PDB: 17 件ウェブページステータス検索Chemie searchBIRD

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5O7E	Crystal structure of the peptidase domain of collagenase H from Clostridium histolyticum in complex with N-aryl mercaptoacetamide-based inhibitor 分子名称: CALCIUM ION, ColH protein, ZINC ION, ... 著者 Schoenauer, E, Brandstetter, H. 登録日 2017-06-08 公開日 2018-01-31 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Discovery of a Potent Inhibitor Class with High Selectivity toward Clostridial Collagenases. J. Am. Chem. Soc., 139, 2017
7ESI	Crystal structure of the collagenase unit of a Vibrio collagenase from Vibrio harveyi VHJR7 at 1. 8 angstrom resolution. 分子名称: CALCIUM ION, Collagenase unit (CU), Peptide P1, ... 著者 Cao, H.Y, Wang, Y, Peng, M, Zhang, Y.Z. 登録日 2021-05-11 公開日 2022-02-09 最終更新日 2023-02-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of Vibrio collagenase VhaC provides insight into the mechanism of bacterial collagenolysis. Nat Commun, 13, 2022
8JT1	COLLAGENASE FROM GRIMONTIA (VIBRIO) HOLLISAE 1706B COMPLEXED WITH GLY-PRO-HYP-GLY-PRO-HYP 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-mer peptide, ... 著者 Ueshima, S, Yaskawa, K, Takita, T, Mikami, B. 登録日 2023-06-21 公開日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Insights into the catalytic mechanism of Grimontia hollisae collagenase through structural and mutational analyses. Febs Lett., 597, 2023
2Y3U	Crystal structure of apo collagenase G from Clostridium histolyticum at 2.55 Angstrom resolution 分子名称: CITRATE ANION, COLLAGENASE, DI(HYDROXYETHYL)ETHER, ... 著者 Eckhard, U, Brandstetter, H. 登録日 2010-12-26 公開日 2011-09-28 最終更新日 2011-10-19 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structure of Collagenase G Reveals a Chew-and -Digest Mechanism of Bacterial Collagenolysis Nat.Struct.Mol.Biol., 18, 2011
2Y50	Crystal Structure of Collagenase G from Clostridium histolyticum at 2. 80 Angstrom Resolution 分子名称: CITRATE ANION, COLLAGENASE, HEXAETHYLENE GLYCOL, ... 著者 Eckhard, U, Brandstetter, H. 登録日 2011-01-11 公開日 2011-09-28 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of Collagenase G Reveals a Chew-and -Digest Mechanism of Bacterial Collagenolysis Nat.Struct.Mol.Biol., 18, 2011
2Y6I	Crystal Structure of Collagenase G from Clostridium histolyticum in complex with Isoamylphosphonyl-Gly-Pro-Ala at 3.25 Angstrom Resolution 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CITRATE ANION, COLLAGENASE, ... 著者 Eckhard, U, Brandstetter, H. 登録日 2011-01-21 公開日 2011-09-28 最終更新日 2015-09-16 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 Structure of Collagenase G Reveals a Chew-and -Digest Mechanism of Bacterial Collagenolysis Nat.Struct.Mol.Biol., 18, 2011
4ARF	CRYSTAL STRUCTURE OF THE PEPTIDASE DOMAIN OF COLLAGENASE H FROM CLOSTRIDIUM HISTOLYTICUM IN COMPLEX WITH THE PEPTIDIC INHIBITOR ISOAMYLPHOSPHONYL-GLY-PRO-ALA AT 1.77 ANGSTROM RESOLUTION. 分子名称: CALCIUM ION, COLH PROTEIN, ISOAMYLPHOSPHONYL-GLY-PRO-ALA, ... 著者 Eckhard, U, Brandstetter, H. 登録日 2012-04-23 公開日 2013-06-05 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Structural Basis for Activity Regulation and Substrate Preference of Clostridial Collagenases G, H, and T. J.Biol.Chem., 288, 2013
4AR1	Crystal Structure of the Peptidase Domain of Collagenase H from Clostridium histolyticum at 2.01 Angstrom resolution. 分子名称: CALCIUM ION, COLH PROTEIN, ZINC ION 著者 Eckhard, U, Brandstetter, H. 登録日 2012-04-20 公開日 2013-06-05 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Structural Basis for Activity Regulation and Substrate Preference of Clostridial Collagenases G, H, and T. J.Biol.Chem., 288, 2013
4AR9	Crystal structure of the peptidase domain of collagenase T from Clostridium tetani at 1.69 angstrom resolution. 分子名称: CALCIUM ION, COLLAGENASE COLT, ZINC ION 著者 Eckhard, U, Brandstetter, H. 登録日 2012-04-22 公開日 2013-06-05 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Structural Basis for Activity Regulation and Substrate Preference of Clostridial Collagenases G, H, and T. J.Biol.Chem., 288, 2013
4ARE	Crystal structure of the collagenase Unit of collagenase G from Clostridium histolyticum at 2.19 angstrom resolution. 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CITRATE ANION, COLLAGENASE G, ... 著者 Eckhard, U, Brandstetter, H. 登録日 2012-04-23 公開日 2013-06-05 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Structural Basis for Activity Regulation and Substrate Preference of Clostridial Collagenases G, H, and T. J.Biol.Chem., 288, 2013
4AR8	Crystal structure of the peptidase domain of collagenase T from Clostridium tetani complexed with the peptidic inhibitor isoamyl- phosphonyl-Gly-Pro-Ala at 2.05 angstrom resolution. 分子名称: CALCIUM ION, COLLAGENASE COLT, ISOAMYL-PHOSPHONYL-GLY-PRO-ALA, ... 著者 Eckhard, U, Brandstetter, H. 登録日 2012-04-21 公開日 2013-06-05 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural Basis for Activity Regulation and Substrate Preference of Clostridial Collagenases G, H, and T. J.Biol.Chem., 288, 2013
7VLZ	Crystal structure of the collagenase unit of a Vibrio collagenase from Vibrio harveyi VHJR7 分子名称: CALCIUM ION, Peptide P1, Peptide P2, ... 著者 Cao, H.Y, Wang, Y, Peng, M, Zhang, Y.Z. 登録日 2021-10-05 公開日 2022-10-19 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of the collagenase unit of a Vibrio collagenase from Vibrio harveyi VHJR7 To Be Published
7WSS	Collagenase from Grimontia (Vibrio) hollisae 1706B 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... 著者 Ikeuchi, T, Yasumoto, M, Takita, T, Mizutani, K, Mikami, B, Tanaka, K, Hattori, S, Yasukawa, K. 登録日 2022-02-01 公開日 2022-06-29 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Crystal structure of Grimontia hollisae collagenase provides insights into its novel substrate specificity toward collagen. J.Biol.Chem., 298, 2022
7XEB	Collagenase from Grimontia (Vibrio) hollisae 1706B complexed with Gly-Pro-Hyp 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, GLY-PRO-HYP peptide, ... 著者 Ikeuchi, T, Yasumoto, M, Takita, T, Mizutani, K, Mikami, B, Tanaka, K, Hattori, S, Yasukawa, K. 登録日 2022-03-30 公開日 2022-06-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Crystal structure of Grimontia hollisae collagenase provides insights into its novel substrate specificity toward collagen. J.Biol.Chem., 298, 2022
7ZBV	Crystal structure of the peptidase domain of collagenase G from Clostridium histolyticum in complex with a diphosphonate-based inhibitor 分子名称: CALCIUM ION, Collagenase ColG, TRIS-HYDROXYMETHYL-METHYL-AMMONIUM, ... 著者 Schoenauer, E, Brandstetter, H. 登録日 2022-03-24 公開日 2022-11-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Discovery and Characterization of Synthesized and FDA-Approved Inhibitors of Clostridial and Bacillary Collagenases. J.Med.Chem., 65, 2022
7Z5U	Crystal structure of the peptidase domain of collagenase G from Clostridium histolyticum in complex with a hydroxamate-based inhibitor 分子名称: (2~{R})-~{N}-[2-[4-[(2-acetamidophenoxy)methyl]-1,2,3-triazol-1-yl]ethyl]-2-(2-methylpropyl)-~{N}'-oxidanyl-propanediamide, CALCIUM ION, Collagenase ColG, ... 著者 Schoenauer, E, Brandstetter, H. 登録日 2022-03-10 公開日 2022-11-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Discovery and Characterization of Synthesized and FDA-Approved Inhibitors of Clostridial and Bacillary Collagenases. J.Med.Chem., 65, 2022
7ZOC	Crystal structure of the peptidase domain of collagenase H from Clostridium histolyticum in complex with N-aryl-2-alkylmercaptoacetamide-based inhibitor 分子名称: CALCIUM ION, Collagenase ColH, ZINC ION, ... 著者 Schoenauer, E, Brandstetter, H. 登録日 2022-04-25 公開日 2023-05-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 N-aryl-2-iso-butylmercaptoacetamides: the discovery of highly potent and selective inhibitors of P. aeruginosa virulence factor LasB and C. histolyticum virulence factor ColH To Be Published