7URG
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6DQX
| Actinobacillus ureae class Id ribonucleotide reductase alpha subunit | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... | 著者 | McBride, M.J, Palowitch, G.M, Boal, A.K. | 登録日 | 2018-06-11 | 公開日 | 2019-04-17 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Structures of Class Id Ribonucleotide Reductase Catalytic Subunits Reveal a Minimal Architecture for Deoxynucleotide Biosynthesis. Biochemistry, 58, 2019
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6DQW
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7B9Q
| The SERp optimized structure of Ribonucleotide reductase from Rhodobacter sphaeroides | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, Vitamin B12-dependent ribonucleotide reductase | 著者 | Loderer, C, Feiler, C, Wilk, P, Kabinger, F. | 登録日 | 2020-12-14 | 公開日 | 2022-01-12 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | 主引用文献 | HUG Domain Is Responsible for Active Dimer Stabilization in an NrdJd Ribonucleotide Reductase. Biochemistry, 61, 2022
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7B9P
| Structure of Ribonucleotide reductase from Rhodobacter sphaeroides | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, Vitamin B12-dependent ribonucleotide reductase | 著者 | Wilk, P, Feiler, C, Loderer, C, Kabinger, F. | 登録日 | 2020-12-14 | 公開日 | 2022-01-12 | 最終更新日 | 2022-08-10 | 実験手法 | X-RAY DIFFRACTION (2.646 Å) | 主引用文献 | HUG Domain Is Responsible for Active Dimer Stabilization in an NrdJd Ribonucleotide Reductase. Biochemistry, 61, 2022
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6MW3
| EM structure of Bacillus subtilis ribonucleotide reductase inhibited filament composed of NrdE alpha subunit and NrdF beta subunit with dATP | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Ribonucleoside-diphosphate reductase, Ribonucleoside-diphosphate reductase NrdF beta subunit | 著者 | Thomas, W.C, Bacik, J.P, Kaelber, J.T, Ando, N. | 登録日 | 2018-10-29 | 公開日 | 2019-06-19 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.65 Å) | 主引用文献 | Convergent allostery in ribonucleotide reductase. Nat Commun, 10, 2019
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4ERM
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4X3V
| Crystal structure of human ribonucleotide reductase 1 bound to inhibitor | 分子名称: | N~6~-{N-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetyl]-2-methyl-D-alanyl}-D-lysine, Ribonucleoside-diphosphate reductase large subunit, THYMIDINE-5'-TRIPHOSPHATE | 著者 | Dealwis, C.G, Ahmad, M.F, Alam, I. | 登録日 | 2014-12-01 | 公開日 | 2015-11-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Identification of Non-nucleoside Human Ribonucleotide Reductase Modulators. J.Med.Chem., 58, 2015
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6R1R
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7MDI
| Structure of the Neisseria gonorrhoeae ribonucleotide reductase in the inactive state | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Levitz, T.S, Drennan, C.L, Brignole, E.J. | 登録日 | 2021-04-05 | 公開日 | 2022-01-05 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Effects of chameleon dispense-to-plunge speed on particle concentration, complex formation, and final resolution: A case study using the Neisseria gonorrhoeae ribonucleotide reductase inactive complex. J.Struct.Biol., 214, 2021
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4R1R
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6W4X
| Holocomplex of E. coli class Ia ribonucleotide reductase with GDP and TTP | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MU-OXO-DIIRON, ... | 著者 | Kang, G, Taguchi, A, Stubbe, J, Drennan, C. | 登録日 | 2020-03-11 | 公開日 | 2020-04-08 | 最終更新日 | 2020-05-06 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structure of a trapped radical transfer pathway within a ribonucleotide reductase holocomplex. Science, 368, 2020
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5TUS
| Potent competitive inhibition of human ribonucleotide reductase by a novel non-nucleoside small molecule | 分子名称: | 2-hydroxy-N'-[(Z)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide, MAGNESIUM ION, Ribonucleoside-diphosphate reductase large subunit, ... | 著者 | Mohammed, F.A, Alam, I, Dealwis, C.G. | 登録日 | 2016-11-07 | 公開日 | 2017-08-02 | 最終更新日 | 2020-01-01 | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | 主引用文献 | Potent competitive inhibition of human ribonucleotide reductase by a nonnucleoside small molecule. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5IM3
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5R1R
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4ERP
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2R1R
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7R1R
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7RW6
| BORF2-APOBEC3Bctd Complex | 分子名称: | DNA dC->dU-editing enzyme APOBEC-3B, Maltose/maltodextrin-binding periplasmic protein,Ribonucleoside-diphosphate reductase large subunit, ZINC ION | 著者 | Shaban, N.M, Yan, R, Shi, K, McLellan, J.S, Yu, Z, Harris, R.S. | 登録日 | 2021-08-19 | 公開日 | 2022-04-27 | 最終更新日 | 2022-05-04 | 実験手法 | ELECTRON MICROSCOPY (2.55 Å) | 主引用文献 | Cryo-EM structure of the EBV ribonucleotide reductase BORF2 and mechanism of APOBEC3B inhibition. Sci Adv, 8, 2022
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6CGN
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7AGJ
| Ribonucleotide Reductase R1 protein from Aquifex aeolicus | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Rehling, D, Scaletti, E.R, Stenmark, P. | 登録日 | 2020-09-22 | 公開日 | 2021-10-06 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural and Biochemical Investigation of Class I Ribonucleotide Reductase from the Hyperthermophile Aquifex aeolicus. Biochemistry, 61, 2022
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6AUI
| Human ribonucleotide reductase large subunit (alpha) with dATP and CDP | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Brignole, E.J, Drennan, C.L, Asturias, F.J, Tsai, K.L, Penczek, P.A. | 登録日 | 2017-09-01 | 公開日 | 2018-04-18 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | 3.3- angstrom resolution cryo-EM structure of human ribonucleotide reductase with substrate and allosteric regulators bound. Elife, 7, 2018
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6CGM
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6CGL
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5CNV
| Crystal structure of the dATP inhibited E. coli class Ia ribonucleotide reductase complex bound to GDP and TTP at 3.20 Angstroms resolution | 分子名称: | 2'-DEOXYADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Chen, P.Y.-T, Zimanyi, C.M, Funk, M.A, Drennan, C.L. | 登録日 | 2015-07-18 | 公開日 | 2016-01-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Molecular basis for allosteric specificity regulation in class Ia ribonucleotide reductase from Escherichia coli. Elife, 5, 2016
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