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7VFU
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Human N-type voltage gated calcium channel CaV2.2-alpha2/delta1-beta1 complex, bound to ziconotide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHOLESTEROL HEMISUCCINATE, ...
著者Dong, Y, Gao, Y, Wang, Y, Zhao, Y.
登録日2021-09-13
公開日2021-11-03
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Closed-state inactivation and pore-blocker modulation mechanisms of human Ca V 2.2.
Cell Rep, 37, 2021
7MIX
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BU of 7mix by Molmil
Human N-type voltage-gated calcium channel Cav2.2 in the presence of ziconotide at 3.0 Angstrom resolution
分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Yan, N, Gao, S, Yao, X.
登録日2021-04-18
公開日2021-07-07
最終更新日2021-08-18
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure of human Ca v 2.2 channel blocked by the painkiller ziconotide.
Nature, 596, 2021
1MVI
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N-TYPE CALCIUM CHANNEL BLOCKER, OMEGA-CONOTOXIN MVIIA, NMR, 15 STRUCTURES
分子名称: MVIIA
著者Nielsen, K.J, Thomas, L, Lewis, R.J, Alewood, P.F, Craik, D.J.
登録日1996-08-02
公開日1997-08-12
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献A consensus structure for omega-conotoxins with different selectivities for voltage-sensitive calcium channel subtypes: comparison of MVIIA, SVIB and SNX-202.
J.Mol.Biol., 263, 1996
1MVJ
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N-TYPE CALCIUM CHANNEL BLOCKER, OMEGA-CONOTOXIN MVIIA NMR, 15 STRUCTURES
分子名称: SVIB
著者Nielsen, K.J, Thomas, L, Lewis, R.J, Alewood, P.F, Craik, D.J.
登録日1996-08-02
公開日1997-08-12
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献A consensus structure for omega-conotoxins with different selectivities for voltage-sensitive calcium channel subtypes: comparison of MVIIA, SVIB and SNX-202.
J.Mol.Biol., 263, 1996
1AV3
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POTASSIUM CHANNEL BLOCKER KAPPA CONOTOXIN PVIIA FROM C. PURPURASCENS, NMR, 20 STRUCTURES
分子名称: Kappa-conotoxin PVIIA
著者Scanlon, M.J, Naranjo, D, Thomas, L, Alewood, P.F, Lewis, R.J, Craik, D.J.
登録日1997-09-24
公開日1998-10-14
最終更新日2020-12-16
実験手法SOLUTION NMR
主引用文献Solution structure and proposed binding mechanism of a novel potassium channel toxin kappa-conotoxin PVIIA.
Structure, 5, 1997
6CEG
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Solution NMR structure of the omega conotoxin MoVIB from Conus moncuri
分子名称: conotoxin MoVIB
著者Rosengren, K.J.
登録日2018-02-11
公開日2018-03-07
最終更新日2020-01-01
実験手法SOLUTION NMR
主引用文献Novel analgesic omega-conotoxins from the vermivorous cone snail Conus moncuri provide new insights into the evolution of conopeptides.
Sci Rep, 8, 2018
2N8H
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Structural basis for the inhibition of voltage-gated sodium channels with conotoxin-muOxi-GVIIJ
分子名称: conotoxin-muOxi-GVIIJ
著者Green, B.R, Chhabra, S, Norton, R.S.
登録日2015-10-15
公開日2016-02-03
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural Basis for the Inhibition of Voltage-gated Sodium Channels by Conotoxin mu O-GVIIJ.
J.Biol.Chem., 291, 2016
1DW4
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NMR STRUCTURE OF OMEGA-CONOTOXIN MVIIA: CONSTRAINTS ON DISULPHIDE BRIDGES
分子名称: OMEGA-CONOTOXIN MVIIA
著者Atkinson, R.A, Kieffer, B, Dejaegere, A, Sirockin, F, Lefevre, J.-F.
登録日2000-01-24
公開日2000-03-01
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献Structural and dynamic characterization of omega-conotoxin MVIIA: the binding loop exhibits slow conformational exchange.
Biochemistry, 39, 2000
1TTL
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Omega-conotoxin GVIA, a N-type calcium channel blocker
分子名称: Omega-conotoxin GVIA
著者Mould, J, Yasuda, T, Schroeder, C.I, Beedle, A.M, Doering, C.J, Zamponi, G.W, Adams, D.J, Lewis, R.J.
登録日2004-06-23
公開日2004-07-13
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献The alpha2delta auxiliary subunit reduces affinity of omega-conotoxins for recombinant N-type (Cav2.2) calcium channels
J.Biol.Chem., 279, 2004
1TTK
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NMR solution structure of omega-conotoxin MVIIA, a N-type calcium channel blocker
分子名称: Omega-conotoxin MVIIa
著者Adams, D.J, Smith, A.B, Schroeder, C.I, Yasuda, T, Lewis, R.J.
登録日2004-06-22
公開日2004-07-06
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献omega-conotoxin CVID inhibits a pharmacologically distinct voltage-sensitive calcium channel associated with transmitter release from preganglionic nerve terminals
J.Biol.Chem., 278, 2003
2N8E
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Three-dimensional structure of cyclic PVIIA
分子名称: Kappa-conotoxin PVIIA
著者Kwon, S, Schroeder, C, Craik, D.
登録日2015-10-13
公開日2016-08-24
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Efficient enzymatic cyclization of an inhibitory cystine knot-containing peptide.
Biotechnol.Bioeng., 113, 2016
1AS5
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SOLUTION STRUCTURE OF CONOTOXIN Y-PIIIE FROM CONUS PURPURASCENS, NMR, 14 STRUCTURES
分子名称: CONOTOXIN Y-PIIIE
著者Mitchell, S.S, Shon, K, Foster, M.P, Olivera, B.M, Ireland, C.M.
登録日1997-08-13
公開日1998-10-14
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献Three-dimensional solution structure of conotoxin psi-PIIIE, an acetylcholine gated ion channel antagonist.
Biochemistry, 37, 1998
1DW5
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NMR STRUCTURE OF OMEGA-CONOTOXIN MVIIA: NO CONSTRAINTS ON DISULPHIDE BRIDGES
分子名称: OMEGA-CONOTOXIN MVIIA
著者Atkinson, R.A, Kieffer, B, Dejaegere, A, Sirockin, F, Lefevre, J.-F.
登録日2000-01-24
公開日2000-03-01
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献Structural and dynamic characterization of omega-conotoxin MVIIA: the binding loop exhibits slow conformational exchange.
Biochemistry, 39, 2000
1TT3
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NMR soulution structure of omega-conotoxin [K10]MVIIA
分子名称: Omega-conotoxin MVIIa
著者Adams, D.J, Smith, A.B, Schroeder, C.I, Yasuda, T, Lewis, R.J.
登録日2004-06-21
公開日2004-07-06
最終更新日2021-11-10
実験手法SOLUTION NMR
主引用文献omega-conotoxin CVID inhibits a pharmacologically distinct voltage-sensitive calcium channel associated with transmitter release from preganglionic nerve terminals
J.Biol.Chem., 278, 2003
1TR6
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BU of 1tr6 by Molmil
NMR solution structure of omega-conotoxin [K10]GVIA, a cyclic cysteine knot peptide
分子名称: Omega-conotoxin GVIA
著者Mould, J, Yasuda, T, Schroeder, C.I, Beedle, A.M, Doering, C.J, Zamponi, G.W, Adams, D.J, Lewis, R.J.
登録日2004-06-21
公開日2004-07-13
最終更新日2011-10-05
実験手法SOLUTION NMR
主引用文献The alpha2delta auxiliary subunit reduces affinity of omega-conotoxins for recombinant N-type (Cav2.2) calcium channels
J.Biol.Chem., 279, 2004
1OMC
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BU of 1omc by Molmil
SOLUTION STRUCTURE OF OMEGA-CONOTOXIN GVIA USING 2-D NMR SPECTROSCOPY AND RELAXATION MATRIX ANALYSIS
分子名称: OMEGA-CONOTOXIN GVIA
著者Davis, J.H, Bradley, E.K, Miljanich, G.P, Nadasdi, L, Ramachandran, J, Basus, V.J.
登録日1993-04-28
公開日1994-01-31
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Solution structure of omega-conotoxin GVIA using 2-D NMR spectroscopy and relaxation matrix analysis.
Biochemistry, 32, 1993
1OMG
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NMR STUDY OF OMEGA-CONOTOXIN MVIIA
分子名称: OMEGA-CONOTOXIN MVIIA
著者Kohno, T, Kim, J.-I, Kobayashi, K, Kodera, Y, Maeda, T, Sato, K.
登録日1995-04-26
公開日1996-04-03
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Three-dimensional structure in solution of the calcium channel blocker omega-conotoxin MVIIA.
Biochemistry, 34, 1995
1JLO
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Solution Structure of the Noncompetitive Skeletal Muscle Nicotinic Acetylcholine Receptor Antagonist Psi-conotoxin PIIIE
分子名称: PSI-CONOTOXIN PIIIE
著者Van Wagoner, R.M, Ireland, C.M.
登録日2001-07-16
公開日2003-06-24
最終更新日2011-08-24
実験手法SOLUTION NMR
主引用文献An Improved Solution Structure for psi-Conotoxin Piiie
Biochemistry, 42, 2003
1F3K
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THREE-DIMENSIONAL SOLUTION STRUCTURE OF OMEGA-CONOTOXIN TXVII, AN L-TYPE CALCIUM CHANNEL BLOCKER
分子名称: OMEGA-CONOTOXIN TXVII
著者Kobayashi, K, Sasaki, T, Sato, K, Kohno, T.
登録日2000-06-05
公開日2000-12-13
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献Three-dimensional solution structure of omega-conotoxin TxVII, an L-type calcium channel blocker.
Biochemistry, 39, 2000
1KCP
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3D STRUCTURE OF K-CONOTOXIN PVIIA, A NOVEL POTASSIUM CHANNEL-BLOCKING TOXIN FROM CONE SNAILS, NMR, 22 STRUCTURES
分子名称: KAPPA-CONOTOXIN PVIIA
著者Savarin, P, Guenneugues, M, Gilquin, B, Lamthanh, H, Gasparini, S, Zinn-Justin, S, Menez, A.
登録日1998-01-27
公開日1998-10-14
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Three-dimensional structure of kappa-conotoxin PVIIA, a novel potassium channel-blocking toxin from cone snails.
Biochemistry, 37, 1998
1FEO
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BU of 1feo by Molmil
Solution structure of omega-conotoxin MVIIA with C-terminal Gly
分子名称: OMEGA-CONOTOXIN MVIIA-GLY
著者Goldenberg, D.P, Koehn, R.E, Gilbert, D.E, Wagner, G.
登録日2000-07-21
公開日2000-08-23
最終更新日2021-11-03
実験手法SOLUTION NMR
主引用文献Solution structure and backbone dynamics of an omega-conotoxin precursor
Protein Sci., 10, 2001
1FYG
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Solution structure of omega conotoxin SO3 determined by 1H-NMR
分子名称: OMEGA CONOTOXIN SO3
著者Yan, Y, Zhang, R.
登録日2000-09-29
公開日2000-10-18
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Three-dimensional solution structure of w-conotoxin SO3 determined by 1H NMR
Chin.Sci.Bull., 48, 2003
1FU3
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THREE-DIMENSIONAL STRUCTURE IN SOLUTION OF THE SODIUM CHANNEL AGONIST/ANTAGONIST DELTA-CONOTOXIN TXVIA
分子名称: DELTA-CONOTOXIN TXVIA
著者Kohno, T, Sasaki, T, Fainzilber, M, Sato, K.
登録日2000-09-14
公開日2002-09-20
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Three-dimensional solution structure of the sodium channel agonist/antagonist delta-conotoxin TxVIA.
J.Biol.Chem., 277, 2002
2CCO
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BU of 2cco by Molmil
STRUCTURE OF THE CALCIUM CHANNEL BLOCKER OMEGA CONOTOXIN GVIA, NMR, 20 STRUCTURES
分子名称: OMEGA-CONOTOXIN GVIA
著者Pallaghy, P.K, Norton, R.S.
登録日1998-02-13
公開日1998-07-15
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Refined solution structure of omega-conotoxin GVIA: implications for calcium channel binding
J.Pept.Res., 53, 1999
1RMK
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Solution structure of conotoxin MrVIB
分子名称: Mu-O-conotoxin MrVIB
著者Daly, N.L, Ekberg, J.A, Thomas, L, Adams, D.J, Lewis, R.J, Craik, D.J.
登録日2003-11-28
公開日2004-09-07
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Structures of muO-conotoxins from Conus marmoreus. Inhibitors of tetrodotoxin (TTX)-sensitive and TTX-resistant sodium channels in mammalian sensory neurons
J.Biol.Chem., 279, 2004

 

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