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8G0G
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Crystal structure of diphtheria toxin H223Q/H257Q double mutant (pH 4.5)
分子名称: ADENYLYL-3'-5'-PHOSPHO-URIDINE-3'-MONOPHOSPHATE, Diphtheria toxin
著者Lovell, S, Kashipathy, M.M, Battaile, K.P, Ladokhin, A.S.
登録日2023-01-31
公開日2023-07-05
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Histidine Protonation and Conformational Switching in Diphtheria Toxin Translocation Domain.
Toxins, 15, 2023
8G0F
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Crystal structure of diphtheria toxin H223Q/H257Q double mutant (pH 5.5)
分子名称: Diphtheria toxin
著者Lovell, S, Kashipathy, M.M, Battaile, K.P, Ladokhin, A.S.
登録日2023-01-31
公開日2023-07-05
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Histidine Protonation and Conformational Switching in Diphtheria Toxin Translocation Domain.
Toxins, 15, 2023
7RRW
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Monomeric CRM197 expressed in E. coli
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Diphtheria toxin
著者Gallagher, D.T, Lees, A.
登録日2021-08-10
公開日2022-11-09
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Monomeric crystal structure of the vaccine carrier protein CRM 197 and implications for vaccine development.
Acta Crystallogr.,Sect.F, 79, 2023
7RB4
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Crystal structure of Peptono Toxin, a diphtheria toxin homolog, from Seinonella peptonophila
分子名称: Diphtheria toxin, C domain, IODIDE ION
著者Sugiman-Marangos, S.N, Gill, S.K, Melnyk, R.A.
登録日2021-07-05
公開日2022-04-20
最終更新日2022-11-02
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Structures of distant diphtheria toxin homologs reveal functional determinants of an evolutionarily conserved toxin scaffold.
Commun Biol, 5, 2022
7O4W
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Crystal structure of diphtheria toxin mutant CRM197 with a disulphide bond replaced by a Cys-Acetone-Cys bridge
分子名称: 1,2-ETHANEDIOL, 1-hydroxypropan-2-one, ACETATE ION, ...
著者Veggi, D, Dello Iacono, L.
登録日2021-04-07
公開日2022-04-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.03002071 Å)
主引用文献Retaining the structural integrity of disulfide bonds in diphtheria toxoid carrier protein is crucial for the effectiveness of glycoconjugate vaccine candidates.
Chem Sci, 13, 2022
7K7E
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Crystal structure of diphtheria toxin from crystals obtained at pH 7.0
分子名称: Diphtheria toxin
著者Lovell, S, Kashipathy, M.M, Battaile, K.P, Rodnin, M.V, Ladokhin, A.S.
登録日2020-09-22
公開日2020-11-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the Diphtheria Toxin at Acidic pH: Implications for the Conformational Switching of the Translocation Domain.
Toxins, 12, 2020
7K7D
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Crystal structure of diphtheria toxin from crystals obtained at pH 6.0
分子名称: Diphtheria toxin
著者Lovell, S, Kashipathy, M.M, Battaile, K.P, Rodnin, M.V, Ladokhin, A.S.
登録日2020-09-22
公開日2020-11-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of the Diphtheria Toxin at Acidic pH: Implications for the Conformational Switching of the Translocation Domain.
Toxins, 12, 2020
7K7C
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Crystal structure of diphtheria toxin from crystals obtained at pH 5.5
分子名称: Diphtheria toxin
著者Lovell, S, Kashipathy, M.M, Battaile, K.P, Rodnin, M.V, Ladokhin, A.S.
登録日2020-09-22
公開日2020-11-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structure of the Diphtheria Toxin at Acidic pH: Implications for the Conformational Switching of the Translocation Domain.
Toxins, 12, 2020
7K7B
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Crystal structure of diphtheria toxin from crystals obtained at pH 5.0
分子名称: Diphtheria toxin
著者Lovell, S, Kashipathy, M.M, Battaile, K.P, Rodnin, M.V, Ladokhin, A.S.
登録日2020-09-22
公開日2020-11-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structure of the Diphtheria Toxin at Acidic pH: Implications for the Conformational Switching of the Translocation Domain.
Toxins, 12, 2020
5I82
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First Crystal Structure of E.coli Based Recombinant Diphtheria Toxin Mutant CRM197
分子名称: Diphtheria toxin, GLYCEROL, SULFATE ION
著者Minasov, G, Shuvalova, L, Mishra, R.P.N, Goel, A, Dubrovska, I, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2016-02-18
公開日2016-03-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural and immunological characterization of E. coli derived recombinant CRM 197 protein used as carrier in conjugate vaccines.
Biosci.Rep., 38, 2018
4AE1
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Crystal structure of diphtheria toxin mutant CRM197 in complex with nicotinamide
分子名称: DIPHTHERIA TOXIN, NICOTINAMIDE
著者Malito, E, Spraggon, G.
登録日2012-01-04
公開日2012-03-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.078 Å)
主引用文献Structural Basis for Lack of Toxicity of the Diphtheria Toxin Mutant Crm197.
Proc.Natl.Acad.Sci.USA, 109, 2012
4AE0
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Crystal structure of diphtheria toxin mutant CRM197
分子名称: DIPHTHERIA TOXIN
著者Malito, E, Spraggon, G.
登録日2012-01-04
公開日2012-03-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.996 Å)
主引用文献Structural Basis for Lack of Toxicity of the Diphtheria Toxin Mutant Crm197.
Proc.Natl.Acad.Sci.USA, 109, 2012
1XDT
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COMPLEX OF DIPHTHERIA TOXIN AND HEPARIN-BINDING EPIDERMAL GROWTH FACTOR
分子名称: DIPHTHERIA TOXIN, HEPARIN-BINDING EPIDERMAL GROWTH FACTOR
著者Louie, G.V, Yang, W, Bowman, M.E, Choe, S.
登録日1997-11-18
公開日1998-02-25
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Crystal structure of the complex of diphtheria toxin with an extracellular fragment of its receptor.
Mol.Cell, 1, 1997
1TOX
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DIPHTHERIA TOXIN DIMER COMPLEXED WITH NAD
分子名称: DIPHTHERIA TOXIN (DIMERIC), NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Bell, C.E, Eisenberg, D.
登録日1995-10-06
公開日1996-06-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of diphtheria toxin bound to nicotinamide adenine dinucleotide.
Biochemistry, 35, 1996
1SGK
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NUCLEOTIDE-FREE DIPHTHERIA TOXIN
分子名称: DIPHTHERIA TOXIN (DIMERIC)
著者Bell, C.E, Eisenberg, D.
登録日1996-09-12
公開日1996-12-23
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of nucleotide-free diphtheria toxin.
Biochemistry, 36, 1997
1MDT
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THE REFINED STRUCTURE OF MONOMERIC DIPHTHERIA TOXIN AT 2.3 ANGSTROMS RESOLUTION
分子名称: ADENYLYL-3'-5'-PHOSPHO-URIDINE-3'-MONOPHOSPHATE, DIPHTHERIA TOXIN
著者Bennett, M.J, Eisenberg, D.
登録日1994-03-21
公開日1994-07-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Refined structure of monomeric diphtheria toxin at 2.3 A resolution.
Protein Sci., 3, 1994
1F0L
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1.55 ANGSTROM CRYSTAL STRUCTURE OF WILD TYPE DIPHTHERIA TOXIN
分子名称: ADENYLYL-3'-5'-PHOSPHO-URIDINE-3'-MONOPHOSPHATE, CHLORIDE ION, DIPHTHERIA TOXIN
著者Steere, B, Eisenberg, D.
登録日2000-05-16
公開日2000-11-16
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Characterization of High-Order Oligomerization and Energetics in Diphtheria Toxin
Thesis, 2001
1DTP
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THE STRUCTURE OF THE ISOLATED CATALYTIC DOMAIN OF DIPHTHERIA TOXIN
分子名称: ADENYLYL-3'-5'-PHOSPHO-URIDINE-3'-MONOPHOSPHATE, DIPHTHERIA TOXIN
著者Weiss, M.S, Eisenberg, D.
登録日1994-09-08
公開日1994-11-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of the isolated catalytic domain of diphtheria toxin.
Biochemistry, 34, 1995
1DDT
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THE REFINED STRUCTURE OF DIMERIC DIPHTHERIA TOXIN AT 2.0 ANGSTROMS RESOLUTION
分子名称: ADENYLYL-3'-5'-PHOSPHO-URIDINE-3'-MONOPHOSPHATE, DIPHTHERIA TOXIN
著者Bennett, M.J, Eisenberg, D.
登録日1994-03-01
公開日1994-07-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Refined structure of dimeric diphtheria toxin at 2.0 A resolution.
Protein Sci., 3, 1994

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