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1D1N
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SOLUTION STRUCTURE OF THE FMET-TRNAFMET BINDING DOMAIN OF BECILLUS STEAROTHERMOPHILLUS TRANSLATION INITIATION FACTOR IF2
分子名称: INITIATION FACTOR 2
著者Meunier, S, Spurio, S, Czisch, M, Wechselberger, R, Gueunneugues, M.
登録日1999-09-20
公開日2000-09-20
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献Structure of the fMet-tRNA(fMet)-binding domain of B. stearothermophilus initiation factor IF2.
EMBO J., 19, 2000
5OT7
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Elongation factor G-ribosome complex captures in the absence of inhibitors.
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Mace, K, Giudice, E, Chat, S, Gillet, R.
登録日2017-08-21
公開日2018-02-14
最終更新日2018-04-11
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献The structure of an elongation factor G-ribosome complex captured in the absence of inhibitors.
Nucleic Acids Res., 46, 2018
1AIP
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EF-TU EF-TS COMPLEX FROM THERMUS THERMOPHILUS
分子名称: ELONGATION FACTOR TS, ELONGATION FACTOR TU
著者Wang, Y, Jiang, Y, Meyering-Voss, M, Sprinzl, M, Sigler, P.B.
登録日1997-04-22
公開日1997-10-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of the EF-Tu.EF-Ts complex from Thermus thermophilus.
Nat.Struct.Biol., 4, 1997
1B23
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E. coli cysteinyl-tRNA and T. aquaticus elongation factor EF-TU:GTP ternary complex
分子名称: CYSTEINE, CYSTEINYL TRNA, ELONGATION FACTOR TU, ...
著者Nissen, P, Kjeldgaard, M, Thirup, S, Nyborg, J.
登録日1998-12-04
公開日1998-12-07
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The crystal structure of Cys-tRNACys-EF-Tu-GDPNP reveals general and specific features in the ternary complex and in tRNA.
Structure Fold.Des., 7, 1999
5FG3
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Crystal structure of GDP-bound aIF5B from Aeropyrum pernix
分子名称: GUANOSINE-5'-DIPHOSPHATE, Probable translation initiation factor IF-2
著者Murakami, R, Miyoshi, T, Uchiumi, T, Ito, K.
登録日2015-12-20
公開日2016-05-04
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of translation initiation factor 5B from the crenarchaeon Aeropyrum pernix.
Proteins, 84, 2016
5H7K
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Crystal structure of Elongation factor 2 GDP-form
分子名称: Elongation factor 2, GUANOSINE-5'-DIPHOSPHATE
著者Tanzawa, T, Kato, K, Uchiumi, T, Yao, M.
登録日2016-11-18
公開日2018-02-21
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.599 Å)
主引用文献The C-terminal helix of ribosomal P stalk recognizes a hydrophobic groove of elongation factor 2 in a novel fashion
Nucleic Acids Res., 46, 2018
7F66
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eIF2B-SFSV NSs-1-eIF2
分子名称: Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3, Non-structural protein NS-S, ...
著者Kashiwagi, K, Ito, T.
登録日2021-06-24
公開日2021-12-01
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献eIF2B-capturing viral protein NSs suppresses the integrated stress response.
Nat Commun, 12, 2021
7F67
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eIF2B-SFSV NSs-2-eIF2
分子名称: Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3, Non-structural protein NS-S, ...
著者Kashiwagi, K, Ito, T.
登録日2021-06-24
公開日2021-12-01
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (3.59 Å)
主引用文献eIF2B-capturing viral protein NSs suppresses the integrated stress response.
Nat Commun, 12, 2021
7SIQ
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Crystal structure of a peptide chain release factor 3 (prfC) from Stenotrophomonas maltophilia bound to GDP
分子名称: GUANOSINE-5'-DIPHOSPHATE, Peptide chain release factor 3
著者Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2021-10-14
公開日2021-10-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Crystal structure of a peptide chain release factor 3 (prfC) from Stenotrophomonas maltophilia bound to GDP
To Be Published
7ST7
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Pre translocation intermediate stalled with viomycin and bound with EF-G in a GDP and Pi state (Structure III-vio)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Carbone, C.E, Korostelev, A.A.
登録日2021-11-12
公開日2022-02-23
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP.
Nat Commun, 12, 2021
7UG7
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70S ribosome complex in an intermediate state of translocation bound to EF-G(GDP) stalled by Argyrin B
分子名称: 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ...
著者Rundlet, E.J, Wieland, M, Holm, M, Koller, T.O, Blanchard, S.C, Wilson, D.N.
登録日2022-03-24
公開日2022-05-18
実験手法ELECTRON MICROSCOPY (2.58 Å)
主引用文献The cyclic octapeptide antibiotic argyrin B inhibits translation by trapping EF-G on the ribosome during translocation.
Proc.Natl.Acad.Sci.USA, 119, 2022
7L20
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Cryo-EM structure of the human 39S mitoribosomal subunit in complex with RRFmt and EF-G2mt.
分子名称: 16S rRNA mitochondrial, 39 S P-site finger, 39S ribosomal protein L10, ...
著者Agrawal, E, Koripella, R.
登録日2020-12-15
公開日2021-05-12
最終更新日2021-12-01
実験手法ELECTRON MICROSCOPY (3.15 Å)
主引用文献Distinct mechanisms of the human mitoribosome recycling and antibiotic resistance.
Nat Commun, 12, 2021
1D8T
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CRYSTAL STRUCTURE OF ELONGATION FACTOR, TU (EF-TU-MGGDP) COMPLEXED WITH GE2270A, A THIAZOLYL PEPTIDE ANTIBIOTIC
分子名称: ACETATE ION, ELONGATION FACTOR TU, GUANOSINE-5'-DIPHOSPHATE, ...
著者Heffron, S.E, Jurnak, F.
登録日1999-10-25
公開日2000-10-25
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structure of an EF-TU Complex with a Thiazolyl Peptide Antibiotic Determined at 2.35 A Resolution: Atomic Basis for Ge2270A Inhibition of EF-TU.
Biochemistry, 39, 2000
1D2E
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CRYSTAL STRUCTURE OF MITOCHONDRIAL EF-TU IN COMPLEX WITH GDP
分子名称: ELONGATION FACTOR TU (EF-TU), GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Andersen, G.R, Thirup, S, Spremulli, L.L, Nyborg, J.
登録日1999-09-23
公開日1999-09-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献High resolution crystal structure of bovine mitochondrial EF-Tu in complex with GDP.
J.Mol.Biol., 297, 2000
1DAR
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BU of 1dar by Molmil
ELONGATION FACTOR G IN COMPLEX WITH GDP
分子名称: ELONGATION FACTOR G, GUANOSINE-5'-DIPHOSPHATE
著者Al-Karadaghi, S, Aevarsson, A, Garber, M, Zheltonosova, J, Liljas, A.
登録日1996-02-15
公開日1996-07-11
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The structure of elongation factor G in complex with GDP: conformational flexibility and nucleotide exchange.
Structure, 4, 1996
7CSL
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BU of 7csl by Molmil
Crystal structure of the archaeal EF1A-EF1B complex
分子名称: Elongation factor 1-alpha, Elongation factor 1-beta
著者Suzuki, T, Ito, K, Miyoshi, T, Murakami, R, Uchiumi, T.
登録日2020-08-15
公開日2021-06-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural insights into the Switching Off of the Interaction between the Archaeal Ribosomal Stalk and aEF1A by Nucleotide Exchange Factor aEF1B.
J.Mol.Biol., 433, 2021
7CDW
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Crystal Structure of Mycobacterium Tuberculosis Elongation Factor G1
分子名称: Elongation factor G, GUANOSINE-5'-DIPHOSPHATE
著者Gao, X, Cui, S.
登録日2020-06-20
公開日2021-09-22
最終更新日2022-02-16
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal Structure of Mycobacterium tuberculosis Elongation Factor G1.
Front Mol Biosci, 8, 2021
7D43
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eIF2B-eIF2(aP), aPg complex
分子名称: Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 2, Eukaryotic translation initiation factor 2 subunit 3, ...
著者Kashiwagi, K, Ito, T.
登録日2020-09-22
公開日2020-12-09
最終更新日2021-01-27
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献ISRIB Blunts the Integrated Stress Response by Allosterically Antagonising the Inhibitory Effect of Phosphorylated eIF2 on eIF2B.
Mol.Cell, 81, 2021
7DVQ
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Cryo-EM Structure of the Activated Human Minor Spliceosome (minor Bact Complex)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 5'-O-[(S)-hydroxy{[(R)-hydroxy{[(S)-hydroxy(methoxy)phosphoryl]oxy}phosphoryl]oxy}phosphoryl]guanosine, Armadillo repeat-containing protein 7, ...
著者Bai, R, Wan, R, Wang, L, Xu, K, Zhang, Q, Lei, J, Shi, Y.
登録日2021-01-14
公開日2021-03-31
実験手法ELECTRON MICROSCOPY (2.89 Å)
主引用文献Structure of the activated human minor spliceosome.
Science, 371, 2021
1OB2
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E. coli elongation factor EF-Tu complexed with the antibiotic kirromycin, a GTP analog, and Phe-tRNA
分子名称: ELONGATION FACTOR TU, KIRROMYCIN, MAGNESIUM ION, ...
著者Kristensen, O, Nissen, P, Nyborg, J.
登録日2003-01-24
公開日2004-05-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Kirromycin Defines a Specific Domain Arrangement of Elongation Factor EF-TU
To be Published
1OB5
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T. aquaticus elongation factor EF-Tu complexed with the antibiotic enacyloxin IIa, a GTP analog, and Phe-tRNA
分子名称: ELONGATION FACTOR TU, ENACYLOXIN IIA, MAGNESIUM ION, ...
著者Dahlberg, C, Nielsen, R.C, Parmeggiani, A, Nyborg, J, Nissen, P.
登録日2003-01-24
公開日2005-10-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Enacyloxin Iia Pinpoints a Binding Pocket of Elongation Factor TU for Development of Novel Antibiotics.
J.Biol.Chem., 281, 2006
2H5E
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Crystal structure of E.coli polypeptide release factor RF3
分子名称: GUANOSINE-5'-DIPHOSPHATE, Peptide chain release factor RF-3
著者Song, H.W, Zhou, Z.H.
登録日2006-05-26
公開日2007-05-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献RF3 induces ribosomal conformational changes responsible for dissociation of class I release factors
Cell(Cambridge,Mass.), 129, 2007
8HL1
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Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome
分子名称: 16s rRNA (1493-MER), 23s rRNA (3000-MER), 30S ribosomal protein S10, ...
著者Wang, Y.H, Zhou, J.
登録日2022-11-28
公開日2024-01-17
実験手法ELECTRON MICROSCOPY (3.93 Å)
主引用文献Cryo-electron microscopy structure and translocation mechanism of the crenarchaeal ribosome.
Nucleic Acids Res., 51, 2023
2HDN
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Trypsin-modified Elongation Factor Tu in complex with tetracycline at 2.8 Angstrom resolution
分子名称: Elongation factor EF-Tu, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Mui, S, Heffron, S.E, Aorora, A, Abel, K, Bergmann, E, Jurnak, F.
登録日2006-06-20
公開日2006-10-31
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular complementarity between tetracycline and the GTPase active site of elongation factor Tu.
Acta Crystallogr.,Sect.D, 62, 2006
2HCJ
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Trypsin-modified Elongation Factor Tu in complex with tetracycline
分子名称: GLYOXYLIC ACID, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Mui, S, Heffron, S.E, Aorora, A, Abel, K, Bergmann, E, Jurnak, F.
登録日2006-06-16
公開日2006-10-31
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Molecular complementarity between tetracycline and the GTPase active site of elongation factor Tu.
Acta Crystallogr.,Sect.D, 62, 2006

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