7VH9
 
 | | Solution structure of the chimeric peptide of the first SURP domain of Human SF3A1 and the interacting region of SF1. | | 分子名称: | Splicing factor 3A subunit 1,Splicing factor 1 | | 著者 | Muto, Y, Kuwasako, K, Takizawa, M, Kobayashi, N, Sakamoto, T. | | 登録日 | 2021-09-21 | | 公開日 | 2022-09-28 | | 最終更新日 | 2023-10-25 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis for the interaction between the first SURP domain of the SF3A1 subunit in U2 snRNP and the human splicing factor SF1.
Protein Sci., 31, 2022
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1UG0
 | | Solution structure of SURP domain in BAB30904 | | 分子名称: | splicing factor 4 | | 著者 | He, F, Muto, Y, Ushikoshi, R, Koshiba, S, Shirouzu, M, Terada, T, Kigawa, T, Inoue, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Kobayashi, N, Tanaka, A, Osanai, T, Matsuo, Y, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-06-11 | | 公開日 | 2004-08-03 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of SURP domain in BAB30904
To be Published
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1X4O
 | | Solution structure of SURP domain in splicing factor 4 | | 分子名称: | Splicing factor 4 | | 著者 | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-05-14 | | 公開日 | 2005-11-14 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of SURP domain in splicing factor 4
To be Published
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2DT6
 | | Solution structure of the first SURP domain of human splicing factor SF3a120 | | 分子名称: | Splicing factor 3 subunit 1 | | 著者 | Kuwasako, K, He, F, Inoue, M, Tanaka, A, Sugano, S, Guentert, P, Muto, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-07-11 | | 公開日 | 2006-12-26 | | 最終更新日 | 2022-03-09 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the SURP domains and the subunit-assembly mechanism within the splicing factor SF3a complex in 17S U2 snRNP
Structure, 14, 2006
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2E5Z
 | | Solution structure of the surp2 domain in splicing factor, arginine/serine-rich 8 | | 分子名称: | Splicing factor, arginine/serine-rich 8 | | 著者 | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-12-25 | | 公開日 | 2007-06-26 | | 最終更新日 | 2022-03-09 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the surp2 domain in splicing factor, arginine/serine-rich 8
To be Published
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2E60
 | | Solution structure of the surp1 domain in splicing factor, arginine/serine-rich 8 | | 分子名称: | Splicing factor, arginine/serine-rich 8 | | 著者 | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-12-25 | | 公開日 | 2007-06-26 | | 最終更新日 | 2022-03-09 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the surp1 domain in splicing factor, arginine/serine-rich 8
To be Published
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4DGW
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2DT7
 | | Solution structure of the second SURP domain of human splicing factor SF3a120 in complex with a fragment of human splicing factor SF3a60 | | 分子名称: | Splicing factor 3 subunit 1, Splicing factor 3A subunit 3 | | 著者 | He, F, Kuwasako, K, Inoue, M, Guntert, P, Muto, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-07-11 | | 公開日 | 2006-12-26 | | 最終更新日 | 2022-03-09 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the SURP domains and the subunit-assembly mechanism within the splicing factor SF3a complex in 17S U2 snRNP
Structure, 14, 2006
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5NRL
 | | Structure of a pre-catalytic spliceosome. | | 分子名称: | 13 kDa ribonucleoprotein-associated protein, 23 kDa U4/U6.U5 small nuclear ribonucleoprotein component, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, ... | | 著者 | Plaschka, C, Lin, P.-C, Nagai, K. | | 登録日 | 2017-04-24 | | 公開日 | 2017-05-31 | | 最終更新日 | 2023-05-24 | | 実験手法 | ELECTRON MICROSCOPY (7.2 Å) | | 主引用文献 | Structure of a pre-catalytic spliceosome.
Nature, 546, 2017
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7EVO
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6QX9
 | | Structure of a human fully-assembled precatalytic spliceosome (pre-B complex). | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, AdML pre-mRNA, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Charenton, C, Wilkinson, M.E, Nagai, K. | | 登録日 | 2019-03-07 | | 公開日 | 2019-04-17 | | 最終更新日 | 2020-10-07 | | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | | 主引用文献 | Mechanism of 5' splice site transfer for human spliceosome activation.
Science, 364, 2019
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8CH6
 | | Structure of a late-stage activated spliceosome (BAqr) arrested with a dominant-negative Aquarius mutant (state B complex). | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... | | 著者 | Cretu, C, Schmitzova, J, Pena, V. | | 登録日 | 2023-02-07 | | 公開日 | 2023-05-10 | | 最終更新日 | 2023-06-14 | | 実験手法 | ELECTRON MICROSCOPY (5.9 Å) | | 主引用文献 | Structural basis of catalytic activation in human splicing.
Nature, 617, 2023
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7DCO
 | | Cryo-EM structure of the activated spliceosome (Bact complex) at an atomic resolution of 2.5 angstrom | | 分子名称: | BJ4_G0014900.mRNA.1.CDS.1, BJ4_G0027490.mRNA.1.CDS.1, BJ4_G0037700.mRNA.1.CDS.1, ... | | 著者 | Bai, R, Wan, R, Yan, C, Qi, J, Zhang, P, Lei, J, Shi, Y. | | 登録日 | 2020-10-26 | | 公開日 | 2021-03-17 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Mechanism of spliceosome remodeling by the ATPase/helicase Prp2 and its coactivator Spp2.
Science, 371, 2021
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8HK1
 | | The cryo-EM structure of human pre-17S U2 snRNP | | 分子名称: | ATP-dependent RNA helicase DDX42, HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, ... | | 著者 | Zhang, X, Zhan, X, Shi, Y. | | 登録日 | 2022-11-24 | | 公開日 | 2023-03-08 | | 最終更新日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Mechanisms of the RNA helicases DDX42 and DDX46 in human U2 snRNP assembly.
Nat Commun, 14, 2023
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7VPX
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7OQE
 | | Saccharomyces cerevisiae spliceosomal pre-A complex (delta BS-A ACT1) | | 分子名称: | 56 kDa U1 small nuclear ribonucleoprotein component, ACT1 pre-mRNA (delta BS-A), Cold sensitive U2 snRNA suppressor 1, ... | | 著者 | Zhang, Z, Rigo, N, Dybkov, O, Fourmann, J, Will, C.L, Kumar, V, Urlaub, H, Stark, H, Luehrmann, R. | | 登録日 | 2021-06-03 | | 公開日 | 2021-08-11 | | 最終更新日 | 2021-09-29 | | 実験手法 | ELECTRON MICROSCOPY (5.9 Å) | | 主引用文献 | Structural insights into how Prp5 proofreads the pre-mRNA branch site.
Nature, 596, 2021
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7OQB
 | | The U2 part of Saccharomyces cerevisiae spliceosomal pre-A complex (delta BS-A ACT1) | | 分子名称: | ACT1 pre-mRNA (delta-BS-A), Cold sensitive U2 snRNA suppressor 1, Pre-mRNA-processing ATP-dependent RNA helicase PRP5, ... | | 著者 | Zhang, Z, Rigo, N, Dybkov, O, Fourmann, J, Will, C.L, Kumar, V, Urlaub, H, Stark, H, Luehrmann, R. | | 登録日 | 2021-06-03 | | 公開日 | 2021-08-11 | | 最終更新日 | 2021-09-22 | | 実験手法 | ELECTRON MICROSCOPY (9 Å) | | 主引用文献 | Structural insights into how Prp5 proofreads the pre-mRNA branch site.
Nature, 596, 2021
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6FF7
 | | human Bact spliceosome core structure | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, BUD13 homolog, ... | | 著者 | Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H. | | 登録日 | 2018-01-03 | | 公開日 | 2019-03-13 | | 最終更新日 | 2020-10-07 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Structure and Conformational Dynamics of the Human Spliceosomal BactComplex.
Cell, 172, 2018
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8QO9
 | | Cryo-EM structure of a human spliceosomal B complex protomer | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, MINX pre-mRNA, Microfibrillar-associated protein 1, ... | | 著者 | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Urlaub, H, Stark, H, Luehrmann, R. | | 登録日 | 2023-09-28 | | 公開日 | 2024-01-24 | | 実験手法 | ELECTRON MICROSCOPY (5.29 Å) | | 主引用文献 | New insights into the functions of B complex proteins revealed by cryo-EM of dimerized
spliceosomes
To Be Published
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8Q7N
 | | cryo-EM structure of the human spliceosomal B complex protomer (tri-snRNP core region) | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, MINX pre-mRNA, Microfibrillar-associated protein 1, ... | | 著者 | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Urlaub, H, Stark, H, Luehrmann, R. | | 登録日 | 2023-08-16 | | 公開日 | 2024-01-24 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | New insights into the functions of B complex proteins revealed by cryo-EM of dimerized spliceosomes
To Be Published
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6G90
 | | Prespliceosome structure provides insight into spliceosome assembly and regulation (map A2) | | 分子名称: | 56 kDa U1 small nuclear ribonucleoprotein component, Cold sensitive U2 snRNA suppressor 1, Pre-mRNA-processing factor 39, ... | | 著者 | Plaschka, C, Lin, P.-C, Charenton, C, Nagai, K. | | 登録日 | 2018-04-10 | | 公開日 | 2018-08-22 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Prespliceosome structure provides insights into spliceosome assembly and regulation.
Nature, 559, 2018
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6Y53
 | | human 17S U2 snRNP low resolution part | | 分子名称: | HIV Tat-specific factor 1, Probable ATP-dependent RNA helicase DDX46, Small nuclear ribonucleoprotein E, ... | | 著者 | Zhang, Z, Will, C.L, Bertram, K, Luehrmann, R, Stark, H. | | 登録日 | 2020-02-24 | | 公開日 | 2020-06-17 | | 最終更新日 | 2020-07-22 | | 実験手法 | ELECTRON MICROSCOPY (7.1 Å) | | 主引用文献 | Molecular architecture of the human 17S U2 snRNP.
Nature, 583, 2020
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6Y5Q
 | | human 17S U2 snRNP | | 分子名称: | HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, Probable ATP-dependent RNA helicase DDX46, ... | | 著者 | Zhang, Z, Will, C.L, Bertram, K, Luehrmann, R, Stark, H. | | 登録日 | 2020-02-25 | | 公開日 | 2020-06-17 | | 最終更新日 | 2020-07-22 | | 実験手法 | ELECTRON MICROSCOPY (7.1 Å) | | 主引用文献 | Molecular architecture of the human 17S U2 snRNP.
Nature, 583, 2020
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7ABG
 | | Human pre-Bact-1 spliceosome | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Cell division cycle 5-like protein, ... | | 著者 | Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. | | 登録日 | 2020-09-07 | | 公開日 | 2020-12-23 | | 最終更新日 | 2020-12-30 | | 実験手法 | ELECTRON MICROSCOPY (7.8 Å) | | 主引用文献 | Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
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7ABI
 | | Human pre-Bact-2 spliceosome | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Beta-catenin-like protein 1, ... | | 著者 | Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. | | 登録日 | 2020-09-07 | | 公開日 | 2021-02-10 | | 実験手法 | ELECTRON MICROSCOPY (8 Å) | | 主引用文献 | Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
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