1UCP
 
 | | NMR structure of the PYRIN domain of human ASC | | 分子名称: | Apoptosis-associated speck-like protein containing a CARD | | 著者 | Liepinsh, E, Barbals, R, Dahl, E, Sharipo, A, Staub, E, Otting, G. | | 登録日 | 2003-04-16 | | 公開日 | 2003-11-04 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The death-domain fold of the ASC PYRIN domain, presenting a basis for PYRIN/PYRIN recognition
J.Mol.Biol., 332, 2003
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8ERT
 | | NLRP3 PYD filament | | 分子名称: | NACHT, LRR and PYD domains-containing protein 3 | | 著者 | Wu, H, Xiao, L. | | 登録日 | 2022-10-12 | | 公開日 | 2022-12-14 | | 最終更新日 | 2023-02-01 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Cryo-EM structures of the active NLRP3 inflammasome disc.
Nature, 613, 2023
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2YU0
 | | Solution structures of the PAAD_DAPIN domain of mus musculus interferon-activatable protein 205 | | 分子名称: | Interferon-activable protein 205 | | 著者 | Sato, M, Tochio, N, Koshiba, S, Watanabe, M, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-04-05 | | 公開日 | 2008-02-19 | | 最終更新日 | 2022-03-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the PAAD_DAPIN domain of mus musculus interferon-activatable protein 205
To be Published
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3J63
 | | Unified assembly mechanism of ASC-dependent inflammasomes | | 分子名称: | Apoptosis-associated speck-like protein containing a CARD | | 著者 | Lu, A, Magupalli, V.G, Ruan, J, Yin, Q, Atianand, M.K, Vos, M, Schroder, G.F, Fitzgerald, K.A, Wu, H, Egelman, E.H. | | 登録日 | 2013-12-05 | | 公開日 | 2014-03-26 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes.
Cell(Cambridge,Mass.), 156, 2014
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7K3R
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3QF2
 | | Crystal structure of NALP3 PYD | | 分子名称: | NACHT, LRR and PYD domains-containing protein 3 | | 著者 | Park, H.H, Bae, J.Y. | | 登録日 | 2011-01-21 | | 公開日 | 2011-08-31 | | 最終更新日 | 2011-11-23 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal Structure of NALP3 Protein Pyrin Domain (PYD) and Its Implications in Inflammasome Assembly
J.Biol.Chem., 286, 2011
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4EWI
 | | Crystal structure of the NLRP4 Pyrin domain | | 分子名称: | CHLORIDE ION, NACHT, LRR and PYD domains-containing protein 4, ... | | 著者 | Eibl, C, Hessenberger, M, Puehringer, S, Page, R, Diederichs, K, Peti, W. | | 登録日 | 2012-04-27 | | 公開日 | 2012-09-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Structural and Functional Analysis of the NLRP4 Pyrin Domain.
Biochemistry, 51, 2012
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7BSO
 | | Crystal structure of the human NLRP9 pyrin domain | | 分子名称: | NACHT, LRR and PYD domains-containing protein 9 | | 著者 | Park, H.H, Ha, H.J. | | 登録日 | 2020-03-31 | | 公開日 | 2021-02-10 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Crystal structure of the human NLRP9 pyrin domain reveals a bent N-terminal loop that may regulate inflammasome assembly.
Febs Lett., 594, 2020
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7PZD
 | | Cryo-EM structure of the NLRP3 PYD filament | | 分子名称: | NACHT, LRR and PYD domains-containing protein 3 | | 著者 | Hochheiser, I.V, Hagelueken, G, Behrmann, H, Behrmann, E, Geyer, M. | | 登録日 | 2021-10-12 | | 公開日 | 2022-04-20 | | 最終更新日 | 2022-05-25 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Directionality of PYD filament growth determined by the transition of NLRP3 nucleation seeds to ASC elongation.
Sci Adv, 8, 2022
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2DBG
 | | Solution structure of the Pyrin (PAAD-DAPIN) domain in human Myeloid cell nuclear differentiation antigen | | 分子名称: | Myeloid cell nuclear differentiation antigen | | 著者 | Saito, K, Inoue, M, Koshiba, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-12-15 | | 公開日 | 2006-06-15 | | 最終更新日 | 2022-03-09 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the Pyrin (PAAD-DAPIN) domain in human Myeloid cell nuclear differentiation antigen
To be Published
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2DO9
 | | Solution structure of the Pyrin/PAAD-DAPIN domain in mouse NALP10 (NACHT, leucine rich repeat and PYD containing 10) | | 分子名称: | NACHT-, LRR- and PYD-containing protein 10 | | 著者 | Saito, K, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-04-28 | | 公開日 | 2006-10-28 | | 最終更新日 | 2022-03-09 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the Pyrin/PAAD-DAPIN domain in mouse NALP10 (NACHT, leucine rich repeat and PYD containing 10)
To be Published
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7E5B
 | | Crystal structure of ASC PYD Domain and Rb-B7 | | 分子名称: | Apoptosis-associated speck-like protein containing a CARD, GLYCEROL, Repebody (Rb-B7) | | 著者 | Cho, H.S, Cha, J.S. | | 登録日 | 2021-02-18 | | 公開日 | 2022-03-02 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Oligomeric states of ASC specks regulate inflammatory responses by inflammasome in the extracellular space.
Cell Death Discov, 9, 2023
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6NCV
 | | Cryo-EM structure of NLRP6 PYD filament | | 分子名称: | NACHT, LRR and PYD domains-containing protein 6 | | 著者 | Shen, C, Fu, T.M, Wu, H. | | 登録日 | 2018-12-12 | | 公開日 | 2019-01-23 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Molecular mechanism for NLRP6 inflammasome assembly and activation.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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2N00
 | | NMR Solution structure of AIM2 PYD from Mus musculus | | 分子名称: | Interferon-inducible protein AIM2 | | 著者 | Hou, X, Niu, X. | | 登録日 | 2015-03-01 | | 公開日 | 2015-05-27 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The NMR solution structure of AIM2 PYD domain from Mus musculus reveals a distinct alpha 2-alpha 3 helix conformation from its human homologues
Biochem.Biophys.Res.Commun., 461, 2015
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2NAQ
 | | 3D NMR solution structure of NLRP3 PYD | | 分子名称: | NACHT, LRR and PYD domains-containing protein 3 | | 著者 | de Alba, E, Oroz, J. | | 登録日 | 2016-01-07 | | 公開日 | 2016-07-27 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | ASC Pyrin Domain Self-associates and Binds NLRP3 Protein Using Equivalent Binding Interfaces.
J.Biol.Chem., 291, 2016
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2N1F
 | | Structure and assembly of the mouse ASC filament by combined NMR spectroscopy and cryo-electron microscopy | | 分子名称: | Apoptosis-associated speck-like protein | | 著者 | Sborgi, L, Ravotti, F, Dandey, V, Dick, M, Mazur, A, Reckel, S, Chami, M, Scherer, S, Bockmann, A, Egelman, E, Stahlberg, H, Broz, P, Meier, B, Hiller, S. | | 登録日 | 2015-04-01 | | 公開日 | 2015-10-14 | | 最終更新日 | 2023-06-14 | | 実験手法 | ELECTRON MICROSCOPY (4 Å), SOLID-STATE NMR | | 主引用文献 | Structure and assembly of the mouse ASC inflammasome by combined NMR spectroscopy and cryo-electron microscopy.
Proc.Natl.Acad.Sci.USA, 112, 2015
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6Z2G
 | | Crystal structure of human NLRP9 PYD | | 分子名称: | NACHT, LRR and PYD domains-containing protein 9 | | 著者 | Marleaux, M, Anand, K, Geyer, M. | | 登録日 | 2020-05-15 | | 公開日 | 2020-06-10 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal structure of the human NLRP9 pyrin domain suggests a distinct mode of inflammasome assembly.
Febs Lett., 594, 2020
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4N1J
 | | Crystal structures of NLRP14 pyrin domain reveal a conformational switch mechanism, regulating its molecular interactions | | 分子名称: | GLYCEROL, NACHT, LRR and PYD domains-containing protein 14 | | 著者 | Eibl, C, Hessenberger, M, Wenger, J, Brandstetter, H. | | 登録日 | 2013-10-04 | | 公開日 | 2014-07-16 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structures of the NLRP14 pyrin domain reveal a conformational switch mechanism regulating its molecular interactions.
Acta Crystallogr.,Sect.D, 70, 2014
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4N1L
 | | Crystal structures of NLRP14 pyrin domain reveal a conformational switch mechanism, regulating its molecular interactions | | 分子名称: | NACHT, LRR and PYD domains-containing protein 14 | | 著者 | Eibl, C, Hessenberger, M, Wenger, J, Brandstetter, H. | | 登録日 | 2013-10-04 | | 公開日 | 2014-07-16 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.986 Å) | | 主引用文献 | Structures of the NLRP14 pyrin domain reveal a conformational switch mechanism regulating its molecular interactions.
Acta Crystallogr.,Sect.D, 70, 2014
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4N1K
 | | Crystal structures of NLRP14 pyrin domain reveal a conformational switch mechanism, regulating its molecular interactions | | 分子名称: | NACHT, LRR and PYD domains-containing protein 14 | | 著者 | Eibl, C, Hessenberger, M, Wenger, J, Brandstetter, H. | | 登録日 | 2013-10-04 | | 公開日 | 2014-07-16 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structures of the NLRP14 pyrin domain reveal a conformational switch mechanism regulating its molecular interactions.
Acta Crystallogr.,Sect.D, 70, 2014
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4O7Q
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4QOB
 | | Crystal structure of cPOP1 | | 分子名称: | Pyrin domain-containing protein 1 | | 著者 | Park, H.H. | | 登録日 | 2014-06-19 | | 公開日 | 2015-11-04 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of cPOP1
To be Published
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2HM2
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2KM6
 | | NMR structure of the NLRP7 Pyrin domain | | 分子名称: | NACHT, LRR and PYD domains-containing protein 7 | | 著者 | Pinheiro, A, Proell, M, Schwarzenbacher, R, Peti, W. | | 登録日 | 2009-07-21 | | 公開日 | 2010-06-09 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Three-dimensional structure of the NLRP7 pyrin domain: insight into pyrin-pyrin-mediated effector domain signaling in innate immunity.
J.Biol.Chem., 285, 2010
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2L6A
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