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8GIF
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BU of 8gif by Molmil
Crystal structure of a designed single-component Plasmodium falciparum AMA1-RON2L insertion fusion immunogen 3
分子名称: Apical membrane antigen 1, rhoptry neck protein 2 chimera
著者Patel, P.N, Tolia, N.H.
登録日2023-03-14
公開日2023-08-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure-based design of a strain transcending AMA1-RON2L malaria vaccine.
Nat Commun, 14, 2023
8GIE
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BU of 8gie by Molmil
Crystal structure of a designed single-component Plasmodium falciparum AMA1-RON2L insertion fusion immunogen 2
分子名称: Apical membrane antigen 1, rhoptry neck protein 2 chimera
著者Patel, P.N, Tolia, N.H.
登録日2023-03-14
公開日2023-08-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure-based design of a strain transcending AMA1-RON2L malaria vaccine.
Nat Commun, 14, 2023
8GID
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BU of 8gid by Molmil
Crystal structure of a strain-transcending single-component Plasmodium falciparum AMA1-RON2L structure-based design immunogen 1 (SBD1)
分子名称: Apical membrane antigen 1, rhoptry neck protein 2 chimera
著者Patel, P.N, Tolia, N.H.
登録日2023-03-14
公開日2023-08-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure-based design of a strain transcending AMA1-RON2L malaria vaccine.
Nat Commun, 14, 2023
8G6B
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BU of 8g6b by Molmil
Crystal structure of PfAMA1-RON2L chimera
分子名称: Apical membrane antigen 1, rhoptry neck protein 2 chimera, SULFATE ION
著者Boulanger, M.J, Ramaswamy, R.
登録日2023-02-14
公開日2023-09-13
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structure guided mimicry of an essential P. falciparum receptor-ligand complex enhances cross neutralizing antibodies.
Nat Commun, 14, 2023
6N87
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BU of 6n87 by Molmil
Plasmodium falciparum FVO apical membrane antigen 1 (AMA1) bound to MTSL spin-labelled cyclised RON2 peptide
分子名称: Apical membrane antigen-1, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate, backbone-cyclised peptide bcRON2hp
著者McGowan, S, Drinkwater, N.
登録日2018-11-28
公開日2019-01-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.588 Å)
主引用文献Identification of the Binding Site of Apical Membrane Antigen 1 (AMA1) Inhibitors Using a Paramagnetic Probe.
ChemMedChem, 14, 2019
6N7Q
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BU of 6n7q by Molmil
Plasmodium falciparum FVO apical membrane antigen 1 (AMA1) bound to cyclised RON2 peptide
分子名称: Apical membrane antigen-1, RON2 peptide
著者McGowan, S, Drinkwater, N.
登録日2018-11-28
公開日2019-01-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Identification of the Binding Site of Apical Membrane Antigen 1 (AMA1) Inhibitors Using a Paramagnetic Probe.
ChemMedChem, 14, 2019
5NQG
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BU of 5nqg by Molmil
Crystal structure of Plasmodium vivax AMA1 in complex with a 39 aa PvRON2 peptide
分子名称: Apical merozoite antigen 1, RON2
著者Vulliez-le Normand, B, Saul, F.A, Faber, B.W, Bentley, G.A.
登録日2017-04-20
公開日2017-09-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Cross-reactivity between apical membrane antgen 1 and rhoptry neck protein 2 in P. vivax and P. falciparum: A structural and binding study.
PLoS ONE, 12, 2017
5NQF
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BU of 5nqf by Molmil
Crystal structure of Plasmodium falciparum AMA1 in complex with a 39 aa PvRON2 peptide
分子名称: Apical membrane antigen 1, Rhoptry neck protein 2
著者Vulliez-le Normand, B, Saul, F.A, Faber, B.W, Bentley, G.A.
登録日2017-04-20
公開日2017-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Cross-reactivity between apical membrane antgen 1 and rhoptry neck protein 2 in P. vivax and P. falciparum: A structural and binding study.
PLoS ONE, 12, 2017
4Z81
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BU of 4z81 by Molmil
Crystal structure of AMA4 DI-DII-EGF1 from Toxoplasma gondii
分子名称: EGF family domain-containing protein, GLYCEROL
著者Parker, M.L, Boulanger, M.J.
登録日2015-04-08
公開日2015-12-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Dissecting the interface between apicomplexan parasite and host cell: Insights from a divergent AMA-RON2 pair.
Proc.Natl.Acad.Sci.USA, 113, 2016
4Z80
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BU of 4z80 by Molmil
Crystal structure of Toxoplasma gondii AMA4 DI-DII-EGF1 in complex with a 33 aa TgRON2L1 peptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cytoadherence-linked asexual protein, EGF family domain-containing protein, ...
著者Parker, M.L, Boulanger, M.J.
登録日2015-04-08
公開日2015-12-30
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Dissecting the interface between apicomplexan parasite and host cell: Insights from a divergent AMA-RON2 pair.
Proc.Natl.Acad.Sci.USA, 113, 2016
4Z0F
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BU of 4z0f by Molmil
Crystal structure of FVO strain Plasmodium falciparum AMA1 in complex with the RON2hp [Phe2038(6CW)] peptide
分子名称: Apical membrane antigen 1, Rhoptry neck protein 2
著者Wang, G, McGowan, S, Norton, R.S, Scanlon, M.J.
登録日2015-03-26
公開日2016-08-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
J.Mol.Biol., 428, 2016
4Z0E
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BU of 4z0e by Molmil
Crystal structure of FVO strain Plasmodium falciparum AMA1 in complex with the RON2hp [Phe2038TRN] peptide
分子名称: Apical membrane antigen 1, Rhoptry neck protein 2
著者Wang, G, McGowan, S, Norton, R.S, Scanlon, M.J.
登録日2015-03-26
公開日2016-08-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
J.Mol.Biol., 428, 2016
4Z0D
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BU of 4z0d by Molmil
Crystal structure of FVO strain Plasmodium falciparum AMA1 in complex with the RON2hp [Phe2038Trp] peptide
分子名称: Apical membrane antigen 1, Rhoptry neck protein 2
著者Wang, G, McGowan, S, Norton, R.S, Scanlon, M.J.
登録日2015-03-26
公開日2016-08-03
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
J.Mol.Biol., 428, 2016
4Z09
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BU of 4z09 by Molmil
Crystal structure of FVO strain Plasmodium falciparum AMA1 in complex with the RON2hp [Thr2040Ala] peptide
分子名称: Apical membrane antigen 1, GLYCEROL, Rhoptry neck protein 2
著者Wang, G, McGowan, S, Norton, R.S, Scanlon, M.J.
登録日2015-03-26
公開日2016-08-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
J.Mol.Biol., 428, 2016
4YIZ
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BU of 4yiz by Molmil
Crystal structure of engineered TgAMA1 lacking the DII loop in complex with an Eimeria tenella RON2D3 peptide
分子名称: 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Apical membrane antigen AMA1, ...
著者Parker, M.L, Boulanger, M.J.
登録日2015-03-02
公開日2015-05-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献An Extended Surface Loop on Toxoplasma gondii Apical Membrane Antigen 1 (AMA1) Governs Ligand Binding Selectivity.
Plos One, 10, 2015
4YIV
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BU of 4yiv by Molmil
Crystal structure of engineered TgAMA1 lacking the DII loop
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Apical membrane antigen AMA1, CADMIUM ION, ...
著者Parker, M.L, Boulanger, M.J.
登録日2015-03-02
公開日2015-05-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献An Extended Surface Loop on Toxoplasma gondii Apical Membrane Antigen 1 (AMA1) Governs Ligand Binding Selectivity.
Plos One, 10, 2015
4UV6
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BU of 4uv6 by Molmil
Crystal structure of apical membrane antigen 1 from Plasmodium knowlesi
分子名称: APICAL MEROZOITE ANTIGEN 1
著者Vulliez-Le Normand, B, Saul, F.A, Bentley, G.A.
登録日2014-08-04
公開日2015-04-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal Structure of Plasmodium Knowlesi Apical Membrane Antigen 1 and its Complex with an Invasion-Inhibitory Monoclonal Antibody.
Plos One, 10, 2015
4UAO
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BU of 4uao by Molmil
Crystal structure of Apical Membrane Antigen 1 from Plasmodium Knowlesi in complex with an invasion inhibitory antibody
分子名称: Apical merozoite antigen 1, immunoglobulin R31C2 VH and CH1 regions, immunoglobulin R31C2 light chain
著者Vulliez-Le Normand, B, Saul, F.A, Bentley, G.A.
登録日2014-08-11
公開日2015-04-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal Structure of Plasmodium knowlesi Apical Membrane Antigen 1 and Its Complex with an Invasion-Inhibitory Monoclonal Antibody.
Plos One, 10, 2015
4R1C
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BU of 4r1c by Molmil
Crystal Structure of 3D7 strain Plasmodium falciparum AMA1
分子名称: Apical membrane antigen 1, AMA1
著者Lim, S.S, Norton, R.S, McGowan, S.
登録日2014-08-04
公開日2015-01-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and Dynamics of Apical Membrane Antigen 1 from Plasmodium falciparum FVO.
Biochemistry, 53, 2014
4R1B
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BU of 4r1b by Molmil
Crystal Structure of 3D7 strain Plasmodium falciparum AMA1
分子名称: Apical membrane antigen 1, AMA1
著者Lim, S.S, Norton, R.S, McGowan, S.
登録日2014-08-04
公開日2015-01-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure and Dynamics of Apical Membrane Antigen 1 from Plasmodium falciparum FVO.
Biochemistry, 53, 2014
4R1A
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BU of 4r1a by Molmil
Crystal Structure of FVO strain Plasmodium falciparum AMA1
分子名称: Apical membrane antigen 1
著者Lim, S.S, Norton, R.S, McGowan, S.
登録日2014-08-04
公開日2015-01-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and Dynamics of Apical Membrane Antigen 1 from Plasmodium falciparum FVO.
Biochemistry, 53, 2014
4R19
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BU of 4r19 by Molmil
Crystal Structure of 3D7 strain Plasmodium falciparum AMA1
分子名称: Apical membrane antigen 1, AMA1
著者Lim, S.S, Norton, R.S, McGowan, S.
登録日2014-08-04
公開日2015-01-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure and Dynamics of Apical Membrane Antigen 1 from Plasmodium falciparum FVO.
Biochemistry, 53, 2014
4APM
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BU of 4apm by Molmil
Crystal Structure of AMA1 from Babesia divergens
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, APICAL MEMBRANE ANTIGEN 1, ...
著者Tonkin, M.L, Crawford, J, Lebrun, M.L, Boulanger, M.J.
登録日2012-04-04
公開日2012-12-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Babesia Divergens and Neospora Caninum Apical Membrane Antigen 1 (Ama1) Structures Reveal Selectivity and Plasticity in Apicomplexan Parasite Host Cell Invasion.
Protein Sci., 22, 2013
4APL
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BU of 4apl by Molmil
Crystal Structure of AMA1 from Neospora caninum
分子名称: APICAL MEMBRANE ANTIGEN 1
著者Tonkin, M.L, Crawford, J, Lebrun, M.L, Boulanger, M.J.
登録日2012-04-04
公開日2012-12-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Babesia Divergens and Neospora Caninum Apical Membrane Antigen 1 (Ama1) Structures Reveal Selectivity and Plasticity in Apicomplexan Parasite Host Cell Invasion.
Protein Sci., 22, 2013
3ZWZ
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BU of 3zwz by Molmil
Crystal structure of Plasmodium falciparum AMA1 in complex with a 39aa PfRON2 peptide
分子名称: APICAL MEMBRANE ANTIGEN 1, AMA1, GLYCEROL, ...
著者Vulliez-Le Normand, B, Tonkin, M.L, Lamarque, M.H, Langer, S, Hoos, S, Roques, M, Saul, F.A, Faber, B.W, Bentley, G.A, Boulanger, M.J, Lebrun, M.
登録日2011-08-03
公開日2012-07-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and Functional Insight Into the Malaria Parasite Moving Junction Complex
Plos Pathog., 8, 2012

 

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