PDB: 12 件ウェブページステータス検索Chemie searchBIRD

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2GFR	Solution structure of Amphibian tachykinin Uperolein bound to DPC micelles 分子名称: Uperolein 著者 Dike, A, Cowsik, S.M. 登録日 2006-03-23 公開日 2006-10-03 最終更新日 2019-12-25 実験手法 SOLUTION NMR 主引用文献 Solution structure of amphibian tachykinin Uperolein bound to DPC micelles. J.Struct.Biol., 156, 2006
8U26	Gaussian Mixture Models based single particle refinement - GPCR (Substance P bound to active human neurokinin 1 receptor in complex with miniGs399 from EMPIAR-10786) 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Chen, M, Pintilie, G. 登録日 2023-09-05 公開日 2023-11-15 最終更新日 2024-01-24 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Improving resolution and resolvability of single-particle cryoEM structures using Gaussian mixture models. Nat.Methods, 21, 2024
8JBH	Substance P bound to active human neurokinin 3 receptor in complex with Gq 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein Gq subunit alpha (G324), ... 著者 Sun, W.J, Yang, F, Zhang, H.H, Yuan, Q.N, Yin, W.C, Shi, P, Eric, X, Tian, C.L. 登録日 2023-05-08 公開日 2024-02-07 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural insights into neurokinin 3 receptor activation by endogenous and analogue peptide agonists. Cell Discov, 9, 2023
7VDM	Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with substance P 分子名称: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Li, Y, Yang, F. 登録日 2021-09-07 公開日 2021-12-01 最終更新日 2022-07-20 実験手法 ELECTRON MICROSCOPY (2.98 Å) 主引用文献 Structure, function and pharmacology of human itch receptor complexes. Nature, 600, 2021
4HOM	Crystal structure of porcine aminopeptidase-N complexed with substance P 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Chen, L, Lin, Y.L, Peng, G, Li, F. 登録日 2012-10-22 公開日 2012-10-31 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural basis for multifunctional roles of mammalian aminopeptidase N. Proc.Natl.Acad.Sci.USA, 109, 2012
7P00	Human Neurokinin 1 receptor (NK1R) substance P Gq chimera (mGsqi) complex 分子名称: Antibody fragment scFv16, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Thom, C, Ehrenmann, J, Vacca, S, Waltenspuhl, Y, Schoppe, J, Medalia, O, Pluckthun, A. 登録日 2021-06-29 公開日 2021-12-15 実験手法 ELECTRON MICROSCOPY (2.71 Å) 主引用文献 Structures of neurokinin 1 receptor in complex with G q and G s proteins reveal substance P binding mode and unique activation features. Sci Adv, 7, 2021
7P02	Human Neurokinin 1 receptor (NK1R) substance P Gs complex 分子名称: Antibody fragment scFv16, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Thom, C, Ehrenmann, J, Vacca, S, Waltenspuhl, Y, Schoppe, J, Medalia, O, Pluckthun, A. 登録日 2021-06-29 公開日 2021-12-15 実験手法 ELECTRON MICROSCOPY (2.87 Å) 主引用文献 Structures of neurokinin 1 receptor in complex with G q and G s proteins reveal substance P binding mode and unique activation features. Sci Adv, 7, 2021
7RMG	Substance P bound to active human neurokinin 1 receptor in complex with miniGs/q70 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Harris, J.A, Faust, B, Gondin, A.B, Daemgen, M.A, Suomivuori, C.M, Veldhuis, N.A, Cheng, Y, Dror, R.O, Thal, D, Manglik, A. 登録日 2021-07-27 公開日 2021-11-03 最終更新日 2022-01-05 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Selective G protein signaling driven by substance P-neurokinin receptor dynamics. Nat.Chem.Biol., 18, 2022
7RMH	Substance P bound to active human neurokinin 1 receptor in complex with miniGs399 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Harris, J.A, Faust, B, Gondin, A.B, Daemgen, M.A, Suomivuori, C.M, Veldhuis, N.A, Cheng, Y, Dror, R.O, Thal, D, Manglik, A. 登録日 2021-07-27 公開日 2021-11-03 最終更新日 2022-01-05 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Selective G protein signaling driven by substance P-neurokinin receptor dynamics. Nat.Chem.Biol., 18, 2022
2KSA	Substance P in DMPC/CHAPS isotropic q=0.25 bicelles as a ligand for NK1R 分子名称: Substance P, Substance-P receptor 著者 Gayen, A, Mukhopadhyay, C. 登録日 2009-12-31 公開日 2010-11-03 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 NMR evidence of GM1-induced conformational change of Substance P using isotropic bicelles Biochim.Biophys.Acta, 2010
2KS9	Solution conformation of substance P in water complexed with NK1R 分子名称: Substance P, Substance-P receptor 著者 Gayen, A, Mukhopadhyay, C. 登録日 2009-12-31 公開日 2010-11-03 最終更新日 2011-07-13 実験手法 SOLUTION NMR 主引用文献 NMR evidence of GM1-induced conformational change of Substance P using isotropic bicelles Biochim.Biophys.Acta, 2010
2KSB	Substance P in isotropic q=0.25 DMPC/CHAPS/GM1 bicelles as a ligand for NK1R 分子名称: Substance P, Substance-P receptor 著者 Gayen, A, Mukhopadhyay, C. 登録日 2009-12-31 公開日 2010-11-03 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 NMR evidence of GM1-induced conformational change of Substance P using isotropic bicelles Biochim.Biophys.Acta, 2010