著者Ferguson, A.D.
登録日2014-09-10
公開日2015-04-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.045 Å)
主引用文献SAR and Structural Analysis of Siderophore-Conjugated Monocarbam Inhibitors of Pseudomonas aeruginosa PBP3.
Acs Med.Chem.Lett., 6, 2015
6Y6Z
DownloadVisualize
BU of 6y6z by Molmil
Structure of Pseudomonas aeruginosa Penicillin-Binding Protein 3 (PBP3) in complex with Compound 1
分子名称: GLYCEROL, Peptidoglycan D,D-transpeptidase FtsI, ~{tert}-butyl ~{N}-[(2~{S})-2-methyl-4-oxidanyl-1-oxidanylidene-pent-4-en-2-yl]carbamate
著者Newman, H, Bellini, D, Dowson, C.G.
登録日2020-02-27
公開日2020-06-24
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Demonstration of the utility of DOS-derived fragment libraries for rapid hit derivatisation in a multidirectional fashion.
Chem Sci, 11, 2020
4YE5
DownloadVisualize
BU of 4ye5 by Molmil
The crystal structure of a peptidoglycan synthetase from Bifidobacterium adolescentis ATCC 15703
分子名称: ACETATE ION, GLYCEROL, Peptidoglycan synthetase penicillin-binding protein 3
著者Cuff, M, Tan, K, Joachimiak, G, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2015-02-23
公開日2015-03-18
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (2.052 Å)
主引用文献The crystal structure of a peptidoglycan synthetase from Bifidobacterium adolescentis ATCC 15703
To Be Published
4WEL
DownloadVisualize
BU of 4wel by Molmil
Crystal structure of Pseudomonas aeruginosa PBP3 with SMC-3176
分子名称: (3S,4S,7Z)-7-(2-amino-1,3-thiazol-4-yl)-4-formyl-1-[({3-(5-hydroxy-4-oxo-3,4-dihydropyridin-2-yl)-4-[3-(methylsulfonyl)propyl]-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl}sulfonyl)amino]-3,10,10-trimethyl-1,6-dioxo-9-oxa-2,5,8-triazaundec-7-en-11-oic acid, Penicillin-binding protein 3
著者Ferguson, A.D.
登録日2014-09-10
公開日2015-04-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献SAR and Structural Analysis of Siderophore-Conjugated Monocarbam Inhibitors of Pseudomonas aeruginosa PBP3.
Acs Med.Chem.Lett., 6, 2015
4WEK
DownloadVisualize
BU of 4wek by Molmil
Crystal structure of Pseudomonas aeruginosa PBP3 with a R4 substituted vinyl monocarbam
分子名称: (3S,4S,7Z)-7-(2-amino-1,3-thiazol-4-yl)-3-ethenyl-4-formyl-1-[({3-(5-hydroxy-4-oxo-3,4-dihydropyridin-2-yl)-4-[3-(methylsulfonyl)propyl]-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl}sulfonyl)amino]-10,10-dimethyl-1,6-dioxo-9-oxa-2,5,8-triazaundec-7-en-11-oic acid, Penicillin-binding protein 3
著者Ferguson, A.D.
登録日2014-09-10
公開日2015-04-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献SAR and Structural Analysis of Siderophore-Conjugated Monocarbam Inhibitors of Pseudomonas aeruginosa PBP3.
Acs Med.Chem.Lett., 6, 2015
5E31
DownloadVisualize
BU of 5e31 by Molmil
2.3 Angstrom Crystal Structure of the Monomeric Form of Penicillin Binding Protein 2 Prime from Enterococcus faecium.
分子名称: Penicillin binding protein 2 prime
著者Minasov, G, Wawrzak, Z, Shuvalova, L, Dubrovska, I, Flores, K, Filippova, E, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2015-10-01
公開日2015-10-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献2.3 Angstrom Crystal Structure of the Monomeric Form of Penicillin Binding Protein 2 Prime from Enterococcus faecium.
To Be Published
6Y6U
DownloadVisualize
BU of 6y6u by Molmil
Structure of Pseudomonas aeruginosa Penicillin-Binding Protein 3 (PBP3) in complex with Compound 6
分子名称: 2-(4-hydroxyphenyl)-~{N}-[(2~{S})-2-methyl-4-oxidanyl-1-oxidanylidene-pent-4-en-2-yl]ethanamide, GLYCEROL, Peptidoglycan D,D-transpeptidase FtsI
著者Newman, H, Bellini, D, Dowson, C.G.
登録日2020-02-27
公開日2020-06-24
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Demonstration of the utility of DOS-derived fragment libraries for rapid hit derivatisation in a multidirectional fashion
Chem Sci, 11, 2020
5DVY
DownloadVisualize
BU of 5dvy by Molmil
2.95 Angstrom Crystal Structure of the Dimeric Form of Penicillin Binding Protein 2 Prime from Enterococcus faecium
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Penicillin binding protein 2 prime, SULFATE ION
著者Minasov, G, Wawrzak, Z, Shuvalova, L, Dubrovska, I, Flores, K, Filippova, E, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2015-09-21
公開日2015-10-07
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献2.95 Angstrom Crystal Structure of the Dimeric Form of Penicillin Binding Protein 2 Prime from Enterococcus faecium.
To Be Published
6PL5
DownloadVisualize
BU of 6pl5 by Molmil
Structural coordination of polymerization and crosslinking by a peptidoglycan synthase complex
分子名称: Penicillin-binding protein 2/cell division protein FtsI, Peptidoglycan glycosyltransferase RodA, Unknown peptide
著者Sjodt, M, Rohs, P.D.A, Erlandson, S.C, Zheng, S, Rudner, D.Z, Bernhardt, T.G, Kruse, A.C.
登録日2019-06-30
公開日2020-03-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural coordination of polymerization and crosslinking by a SEDS-bPBP peptidoglycan synthase complex.
Nat Microbiol, 5, 2020
6PL6
DownloadVisualize
BU of 6pl6 by Molmil
Structural coordination of polymerization and crosslinking by a peptidoglycan synthase complex
分子名称: (2R,4S)-2-[(1R)-1-{[(2R)-2-amino-2-phenylacetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, Penicillin-binding protein 2/cell division protein FtsI, Peptidoglycan glycosyltransferase RodA, ...
著者Sjodt, M, Rohs, P.D.A, Erlandson, S.C, Zheng, S, Rudner, D.Z, Bernhardt, T.G, Kruse, A.C.
登録日2019-06-30
公開日2020-03-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural coordination of polymerization and crosslinking by a SEDS-bPBP peptidoglycan synthase complex.
Nat Microbiol, 5, 2020
6Q9N
DownloadVisualize
BU of 6q9n by Molmil
Crystal structure of PBP2a from MRSA in complex with piperacillin and quinazolinone
分子名称: 3-[2-[(~{E})-2-(4-ethynylphenyl)ethenyl]-4-oxidanylidene-quinazolin-3-yl]benzoic acid, CADMIUM ION, CHLORIDE ION, ...
著者Martinez-Caballero, S, Batuecas, M.T, Hermoso, J.A.
登録日2018-12-18
公開日2019-11-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The Quinazolinone Allosteric Inhibitor of PBP 2a Synergizes with Piperacillin and Tazobactam against Methicillin-Resistant Staphylococcus aureus.
Antimicrob.Agents Chemother., 63, 2019
6BSR
DownloadVisualize
BU of 6bsr by Molmil
Crystal structure of penicillin-binding protein 4 (PBP4) from Enterococcus faecalis in the benzylpenicillin bound form.
分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Moon, T.M, D'Andrea, E.D, Peti, W, Page, R.
登録日2017-12-04
公開日2018-10-31
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献The structures of penicillin-binding protein 4 (PBP4) and PBP5 fromEnterococciprovide structural insights into beta-lactam resistance.
J. Biol. Chem., 293, 2018

218500

件を2024-04-17に公開中

PDB statisticsPDBj update infoContact PDBjnumon