7F27
| Crystal structure of polyketide ketosynthase | 分子名称: | 3-oxoacyl-(Acyl-carrier-protein) synthase | 著者 | Kim, Y, Lee, W.C. | 登録日 | 2021-06-10 | 公開日 | 2022-06-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.806 Å) | 主引用文献 | Structural basis of the complementary activity of two ketosynthases in aryl polyene biosynthesis. Sci Rep, 11, 2021
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1DD8
| CRYSTAL STRUCTURE OF BETA-KETOACYL-[ACYL CARRIER PROTEIN] SYNTHASE I FROM ESCHERICHIA COLI | 分子名称: | BETA-KETOACYL [ACYL CARRIER PROTEIN] SYNTHASE I | 著者 | Olsen, J.G, Kadziola, A, von Wettstein-Knowles, P, Siggaard-Andersen, M, Lindquist, Y, Larsen, S. | 登録日 | 1999-11-09 | 公開日 | 1999-11-18 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The X-ray crystal structure of beta-ketoacyl [acyl carrier protein] synthase I. FEBS Lett., 460, 1999
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1B3N
| BETA-KETOACYL CARRIER PROTEIN SYNTHASE AS A DRUG TARGET, IMPLICATIONS FROM THE CRYSTAL STRUCTURE OF A COMPLEX WITH THE INHIBITOR CERULENIN. | 分子名称: | (2S, 3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE, PROTEIN (KETOACYL ACYL CARRIER PROTEIN SYNTHASE 2) | 著者 | Moche, M, Schneider, G, Edwards, P, Dehesh, K, Lindqvist, Y. | 登録日 | 1998-12-14 | 公開日 | 1999-04-06 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Structure of the complex between the antibiotic cerulenin and its target, beta-ketoacyl-acyl carrier protein synthase. J.Biol.Chem., 274, 1999
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1W0I
| Arabidopsis thaliana Mitochondrial KAS | 分子名称: | 3-OXOACYL CARRIER PROTEIN SYNTHASE, POTASSIUM ION, SULFATE ION | 著者 | Olsen, J.G, Rasmussen, A.V, von Wettstein-Knowles, P, Henriksen, A. | 登録日 | 2004-06-04 | 公開日 | 2004-11-10 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of the mitochondrial beta-ketoacyl-[acyl carrier protein] synthase from Arabidopsis and its role in fatty acid synthesis. FEBS Lett., 577, 2004
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5KOF
| Crosslinked Crystal Structure of Type II Fatty Acid Synthase Ketosynthase, FabB, and Acyl Carrier Protein, AcpP | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] synthase 1, Acyl carrier protein, [(3~{S})-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-4-[[3-oxidanylidene-3-[2-(prop-2-enoylamino)ethylamino]propyl]amino]butyl] dihydrogen phosphate | 著者 | Milligan, J.C, Jackson, D.R, Barajas, J.F, Tsai, S.C. | 登録日 | 2016-06-30 | 公開日 | 2018-01-24 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Molecular basis for interactions between an acyl carrier protein and a ketosynthase. Nat.Chem.Biol., 15, 2019
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6C9U
| Crystal structure of [KS3][AT3] didomain from module 3 of 6-deoxyerthronolide B synthase in complex with antibody fragment (Fab) | 分子名称: | 6-deoxyerythronolide-B synthase EryA2, modules 3 and 4, Heavy chain of Fab 1B2, ... | 著者 | Deis, L.N, Li, X, Mathews, I.I, Khosla, C. | 登録日 | 2018-01-28 | 公開日 | 2018-05-23 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Structure-Function Analysis of the Extended Conformation of a Polyketide Synthase Module. J. Am. Chem. Soc., 140, 2018
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4R8E
| Crystal structure of beta-ketoacyl-ACP synthase II (FabF) from Yersinia pestis | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 著者 | Himiari, Z, Nanson, J.D, Swarbrick, C.M.D, Forwood, J.K. | 登録日 | 2014-09-02 | 公開日 | 2014-12-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural Characterisation of the Beta-Ketoacyl-Acyl Carrier Protein Synthases, FabF and FabH, of Yersinia pestis. Sci Rep, 5, 2015
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4V8L
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1J3N
| Crystal Structure of 3-oxoacyl-(acyl-carrier protein) Synthase II from Thermus thermophilus HB8 | 分子名称: | 3-oxoacyl-(acyl-carrier protein) synthase II, CITRIC ACID, MAGNESIUM ION | 著者 | Bagautdinov, B, Miyano, M, Tahirov, T.H, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2003-02-10 | 公開日 | 2003-03-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of 3-oxoacyl-(acyl-carrier protein) synthase II from Thermus thermophilus HB8. Acta Crystallogr.,Sect.F, 64, 2008
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6Y2I
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3O04
| Crystal structure of the beta-keto-acyl carrier protein synthase II (lmo2201) from Listeria monocytogenes | 分子名称: | beta-keto-acyl carrier protein synthase II | 著者 | Anderson, S.M, Wawrzak, Z, Onopriyenko, O, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2010-07-19 | 公開日 | 2010-08-04 | 最終更新日 | 2021-10-06 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal structure of the beta-keto-acyl carrier protein synthase II (lmo2201) from Listeria monocytogenes To be Published
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4WKY
| Streptomcyes albus JA3453 oxazolomycin ketosynthase domain OzmN KS2 | 分子名称: | 1,2-ETHANEDIOL, Beta-ketoacyl synthase, GLYCEROL, ... | 著者 | Cuff, M.E, Mack, J.C, Endres, M, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2014-10-03 | 公開日 | 2014-10-29 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases. Proc.Natl.Acad.Sci.USA, 112, 2015
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6Y2J
| Crystal structure of M. tuberculosis KasA in complex with 4,4,4-trifluoro-N-(isoquinolin-6-yl)butane-1-sulfonamide | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] synthase 1, 4,4,4-tris(fluoranyl)-~{N}-isoquinolin-6-yl-butane-1-sulfonamide, SODIUM ION, ... | 著者 | Chung, C. | 登録日 | 2020-02-16 | 公開日 | 2020-04-08 | 最終更新日 | 2020-05-20 | 実験手法 | X-RAY DIFFRACTION (2.886 Å) | 主引用文献 | Exploring the SAR of the beta-Ketoacyl-ACP Synthase Inhibitor GSK3011724A and Optimization around a Genotoxic Metabolite. Acs Infect Dis., 6, 2020
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4TKT
| Streptomyces platensis isomigrastatin ketosynthase domain MgsF KS6 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, AT-less polyketide synthase, CHLORIDE ION, ... | 著者 | Chang, C, Li, H, Endres, M, Bingman, C.A, Yennamalli, R, Lohman, J.R, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | 登録日 | 2014-05-27 | 公開日 | 2014-06-11 | 最終更新日 | 2023-03-22 | 実験手法 | X-RAY DIFFRACTION (2.4289 Å) | 主引用文献 | Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases. Proc.Natl.Acad.Sci.USA, 112, 2015
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7PPS
| apo FabB from Pseudomonas aeruginosa with single point mutation C161A | 分子名称: | 1,2-ETHANEDIOL, 3-oxoacyl-[acyl-carrier-protein] synthase 1, CHLORIDE ION, ... | 著者 | Georgiou, C, Brenk, R, Yadrykhinsky, V. | 登録日 | 2021-09-15 | 公開日 | 2021-10-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Crystal structure of Pseudomonas aeruginosa FabB C161A, a template for structure-based design for new antibiotics. F1000Res, 10, 2021
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3U0F
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6FIJ
| Structure of the loading/condensing region (SAT-KS-MAT) of the cercosporin fungal non-reducing polyketide synthase (NR-PKS) CTB1 | 分子名称: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLYCEROL, ... | 著者 | Herbst, D.A, Jakob, R.P, Townsend, C.A, Maier, T. | 登録日 | 2018-01-18 | 公開日 | 2018-03-21 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | 主引用文献 | The structural organization of substrate loading in iterative polyketide synthases. Nat. Chem. Biol., 14, 2018
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7Q5S
| Protein community member fatty acid synthase complex from C. thermophilum | 分子名称: | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase, 3-oxoacyl-[acyl-carrier-protein] reductase | 著者 | Chojnowski, G, Skalidis, I, Kyrilis, F.L, Tueting, C, Hamdi, F, Kastritis, P.L. | 登録日 | 2021-11-04 | 公開日 | 2022-02-02 | 最終更新日 | 2023-12-13 | 実験手法 | ELECTRON MICROSCOPY (4.47 Å) | 主引用文献 | Cryo-EM and artificial intelligence visualize endogenous protein community members. Structure, 30, 2022
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3U0E
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6FIK
| ACP2 crosslinked to the KS of the loading/condensing region of the CTB1 PKS | 分子名称: | Polyketide synthase | 著者 | Herbst, D.A, Huitt-Roehl, C.R, Jakob, R.P, Townsend, C.A, Maier, T. | 登録日 | 2018-01-18 | 公開日 | 2018-03-21 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (7.1 Å) | 主引用文献 | The structural organization of substrate loading in iterative polyketide synthases. Nat. Chem. Biol., 14, 2018
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3OYT
| 1.84 Angstrom resolution crystal structure of 3-oxoacyl-(acyl carrier protein) synthase I (fabB) from Yersinia pestis CO92 | 分子名称: | 1,2-ETHANEDIOL, 3-oxoacyl-[acyl-carrier-protein] synthase I, DI(HYDROXYETHYL)ETHER, ... | 著者 | Halavaty, A.S, Wawrzak, Z, Onopriyenko, O, Peterson, S, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2010-09-23 | 公開日 | 2011-01-12 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | 1.84 Angstrom resolution crystal structure of 3-oxoacyl-(acyl carrier protein) synthase I (fabB) from Yersinia pestis CO92 To be Published
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1KAS
| BETA-KETOACYL-ACP SYNTHASE II FROM ESCHERICHIA COLI | 分子名称: | BETA-KETOACYL ACP SYNTHASE II | 著者 | Huang, W, Jia, J, Edwards, P, Dehesh, K, Schneider, G, Lindqvist, Y. | 登録日 | 1997-12-22 | 公開日 | 1999-03-02 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of beta-ketoacyl-acyl carrier protein synthase II from E.coli reveals the molecular architecture of condensing enzymes. EMBO J., 17, 1998
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5LD8
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1OXH
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8EE0
| KS-AT didomain from module 2 of the 6-deoxyerythronolide B synthase in complex with antibody fragment 1B2 | 分子名称: | 1B2 antibody heavy chain, 1B2 antibody light chain, 6-deoxyerythronolide B synthase | 著者 | Cogan, D.P, Brodsky, K.L, Guzman, K.M, Mathews, I.I, Khosla, C. | 登録日 | 2022-09-06 | 公開日 | 2023-05-31 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Discovery and Characterization of Antibody Probes of Module 2 of the 6-Deoxyerythronolide B Synthase. Biochemistry, 62, 2023
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